Grantee Research Project Results
Publications Details for Grant Number R831725
Metal Mixtures and Children’s Health
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Centers for Children's Environmental Health and Disease Prevention Research (2003)
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Reference Type | Citation | Progress Report Year | Document Sources |
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Abstract | Hu H, Brain J. Metal mixtures and children’s health. Epidemiology 2004;15(4):587-588. |
R831725 (2004) |
not available |
Book Chapter | Rodier PM. Neuroteratology of autism. In:Slikker Jr W, Chang LW, eds. Handbook of Developmental Neurotoxicology. San Diego, CA:Academic Press, 1998, Chapter 38, pp. 661-672. |
R824758 (Final) R831725 (2007) R831725 (2009) |
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Journal Article | Afeiche M, Peterson KE, Sanchez BN, Schnaas L, Cantonwine D, Ettinger AS, Solano-Gonzalez M, Hernandez-Avila M, Hu H, Tellez-Rojo MM. Windows of lead exposure sensitivity, attained height, and body mass index at 48 months. The Journal of Pediatrics 2012;160(6):1044-1049. |
R831725 (Final) R834800 (2012) R834800 (2013) |
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Journal Article | Arora M, Weuve J, Schwartz J, Wright RO. Association of environmental cadmium exposure with pediatric dental caries. Environmental Health Perspectives 2008;116(6):821-825. |
R831725 (2007) R831725 (2009) R831725 (Final) R831725C001 (2007) R831725C001 (2008) R831725C003 (2007) R831725C004 (2007) |
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Journal Article | Brain JD, Heilig E, Donaghey TC, Knutson MD, Wessling-Resnick M, Molina RM. Effects of iron status on transpulmonary transport and tissue distribution of Mn and Fe. American Journal of Respiratory Cell and Molecular Biology 2006;34(3):330-337. |
R831725 (2005) R831725 (2007) R831725 (2009) R831725 (Final) R831725C001 (2007) R831725C003 (2005) R831725C003 (2007) R831725C003 (2008) R831725C004 (2007) |
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Journal Article | Cantonwine D, Meeker JD, Hu H, Sanchez BN, Lamadrid-Figueroa H, Mercado-Garcia A, Fortenberry GZ, Calafat AM, Tellez-Rojo MM. Bisphenol A exposure in Mexico City and risk of prematurity:a pilot nested case control study. Environmental Health 2010;9:62. |
R831725 (Final) R834800 (2011) R834800 (2012) |
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Journal Article | Chou K, Wright RO. Phthalates in food and medical devices. Journal of Medical Toxicology 2006;2(3):126-135. |
R831725 (Final) |
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Journal Article | Heilig EA, Thompson KJ, Molina RM, Ivanov AR, Brain JD, Wessling-Resnick M. Manganese and iron transport across pulmonary epithelium. American Journal of Physiology–Lung Cellular and Molecular Physiology 2006;290(6):L1247-L1259. |
R831725 (2005) R831725 (2007) R831725 (2009) R831725 (Final) R831725C001 (2007) R831725C003 (2005) R831725C003 (2007) R831725C003 (2008) R831725C004 (2007) |
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Journal Article | Heilig E, Molina R, Donaghey T, Brain JD, Wessling-Resnick M. Pharmacokinetics of pulmonary manganese absorption: evidence for increased susceptibility to manganese loading in iron-deficient rats. American Journal of Physiology–Lung Cellular and Molecular Physiology 2005;288(5):L887-L893. |
R831725 (2007) R831725 (2009) R831725 (Final) R831725C001 (2007) R831725C003 (2005) R831725C003 (2007) R831725C004 (2007) |
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Journal Article | Hopkins MR, Ettinger AS, Hernandez-Avila M, Schwartz J, Tellez-Rojo MM, Lamadrid-Figueroa H, Bellinger D, Hu H, Wright RO. Variants in iron metabolism genes predict higher blood lead levels in young children. Environmental Health Perspectives 2008;116(9):1261-1266. |
R831725 (2009) R831725 (Final) R831725C001 (2008) |
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Journal Article | Hu H, Tellez-Rojo MM, Bellinger D, Smith D, Ettinger AS, Lamadrid-Figueroa H, Schwartz J, Schnaas L, Mercado-Garcia A, Hernandez-Avila M. Fetal lead exposure at each stage of pregnancy as a predictor of infant mental development. Environmental Health Perspectives 2006;114(11):1730-1735. |
R831725 (2007) R831725 (2009) R831725 (Final) |
