Publications for Center:

Organotypic Culture Models For Predictive Toxicology Center

Grant Number R835802

Journal Article (35)
Presentation (157)
Reference Type Citation Progress Report Year Document Sources
Journal Article Auerbach S, Filer D, Reif D, Walker V, Holloway AC, Schlezinger J, Srinivasan S, Svoboda D, Judson R, Bucher JR, Thayer KA. Prioritizing environmental chemicals for obesity and diabetes outcomes research: a screening approach using ToxCastTM high-throughput data. Environmental Health Perspectives 2016;124(8):1141-1154. R835802 (2015)
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Journal Article Barton-Maclaren TS, Westphal M, Sarwar E, Mattison D, Chiu WA, Dix D, Kavlock R, Krewski D. Challenges and opportunities in the risk assessment of existing substances in Canada: lessons learned from the international community. International Journal of Risk Assessment and Management 2017;20;(1-3):261-283. R835802 (2016)
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Journal Article Blanchette AD, Grimm FA, Dalaijamts C, Hsieh NH, Ferguson K, Luo YS, Anson B, Rusyn I, Chiu WA. Thorough QT/QTc in a dish:An in vitro human model that accurately predicts clinical concentration-QTc relationships. Clinical Pharmacology and Therapeutics 2019;105:1175-1186. R835802 (2018)
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Journal Article Bokkers BGH, Mengelers MJ, Bakker MI, Chiu WA, Slob W. APROBA-Plus: a probabilistic tool to evaluate and express uncertainty in hazard characterization and exposure assessment of substances. Food and Chemical Toxicology. 2017;110:408-417. R835802 (2017)
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Journal Article Chiu WA, Wright FA, Rusyn I. A tiered, Bayesian approach to estimating population variability for regulatory decision-making. ALTEX 2017;34(3):377-388. R835166 (2016)
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Journal Article Chiu WA, Axelrad DA, Dalaijamts C, Dockins C, Shao K, Shapiro AJ, Paoli G. Beyond the RfD:Broad application of a probabilistic approach to improve chemical dose-response assessments for noncancer effects. Environmental Health Perspective 2018;126(6):067009. R835802 (2018)
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Journal Article Chiu WA, Guyton KZ, Martin MT, Reif DM, Rusyn I. Use of high-throughput in vitro toxicity screening data in cancer hazard evaluations by IARC Monograph Working Groups. ALTEX 2018;35(1):51-64. R835802 (2017)
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Journal Article Chiu WA, Rusyn I. Advancing chemical risk assessment decision-making with population variability data: challenges and opportunities. Mammalian Genome 2018;29(1-2):182-189. R835802 (2017)
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Journal Article Cote I, Andersen ME, Ankley GT, Barone S, Birnbaum LS, Boekelheide K, Bois FY, Burgoon LD, Chiu WA, Crawford-Brown D, Crofton KM, DeVito M, Devlin RB, Edwards SW, Guyton KZ, Hattis D, Judson RS, Knight D, Krewski D, Lambert J, Maull EA, Mendrick D, Paoli GM, Patel CJ, Perkins EJ, Poje G, Portier CJ, Rusyn I, Schulte PA, Simeonov A, Smith MT, Thayer KA, Thomas RS, Thomas R, Tice RR, Vandenberg JJ, Villeneuve DL, Wesselkamper S, Whelan M, Whittaker C, White R, Xia M, Yauk C, Zeise L, Zhao J, DeWoskin RS. The next generation of risk assessment multi-year study--highlights of findings, applications to risk assessment, and future directions. Environmental Health Perspectives 2016;124(11):1671-1682. R835166 (Final)
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Journal Article Fantke P, Aylward L, Bare J, Chiu WA, Dodson R, Dwyer R, Ernstoff A, Howard B, Jantunen M, Jolliet O, Judson R, Kirchhübel N, Li D, Miller A, Paoli G, Price P, Rhomberg L, Shen B, Shin HM, Teeguarden J, Vallero D, Wambaugh J, Wetmore BA, Zaleski R, McKone TE. Advancements in life cycle human exposure and toxicity characterization. Environmetnal Health Perspective 2018;126:125001. R835802 (2018)
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Journal Article Garbutt TA, Konneker TI, Konganti K, Hillhouse AE, Swift-Haire F, Jones A, Phelps D, Aylor DL, Threadgill D. Permissiveness to form pluripotent stem cells may be an evolutionarily derived characteristic in Mus musculus. Scientific Reports 2018;8:14706. R835802 (2018)
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Journal Article Grimm FA, Iwata Y, Sirenko O, Bittner M, Rusyn I. High-content assay multiplexing for toxicity screening in induced pluripotent stem cell-derived cardiomyocytes and hepatocytes. Assay and Drug Development Technologies 2015;13(9):529-546. R835802 (2015)
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Journal Article Grimm FA, Iwata Y, Sirenko O, Chappell GA, Wright FA, Reif DM, Braisted J, Gerhold DL, Yeakley JM, Shepard P, Seligmann B, Roy T, Boogaard PJ, Ketelslegers HB, Rohde AM, Rusyn I. A chemical-biological similarity-based grouping of complex substances as a prototype approach for evaluating chemical alternatives. Green Chemistry 2016;18(16):4407-4419. R835166 (Final)
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Journal Article Grimm FA, Blanchette A, House JS, Ferguson K, Hsieh NH, Dalaijamts C, Wright AA, Anson B, Wright FA, Chiu WA, Rusyn I. A human population-based organotypic in vitro model for cardiotoxicity screening. ALTEX 2018;35:441-452. R835802 (2018)
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Journal Article Grimm FA, House JS, Wilson MR, Sirenko O, Iwata Y, Wright FA, Ball N, Rusyn I. Multi-Dimensional in Vitro Bioactivity Profiling for Grouping of Glycol Ethers. Regulatory Toxicology and Pharmacology 2019;101:91-102. R835166 (Final)
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Journal Article Grondin CJ, Davis AP, Wiegers TC, King BL, Wiegers JA, Reif DM, Hoppin JA, Mattingly CJ. Advancing exposure science through chemical data curation and integration in the Comparative Toxicogenomics Database. Environmental Health Perspectives 2016;124(10):1592-1599. R835802 (2015)
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Journal Article Guyton KZ, Rusyn I, Chiu WA, Corpet DE, van den Berg M, Ross MK, Christiani DC, Beland FA, Smith MT. Application of the key characteristics of carcinogens in cancer hazard identification. Carcinogenesis 2018;39(4):614-622. R835802 (2017)
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Journal Article House JS, Grimm FA, Jima DD, Zhou Y-H, Rusyn I, Wright FA. A pipeline for high-throughput concentration response modeling of gene expression for toxicogenomics. Frontiers in Genetics 2017;8:168 (11 pp.). R835802 (2017)
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Journal Article Iwata Y, Klaren WD, Lebakken CS, Grimm FA, Rusyn I. High-content assay multiplexing for vascular toxicity screening in induced pluripotent stem cell-derived endothelial cells and human umbilical vein endothelial cells. Assay and Drug Development Technologies 2017;15(6):267-279. R835166 (Final)
