Grantee Research Project Results
Research Centers
Johns Hopkins University
The Johns Hopkins University
More than 7 million children in the United States have asthma, a chronic disease that causes coughing, wheezing, chest tightness, and trouble breathing. The disease disproportionately affects inner-city African Americans; a disparity scientists believe is due in part to the direct and indirect effects of poverty, including high levels of pollutants and allergens in inner-city homes and neighborhoods. While such disparities in asthma health are not new, the gap has widened over the past 30 years. Research at this Center is designed to test whether eating a poor-quality diet may increase asthma severity among children and whether a high anti-oxidant, anti-inflammatory diet increases the body’s ability to respond to stressors while decreasing susceptibility to pollutant and allergen exposures.
At this center, researchers focus on children living in the inner city of Baltimore, Maryland to study how certain foods cause asthmatic responses and whether certain foods make a person’s asthma better or worse. Previous research has shown that eating a “Mediterranean diet” rich in fruits, vegetables, legumes, and low-fat dairy foods, antioxidants and vitamin D can reduce asthma attacks. On the other hand, a poor-quality diet high in fats from meat, junk food and soda may impair the body’s ability to handle pollution and allergens, potentially leading to more frequent asthma attacks.
Through its research, the center aims to better understand how dietary influences such as the “Mediterranean diet” or other dietary interventions impact asthmatic response to indoor and outdoor pollutants and triggers. The researchers hope to develop practical advice on what foods children could eat to better control their asthma.
Identifier | Abstract | Principal Investigator |
Annual/ Final Reports |
Pubs Count | Institution | Grant Representative |
Grant Amount |
Project Period |
|
---|---|---|---|---|---|---|---|---|---|
1 |
CR835785
Centers - Main center abstract - Center for Environmental Medicine, Asthma, lung biology |
Initial Annual CEMALB Progress Report: Human Health Effects of Environmental Pollutants |
Peden, David B Alexis, Neil Bennett, William D Caughey, Melissa Hernandez, Michelle L Jaspers, Ilona Noah, Terry Rebuli, Meghan E Robinette, Carole Smith, Judith - Principal Investigators listed are sub-PIs determined by the center. |
Row 1: 2015
|
Row 1 Total Pubs:
83 Row 1 Journals: 50 -- Row 1: No Books -- |
University of North Carolina at Chapel Hill | Schmitt, Michael | $9,800,000 |
April 01, 2015 - March 31, 2022 |
2 |
R826442
Centers - Main center abstract - University of Washington Center for Clean Air Research |
National Environmental Respiratory Center |
Mauderly, Joe L. Barr, E. B. Barrett, Edward G. Belinsky, Steven A. Campen, Matthew J. Gigliotti, Andrew Harrod, Kevin McDonald, Jacob D. Reed, Matthew D. Seagrave, Jean Clare Seilkop, Steven Swenberg, James A. - Principal Investigators listed are sub-PIs determined by the center. |
Lovelace Biomedical & Environmental Research Institute, University of North Carolina at Chapel Hill | Chung, Serena | $8,390,600 |
April 01, 1998 - March 31, 2003 |
||
3 |
R826724
Centers - Main center abstract - Center for the Study of Childhood Asthma in the Urban Environment |
The Johns Hopkins University Center For The Asthmatic Child in the Urban Environment |
Eggleston, Peyton A.
- Principal Investigators listed are sub-PIs determined by the center. |
The Johns Hopkins University | Callan, Richard | $3,849,556 |
August 01, 1998 - July 31, 2003 |
||
4 |
R827039
Centers - Main center abstract - Center for Research on Early Childhood Exposure and Development in Puerto Rico |
Inner City Toxicants and Neurodevelopmental Impairment |
Wolff, Mary S.
