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Grantee Research Project Results

Research Centers
Johns Hopkins University

The Johns Hopkins University

More than 7 million children in the United States have asthma, a chronic disease that causes coughing, wheezing, chest tightness, and trouble breathing. The disease disproportionately affects inner-city African Americans; a disparity scientists believe is due in part to the direct and indirect effects of poverty, including high levels of pollutants and allergens in inner-city homes and neighborhoods. While such disparities in asthma health are not new, the gap has widened over the past 30 years. Research at this Center is designed to test whether eating a poor-quality diet may increase asthma severity among children and whether a high anti-oxidant, anti-inflammatory diet increases the body’s ability to respond to stressors while decreasing susceptibility to pollutant and allergen exposures.

At this center, researchers focus on children living in the inner city of Baltimore, Maryland to study how certain foods cause asthmatic responses and whether certain foods make a person’s asthma better or worse. Previous research has shown that eating a “Mediterranean diet” rich in fruits, vegetables, legumes, and low-fat dairy foods, antioxidants and vitamin D can reduce asthma attacks. On the other hand, a poor-quality diet high in fats from meat, junk food and soda may impair the body’s ability to handle pollution and allergens, potentially leading to more frequent asthma attacks.

Through its research, the center aims to better understand how dietary influences such as the “Mediterranean diet” or other dietary interventions impact asthmatic response to indoor and outdoor pollutants and triggers. The researchers hope to develop practical advice on what foods children could eat to better control their asthma.

View Projects in List Format

  Identifier Abstract Principal
Investigator
Annual/
Final
Reports
Pubs Count Institution Grant
Representative
Grant
Amount
Project
Period
1 CR835785
Centers




- Main center abstract - Center for Environmental Medicine, Asthma, lung biology
Initial Annual CEMALB Progress Report: Human Health Effects of Environmental Pollutants Peden, David B
Alexis, Neil
Bennett, William D
Caughey, Melissa
Hernandez, Michelle L
Jaspers, Ilona
Noah, Terry
Rebuli, Meghan E
Robinette, Carole
Smith, Judith

- Principal Investigators listed are
sub-PIs determined by the center.
 
Row 1: 2015

Row 1: 2016

Row 1: 2017

Row 1: 2018

Row 1: 2019

Row 1: 2020

Row 1: Final

Row 1 Total Pubs: 83
Row 1 Journals: 50
-- Row 1: No Books --
 
University of North Carolina at Chapel Hill Schmitt, Michael   $9,800,000   April 01, 2015 -
March 31, 2022  
2 R826442
Centers




- Main center abstract - University of Washington Center for Clean Air Research
National Environmental Respiratory Center Mauderly, Joe L.
Barr, E. B.
Barrett, Edward G.
Belinsky, Steven A.
Campen, Matthew J.
Gigliotti, Andrew
Harrod, Kevin
McDonald, Jacob D.
Reed, Matthew D.
Seagrave, Jean Clare
Seilkop, Steven
Swenberg, James A.

- Principal Investigators listed are
sub-PIs determined by the center.
 
  Lovelace Biomedical & Environmental Research Institute, University of North Carolina at Chapel Hill Chung, Serena   $8,390,600   April 01, 1998 -
March 31, 2003  
3 R826724
Centers




- Main center abstract - Center for the Study of Childhood Asthma in the Urban Environment
The Johns Hopkins University Center For The Asthmatic Child in the Urban Environment Eggleston, Peyton A.

- Principal Investigators listed are
sub-PIs determined by the center.
 
  The Johns Hopkins University Callan, Richard   $3,849,556   August 01, 1998 -
July 31, 2003  
4 R827039
Centers




- Main center abstract - Center for Research on Early Childhood Exposure and Development in Puerto Rico
Inner City Toxicants and Neurodevelopmental Impairment Wolff, Mary S.

- Principal Investigators listed are
sub-PIs determined by the center.
 