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Journal Article Judson R, Houck K, Martin M, Richard AM, Knudsen TB, Shah I, Little S, Wambaugh J, Woodrow Setzer R, Kothya P, Phuong J, Filer D, Smith D, Reif D, Rotroff D, Kleinstreuer N, Sipes N, Xia M, Huang R, Crofton K, Thomas RS. Editor's highlight: Analysis of the effects of cell stress and cytotoxicity on in vitro assay activity across a diverse chemical and assay space. Toxicological Sciences 2016;152(2):323-339. R835802 (2015)
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Journal Article Konganti K, Ehrlich A, Rusyn I, Threadgill DW. gQTL:a web application for QTL analysis using the collaborative cross mouse genetic reference population. G3:Genes, Genomes, Genetics 2018;8(8):2559-2562 R835802 (2017)
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Journal Article Li G, Shabalin AA, Rusyn I, Wright FA, Nobel AB. An empirical Bayes approach for multiple tissue eQTL analysis. Biostatistics 2018;19(3):391-406. R835802 (2017)
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Journal Article Marvel SW, To K, Grimm FA, Wright FA, Rusyn I, Reif DM. ToxPi Graphical User Interface 2.0: dynamic exploration, visualization, and sharing of integrated data models. BMC Bioinformatics 2018;19(1):80 (7 pp.). R835802 (2017)
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Journal Article Rusyn I, Greene N. The impact of novel assessment methodologies in toxicology on green chemistry and chemical alternatives. Toxicological Sciences 2018;161(2):276-284. R835802 (2017)
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Journal Article Shah I, Setzer RW, Jack J, Houck KA, Judson RS, Knudsen TB, Liu J, Martin MT, Reif DM, Richard AM, Thomas RS, Crofton KM, Dix DJ, Kavlock RJ. Using ToxCast™ data to reconstruct dynamic cell state trajectories and estimate toxicological points of departure. Environmental Health Perspectives 2016;124(7):910-919. R835802 (2015)
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Journal Article Sirenko O, Grimm FA, Ryan KR, Iwata Y, Chiu WA, Parham F, Wignall JA, Anson B, Cromwell EF, Behl M, Rusyn I, Tice RR. In vitro cardiotoxicity assessment of environmental chemicals using an organotypic human induced pluripotent stem cell-derived model. Toxicology and Applied Pharmacology 2017;322:60-74. R835166 (Final)
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Journal Article Tilley SK, Reif DM, Fry RC. Incorporating ToxCast and Tox21 datasets to rank biological activity of chemicals at Superfund sites in North Carolina. Environment International 2017;101:19-26. R835802 (2017)
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Journal Article Wignall JA, Muratov E, Sedykh A, Guyton KZ, Tropsha A, Rusyn I, Chiu WA. Conditional Toxicity Value (CTV) predictor: an in silico approach for generating quantitative risk estimates for chemicals. Environmental Health Perspectives 2018;126(5):057008 (13 pp.). R835802 (2017)
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Journal Article Zhang G, Marvel S, Truong L, Tanguay RL, Reif DM. Aggregate entropy scoring for quantifying activity across endpoints with irregular correlation structure. Reproductive Toxicology 2016;62:92-99. R835168 (Final)
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Journal Article Zhang G, Roell KR, Truong L, Tanguay RL, Reif DM. A data-driven weighting scheme for multivariate phenotypic endpoints recapitulates zebrafish developmental cascades. Toxicology and Applied Pharmacology 2017;314:109-117. R835168 (Final)
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Journal Article Zhou Y-H, Marron JS, Wright FA. Computation of ancestry scores with mixed families and unrelated individuals. Biometrics 2018;74(1):155-164. R835802 (2016)
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Journal Article Li G, Jima D, Wright FA, Nobel AB. HT-eQTL:integrative expression quantitative trait loci analysis in a large number of human tissues. BMC Bioinformatics 2018;19:95. R835802 (2018)
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Journal Article Kosnik MB, Reif DM. Determination of chemical-disease risk values to prioritize connections between environmental factors, genetic variants, and human diseases. Toxicology and Applied Pharmacology2019;379:114674. R835802C003 (2018)
Journal Article Kosnik MB, Planchart A, Marvel SW, Reif DM, Mattingly CJ. Integration of curated and high-throughput screening data to elucidate environmental influences on disease pathways. Computational Toxicology2019;12:100094. R835802C003 (2018)
Journal Article Hsieh NH, Reisfeld, B, Bois FY, Chiu WA. Applying a global sensitivity analysis workflow to improve the computational efficiencies in physiologically-based pharmacokinetic modeling. Frontiers in Pharmacology 2018 9:588. R835802 (2018)
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Presentation Blanchette A, Dalaijamts C, Grimm FA, Ferguson K, Anson B, Rusyn I Chiu WA. An in vitro human Bayesian Population Pharmacodynamic Model for predicting effects on heart rhythm. Poster presented at the Organotypic Culture Models for Predictive Toxicology Centers STAR Grantee Annual Meeting, Durham, NC, 2018. R835802 (2017)
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Presentation Botta D, Popp J, Farris L, Van Ness KP, White CC, Kelly EJ, Faustman EM, Rusyn I, Threadgill DW, Kavanagh TJ. Initial characterization of hepatocytes derived from Collaborative Cross recombinant inbred mouse strain iPSCs. Poster presented at the Organotypic Culture Models for Predictive Toxicology Centers STAR Grantee Annual Meeting, Durham, NC, 2018. R835802 (2017)
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Presentation Chiu WA, Guyton KZ, Martin MT, Reif DM, Rusyn I. Use of high throughput screening data in IARC monograph evaluations. Poster presented at the 50th Anniversary Meeting of the International Agency for Research on Cancer, Lyon, France, June 7-10, 2016. R835802 (2016)
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Presentation Chiu WA. Advancing risk assessment with genetic and population variability data. Presented at the Society of Toxicology 55th Annual Meeting and ToxExpo, New Orleans, LA, March 13-17, 2016. R835802 (2016)
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Presentation Chiu WA. Probabilistic dose-response assessment: basic principles and general approach developed by the WHO/IPCS. Poster presented at Society of Toxicology 55th Annual Meeting and ToxExpo, New Orleans, LA, March 13-17, 2016. R835802 (2016)
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Presentation Chiu WA. Addressing uncertainty, variability, susceptibility and risk in the 21st Century: the union of two NAS reports? Presented at the Society of Toxicology, Occupational and Public Health Specialty Section Luncheon, New Orleans, LA, March 2016. R835802 (2016)
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Presentation Chiu WA. Addressing population variability and susceptibility in risk assessment. Presented at the Risk Assessment of Tobacco Products: A Public Workshop, Hyattsville, MD, November 15-16, 2016. R835802 (2016)