- Principal Investigators listed are sub-PIs determined by the center. |
Row 4: 2000
|
Row 4 Total Pubs:
34 Row 4 Journals: 32 -- Row 4: No Books -- |
Mount Sinai School of Medicine | Callan, Richard | $3,136,392 |
August 01, 1998 - July 31, 2003 (Extended to July 31, 2004) |
5 |
R828677
Centers - Main center abstract - Center for Integrating Statistical and Environmental Science |
Atlantic Coast Environmental Indicators Consortium |
Paerl, Hans Boicourt, William C. Field, Donald Fonseca, Mark Harding Jr., Lawrence W. Hopkinson, Charles S Houde, Edward D. Kenworthy, Judson Luettich Jr., Richard A. Morris, James T. Noble, Rachel T. Pinckney, James L. Roman, Michael R. Torres, Raymond - Principal Investigators listed are sub-PIs determined by the center. |
Row 5: 2001
|
Row 5 Total Pubs:
118 Row 5 Journals: 40 Row 5 Books: 4 |
University of North Carolina at Chapel Hill, Ecosystem Management Research Institute, National Oceanic and Atmospheric Administration, Texas A & M University, University of Maryland - College Park, University of South Carolina at Columbia | Packard, Benjamin H | $5,812,315 |
February 26, 2001 - February 25, 2005 |
6 |
R828771
Centers - Main center abstract - Center for the Study of Childhood Asthma in the Urban Environment |
Center for Hazardous Substances in Urban Environments (CHSUE) |
Bouwer, Edward J. Alavi, Hedy Baker, Joel E. Ball, William P. Carley, Robert Chen, Guangming Fairbrother, D. Howard Haag, George Helble, Joseph J. Mason, Robed Meneveau, Charles Nikolaidis, Nik O'Melia, Charles R. Oguntimein, G. B. Ondov, John M. Parlange, Marc Perkins, Chris Roberts, A. Lynn Sattler, Barbara Smets, Barth F. Stone, Alan T. Williams, Sedley - Principal Investigators listed are sub-PIs determined by the center. |
Row 6: 2002
|
Row 6 Total Pubs:
30 Row 6 Journals: 8 Row 6 Books: 1 |
The Johns Hopkins University, Morgan State University, University of Connecticut, University of Maryland - College Park | Aja, Hayley | $6,000,000 |
October 01, 2001 - September 30, 2007 |
7 |
R829482
Centers - Main center abstract - Center for the Study of Childhood Asthma in the Urban Environment |
Center for Hazardous Substances in Urban Environments (CHSUE) |
Bouwer, Edward J. Alavi, Hedy - Principal Investigators listed are sub-PIs determined by the center. |
Row 7: Final
|
The Johns Hopkins University | Aja, Hayley | $941,000 |
October 01, 2001 - September 30, 2007 |
|
8 |
R831711
Centers - Main center abstract - Center for Research on Early Childhood Exposure and Development in Puerto Rico |
Inner City Toxicants, Child Growth and Development |
Wolff, Mary S. Barr, Dana Boyd Brenner, Barbara Chen, Jia Claudio, Luz Deych, Elena Engel, Stephanie M. Galvez, Maida Godbold, James Lapinski, Robert Moshier, Erin Teitelbaum, Susan Wetmur, James G. - Principal Investigators listed are sub-PIs determined by the center. |
Row 8: 2004
|
Row 8 Total Pubs:
249 Row 8 Journals: 119 Row 8 Books: 23 |
Mount Sinai School of Medicine, Centers for Disease Control and Prevention | Callan, Richard | $4,004,980 |
November 01, 2003 - October 30, 2008 (Extended to October 30, 2010) |
9 |
R832139
Centers - Main center abstract - Center for the Study of Childhood Asthma in the Urban Environment |
Johns Hopkins Center for Childhood Asthma in the Urban Environment |
Breysse, Patrick N. Butz, Arlene Diette, Greg Georas, Steven Kanchanaraksa, Sukon Matsui, Elizabeth C. Wills-Karp, Marsha - Principal Investigators listed are sub-PIs determined by the center. |
Row 9: 2004
|
Row 9 Total Pubs:
115 Row 9 Journals: 111 Row 9 Books: 3 |
The Johns Hopkins University | Callan, Richard | $3,576,564 |
November 01, 2003 - October 31, 2008 (Extended to October 31, 2010) |
10 |
R832417
Centers - Main center abstract - Center for the Study of Childhood Asthma in the Urban Environment |
Johns Hopkins Particulate Matter Research Center |
Samet, Jonathan M. Bell, Michelle L. Breysse, Patrick N. Chillrud, Steven DeCastro, Rey Dominici, Francesca Garcia, Joe Geyh, Alison Irizarry, Rafael Natarajan, Viswanathan Ondov, John M. Peng, Roger D. Spannhake, Ernst Zeger, Scott L. - Principal Investigators listed are sub-PIs determined by the center. |
Row 10: 2006
|
Row 10 Total Pubs:
83 Row 10 Journals: 63 Row 10 Books: 2 |
The Johns Hopkins University, Lamont Doherty Earth Observatory of Columbia University, University of Chicago, University of Maryland - College Park, Yale University | Chung, Serena | $7,993,275 |
October 01, 2005 - September 30, 2010 |
