Grantee Research Project Results
Research Centers
Carolina Center for Computational Toxicology
University of North Carolina at Chapel Hill
The Carolina Center for Computational Toxicology will advance the field of computational toxicology through the development of new methods and tools, as well as through collaborative efforts. To balance the research needs detailed in the RFA and maximize the interactions within the Center and between the Center and the larger environmental health community, the following sub-disciplines were recognized as critical to the Center:
- Biomedical modeling of chemical-perturbed networks (Project 1, PIs Gomez and Elston),
- Toxico-genetic modeling (Project 2, PIs Wright and Rusyn), and
- Chem-informatics (Project 3, PI Tropsha).
In each Project, new computer-based models will be developed and published that represent the state-of-the-art. The tools produced within each project will be widely disseminated, and the emphasis will be placed on their usability by the risk assessment community and the investigative toxicologists alike. The synthesis of data from a variety of sources will move the field of computational toxicology from a hypothesis-driven science toward a predictive science.
Additional information is available on the center website
View Projects in Tabular Format
Main Center Abstract and Reports:
Atlantic Coast Environmental Indicators Consortium
Consortium for Estuarine Ecoindicator Research for the Gulf of Mexico (CEER-GOM)
- Original Abstract
- 2001 Progress Report
- 2002 Progress Report
- 2003 Progress Report
- 2004 Progress Report
- Final Report
Center for Hazardous Substances in Urban Environments (CHSUE)
- Original Abstract
- 2002 Progress Report
- 2003 Progress Report
- 2004 Progress Report
- 2005 Progress Report
Western Region Hazardous Substance Research Center for Developing In-Situ Processes for VOC Remediation in Groundwater and Soil
- Original Abstract
- 2002 Progress Report
- 2003 Progress Report
- 2004 Progress Report
- 2005 Progress Report
- Final Report
Hazardous Substance Research Center–South and Southwest
- Original Abstract
- 2002 Progress Report
- 2003 Progress Report
- 2004 Progress Report
- 2005 Progress Report
- Final Report
Western Region Hazardous Substance Research Center
The Johns Hopkins University Center For The Asthmatic Child in the Urban Environment
CECEHDPR - University of Michigan
HSRC (1989) - Great Lakes/Mid-Atlantic HSRC
Hazardous Substance Research Center/South and Southwest
Center for Hazardous Substances in Urban Environments (CHSUE)
FDP - Center for Environmental Science
Carolina Environmental Bioinformatics Center
Johns Hopkins Particulate Matter Research Center
- Original Abstract
- 2006 Progress Report
- 2007 Progress Report
- 2008 Progress Report
- 2009 Progress Report
Harvard Particle Center
- Original Abstract
- 2006 Progress Report
- 2007 Progress Report
- 2008 Progress Report
- 2009 Progress Report
- Final Report
Texas Joint Center for Air Quality
- Original Abstract
- 2006 Progress Report
- 2007 Progress Report
- 2008 Progress Report
- 2009 Progress Report
- 2010 Progress Report
- Final Report
The Center for Advancing Microbial Risk Assessment (CAMRA)
Center for Integrating Statistical and Environmental Science
Inner City Toxicants, Child Growth and Development
Johns Hopkins Center for Childhood Asthma in the Urban Environment
- Original Abstract
- 2004 Progress Report
- 2005 Progress Report
- 2006 Progress Report
- 2007 Progress Report
- Final Report
Carolina Center for Computational Toxicology
- Original Abstract
- 2004 Progress Report
- 2005 Progress Report
- 2006 Progress Report
- 2007 Progress Report
- Final Report
The Center for Environmental Implications of Nanotechnology (CEINT)
Mechanisms of Asthma -- Dietary Interventions against Environmental Triggers
Center for Integrative Research on Childhood Leukemia and the Environment (CIRCLE)
- Original Abstract
- 2010 Progress Report
- 2011 Progress Report
- 2012 Progress Report
- 2013 Progress Report
- 2014 Progress Report
- Final Report
Center for Children’s Environmental Health and DiseasePreventionResearch (P01) (joint EPA and NIEHS) - CHAMACOS
- Original Abstract
- 2010 Progress Report
- 2011 Progress Report
- 2012 Progress Report
- 2013 Progress Report
- 2014 Progress Report
- Final Report
Berkeley/Stanford Children’s Environmental Health Center
- Original Abstract
- 2010 Progress Report
- 2011 Progress Report
- 2012 Progress Report
- 2013 Progress Report
- 2014 Progress Report
- 2015 Progress Report
- 2016 Progress Report
- Final Report
Perinatal Exposures, Epigenetics, Child Obesity & Sexual Maturation
Great Lakes Air Center for Integrative Environmental Research (GLACIER)
Air Pollution Mixtures: Health Effects Across Life Stages
- Original Abstract
- 2011 Progress Report
- 2012 Progress Report
- 2013 Progress Report
- 2014 Progress Report
- 2015 Progress Report
- 2016 Progress Report
- Final Report
National Environmental Respiratory Center
- Original Abstract
- 2010 Progress Report
- 2011 Progress Report
- 2012 Progress Report
- 2013 Progress Report
- 2014 Progress Report
- 2015 Progress Report
- 2016 Progress Report
- Final Report
Environmental Research and Technology Transfer Program of The Consortium for Plant Biotechnology Research, Inc.