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Presentation Chiu WA. Next generation human health decision-making incorporating population and inter-individual variability. Poster presented at the Society for Risk Analysis Annual Meeting, San Diego, CA, December 11-15, 2016. R835802 (2016)
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Presentation Chiu WA. Challenges and opportunities in using IVIVE to quantify risk and improve decision-making. Presented at the 10th Congress on Alternatives and Animal Use in the Life Sciences, Seattle, WA, August 20-24, 2017. R835802 (2017)
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Presentation Chiu WA. A probabilistic hazard characterization framework for addressing uncertainty and variability. Presented at the National Academy of Sciences: Workshop on the Development of Guiding Principles for the Inclusion of Chronic Disease Endpoints in Future Dietary Reference Intake, Washington, DC, January 9, 2017. R835802 (2016)
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Presentation Chiu, WA. Using ToxCast data in support of the key characteristics of carcinogens: opportunities and Challenges. Presented at the Toxicology Forum 42nd Annual Winter Meeting, Washington, DC, January 29-31, 2018. R835802 (2017)
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Presentation Chiu WA, Ouyang O, Dalaijamts C, Axelrad DA, Dockins C, Paoli G. Broad application of a probabilistic dose-response framework to improve chemical risk assessment. Poster presented at the Society of Toxicology 57th Annual Meeting and ToxExpo, San Antonio, TX, March 11-15, 2018. R835802 (2017)
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Presentation Grimm FA, Iwata Y, Sirenko O, Russell WK, Luo Y, Crittenden C, Wright FA, Reif DM, Yeakley J, Seligmann B, Shepard P, Roy T, Boogaard PJ, Ketelslegers H, Rohde AM, Rusyn I. Categorization of UVCBs using chemical-biological read across. Poster presented at the Society of Toxicology 55th Annual Meeting and ToxExpo, New Orleans, LA, March 13-17, 2016. R835166 (2016)
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Presentation Grimm FA, Chiu W, Hsieh NH, Dalaijamts C, Burnett S, Anson B, Wright A, Wright F, Rusyn I. A population-based organotypic human in vitro model for cardiotoxicity testing. Poster presented at the Society of Toxicology 56th Annual Meeting and ToxExpo, Baltimore, MD, March 12-16, 2017. R835802 (2016)
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Presentation Grimm FA. Diversity in a dish: a human population-based organotypic in vitro model for cardiotoxicity testing. Presented via the Society of Toxicology: In Vitro and Alternative Methods Specialty Section Webinar Series, May 2017. R835802 (2017)
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Presentation Grimm FA, Klaren WK, Li X, House JS, Chiu W, Lehmler HJ, Robertson LW, Rusyn I. Cardiotoxicity screening of polychlorinated biphenyls and their major metabolites. Poster presented at the Society of Toxicology 57th Annual Meeting and ToxExpo, San Antonio, TX, March 11-15, 2018. R835802 (2017)
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Presentation Grimm F, Iwata Y, Sirenko O, Bittner M, Rusyn I. High-content assay multiplexing for toxicity screening in induced pluripotent stem cell-derived cardiomyocytes and hepatocytes. Poster presented at the Society for Biomolecular Imaging and Informatics Annual Meeting, Boston, MA, September 15-17, 2015. R835802 (2016)
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Presentation Grimm F. Diversity in a dish: a population-based organotypic in vitro model for cardiotoxicity testing. Presented at the Horizons and Challenges in Organotypic Culture Models for Predictive Toxicology Symposium at the Society of Toxicology 56th Annual Meeting and ToxExpo, Baltimore, MD, March 12-16, 2017. R835802 (2016)
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Presentation Herzler M, Chiu WA, Slob W. New WHO guidance on uncertainty in hazard characterization: a unified tiered approach integrating deterministic and probabilistic methods. Poster presented at the 3rd German Pharm-Tox Summit, Göttingen, Germany, February 26-March 3, 2016. R835802 (2016)
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Presentation House JS, Grimm FA, Jima D, Zhou YH, Rusyn I, Wright FA. High-throughput count based assessment of concentration response modeling and gene expression. Poster presented at the EPA Organotypic Culture STAR Grants Satellite Meeting at the Society of Toxicology 56th Annual Meeting and ToxExpo, Baltimore, MD, March 12-16, 2017. R835802 (2016)
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Presentation House JS. Assessing inter-individual variability with high-throughput transcriptomics. Presented at the Genetics and Environmental Mutagenesis Society (GEMS) Fall Symposium, Research Triangle Park, NC, November 7, 2017. R835802 (2017)
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Presentation House JS, Grimm FA, Jima D, Rusyn I,Wright FA. High-throughput concentration response modeling in iPSC-cardiomyocytes. Poster presented at the Organotypic Culture Models for Predictive Toxicology Centers Annual STAR Grantee Meeting, Durham, NC, 2018. R835802 (2017)
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Presentation Hsieh N, Chiu W, Pksensi R. An R Package to apply sensitivity analysis in pharmacokinetic modeling. Society of Toxicology Annual Meeting, Baltimore, MD, 2019. R835802 (2018)
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Presentation Iwata Y, Grimm F, Wilson M, Bittner M, Sirenko O, Rowlands JC, Ball N, Rusyn I. Toxicological categorization of P-and E-series glycol ethers using high-content screening of human induced pluripotent stem cell (iPSC)-derived cells. Poster presented at the Society of Toxicology 55th Annual Meeting and ToxExpo, New Orleans, LA, March 13-17, 2016. R835166 (2016)
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Presentation Iwata Y, Klaren W, Grimm FA, Rusyn I. A multi-dimensional high-throughput approach for toxicity evaluation of environmental chemicals in induced pluripotent stem cell-derived endothelial cells. Poster presented at the at the Society of Toxicology 56th Annual Meeting and ToxExpo, Baltimore, MD, March 12-16, 2017. R835802 (2016)
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Presentation Klaren WD, Iwata Y, Grimm F, Rusyn I. Development of a high-throughput multiplexed assay for determining chemical effects on macrophage function. Poster presented at the at the Society of Toxicology 56th Annual Meeting and ToxExpo, Baltimore, MD, March 12-16, 2017. R835802 (2016)
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Presentation Kosnik M, Planchart A, Marvel S, Reif D, Mattingly C. Integration of curated and high-throughput screening data to elucidate environmental influences on disease pathways. Poster presented at the Organotypic Culture Models for Predictive Toxicology Centers Annual STAR Grantee Meeting, Durham, NC, 2018. R835802 (2017)
