Grantee Research Project Results
Research Centers
Michigan Center for the Environment and Childrens Health
University of Michigan
Childhood asthma is one of the most common chronic pediatric diseases and poses a serious public health problem. The prevalence of the disease in the city of Detroit is particularly high, reflecting the trends found elsewhere among urban populations and communities of color. The Michigan Center for the Environment and Children’s Health (MCECH) will engage in coordinated interdisciplinary research aimed at: 1) identifying children with asthma and assess their household, school, and neighborhood environment, 2) increasing knowledge and behavior to reduce environmental hazards in households and neighborhoods, thereby improving asthma-related health status, 3) examining the effects of daily and seasonal fluctuations in indoor and outdoor ambient air quality on pulmonary function and severity of asthma symptoms, 4) determining the effects of allergen-induced local, excessive production of chemokines on redox status and innervation of the bronchial tree, and 5) developing specific mechanisms for communication and translation of laboratory and community-based research across disciplines and to community partners. The Center will include three research cores, Asthma Intervention (Core 1), Asthma Exposure (Core 2) and Asthma Chemokines (Core 3), supported by two Facility Cores (Biostatistics and Exposure Assessment) and an Administrative Core, and two new Center Scientists.
The Center is a partnership involving the University of Michigan Schools of Public Health and Medicine, the Detroit Health Department, Henry Ford Health System, community-based organizations based on the southwest and east sides of Detroit, including Butzel Family Center, Community Health and Social Services Center (CHASS), Detroiters Working for Environmental Justice, Friends of Parkside, Kettering/Butzel Health Initiative, Latino Family Services, United Community Housing Coalition, and Warren/Conner Development Coalition, and the Centers for Disease Control and Prevention (CDC.) The Center builds on a partnership established in 1995 by the Detroit Community-Academic Urban Research Center (URC), one of three "Urban Centers for Applied Research" funded by the CDC. The Detroit URC seeks to develop and implement prevention research that improves the health of children and families in selected communities in southwest and east side Detroit. The Detroit URC Board, comprised of representatives of many of the same partners currently participating in the new Center, adopted a set of "Community-Based Research Principles" to guide the development of research projects carried out in conjunction with the URC. These research principles include an emphasis on: the local relevance of public health problems; the involvement of community, practitioner, and academic partners in all major phases of the research process; the conduct of research that is beneficial to the community involved; and the dissemination of research findings to community members in ways that are understandable and useful. In 1996 the URC Board, after a review of relevant data and discussion of interests and needs of partner organizations, identified three overall priority areas for developing new community-based prevention research projects. One of these priorities was the area of environmental health and in particular housing and air quality as it relates to asthma in children. The URC Board enthusiastically and unanimously decided to be involved in submitting a proposal for the new Center that would focus on identifying and reducing environmental exposures considered to be associated with asthma health status in children.
A description of the three core research projects, and an overview of the administrative structure and functions is provided below.
Identifier | Abstract | Principal Investigator |
Annual/ Final Reports |
Pubs Count | Institution | Grant Representative |
Grant Amount |
Project Period |
|
---|---|---|---|---|---|---|---|---|---|
1 |
EM834388
Centers - Main center abstract - The Consortium for Plant Biotechnology Research, Inc., Environmental Research and Technology Transfer Program |
Environmental Research and Technology Transfer Program of The Consortium for Plant Biotechnology Research, Inc. |