Center for Reinventing Aging Infrastructure for Nutrient Management (RAINmgt)
Center for Comprehensive, optimaL, and Effective Abatement of Nutrients
- Original Abstract
- 2014 Progress Report
- 2015 Progress Report
- 2016 Progress Report
- 2017 Progress Report
- Final Report
Water Environment and Reuse Foundation (WE&RF)'s National Center for Resource Recovery and Nutrient Management
- Original Abstract
- 2014 Progress Report
- 2015 Progress Report
- 2016 Progress Report
- 2017 Progress Report
- Final Report
Lifecourse Exposures & Diet: Epigenetics, Maturation & Metabolic Syndrome
- Original Abstract
- 2014 Progress Report
- 2015 Progress Report
- 2016 Progress Report
- 2017 Progress Report
- Final Report
Children's Environmental Health & Disease Prevention Research Center at Dartmouth
- Original Abstract
- 2013 Progress Report
- 2014 Progress Report
- 2015 Progress Report
- 2016 Progress Report
- 2017 Progress Report
- Final Report
Water Innovation Network for Sustainable Small Systems (WINSSS)
- Original Abstract
- 2014 Progress Report
- 2015 Progress Report
- 2016 Progress Report
- 2017 Progress Report
- 2018 Progress Report
- Final Report
Cardiotoxicity Adverse Outcome Pathway: Organotypic Culture Model and in vitro-to-in vivo Extrapolation for High-throughput Hazard, Dose-response and Variability Assessments
- Original Abstract
- 2015 Progress Report
- 2016 Progress Report
- 2017 Progress Report
- 2018 Progress Report
- Final Report
SEARCH: Solutions to Energy, AiR, Climate, and Health
- Original Abstract
- 2015 Progress Report
- 2016 Progress Report
- 2017 Progress Report
- 2018 Progress Report
- 2019 Progress Report
- 2020 Progress Report
- Final Report
Comparing Urban and Rural Effects of Poverty on COPD (CURE COPD)
- Original Abstract
- 2016 Progress Report
- 2017 Progress Report
- 2018 Progress Report
- 2019 Progress Report
- 2020 Progress Report
- 2021 Progress Report
- Final Report
Center for Research on Early Childhood Exposure and Development in Puerto Rico
- Original Abstract
- 2016 Progress Report
- 2017 Progress Report
- 2018 Progress Report
- 2019 Progress Report
- 2020 Progress Report
- 2021 Progress Report
- Final Report
Center for the Study of Childhood Asthma in the Urban Environment (CCAUE)
- Original Abstract
- 2016 Progress Report
- 2017 Progress Report
- 2018 Progress Report
- 2019 Progress Report
- 2020 Progress Report
- 2021 Progress Report
- Final Report
A Sustainable Center for Crowd-Sourced Water Infrastructure Modeling
- Original Abstract
- 2016 Progress Report
- 2017 Progress Report
- 2018 Progress Report
- 2019 Progress Report
- 2020 Progress Report
- Final Report
Initial Annual CEMALB Progress Report: Human Health Effects of Environmental Pollutants
- Original Abstract
- 2017 Progress Report
- 2018 Progress Report
- 2019 Progress Report
- 2020 Progress Report
- 2021 Progress Report
- 2022 Progress Report
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.