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Presentation Popp J. Generation of a diverse population of murine iPSCs using Sendai virus vector. Presented at the Texas A&M Student Research Week, College Station, TX, April 2017. R835802 (2017)
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Presentation Poop J.Embryoid body-based OCM for cardiotoxicity testing. Presented at the Horizons and Challenges in Organotypic Culture Models for Predictive Toxicology Symposium at the Society of Toxicology 56th Annual Meeting and ToxExpo, Baltimore, MD, March 12-16, 2017. R835802 (2016)
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Presentation Popp J. In vitro cardiotoxicity testing using murine iPSC derived organoids from a genetic reference population. Presented at the Texas Genetics Society 44th Annual Meeting, April 27-29, 2017. R835802 (2017)
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Presentation Popp J. Generation of a diverse population of murine iPSCs using Sendai virus vector. Presented at the Texas A&M Regenerative Medicine Interest Group Meeting, College Station, TX, June 2017. R835802 (2017)
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Presentation Popp J, Threadgill DW. Linking in vitro-to-in vivo toxicity testing using genetically-matched organoids and mice from a novel genetic reference population. Poster presented at the Organotypic Culture Models for Predictive Toxicology Centers Annual STAR Grantee Meeting, Durham, NC, 2018. R835802 (2017)
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Presentation Reif DM. Leveraging the power of high-dimensional data for integrated screening and prioritization decisions. Presented at the European Chemicals Agency's Topical Scientific Workshop, Helsinki, Finland, April 19-20, 2016. R835802 (2016)
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Presentation Reif DM. Handling missing data in chemical prioritization and bioactivity profiling applications using ToxPi. Presented at the Society of Toxicology 55th Annual Meeting and ToxExpo, New Orleans, LA, March 13-17, 2016. R835802 (2016)
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Presentation Reif DM. Leveraging high-dimensional data to inform probabilistic dose-response estimates. Presented at the Society of Toxicology 55th Annual Meeting and ToxExpo, New Orleans, LA, March 13-17, 2016. R835802 (2016)
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Presentation Reif DM. Bioinformatics for linking social and environmental determinants of health. Presented at the University of Wollongong. Wollongong, Australia, April 2017. R835802 (2016)
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Presentation Reif DM. SEAZIT: overview of zebrafish screening data. Presented at the National Institute of Environmental Health Sciences (NIEHS), Durham, NC, April 2017. R835802 (2016)
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Presentation Reif DM. Integrating multiple sources of high-dimensional data to quantify effects of genetic variability in chemical risk assessment. Presented at the 41st Annual Winter Meeting of the Toxicology Forum, Washington, DC, February 6-8, 2017. R835802 (2016)
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Presentation Reif DM. Applying data science: basic sciences. Presented at the National Institute of Environmental Health Sciences (NIEHS) Data Science Retreat, Durham, NC, July 2017. R835802 (2016)
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Presentation Reif DM. Implications of population genetic diversity for safety assessment. Presented at OPENTOX USA 2017, Durham, NC, July 12-13, 2017. R835802 (2017)
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Presentation Reif DM. Analytical methods to distill useful information from high-throughput screening of chemicals. Presented at the Joint Meeting of the Neurotoxicity Society & International Neurotoxicology Association, Florianopolis, Brazil, May 20-24, 2017. R835802 (2016)
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Presentation Reif DM. Gene-environment interactions associated with differential susceptibility to chemical exposure. Presented at the Environmental Mutagenesis and Genomics Society (EMGS) 48th Annual Meeting, Raleigh, NC, September 9-13, 2017. R835802 (2017)
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Presentation Rusyn I. Categorization of UVCBs using chemical-biological read across. Presented at the European Chemicals Agency's Topical Scientific Workshop, Helsinki, Finland, April 19-20, 2016. R835802 (2016)
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Presentation Rusyn I. Chemical safety assessment using read-across: novel biological and chemical profiling methodologies. Presented at the International Council of Chemical Associations’ Long-Range Research Initiative (ICCA-LRI) and Japan’s National Institute of Health Sciences (NIHS) Workshop, Awaji, Japan, June 15-16, 2016. R835802 (2016)
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Presentation Rusyn I. Exploring the characterization of human variability with in vitro models. Presented at the International Conference on Toxicity Testing Alternatives & Translational Toxicology, Hangzhou, China, June 2016. R835802 (2016)
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Presentation Rusyn I. Categorization of UVCBs using chemical-biological read across. Presented at the Society of Toxicology 55th Annual Meeting and ToxExpo, New Orleans, LA, March 13-17, 2016. R835166 (Final)
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Presentation Rusyn I. Genetics for toxicologists: why should we care? Presented at the Society of Toxicology 55th Annual Meeting and ToxExpo, New Orleans, LA, March 13-17, 2016. R835802 (2016)
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Presentation Rusyn I. Toxicological categorization of p-and e-series glycol ethers using high-content screening of human induced pluripotent stem cell (iPSC)-derived cells. Presented at the Society of Toxicology 55th Annual Meeting and ToxExpo, New Orleans, LA, March 13-17, 2016. R835166 (Final)
R835802 (2017)
R835802 (2018)
not available
Presentation Rusyn I. Use of high throughput screening data in IARC monograph evaluations. Presented at the Society of Toxicology 55th Annual Meeting and ToxExpo, New Orleans, LA, March 13-17, 2016. R835802 (2016)
R835802 (2017)
R835802 (2018)
not available
Presentation Rusyn I, Chiu WA, Guyton KZ, Martin M, Reif D. Use of high throughput screening data in International Agency for Research on Cancer (IARC) monograph evaluations. Poster presented at the Society of Toxicology 55th Annual Meeting and ToxExpo, New Orleans, LA, March 13-17, 2016. R835802 (2016)
R835802 (2018)
not available
Presentation Rusyn I. A chemical–biological similarity-based grouping of complex substances using multi-dimensional high-content screening of human induced pluripotent stem cell (iPSC)-derived models. Presented at the Environmental Mutagenesis and Genomics Society's 47th Annual Meeting, Kansas City, MO, September 24-28, 2016. R835802 (2016)
R835802 (2017)