Bonning, Bryony C. Schumacher, Dorin Cheng, Zong-Ming Doty, Sharon Ellis, Deborah Landau Kessler, Michael Pantalone, Vincent R Paterson, Andrew Qu, Rongda Ren, Shuxin Robertson, Dominique Yang, Guochen - Principal Investigators listed are sub-PIs determined by the center. |
Row 1: 2011
|
Row 1 Total Pubs:
21 Row 1 Journals: 6 Row 1 Books: 1 |
Iowa State University, The Consortium for Plant Biotechnology Research, Inc, North Carolina State University, University of Georgia, University of Tennessee, University of Washington | Packard, Benjamin H | $1,706,000 |
January 01, 2009 - December 31, 2012 (Extended to December 31, 2013) |
2 |
R826709
Centers - Main center abstract - Center for Integrative Research on Childhood Leukemia and the Environment - 2015 |
Centers of Excellence in Children's Environmental Health and Disease Prevention Research |
Eskenazi, Brenda
- Principal Investigators listed are sub-PIs determined by the center. |
Row 2: 2001
|
Row 2 Total Pubs:
122 Row 2 Journals: 33 -- Row 2: No Books -- |
University of California - Berkeley | Callan, Richard | $2,830,746 |
August 01, 1998 - July 31, 2003 |
3 |
R828773
Centers - Main center abstract - Organotypic Culture Models For Predictive Toxicology Center |
Hazardous Substance Research Center–South and Southwest |
Reible, Danny D. Edge, Billy Fitzpatrick McCook, Leigh Hughes, Joseph B McCook, Leigh Fitzpatrick Pardue, J. - Principal Investigators listed are sub-PIs determined by the center. |
Row 3: 2002
|
Row 3 Total Pubs:
252 Row 3 Journals: 60 Row 3 Books: 26 |
Louisiana State University, Louisiana State University - Baton Rouge, Georgia Institute of Technology, Rice University, Texas A & M University, The University of Texas at Austin | Aja, Hayley | $5,550,000 |
October 01, 2001 - September 30, 2006 (Extended to September 30, 2007) |
4 |
R829402
Centers - Main center abstract - Center for Integrating Statistical and Environmental Science |
Center for Integrating Statistical and Environmental Science |
Stein, Michael Amit, Yali Beletsky, Dmitry Chay, Kenneth Dukic, Vanja Dwyer, Greg Eshel, Gidon Frederick, John Greenstone, Michael Kotamarthi, V. Rao Lesht, Barry McCullagh, Peter Meng, Xiao-Li Naureckas, Edward Pfister, Cathy Rathouz, Paul Reinsel, Gregory Schwab, David Solway, Julian Tiao, George Weatherhead, Elizabeth Wootton, Timothy Wuebbles, Donald J. - Principal Investigators listed are sub-PIs determined by the center. |
Row 4: 2004
|
Row 4 Total Pubs:
73 Row 4 Journals: 47 Row 4 Books: 1 |
University of Chicago, Argonne National Laboratory, National Oceanic and Atmospheric Administration, University of California - Berkeley, University of Colorado at Boulder, University of Illinois Urbana-Champaign, University of Miami, University of Wisconsin - Madison | Packard, Benjamin H | $6,250,049 |
March 12, 2002 - March 11, 2007 |
5 |
R829458
Centers - Main center abstract - EAGLES - Consortium for Estuarine Ecoindicator Research for the Gulf of Mexico |
Consortium for Estuarine Ecoindicator Research for the Gulf of Mexico (CEER-GOM) |
Brouwer, Marius Cheek, Ann Denslow, Nancy Grimes, Jay Han, Luoheng Heard, Richard Lepo, Joe Noble, Peter Nunez, Brian Scott Proctor, Lita Rakocinski, Chet Rose, Kenneth A. Snyder, Richard Thomas, Peter Yang, Xiaojun - Principal Investigators listed are sub-PIs determined by the center. |
Row 5: 2002
|
Row 5 Total Pubs:
21 Row 5 Journals: 17 Row 5 Books: 2 |
University of Southern Mississippi, Florida State University, Louisiana State University - Baton Rouge, Southeastern Louisiana University, The University of Alabama, The University of Texas at Austin, University of Florida, University of Washington, University of West Florida | Packard, Benjamin H | $5,906,323 |
December 01, 2001 - November 30, 2005 (Extended to May 20, 2007) |
6 |
R829480
Centers - Main center abstract - HSRC (2001) - South and Southwest HSRC |
Hazardous Substance Research Center/South and Southwest |
Reible, Danny D. Schmitter, Bob Ford, Denise Rousseau McCook, Leigh Fitzpatrick Stephens, F. Carol - Principal Investigators listed are sub-PIs determined by the center. |
Row 6: 2003
|
Row 6 Total Pubs:
19 -- Row 6: No Journals -- -- Row 6: No Books -- |
Georgia Institute of Technology, Louisiana State University - Baton Rouge, The University of Texas at Austin | Aja, Hayley | $382,000 |
October 01, 2001 - September 30, 2005 (Extended to September 30, 2006) |
7 |
R830093
Centers - Main center abstract - Center for Air, Climate, and Energy Solutions |
The Center for Environmental Implications of Nanotechnology (CEINT) |
Wiesner, Mark R.