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Journal Article | Hu H, Shine J, Wright RO. The challenge posed to children’s health by mixtures of toxic waste: the Tar Creek Superfund Site as a case-study. Pediatric Clinics of North America 2007;54(1):155-175. |
R831725 (2007) R831725 (2009) R831725 (Final) R831725C001 (2007) R831725C003 (2007) R831725C004 (2007) |
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Journal Article | Lanphear BP, Wright RO, Dietrich KN. Environmental neurotoxins. Pediatrics in Review 2005;26(6):191-198. |
R829389 (2003) R829389 (2004) R829389 (2005) R829389 (Final) R831725 (2009) R831725 (Final) R831725C001 (2005) |
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Journal Article | Oken E, Wright RO, Kleinman KP, Bellinger D, Amarasiriwardena CJ, Hu H, Rich-Edwards JW, Gillman MW. Maternal fish consumption, hair mercury, and infant cognition in a U.S. cohort. Environmental Health Perspectives 2005;113(10):1376-1380. |
R831725 (2007) R831725 (2009) R831725 (Final) R831725C001 (2005) |
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Journal Article | Ortega Garcia JA, Carrizo Gallardo D, Ferris i Tortajada J, Garcia MM, Grimalt JO. Meconium and neurotoxicants: searching for a prenatal exposure timing. Archives of Disease in Childhood 2006;91(8):642-646. |
R831725 (2009) |
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Journal Article | Ostrea Jr EM, Morales V, Ngoumgna E, Prescilla R, Tan E, Hernandez E, Ramirez GB, Cifra HL, Manlapaz ML. Prevalence of fetal exposure to environmental toxins as determined by meconium analysis. NeuroToxicology 2002;23(3):329-339. |
R831725 (2009) |
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Journal Article | Schaider LA, Senn DB, Brabander DJ, McCarthy KD, Shine JP. Characterization of zinc, lead, and cadmium in mine waste: implications for transport, exposure, and bioavailability. Environmental Science and Technology 2007;41(11):4164-4171. |
R831725 (2007) R831725 (2009) R831725 (Final) R831725C001 (2007) R831725C003 (2007) R831725C004 (2007) |
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Journal Article | Surkan PJ, Schnaas L, Wright RJ, Tellez-Rojo MM, Lamadrid-Figueroa H, Hu H, Hernandez-Avila EM, Bellinger DC, Schwartz J, Perroni E, Wright RO. Maternal self-esteem, exposure to lead, and child neurodevelopment. NeuroToxicology 2008;29(2):278-285. |
R831725 (2007) R831725 (2009) R831725 (Final) R831725C001 (2007) R831725C001 (2008) R831725C003 (2007) R831725C004 (2007) |
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Journal Article | Tellez-Rojo MM, Bellinger DC, Arroyo-Quiroz C, Lamadrid-Figueroa H, Mercado-Garcia A, Schnaas-Arrieta L, Wright RO, Hernandez-Avila M, Hu H. Longitudinal associations between blood lead concentrations lower than 10 μg/dL and neurobehavioral development in environmentally exposed children in Mexico City. Pediatrics 2006;118(2):e323-e330. |
R831725 (2007) R831725 (2009) R831725 (Final) R835441 (2017) |
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Journal Article | Thompson K, Molina RM, Brain JD, Wessling-Resnick M. Belgrade rats display liver iron loading. Journal of Nutrition 2006;136(12):3010-3014. |
R831725 (2007) R831725 (2009) R831725 (Final) R831725C001 (2007) R831725C003 (2007) R831725C003 (2008) R831725C004 (2007) |
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Journal Article | Thompson K, Molina R, Donaghey T, Brain JD, Wessling-Resnick M. The influence of high iron diet on rat lung manganese absorption. Toxicology and Applied Pharmacology 2006;210(1-2):17-23. |
R831725 (2005) R831725 (2007) R831725 (2009) R831725 (Final) R831725C001 (2007) R831725C003 (2005) R831725C003 (2007) R831725C003 (2008) R831725C004 (2007) |
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Journal Article | Thompson K, Molina RM, Donaghey T, Schwob JE, Brain JD, Wessling-Resnick M. Olfactory uptake of manganese requires DMT1 and is enhanced by anemia. FASEB Journal 2007;21(1):223-230. |
R831725 (2007) R831725 (2009) R831725 (Final) R831725C001 (2007) R831725C003 (2007) R831725C003 (2008) R831725C004 (2007) |
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Journal Article | Thompson K, Molina RM, Donaghey T, Brain JD, Wessling-Resnick M. Iron absorption by Belgrade rat pups during lactation. American Journal of Physiology-Gastrointestinal and Liver Physiology 2007;293(3):G640-G644. |