R835802 (2018)
not available
Presentation Rusyn I. A population-based organotypic human in vitro model for cardiotoxicity testing. Presented at the 10th Congress on Alternatives and Animal Use in the Life Sciences, Seattle, WA, August 20-24, 2017. R835802 (2017)
R835802 (2018)
R835802 (Final)
not available
Presentation Rusyn I. Read-across and grouping of complex substances using bioactivity data from human induced pluripotent stem cell (iPSC)-derived models. Presented at the 10th Congress on Alternatives and Animal Use in the Life Sciences, Seattle, WA, August 20-24, 2017. R835802 (2017)
R835802 (2018)
R835802 (Final)
not available
Presentation Rusyn I. The future of human health assessments: using new methodologies for better understanding of the health impacts of petroleum substances. Presented at the 12th Concawe Symposium, Antwerp, Belgium, March 20-21, 2017. R835802 (2016)
R835802 (2017)
R835802 (2018)
not available
Presentation Rusyn I. Using new methodologies for better understanding of the health impacts of new and complex chemistries. Presented via the EPA/NCER webinar, Washington, DC, May 2017. R835802 (2016)
R835802 (2017)
R835802 (2018)
not available
Presentation Rusyn I. Commercializing tissue chip technologies. Presented at Organs- and Tissues-on-Chips, Big Sky, MT, April 8-12, 2018. R835802 (2017)
R835802 (2018)
R835802 (Final)
not available
Presentation Rusyn I. Grouping of UVCBs using chemical-biological read-across: case study of petroleum substances. Presented at the Toxicology Forum 42nd Annual Winter Meeting, Washington, DC, January 29-31, 2018. R835802 (2017)
R835802 (2018)
R835802 (Final)
not available
Presentation Rusyn I. Exploring the characterization of human variability with in vivo and in vitro experimental models. Presented at the University of Pennsylvania 13th Annual Center of Excellence in Environmental Toxicology (CEET) Symposium, Philadelphia, PA, June 18, 2018. R835802 (2017)
R835802 (2018)
R835802 (Final)
not available
Presentation Rusyn I. Categorization of UVCBs using chemical-biological read-across. Presented at the Society of Toxicology 57th Annual Meeting and ToxExpo, San Antonio, TX, March 11-15, 2018. R835802 (2017)
R835802 (2018)
R835802 (Final)
not available
Presentation Sakolish C, Bell C, Weber E, Kelly E, Himmelfarb J, Mouneimne R, Wade T, Han A, Burghardt R, Chiu W, Rusyn I. The cross-laboratory testing of the 8 human proximal tubule chip. Poster presented at the Society of Toxicology 57th Annual Meeting and ToxExpo, San Antonio, TX, March 11-15, 2018. R835802 (2017)
R835802 (2018)
R835802 (Final)
not available
Presentation Threadgill D. Use of the collaborative cross mouse panel to assess the effect of genetic variability in the low-dose region of a TCDD-induced dose-response curve. Presented at the Society of Toxicology 55th Annual Meeting and ToxExpo, New Orleans, LA, March 13-17, 2016. R835802 (2016)
R835802 (2017)
R835802 (2018)
not available
Presentation To K, Nguyen A, Fry RC, Reif DM. Handling missing data in chemical prioritization and bioactivity profiling applications using ToxPi. Poster presented at the Society of Toxicology 55th Annual Meeting and ToxExpo, New Orleans, LA, March 13-17, 2016. R835802 (2016)
R835802 (2017)
R835802 (2018)
R835802C003 (2015)
not available
Presentation Warren MR, Threadgill DW. Population variability and the teratogenic effects of exposure to 2,3,7,8-tetracholordibenzo-p-dioxin during pregnancy. Poster presented at the Allied Genetics Conference, Orlando, FL, July 13-17, 2016. R835802 (2016)
R835802 (2017)
R835802 (2018)
R835802C002 (2015)
not available
Presentation Wilson MR, Rowlands JC, Ball N, Wignall JA, Fourches D, Rusyn I. Data integration and visualization for transparent communication of the category read across: glycol ethers case study. Poster presented at the International Council of Chemical Associations’ Long-Range Research Initiative (ICCA-LRI) Workshop, New Orleans, LA, June 16-17, 2015. R835802 (2016)
R835802 (2017)
R835802 (2018)
R835802C001 (2015)
not available
Presentation Wright FA. An update on eQTLs, and their tissue-specificity– what have we learned? Presented at the North Carolina State University Genetics Program Seminar Series, October 19, 2015. R835802 (2016)
R835802 (2017)
R835802 (2018)
not available
Presentation Wright FA. Integrative approaches for large-scale transcriptome-wide association studies. Presented at the American Society of Human Genetics Annual Meeting, Baltimore, MD, October 6-10, 2015. R835802 (2016)
R835802 (2017)
R835802 (2018)
not available
Presentation Wright FA. Basic concepts in genetics, heritability, genome-wide association, and related toxicology study designs. Presented at the Society of Toxicology 55th Annual Meeting and ToxExpo, New Orleans, LA, March 13-17, 2016. R835802 (2016)
R835802 (2017)
R835802 (2018)
not available
Presentation Wright FA. A TempOSeq pipeline for high throughput concentration response modeling of gene expression for toxicogenomics. Presented at the NIEHS National Toxicology Program Seminar, Research Triangle Park, NC, October 2017. R835802 (2017)
R835802 (2018)
R835802 (Final)
not available
Presentation Wright FA. High-throughput count based assessment of concentration response modeling and gene expression. Presented at the Peer Review of the Draft NTP Approach to Genomic Dose-Response (GDR) Modeling Workshop, Research Triangle Park, NC, October 23-25, 2017. R835802 (2017)
R835802 (2018)
R835802 (Final)
not available
Presentation Grimm FA, Iwata Y, Sirenko O, Russell WK, Luo Y, Crittenden C, Wright FA, Reif DM, Yeakley J, Seligmann B, Shepard P, Roy T, Boogaard PJ, Ketelslegers H, Rohde AM, Rusyn I. Categorization of UVCBs using chemical-biological read across. Society of Toxicology Annual Meeting, New Orleans, LA, 2016. R835802 (2018)
not available
Presentation Chiu WA. Next Generation Human Health Decision-Making Incorporating Population and Inter-individual Variability. Presented at the Society for Risk Analysis meeting, New Orleans, LA, 2016. R835802 (2018)
not available
Presentation Popp J. Generation and Use of Induced Pluripotent Stem Cells from a Genetically Heterogeneous Population. Texas A&M Regenerative Medicine Interest Group. College Station, TX, June 2017. R835802 (2018)
not available
Presentation Chen Z, Yanagisawa L, Chiu WA, Rusyn I. A multi-tissue organotypic human in vitro model for rapid hazard identification of environmental chemicals and mixtures. Presented at The Harvey Research Symposium, Corpus Christie, TX, 2018. R835802 (2018)
R835802 (Final)
R835802C001 (2018)
not available
Presentation Burnett S, Grimm F, Anson B, Wright FA, Chiu W, Rusyn I. An in vitro human population model for assessment of inter-individual variability in cardiotoxicity. Lone Star SOT Annual Meeting, Austin, TX, 2018. R835802 (2018)
R835802 (Final)
R835802C001 (2018)
not available
Presentation Chiu W. Application of the WHO-IPCS dose-response framework to the human toxicity component of life cycle impact analysis. Society for Risk Analysis Annual Meeting. Arlington, VA, December 2018. R835802 (2018)