- Principal Investigators listed are sub-PIs determined by the center. |
Duke University, Carnegie Mellon University, Clemson University, Howard University, North Carolina State University, Purdue University, Rice University, Stanford University, University of Kentucky, Virginia Tech | Hahn, Intaek | $1,000,000 |
September 01, 2008 - September 01, 2013 |
||
8 |
R831710
Centers - Main center abstract - Center for Integrative Research on Childhood Leukemia and the Environment - 2015 |
Center for Children's Environmental Health Research |
Eskenazi, Brenda Alkon, Abbey Barr, Dana Boyd Block, Gladys Boyce, Thomas Bradman, Asa Casida, John Cuevas, Maximiliano Das, Rupali Fenster, Laura Ginsberg, Gary Harley, Kim Harnly, Martha Hattis, Dale Holland, Nina T. Hubbard, Alan Jewell, Nicholas Johnson, Caroline Klein, Rachel Kreutzer, Richard Linde, Brian Lipsett, Michael Lubin, Bertram Macher, Janet Mattison, Donald McKone, Thomas Miller, Mark Steven Minkler, Meredith Mountain, Karen Raulet, David Robin, Renee Sedgwick, Jaqueline Sword, Elizabeth Tager, Ira Tunzi, Mark Wallestein, Nina Winkleby, Marilyn Young, John - Principal Investigators listed are sub-PIs determined by the center. |
Row 8: 2004
|
Row 8 Total Pubs:
157 Row 8 Journals: 131 Row 8 Books: 3 |
University of California - Berkeley | Callan, Richard | $6,665,538 |
May 01, 2004 - October 31, 2008 (Extended to October 31, 2010) |
9 |
R832362
Centers - Main center abstract - Duke University Center for Environmental Implications of NanoTechnology |
The Center for Advancing Microbial Risk Assessment (CAMRA) |
Rose, Joan B. Atwood, Michael Bolin, Carole Casman, Elizabeth Choi, Christopher Yeonsik Downs, Julie Gerba, Charles P. Gurian, Patrick Haas, Charles N. Han, Hyoi Hashsham, Syed Keim, Paul Koopman, James Nazaroff, William Nicas, Mark Pepper, Ian L. S. Eisenberg, Joseph N. Small, Mitchell J. Todd, Ewen Weber, Rosina - Principal Investigators listed are sub-PIs determined by the center. |
Row 9: 2007
|
Row 9 Total Pubs:
101 Row 9 Journals: 56 Row 9 Books: 2 |
Michigan State University, Carnegie Mellon University, Drexel University, Northern Arizona University, University of Arizona, University of California - Berkeley, University of Michigan | Packard, Benjamin H | $10,000,000 |
September 01, 2005 - August 31, 2010 |
10 |
R833825
Centers - Main center abstract - UT Center for Infrastructure Modeling and Management |
Carolina Center for Computational Toxicology |
Rusyn, Ivan Elston, Timothy Gomez, Shawn Gupta, Mayetri Nobel, Andrew Sun, Wei Tropsha, Alex Wang, Simon Wright, Fred A. Yeatts, Karin B. - Principal Investigators listed are sub-PIs determined by the center. |
Row 10: 2008
|
Row 10 Total Pubs:
98 Row 10 Journals: 63 Row 10 Books: 2 |
University of North Carolina at Chapel Hill, North Carolina State University | Hahn, Intaek | $3,400,000 |
April 01, 2008 - March 31, 2012 |
11 |
R834511
Centers - Main center abstract - Center for Integrative Research on Childhood Leukemia and the Environment - 2015 |
Center for Integrative Research on Childhood Leukemia and the Environment (CIRCLE) |
Buffler, Patricia Metayer, Catherine Barcellos, Lisa Chokkalingam, Anand Dahl, Gary Kyle, Amy Miller, Mark Rappaport, Stephen M. Selvin, Steve Wiemels, Joe Zhang, Luoping - Principal Investigators listed are sub-PIs determined by the center. |
Row 11: 2010
|
Row 11 Total Pubs:
52 Row 11 Journals: 13 -- Row 11: No Books -- |