11 |
R832720
Centers - Main center abstract - Center for Environmental Medicine, Asthma, lung biology |
Carolina Environmental Bioinformatics Center |
Wright, Fred A. Farber, Rosann Galluppi, Kenneth J. Hemminger, Brad Kupper, Lawrence Marron, J. Stephen McMillan, Leonard Prins, Jan F. Rusyn, Ivan Stotts, David Sym, Mary Threadgill, David W. Tropsha, Alex - Principal Investigators listed are sub-PIs determined by the center. |
Row 11: 2006
|
Row 11 Total Pubs:
113 Row 11 Journals: 41 Row 11 Books: 1 |
University of North Carolina at Chapel Hill | Hahn, Intaek | $4,494,117 |
October 01, 2005 - September 30, 2010 |
12 |
R833825
Centers - Main center abstract - UT Center for Infrastructure Modeling and Management |
Carolina Center for Computational Toxicology |
Rusyn, Ivan Elston, Timothy Gomez, Shawn Gupta, Mayetri Nobel, Andrew Sun, Wei Tropsha, Alex Wang, Simon Wright, Fred A. Yeatts, Karin B. - Principal Investigators listed are sub-PIs determined by the center. |
Row 12: 2008
|
Row 12 Total Pubs:
98 Row 12 Journals: 63 Row 12 Books: 2 |
University of North Carolina at Chapel Hill, North Carolina State University | Hahn, Intaek | $3,400,000 |
April 01, 2008 - March 31, 2012 |
13 |
R834510
Centers - Main center abstract - Center for the Study of Childhood Asthma in the Urban Environment |
Mechanisms of Asthma -- Dietary Interventions against Environmental Triggers |
Diette, Greg Anderson, Cheryl Biswal, Shyam Breysse, Patrick N. Gittelsohn, Joel Hansel, Nadia Matsui, Elizabeth C. McCormack, Meredith Peng, Roger D. Rand, Cynthia Sharma, Sangita Shreffler, Wayne G. - Principal Investigators listed are sub-PIs determined by the center. |
Row 13: 2010
|
Row 13 Total Pubs:
92 Row 13 Journals: 90 -- Row 13: No Books -- |
The Johns Hopkins University | Hahn, Intaek | $4,107,128 |
August 01, 2009 - July 31, 2015 |
14 |
R835871
Centers - Main center abstract - Solutions for Energy, AiR, Climate and Health Center (SEARCH) |
SEARCH: Solutions to Energy, AiR, Climate, and Health |
Bell, Michelle L. Anastas, Paul T. Breysse, Patrick N. Curriero, Frank Deziel, Nicole Cardello Eckelman, Matthew J. Ellis, J. Hugh Esty, Daniel C. Gentner, Drew R. Gentry, Bradford S. Gillingham, Ken Gillingham, Kenneth Hobbs, Benjamin F. Katz, Howard Kerkez, Branko Koehler, Kirsten Peccia, Jordan Peng, Roger D. Son, Jiyoung Storelvmo, Trude Streets, David G. Wara, Michael W. Weyant, John P. Zaitchik, Ben Zhang, Yang Zhang, Yawei Zimmerman, Julie B. - Principal Investigators listed are sub-PIs determined by the center. |
Row 14: 2016
|
Row 14 Total Pubs:
118 Row 14 Journals: 73 -- Row 14: No Books -- |
Yale University, Argonne National Laboratory, Centers for Disease Control and Prevention, North Carolina State University, Northeastern University, Pacific Northwest National Laboratory, Stanford University, The Johns Hopkins University, University of Chicago, University of Michigan | Callan, Richard | $9,999,990 |
October 01, 2015 - September 30, 2020 (Extended to September 30, 2022) |
15 |
R836150
Centers - Main center abstract - Comparing Urban and Rural Effects of Poverty on COPD |
Comparing Urban and Rural Effects of Poverty on COPD (CURE COPD) |
Hansel, Nadia Brigham, Emily Diette, Gregory B. Eakin, Michelle Fawzy, Ashraf Galiatsatos, Panagis Hanson, Corrine K Koehler, Kirsten Li, Ying Maier, Kurt Maisonet, Mildred Matsui, Elizabeth C. McCormack, Meredith Paulin, Laura Peng, Roger D. Putcha, Nirupama Raju, Sarath Rand, Cynthia Scheuerman, Phillip - Principal Investigators listed are sub-PIs determined by the center. |
Row 15: 2016
|
Row 15 Total Pubs:
49 Row 15 Journals: 37 -- Row 15: No Books -- |
The Johns Hopkins University, East Tennessee State University, University of Nebraska Medical Center | Callan, Richard | $1,500,000 |
July 01, 2015 - June 30, 2020 (Extended to June 30, 2022) |
16 |
R836152
Centers - Main center abstract - Center for the Study of Childhood Asthma in the Urban Environment |
Center for the Study of Childhood Asthma in the Urban Environment (CCAUE) |
Hansel, Nadia Diette, Greg Koehler, Kirsten Maisonet, Mildred McCormack, Meredith Polotsky, Seva Putcha, Nirupama - Principal Investigators listed are sub-PIs determined by the center. |
Row 16: 2016
|
Row 16 Total Pubs:
70 Row 16 Journals: 46 -- Row 16: No Books -- |
The Johns Hopkins University | Callan, Richard | $1,200,000 |
September 01, 2015 - August 31, 2019 (Extended to August 31, 2021) |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.