R831725 (2007) R831725 (2009) R831725 (Final) R831725C001 (2007) R831725C003 (2007) R831725C003 (2008) R831725C004 (2007) |
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Journal Article | Turker G, Ergen K, Karakoc Y, Arisoy AE, Barutcu UB. Concentrations of toxic metals and trace elements in the meconium of newborns from an industrial city. Biology of the Neonate 2006;89(4):244-250. |
R831725 (2009) |
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Journal Article | Wright RO, Amarasiriwardena C, Woolf AD, Jim R, Bellinger DC. Neuropsychological correlates of hair arsenic, manganese, and cadmium levels in school-age children residing near a hazardous waste site. NeuroToxicology 2006;27(2):210-216. |
R831725 (2005) R831725 (2007) R831725 (2009) R831725 (Final) R831725C001 (2005) |
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Journal Article | Wright RO, Baccarelli A. Metals and neurotoxicology. The Journal of Nutrition 2007;137(12):2809-2813. |
R831725 (2007) R831725 (2009) R831725 (Final) R831725C001 (2007) R831725C003 (2007) R831725C004 (2007) |
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Journal Article | Wright RO, Fields N. Therapeutics and toxicology. Current Opinion in Pediatrics 2008;20(2):171. |
R831725 (2009) R831725 (Final) R831725C001 (2008) |
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Journal Article | Wright RO. Neurotoxicology: what can context teach us? Journal of Pediatrics 2008;152(2):155-157. |
R831725 (2009) R831725 (Final) R831725C001 (2008) |
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Journal Article | Wright RO. New morbidities: new challenges. Current Opinion in Pediatrics 2009;21(2):220-221. |
R831725 (2009) R831725 (Final) R831725C001 (2008) |
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Journal Article | Zota AR, Ettinger AS, Bouchard M, Amarasiriwardena CJ, Schwartz J, Hu H, Wright RO. Maternal blood manganese levels and infant birth weight. Epidemiology 2009;20(3):367-373. |
R831725 (2009) R831725 (Final) R831725C001 (2008) |
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Journal Article | Collins JF, Wessling-Resnick M, Knutson MD. Hepcidin regulation of iron transport. The Journal of Nutrition 2008;138(11):2284-2288. |
R831725 (Final) |
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Journal Article | Zota AR, Willis R, Jim R, Norris GA, Shine JP, Duvall RM, Schaider LA, Spengler JD. Impact of mine waste on airborne respirable particulates in northeastern Oklahoma, United States. Journal of the Air & Waste Management Association 2009;59(11):1347-1357. |
R831725 (Final) |
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Journal Article | Pilsner R, Hu H, Ettinger A, Sanchez B, Wright R, Cantonwine D, Lazarus A, Lamadrid-Figueroa H, Mercado-García A, Téllez-Rojo MM, Hernández-Avila M. Influence of prenatal lead exposure on genomic methylation of cord blood DNA. Epidemiology 2009;20(6):S84. |
R831725 (Final) |
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Journal Article | Ettinger AS, Zota AR, Amarasiriwardena CJ, Hopkins MR, Schwartz J, Hu H, Wright RO. Maternal arsenic exposure and impaired glucose tolerance during pregnancy. Environmental Health Perspectives 2009;117(7):1059-1064. |
R831725 (Final) |
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Journal Article | Deb S, Johnson EE, Robalinho-Teixeira RL, Wessling-Resnick M. Modulation of intracellular iron levels by oxidative stress implicates a novel role for iron in signal transduction. Biometals 2009;22:855-862. |
R831725 (Final) |
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Journal Article | Sánchez BN, Hu H, Litman HJ, Téllez-Rojo MM. Statistical methods to study timing of vulnerability with sparsely sampled data on environmental toxicants. Environmental Health Perspectives 201;119(3):409-415. |
R831725 (Final) |
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Journal Article | Cantonwine D, Hu H, Sánchez BN, Lamadrid-Figueroa H, Smith D, Ettinger AS, Mercado-García A, Hernández-Avila M, Wright RO, Téllez-Rojo MM. Critical windows of fetal lead exposure:adverse impacts on length of gestation and risk of premature delivery. Journal of Occupational and Environmental Medicine 2010;52(11):1106-1111. |
R831725 (Final) |