R835802 (Final)
R835802C001 (2018)
not available
Presentation Chiu W. Beyond the RfD: Broad application of a probabilistic approach to improve chemical dose-response assessments for non-cancer effects. UC-SF Program on Reproductive Health and the Environment (PRHE) Rapid Response Network Meeting, November 2018. R835802 (2018)
R835802 (Final)
R835802C001 (2018)
not available
Presentation Wright FA. Building a bioinformatics-savvy workforce in environmental sciences. Workshop on Developing a Data Science Competent EHS Workforce, NIEHS, Research Triangle Park, NC, August 2018. R835802 (2018)
R835802 (Final)
not available
Presentation Wright FA. Data Handling and Integration. Concawe Cat-App Workshop, Brussels, Belgium, September 2018. R835802 (2018)
R835802 (Final)
not available
Presentation Kosnik MB, Planchart A, Reif DM, Mattingly CJ. Data integration techniques to elucidate connections between environmental factors, genetic variants, and human diseases. ASHG Annual Meeting, San Diego, CA, 2018. R835802 (2018)
R835802 (Final)
R835802C003 (2018)
not available
Presentation Chiu W. Development and use of quantitative adverse outcome pathways: lessons learned from application to cardiotoxicity. National Academies of Sciences Workshop: Strategies and tools for conducting systematic reviews of mechanistic data to support chemical assessments. Washington, DC, December 2018. R835802 (2018)
R835802 (Final)
R835802C001 (2018)
not available
Presentation Wright FA. Effect-size and multitissue models for cis-eQTLs. GTEx Meeting, NY Genome Center, New York City, May 2018. R835802 (2018)
R835802 (Final)
R835802C003 (2018)
not available
Presentation Reif DM. Searching for GxE in high-throughput data. Biology Seminar Series, East Carolina University Greenville, NC, October 2018. R835802 (2018)
R835802 (Final)
R835802C003 (2018)
not available
Presentation Blanchette A, Grimm F, Dalaijamts C, Hsieh NH, Ferguson K, Luo YS, Anson B, Rusyn I, Chiu WA. Thorough QT/QTC in a dish: An in vitro human model that accurately predicts clinical concentration-QTC relationships. Presented at the Lone Star SOT Annual Meeting, Austin, TX, 2018. R835802 (2018)
R835802 (Final)
R835802C001 (2018)
not available
Presentation Chiu W.Thorough QT/QTc in a dish: An in vitro human model that accurately predicts clinical concentration-QTc relationships. American Society for Cellular and Computational Toxicology webinar series, November 2018. R835802 (2018)
R835802 (Final)
R835802C001 (2018)
not available
Presentation Chiu W. Using ToxCast data in support of the key characteristics of carcinogens:opportunities and challenges. California EPA Cancer and Environmental Mixtures Meeting. Oakland, CA, August 2018. R835802 (2018)
R835802 (Final)
R835802C001 (2018)
not available
Presentation Chiu W. WHO/IPCS probabilistic approach to improve chemical dose-response assessments. Workshop on the Development of an Evidence Based Risk Assessment Framework. Ottawa, Canada, December 2018. R835802 (2018)
R835802 (Final)
R835802C001 (2018)
not available
Presentation Chen Z, Yanagisawa L, Liu Y, Camargo K, Casillas G, McDonald T, Horney J, Chiu WA, Rusyn I. A multi-tissue organotypic human in vitro model for rapid hazard identification of environmental chemicals and mixtures. Society of Toxicology Annual Meeting, Baltimore, MD 2019. R835802 (2018)
R835802 (Final)
R835802C001 (2018)
not available
Presentation Chiu W. Accurate clinical concentration-response predictions for cardiac arrhythmias using a population-based in vitro/in silico model. Department of Veterinary Physiology & Pharmacology Seminar. College Station, TX, February 2019. R835802 (2018)
R835802 (Final)
R835802C001 (2018)
not available
Presentation Popp J, Threadgill DW. Baseline cardiac phenotypes across a diverse population of mice: Implications for cardiotoxicity risk assessment. Society of Toxicology Annual Meeting, Baltimore, MD, 2019. R835802 (2018)
R835802 (Final)
not available
Presentation Burnett S, Blanchette A, Grimm F, Wright F, Chiu W, Rusyn I. Enabling Assessment of Cardiotoxicity Hazard for Environmental Chemicals Using An In Vitro Human Population Model. Society of Toxicology Annual Meeting, Baltimore, MD 2019. R835802 (2018)
R835802 (Final)
R835802C001 (2018)
not available
Presentation Danforth C, Craft E, Bolden A, Schultz K, Kwiatkowski C, Rusyn I, Chiu W. Evidence integration across multiple toxicity endpoints to prioritize constituents of potential concern in oil and gas produced water. Society of Toxicology Annual Meeting, Baltimore, MD, 2019. R835802 (2018)
R835802 (Final)
not available
Presentation Rusyn I. Mouse vs. Machine: Are animal studies being supplanted by computers? Society of Toxicology Annual Meeting, Baltimore, MD, March 2019. R835802 (2018)
R835802 (Final)
R835802C001 (2018)
not available
Presentation Kosnik MB. Multi concentration screening of ToxCast compounds for neurotoxicity using microelectrode arrays. EPA ToxCast Meeting. RTP, NC, February 2019. R835802 (2018)
R835802 (Final)
not available
Presentation Reisfeld B, Chiu W, Hsieh N, Ghosh S, Olschanowsky C, Bois F. POPKAT: A Framework for Bayesian Population PBPK Analysis. Society of Toxicology Annual Meeting, Baltimore, MD, 2019. R835802 (2018)
R835802 (Final)
R835802C001 (2018)
not available
Presentation Chiu W. Probabilistic Dose-Response Assessment Using the WHO/IPCS Framework. Training Workshop for California EPA/Department of Pesticide Regulation. Sacramento, CA, February 2019. R835802 (2018)
R835802 (Final)
R835802C001 (2018)
not available
Presentation Shao K, Chiu WA, Shapiro A. The Utility of Informative Prior in Benchmark Dose Modeling for Animal Reduction. Society of Toxicology Annual Meeting, Baltimore, MD, 2019. R835802 (2018)
R835802 (Final)
R835802C001 (2018)
not available
Presentation Chiu W. Thorough QT/QTc in a dish:An in vitro human model that accurately predicts clinical concentration-QTc relationships. Food and Drug Administration, Center for Drug Evaluation and Research, Pharmacology and Toxicology Reviewer Cardiac Journal Club, March 2019. R835802 (2018)
R835802 (Final)
R835802C001 (2018)
not available
Presentation Searching for GxE in high-throughput data. D.M. Reif. Biology Seminar Series, East Carolina University Greenville, NC, October 2018. R835802 (Final)
not available
Presentation Searching for GxE in high-throughput data. D.M. Reif. Biology Seminar Series, East Carolina University Greenville, NC, October 2018. R835802 (Final)
not available
Presentation Effect-size and Multitissue Models for cis-eQTLs. F.A. Wright. GTEx Meeting, NY Genome Center, New York City, May 2018. R835802 (Final)
not available
Presentation Effect-size and Multitissue Models for cis-eQTLs. F.A. Wright. GTEx Meeting, NY Genome Center, New York City, May 2018. R835802 (Final)
not available
Presentation Klaren WD, Grimm FA, Shen H, Rusyn I. In vitro approaches to grouping of complex substances and UVCBs: a case study of olefin streams. Poster presented at the Society of Toxicology 57th Annual Meeting and ToxExpo, San Antonio, TX, March 11-15, 2018. R835802 (2017)