University of California - Berkeley, Stanford University, University of California - San Francisco | Hahn, Intaek | $3,704,598 |
September 25, 2009 - September 24, 2015 |
12 |
R834513
Centers - Main center abstract - Center for the Health Assessment of Mothers and Children of Salinas - UC Berkeley School of Public Health: CHAMACOS Office, Berkeley, CA |
Center for Children’s Environmental Health and DiseasePreventionResearch (P01) (joint EPA and NIEHS) - CHAMACOS |
Eskenazi, Brenda Arora, Manish Barcellos, Lisa Barlow, Janice Blum, Arlene Bradman, Asa Chevrier, Jonathan Crinella, Frank Eisen, Ellen Fenster, Laura Harley, Kim Harnly, Martha Holland, Nina T. Hubbard, Alan Jerrett, Michael Johnson, Caroline Lustig, Robert McKone, Thomas Minkler, Meredith Molitor, John Rosas, Lisa Goldman Salvatore, Alicia Salvatore, Alicia L. Sjodin, Andreas Smith, Donald Wallerstein, Nina - Principal Investigators listed are sub-PIs determined by the center. |
Row 12: 2010
|
Row 12 Total Pubs:
514 Row 12 Journals: 156 -- Row 12: No Books -- |
University of California - Berkeley, Centers for Disease Control and Prevention, Harvard University, Natividad Medical Foundation, Oregon State University, University of California - Santa Cruz, University of New Mexico, ZERO Breast Cancer | Hahn, Intaek | $3,585,582 |
August 01, 2009 - July 31, 2014 (Extended to July 31, 2017) |
13 |
R834596
Centers - Main center abstract - UC Berkeley/Stanford Children’s Environment Health Center |
Berkeley/Stanford Children’s Environmental Health Center |
Hammond, S. Katharine Balmes, John R. Eisen, Ellen Gale, Sara L Gould, Jeffery Hubbard, Alan Lurmann, Fred Mann, Jennifer Mortimer, Kathleen Nadeau, Kari Noth, Elizabeth Padula, Amy Shaw, Gary M. Tager, Ira - Principal Investigators listed are sub-PIs determined by the center. |
Row 13: 2010
|
Row 13 Total Pubs:
49 Row 13 Journals: 15 -- Row 13: No Books -- |
University of California - Berkeley, Harvard University, Sonoma Technology, Inc., Stanford University, University of California - San Francisco | Callan, Richard | $1,091,783 |
May 07, 2010 - May 06, 2013 (Extended to May 06, 2014) |
14 |
R835435
Centers - Main center abstract - Center for Integrative Research on Childhood Leukemia and the Environment - 2015 |
UC Berkeley/Stanford Children's Environmental Health Center |
Hammond, S. Katharine Balmes, John R. Shaw, Gary M. - Principal Investigators listed are sub-PIs determined by the center. |
Row 14: 2014
|
Row 14 Total Pubs:
126 Row 14 Journals: 44 Row 14 Books: 1 |
University of California - Berkeley | Hahn, Intaek | $4,765,843 |
July 01, 2013 - June 30, 2018 (Extended to June 30, 2019) |
15 |
R835567
Centers - Main center abstract - Water Environment and Reuse Foundation's National Center for Resource Recovery and Nutrient Management |
Water Environment and Reuse Foundation (WE&RF)'s National Center for Resource Recovery and Nutrient Management |
Chandran, Kartik Olabode, Lola Pramanik, Amit Case, Traci L. Frear, Craig Khunjar, Wendell Luthy, Richard G. Radke, Christine Sedlak, David L. Skerlos, Steven J. Stack, William Stensel, David Wigginton, Krista Yorgey, Georgine - Principal Investigators listed are sub-PIs determined by the center. |
Row 15: 2014
|
Row 15 Total Pubs:
82 Row 15 Journals: 24 -- Row 15: No Books -- |