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Journal Article | Cantonwine D, Hu H, Téllez-Rojo MM, Sánchez BN, Lamadrid-Figueroa H, Ettinger AS, Mercado-García A, Hernández-Avila M, Wright RO. HFE gene variants modify the association between maternal lead burden and infant birthweight:a prospective birth cohort study in Mexico City, Mexico. Environmental Health 2010;9:1-9. |
R831725 (Final) |
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Journal Article | Wessling-Resnick M. Iron homeostasis and the inflammatory response. Annual Review of Nutrition 2010;30(1):105-122. |
R831725 (Final) |
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Journal Article | Pilsner JR, Hu H, Wright RO, Kordas K, Ettinger AS, Sanchez BN, Cantonwine D, Lazarus AL, Cantoral A, Schnaas L, Tellez-Rojo MM. Maternal MTHFR genotype and haplotype predict deficits in early cognitive development in a lead-exposed birth cohort in Mexico City. The American Journal of Clinical Nutrition 2010;92(1):226-234. |
R831725 (Final) |
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Journal Article | Molina RM, Phattanarudee S, Kim J, Thompson K, Wessling-Resnick M, Maher TJ, Brain JD. Ingestion of Mn and Pb by rats during and after pregnancy alters iron metabolism and behavior in offspring. Neurotoxicology 2011;32(4):413-422. |
R831725 (Final) |
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Journal Article | Thompson KJ, Molina RM, Donaghey T, Savaliya S, Schwob JE, Brain JD. Manganese uptake and distribution in the brain after methyl bromide-induced lesions in the olfactory epithelia. Toxicological Sciences 2011;120(1):163-172. |
R831725 (Final) |
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Journal Article | Zota AR, Schaider LA, Ettinger AS, Wright RO, Shine JP, Spengler JD. Metal sources and exposures in the homes of young children living near a mining-impacted Superfund site. Journal of Exposure Science & Environmental Epidemiology 2011;21(5):495-505. |
R831725 (Final) |
not available |
Journal Article | Adamkiewicz G, Zota AR, Fabian MP, Chahine T, Julien R, Spengler JD, Levy JI. Moving environmental justice indoors:understanding structural influences on residential exposure patterns in low-income communities. American Journal of Public Health 2011;101(S1):S238-245. |
R831725 (Final) |
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Journal Article | Afeiche M, Peterson KE, Sánchez BN, Cantonwine D, Lamadrid-Figueroa H, Schnaas L, Ettinger AS, Hernández-Avila M, Hu H, Téllez-Rojo MM. Prenatal lead exposure and weight of 0-to 5-year-old children in Mexico City. Environmental Health Perspectives 2011;119(10):1436-1441. |
R831725 (Final) |
not available |
Journal Article | Sánchez BN, Kang S, Mukherjee B. A latent variable approach to study gene–environment interactions in the presence of multiple correlated exposures. Biometrics 2012;68(2):466-476. |
R831725 (Final) |
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Journal Article | Zhang A, Hu H, Sánchez BN, Ettinger AS, Park SK, Cantonwine D, Schnaas L, Wright RO, Lamadrid-Figueroa H, Tellez-Rojo MM. Association between prenatal lead exposure and blood pressure in children. Environmental Health Perspectives 2012;120(3):445-450. |
R831725 (Final) |
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Presentation | D Bellinger. Neuropsychological correlates of hair arsenic, manganese and cadmium levels in school-age children residing near a hazardous waste site. Presented to Miami, FL, November 17, 2005. |
R831725 (2005) |
not available |
Presentation | Estes E, McCarthey KD, Brabander DJ, Schaider LA, Shine JP. Hydrous ferric oxide transport processes during flood events: examples from the Tar Creek Superfund Site. Poster presented at the Geological Society of America, Northeastern Section Annual Meeting, Portand, ME, March 2009. |
R831725 (2009) R831725 (Final) R831725C002 (2008) |
not available |
Presentation | Hu H, Brain J. Metal mixtures and children’s health. Presented at the International Society for Environmental Epidemiology 16th Annual Conference, New York, NY, August 1-4, 2004. |
R831725 (2004) R831725 (Final) |
not available |
Presentation | Zota A, Ettinger AS, Amarasiriwardena C, Spengler JD, Bellinger D, Osborn M, Jim R, Hu H, Wright RO. Metal mixture biomarkers among mother-infant pairs living proximate to a Superfund mining site. Presented at the 17th Conference of the International Society for Environmental Epidemiology, Johannesburg, South Africa, September 13-16, 2005. |