R835802 (2018)
R835802 (Final)
not available
Presentation Botta D, Popp J, Farris L, Van Ness KP, White CC, Kelly EJ, Faustman EM, Rusyn I, Threadgill D and Kavanagh TJ (2018). Initial Characterization of Hepatocytes Derived from Collaborative Cross Recombinant Inbred Mouse Strain iPSCs. Presented at the U.S EPA:3rd Annual STAR Organotypic Culture Models (OCM) Progress Review Meeting, Durham, NC. R835738C003 (2018)
R835802 (2018)
R835802C001 (2018)
not available
Presentation Reif DM. ToxPi Graphical User Interface. U.S. EPA STAR Annual Meeting, Durham, NC, May 2018. R835802C003 (2018)
not available
Presentation Thorough QT/QTc in a Dish:An In Vitro Human Model That Accurately Predicts Clinical Concentration-QTc Relationships. W. Chiu. American Society for Cellular and Computational Toxicology webinar series. November 2018. R835802 (Final)
not available
Presentation Beyond the RfD:Broad Application of a Probabilistic Approach to Improve Chemical Dose-Response Assessments for Non-Cancer Effects. W. Chiu. UC-SF Program on Reproductive Health and the Environment (PRHE) Rapid Response Network Meeting. November 2018. R835802 (Final)
not available
Presentation Chiu W. Accurate clinical concentration-response predictions for cardiac arrhythmias using a population-based in vitro/in silico model. Laboratory Animal Sciences Virtual Event. Online Conference by Labroots, Inc. February 2019. R835802 (2018)
R835802C001 (2018)
not available
Presentation Kosnik MB. Concentration-response evaluation of ToxCast compounds for multivariate fingerprints of neural network function. U.S. EPA NCCT ToxCast Meeting, March 2019. R835802 (2018)
R835802 (Final)
R835802C003 (2018)
not available
Presentation Thorough QT/QTc in a dish:An in vitro human model that accurately predicts clinical concentration-QTc relationships. W. Chiu. Food and Drug Administration, Center for Drug Evaluation and Research, Pharmacology and Toxicology Reviewer Cardiac Journal Club. March 2019. R835802 (Final)
not available
Presentation Thorough QT/QTc in a dish:An in vitro human model that accurately predicts clinical concentration-QTc relationships. W. Chiu. Food and Drug Administration, Center for Drug Evaluation and Research, Pharmacology and Toxicology Reviewer Cardiac Journal Club. March 2019. R835802 (Final)
not available
Presentation Sakolish, C., Bell, C., Weber, E., Kelly, E., Himmelfarb, J., Mouneimne, R., Wade, T., Han, A., Burghardt, R., Chiu, W., and Rusyn, I. The Cross-Laboratory Testing of the Human Proximal Tubule Chip. Society of Toxicology Annual Meeting, San Antonio, TX. 2018. R835802 (Final)
not available
Presentation Burnett, S., Blanchette, A., Grimm, F., Wright, F., Chiu, W. and Rusyn, I. Enabling Assessment of Cardiotoxicity Hazard for Environmental Chemicals Using An In Vitro Human Population Model. Society of Toxicology Annual Meeting, Baltimore, MD. 2019. R835802 (Final)
not available
Presentation Reisfeld, B., Chiu, W., Hsieh, N., Ghosh, S., Olschanowsky, C., and Bois, F. POPKAT:A Framework for Bayesian Population PBPK Analysis. Society of Toxicology Annual Meeting, Baltimore, MD. 2019. R835802 (Final)
not available
Presentation Shao, K., Chiu, W.A., and Shapiro, A. The Utility of Informative Prior in Benchmark Dose Modeling for Animal Reduction. Society of Toxicology Annual Meeting, Baltimore, MD. 2019. R835802 (Final)
not available
Presentation Hsieh, N., Chiu, W., and Reisfeld, B. Pksensi:An R Package to Apply Sensitivity Analysis in Pharmacokinetic Modeling. Society of Toxicology Annual Meeting, Baltimore, MD. 2019. R835802 (Final)
R835802C001 (2018)
not available
Presentation Danforth, C., Craft, E., Bolden, A., Schultz, K., Kwiatkowski, C., Rusyn, I., and Chiu, W. Evidence integration across multiple toxicity endpoints to prioritize constituents of potential concern in oil and gas produced water. Society of Toxicology Annual Meeting, Baltimore, MD. 2019. R835802 (Final)
R835802C001 (2018)
not available
Presentation Blanchette, A., Dalaijamts, C., Grimm, F.A., Ferguson, K., Anson, B., Rusyn, I. and Chiu, W.A. An In Vitro Human Bayesian Population Pharmacodynamic Model for Predicting Effects on Heart Rhythm. Organotypic culture models annual STAR grantee meeting. Durham, NC. 2018. R835802 (Final)
not available
Presentation Burnett, S., Grimm, F., Anson, B., Wright, F.A., Chiu, W, and Rusyn, I. An in vitro human population model for assessment of inter-individual variability in cardiotoxicity. Lone Star SOT Annual Meeting, Austin, TX. 2018. R835802 (Final)
not available
Presentation Blanchette, A., Grimm, F., Dalaijamts, C., Hsieh, N.H., Ferguson, K., Luo, Y.S., Anson, B., Rusyn, I., and Chiu, W.A. Thorough QT/QTC in a dish:An in vitro human model that accurately predicts clinical concentration-QTC relationships. Lone Star SOT Annual Meeting, Austin, TX. 2018. R835802 (Final)
not available
Presentation Botta, D., Popp, J., Farris, L., Van Ness, K.P., White, C.C., Kelly, E.J., Faustman, E.M., Rusyn, I., Threadgill, D.W. and Kavanagh, T.J. Initial characterization of hepatocytes derived from Collaborative Cross recombinant inbred mouse strain iPSCs. Organotypic culture models annual STAR grantee meeting. Durham, NC. 2018. R835802 (Final)
not available
Presentation Chen, Z., Yanagisawa, L., Chiu, W.A., and Rusyn, I. A multi-tissue organotypic human in vitro model for rapid hazard identification of environmental chemicals and mixtures. The Harvey Research Symposium, Corpus Christie, TX. 2018. R835802 (Final)
not available
Presentation Chen, Z., Yanagisawa, L., Liu, Y., Camargo, K., Casillas, G., McDonald, T., Horney, J., Chiu, W.A., and Rusyn, I. A multi-tissue organotypic human in vitro model for rapid hazard identification of environmental chemicals and mixtures. Society of Toxicology Annual Meeting, Baltimore, MD. 2019. R835802 (Final)
not available
Presentation Chiu, W.A., Ouyang, O., Dalaijamts, C., Axelrad, D.A., Dockins, C., and Paoli, G. Broad Application of a Probabilistic Dose-response Framework to Improve Chemical Risk Assessment. Society of Toxicology Annual Meeting, San Antonio, TX. 2018. R835802 (Final)
not available
Presentation Grimm, F.A., Klaren, W.K., Li, X., House, J.S., Chiu, W., Lehmler, H.J., Robertson, L.W., and Rusyn, I. Cardiotoxicity Screening of Polychlorinated Biphenyls and Their Major Metabolites. Society of Toxicology Annual Meeting, San Antonio, TX. 2018. R835802 (Final)
not available
Presentation Kosnik M.B., Planchart A., Reif D.M., and Mattingly C.J. Data integration techniques to elucidate connections between environmental factors, genetic variants, and human diseases. ASHG Annual Meeting, San Diego, CA. 2018. R835802 (Final)
not available
Presentation Klaren, W.D., Grimm, F.A., Shen, H., and Rusyn, I. In vitro approaches to grouping of complex substances and UVCBs:A case study of olefin streams. Society of Toxicology Annual Meeting, San Antonio, TX. 2018. R835802 (Final)
not available
Presentation Data Handling and Integration. F.A. Wright. Concawe Cat-App Workshop, Brussels, Belgium. September 2018. R835802 (Final)