Columbia University in the City of New York, Water Environment and Reuse Foundation, Center for Watershed Protection, Hazen and Sawyer, Stanford University, University of California - Berkeley, University of Michigan, University of Washington, Washington State University, Water Research Foundation | Packard, Benjamin H | $3,370,298 |
November 01, 2013 - October 31, 2018 |
16 |
R835569
Centers - Main center abstract - Center for Reinventing Aging Infrastructure for Nutrient Management |
Center for Reinventing Aging Infrastructure for Nutrient Management (RAINmgt) |
Mihelcic, James R. Anderson, Damann Boyer, Treavor H. Butcher, Melissa Coney, Earnest Cornejo-Warner, Pablo Cunningham, Jeffrey A. Dao, Hang Davis, Allen Diaz-Elsayed, Nancy Dick, George Ergas, Sarina Henderson, Michelle Igielski, Sara Ishii, Stephanie Issacs, Wainella Kuwayama, Yusuke Locicero, Ryan Lopez, Emma Lynn, Thomas Mireles, Shelby Olmstead, Sheila Orner, Kevin Ozcan, Onur Payne, Karl Rankin, Laura Richardson, Nathan Rodriguez-Gonzalez, Laura Saetta, Daniella Schwartz, Sara Shih, Jhih-Shyang Trotz, Maya Wang, Ranran Xu, Jian Xu, Xiaofan Yeh, Daniel H Zhang, Qiong Zimmerman, Julie B. - Principal Investigators listed are sub-PIs determined by the center. |
Row 16: 2014
|
Row 16 Total Pubs:
87 Row 16 Journals: 20 Row 16 Books: 1 |
University of South Florida, Arizona State University, Corporation to Develop Communities of Tampa, Hazen and Sawyer, Resources for the Future, The University of Texas at Austin, University of Florida, University of Maryland - College Park, Yale University | Packard, Benjamin H | $3,123,375 |
September 01, 2013 - August 31, 2018 |
17 |
R835570
Centers - Main center abstract - UT Center for Infrastructure Modeling and Management |
Center for Comprehensive, optimaL, and Effective Abatement of Nutrients |
Arabi, Mazdak Bledsoe, Brian P. Hoag, Dana LK Hunt, William F Osmond, Deanna Sharvelle, Sybil Silversrein, JoAnn Vrugt, Jasper - Principal Investigators listed are sub-PIs determined by the center. |
Row 17: 2014
|
Row 17 Total Pubs:
137 Row 17 Journals: 36 -- Row 17: No Books -- |
Colorado State University, North Carolina State University, University of California - Irvine, University of Colorado at Boulder | Packard, Benjamin H | $2,200,151 |
September 01, 2013 - August 31, 2018 |
18 |
R835602
Centers - Main center abstract - Water Innovation Network for Sustainable Small Systems |
Water Innovation Network for Sustainable Small Systems (WINSSS) |
Reckhow, David A. Boyer, Treavor H. Brown, Jess Butler, Caitlin S. Dvorak, Bruce I. Katz, Lynn Kinney, Kerry A. Kirisits, Mary Jo Lai, Rebecca Lawler, Desmond Park, Chul Ray, Chittaranjan Saleh, Navid Shenoy, Prashant Speitel, Gerald E. Tobiason, John Wilson, Steven Zhang, Qiong - Principal Investigators listed are sub-PIs determined by the center. |
Row 18: 2015
|
Row 18 Total Pubs:
47 Row 18 Journals: 18 -- Row 18: No Books -- |
University of Massachusetts - Amherst, Carollo Engineers, The University of Texas at Austin, University of Florida, University of Illinois Urbana-Champaign, University of Nebraska at Lincoln, University of South Florida | Aja, Hayley | $4,100,000 |
August 01, 2014 - July 31, 2017 (Extended to July 31, 2019) |
19 |
R835802
Centers - Main center abstract - Organotypic Culture Models For Predictive Toxicology Center |
Cardiotoxicity Adverse Outcome Pathway: Organotypic Culture Model and in vitro-to-in vivo Extrapolation for High-throughput Hazard, Dose-response and Variability Assessments |
Rusyn, Ivan Threadgill, David W. Wright, Fred A. - Principal Investigators listed are sub-PIs determined by the center. |