R831725 (Final) R831725C002 (2005) |
not available |
Presentation | McCarthy DK, Brabander D, Schaider L, Argow B, Khoo M, Flynn N, Shine J. Evaluating the risk of exposure to Pb, Zn, and Cd after a major flood at a mining-impacted area. Presented at the Geological Society of America Annual Meeting, Houston, TX, October 2008. |
R831725 (2009) R831725 (Final) R831725C002 (2008) |
not available |
Presentation | Schaider LA, Senn DB, Brabander DJ, Holton MW, JP Shine. Metal speciation and mobility in mine waste piles and surface waters in a mine-impacted area. Presented at the Society of Environmental Toxicology and Chemistry 26th Annual Meeting, Baltimore, MD, November 13-17, 2005. |
R831725 (Final) R831725C002 (2005) |
not available |
Presentation | Zota AR, Ettinger AS, Schaider LA, Schwartz J, Wright RO, Spengler JD. Sources of metal exposure as predictors of body burden in infants living in a mining-impacted community. Presented at the 11th Annual Conference on Indoor Air Quality and Climate, Lyngby, Denmark, August 2008. |
R831725 (2009) R831725 (Final) R831725C002 (2008) |
not available |
Presentation | Zota A, Schaider LA, Brabander DJ, Wright RO, Osborn M, Spengler JD. Residential exposures to metals in homes near the Tar Creek Superfund Site. Presented at the 40th Annual Meeting of the Geological Society of America South-Central Section, Norman, OK, March 6-7, 2006. |
R831725 (Final) R831725C002 (2005) |
not available |
Presentation | Ettinger AS, Zota A, Spengler JD, Wright RO and H Hu. Assessment and control of metals exposures in the residential environment during the early stages of life. Presented at the 18th Annual International Conference on Environmental Epidemiology and Exposure, Paris, France, September 2006. |
R831725 (Final) |
not available |
Presentation | Zota A, Ettinger AS, Schaider LA, Wright RO, Brabander DJ, Osborn M, and JD Spengler. Children's exposure assessment study near a mining-related Superfund Site. Presented at the 134th Annual Meeting of the American Public Health Association, Boston, MA, November 2006. |
R831725 (Final) |
not available |
Presentation | Zota A. Remediation versus relocation:challenges of land preservation, community health, and social justice at the Tar Creek Superfund Site. Presented at the Conference on Conservation, Environmental Justice, and Resource Rights:Tensions and Overlaps, Boston, MA. October 2006. |
R831725 (Final) |
not available |
Presentation | Zota A, Paciorek C, Ettinger AS, Amarasiriwardena C, Spengler JD, Bellinger D, Osborn M, Hu H and RO Wright. Spatial variation in metal biomarkers of peripartum women near a mining-related Superfund Site. Presented at the 18th Annual International Conference on Environmental Epidemiology and Exposure, Paris, France, September 2006. |
R831725 (Final) |
not available |
Presentation | Khoo M, Schaider L, McCarthy K, Shine J, Senn D and D Brabander. Characterization of toxic metal transport processes downstream of the Tar Creek Superfund Site. Poster presented at the Geological Society of America, Northeastern Section Regional Meeting, Durham, NH, March 2007. |
R831725 (Final) |
not available |
Presentation | McCarthy K, Brabander D, Khoo M, Schaider L, Senn D and J Shine. Characterization of zinc, lead, and cadmium in a mine waste impacted area:Implications for fate and transport. Presented at the Geological Society of America Annual Meeting, Denver, CO, October 2007. |
R831725 (Final) |
not available |
Presentation | Schaider LA, Senn DB, Brabander DJ, McCarthy KD and JP Shine. Characterizing the lability and bioavailability of zinc, lead and cadmium in mine waste. Presented at the Society of Environmental Toxicology and Chemistry, North Atlantic Chapter Annual Meeting, Bristol, RI, June 2007. |
R831725 (Final) |
not available |
Presentation | Zota AR, Willis R, Shine JP, Jim R and JD Spengler. Sources of metals in ambient air particles in a former mining area in northeastern Oklahoma, USA. Presented at the 17th Annual Conference of the International Society of Exposure Analysis, Research Triangle Park, NC, November 2007. |
R831725 (Final) |
not available |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.