not available
Presentation Building a Bioinformatics-savvy Workforce in Environmental Sciences. F.A. Wright. Workshop on Developing a Data Science Competent EHS Workforce, NIEHS, Research Triangle Park, NC. August 2018. R835802 (Final)
not available
Presentation Data Handling and Integration. F.A. Wright. Concawe Cat-App Workshop, Brussels, Belgium. September 2018. R835802 (Final)
not available
Presentation Building a Bioinformatics-savvy Workforce in Environmental Sciences. F.A. Wright. Workshop on Developing a Data Science Competent EHS Workforce, NIEHS, Research Triangle Park, NC. August 2018. R835802 (Final)
not available
Presentation Tissue Chip Validation Center at Texas A&M University (Tex-Val Center). I. Rusyn. Keystone Symposium:Organs-and Tissues-on-Chips. Big Sky, MT. April 2018. R835802 (Final)
not available
Presentation Grouping of UVCBs using chemical-biological read-across:Case study of petroleum substances. I. Rusyn. The Toxicology Forum. Washington, DC. January 2018. R835802 (Final)
not available
Presentation Categorization of UVCBs using chemical-biological read-across. I. Rusyn. Society of Toxicology Annual Meeting. San Antonio, TX. March 2018. R835802 (Final)
not available
Presentation Grouping of UVCBs using chemical-biological read-across:Case study of petroleum substances. I. Rusyn. The Toxicology Forum. Washington, DC. January 2018. R835802 (Final)
not available
Presentation Categorization of UVCBs using chemical-biological read-across. I. Rusyn. Society of Toxicology Annual Meeting. San Antonio, TX. March 2018. R835802 (Final)
not available
Presentation Exploring the characterization of human variability with in vivo and in vitro experimental models. I. Rusyn. The University of Pennsylvania 12th Annual Center of Excellence in Environmental Toxicology (CEET) Symposium. Philadelphia, PA. June 2018. R835802 (Final)
not available
Presentation Tissue Chip Validation Center at Texas A&M University (Tex-Val Center). I. Rusyn. Keystone Symposium:Organs-and Tissues-on-Chips. Big Sky, MT. April 2018. R835802 (Final)
not available
Presentation Exploring the characterization of human variability with in vivo and in vitro experimental models. I. Rusyn. The University of Pennsylvania 12th Annual Center of Excellence in Environmental Toxicology (CEET) Symposium. Philadelphia, PA. June 2018. R835802 (Final)
not available
Presentation Multi concentration screening of ToxCast compounds for neurotoxicity using microelectrode arrays. M.B. Kosnik EPA ToxCast Meeting. RTP, NC. February 2019. R835802 (Final)
not available
Presentation Concentration-Response Evaluation of ToxCast Compounds for Multivariate Fingerprints of Neural Network Function. M.B. Kosnik. U.S. EPA NCCT ToxCast Meeting, March 2019. R835802 (Final)
not available
Presentation Kosnik. M. Planchart, A., Marvel, S., Reif, D., Mattingly, C. Integration of curated and high-throughput screening data to elucidate environmental influences on disease pathways. Organotypic culture models annual STAR grantee meeting. Durham, NC. 2018. R835802 (Final)
not available
Presentation Concentration-Response Evaluation of ToxCast Compounds for Multivariate Fingerprints of Neural Network Function. M.B. Kosnik. U.S. EPA NCCT ToxCast Meeting, March 2019. R835802 (Final)
not available
Presentation Multi concentration screening of ToxCast compounds for neurotoxicity using microelectrode arrays. M.B. Kosnik EPA ToxCast Meeting. RTP, NC. February 2019. R835802 (Final)
not available
Presentation House, J.S., Grimm, F.A., Jima, D., Rusyn, I.,Wright, F.A. High-Throughput Concentration Response Modeling in iPSC-Cardiomyocytes. Organotypic culture models annual STAR grantee meeting. Durham, NC. 2018. R835802 (Final)
R835802C001 (2018)
not available
Presentation Accurate clinical concentration-response predictions for cardiac arrhythmias using a population-based in vitro/in silico model. W. Chiu. Laboratory Animal Sciences Virtual Event. Online Conference by Labroots, Inc. February 2019. R835802 (Final)
not available
Presentation Accurate clinical concentration-response predictions for cardiac arrhythmias using a population-based in vitro/in silico model. W. Chiu. Department of Veterinary Physiology & Pharmacology Seminar. College Station, TX. February 2019. R835802 (Final)
not available
Presentation Development and Use of Quantitative Adverse Outcome Pathways:Lessons Learned from Application to Cardiotoxicity. W. Chiu. National Academies of Sciences Workshop:Strategies and Tools for Conducting Systematic Reviews of Mechanistic Data to Support Chemical Assessments. Washington, DC. December 2018. R835802 (Final)
not available
Presentation WHO/IPCS Probabilistic Approach to Improve Chemical Dose-Response Assessments. W. Chiu. Workshop on the Development of an Evidence Based Risk Assessment Framework. Ottawa, Canada. December 2018. R835802 (Final)
not available
Presentation Using ToxCast Data in Support of the Key Characteristics of Carcinogens:Opportunities and Challenges. W.A. Chiu. The Toxicology Forum. Washington, DC. January 2018. R835802 (Final)
not available
Presentation Using ToxCast Data in Support of the Key Characteristics of Carcinogens:Opportunities and Challenges. W. Chiu. California EPA Cancer and Environmental Mixtures Meeting. Oakland, CA. August 2018. R835802 (Final)
not available
Presentation Application of the WHO-IPCS Dose-response Framework to the Human Toxicity Component of Life Cycle Impact Analysis. W. Chiu. Society for Risk Analysis Annual Meeting. Arlington, VA. December 2018. R835802 (Final)
not available
Presentation Using ToxCast Data in Support of the Key Characteristics of Carcinogens:Opportunities and Challenges. W.A. Chiu. The Toxicology Forum. Washington, DC. January 2018. R835802 (Final)
not available
Presentation Probabilistic Dose-Response Assessment Using the WHO/IPCS Framework. W. Chiu. Training Workshop for California EPA/Department of Pesticide Regulation. Sacramento, CA. February 2019. R835802 (Final)
not available
Presentation Using ToxCast Data in Support of the Key Characteristics of Carcinogens:Opportunities and Challenges. W. Chiu. California EPA Cancer and Environmental Mixtures Meeting. Oakland, CA. August 2018. R835802 (Final)
not available
Presentation Application of the WHO-IPCS Dose-response Framework to the Human Toxicity Component of Life Cycle Impact Analysis. W. Chiu. Society for Risk Analysis Annual Meeting. Arlington, VA. December 2018. R835802 (Final)
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Presentation Popp, J. and Threadgill, D.W. Baseline Cardiac Phenotypes across a Diverse Population of Mice:Implications for Cardiotoxicity Risk Assessment. Society of Toxicology Annual Meeting, Baltimore, MD. 2019. R835802 (Final)
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Presentation Popp, J. and Threadgill, D.W. Linking in vitro-to-in vivo toxicity testing using genetically-matched organoids and mice from a novel genetic reference population. Organotypic culture models annual STAR grantee meeting. Durham, NC. 2018. R835802 (Final)
not available