Row 19: 2015
|
Row 19 Total Pubs:
144 Row 19 Journals: 41 -- Row 19: No Books -- |
Texas A & M University, Texas A & M University, North Carolina State University, The Hamner Institutes | Callan, Richard | $6,000,000 |
June 01, 2015 - May 31, 2019 (Extended to May 31, 2022) |
20 |
R835871
Centers - Main center abstract - Solutions for Energy, AiR, Climate and Health Center (SEARCH) |
SEARCH: Solutions to Energy, AiR, Climate, and Health |
Bell, Michelle L. Anastas, Paul T. Breysse, Patrick N. Curriero, Frank Deziel, Nicole Cardello Eckelman, Matthew J. Ellis, J. Hugh Esty, Daniel C. Gentner, Drew R. Gentry, Bradford S. Gillingham, Ken Gillingham, Kenneth Hobbs, Benjamin F. Katz, Howard Kerkez, Branko Koehler, Kirsten Peccia, Jordan Peng, Roger D. Son, Jiyoung Storelvmo, Trude Streets, David G. Wara, Michael W. Weyant, John P. Zaitchik, Ben Zhang, Yang Zhang, Yawei Zimmerman, Julie B. - Principal Investigators listed are sub-PIs determined by the center. |
Row 20: 2016
|
Row 20 Total Pubs:
118 Row 20 Journals: 73 -- Row 20: No Books -- |
Yale University, Argonne National Laboratory, Centers for Disease Control and Prevention, North Carolina State University, Northeastern University, Pacific Northwest National Laboratory, Stanford University, The Johns Hopkins University, University of Chicago, University of Michigan | Callan, Richard | $9,999,990 |
October 01, 2015 - September 30, 2020 (Extended to September 30, 2022) |
21 |
R835950
Centers - Main center abstract - Gulf Coast HSRC (Lamar) |
A Sustainable Center for Crowd-Sourced Water Infrastructure Modeling |
Hodges, Ben R. Abokifa, Ahmed A Ames, Daniel P. Barrett, Michael E. Berglund, Emily Brashear, Bob Cleveland, Theodore G. Faure, Julie Faust, Kasey Kandjani, Ehsan Madadi Leite, Fernanda Pechacek, Linda D Riano-Briceno, Gerardo Rowney, A. Charles Sela, Lina Tiernan, Edward Urbonas, Ben Xing, Lu Zhuang, Janice - Principal Investigators listed are sub-PIs determined by the center. |
Row 21: 2017
|
Row 21 Total Pubs:
90 Row 21 Journals: 24 Row 21 Books: 1 |
Brigham Young University, The University of Texas at Austin, North Carolina State University, Texas State University, Texas Tech University, University of Washington - Tacoma Branch, Urban Watersheds Research Institute | Packard, Benjamin H | $3,999,803 |
September 01, 2016 - August 31, 2021 (Extended to August 31, 2023) |
22 |
R836159
Centers - Main center abstract - Center for Integrative Research on Childhood Leukemia and the Environment - 2015 |
Center for Integrative Research on Childhood Leukemia and the Environment |
Metayer, Catherine
- Principal Investigators listed are sub-PIs determined by the center. |
Row 22: 2016
|
Row 22 Total Pubs:
35 Row 22 Journals: 35 -- Row 22: No Books -- |
University of California - Berkeley | Callan, Richard | $2,599,999 |
September 01, 2015 - August 31, 2019 (Extended to August 31, 2020) |
23 |
X832317
Centers - Main center abstract - UT Center for Infrastructure Modeling and Management |
Texas Joint Center for Air Quality |
Hitchcock, David Allen, David T. - Principal Investigators listed are sub-PIs determined by the center. |
Row 23: 2006
|
Row 23 Total Pubs:
11 Row 23 Journals: 3 -- Row 23: No Books -- |
Houston Advanced Research Center, The University of Texas at Austin | Chung, Serena | $969,300 |
September 01, 2005 - August 31, 2008 |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.