Row 4: 2000

Row 4: 2002

Row 4 Total Pubs: 34
Row 4 Journals: 32
-- Row 4: No Books --
 
Mount Sinai School of Medicine Callan, Richard   $3,136,392   August 01, 1998 -
July 31, 2003
(Extended to July 31, 2004)  
5 R828677
Centers




- Main center abstract - Center for Integrating Statistical and Environmental Science
Atlantic Coast Environmental Indicators Consortium Paerl, Hans
Boicourt, William C.
Field, Donald
Fonseca, Mark
Harding Jr., Lawrence W.
Hopkinson, Charles S
Houde, Edward D.
Kenworthy, Judson
Luettich Jr., Richard A.
Morris, James T.
Noble, Rachel T.
Pinckney, James L.
Roman, Michael R.
Torres, Raymond

- Principal Investigators listed are
sub-PIs determined by the center.
 
Row 5: 2001

Row 5: 2002

Row 5: 2003

Row 5: 2004

Row 5: Final

Row 5 Total Pubs: 118
Row 5 Journals: 40
Row 5 Books: 4
 
University of North Carolina at Chapel Hill, Ecosystem Management Research Institute, National Oceanic and Atmospheric Administration, Texas A & M University, University of Maryland - College Park, University of South Carolina at Columbia Packard, Benjamin H   $5,812,315   February 26, 2001 -
February 25, 2005  
6 R828771
Centers




- Main center abstract - Center for the Study of Childhood Asthma in the Urban Environment
Center for Hazardous Substances in Urban Environments (CHSUE) Bouwer, Edward J.
Alavi, Hedy
Baker, Joel E.
Ball, William P.
Carley, Robert
Chen, Guangming
Fairbrother, D. Howard
Haag, George
Helble, Joseph J.
Mason, Robed
Meneveau, Charles
Nikolaidis, Nik
O'Melia, Charles R.
Oguntimein, G. B.
Ondov, John M.
Parlange, Marc
Perkins, Chris
Roberts, A. Lynn
Sattler, Barbara
Smets, Barth F.
Stone, Alan T.
Williams, Sedley

- Principal Investigators listed are
sub-PIs determined by the center.
 
Row 6: 2002

Row 6: 2003

Row 6: 2004

Row 6: 2005

Row 6: Final

Row 6 Total Pubs: 30
Row 6 Journals: 8
Row 6 Books: 1
 
The Johns Hopkins University, Morgan State University, University of Connecticut, University of Maryland - College Park Aja, Hayley   $6,000,000   October 01, 2001 -
September 30, 2007  
7 R829482
Centers




- Main center abstract - Center for the Study of Childhood Asthma in the Urban Environment
Center for Hazardous Substances in Urban Environments (CHSUE) Bouwer, Edward J.
Alavi, Hedy

- Principal Investigators listed are
sub-PIs determined by the center.
 
Row 7: Final

  The Johns Hopkins University Aja, Hayley   $941,000   October 01, 2001 -
September 30, 2007  
8 R831711
Centers




- Main center abstract - Center for Research on Early Childhood Exposure and Development in Puerto Rico
Inner City Toxicants, Child Growth and Development Wolff, Mary S.
Barr, Dana Boyd
Brenner, Barbara
Chen, Jia
Claudio, Luz
Deych, Elena
Engel, Stephanie M.
Galvez, Maida
Godbold, James
Lapinski, Robert
Moshier, Erin
Teitelbaum, Susan
Wetmur, James G.

- Principal Investigators listed are
sub-PIs determined by the center.
 
Row 8: 2004

Row 8: 2005

Row 8: 2006

Row 8: 2007

Row 8: Final

Row 8 Total Pubs: 249
Row 8 Journals: 119
Row 8 Books: 23
 
Mount Sinai School of Medicine, Centers for Disease Control and Prevention Callan, Richard   $4,004,980   November 01, 2003 -
October 30, 2008
(Extended to October 30, 2010)  
9 R832139
Centers




- Main center abstract - Center for the Study of Childhood Asthma in the Urban Environment
Johns Hopkins Center for Childhood Asthma in the Urban Environment Breysse, Patrick N.
Butz, Arlene
Diette, Greg
Georas, Steven
Kanchanaraksa, Sukon
Matsui, Elizabeth C.
Wills-Karp, Marsha

- Principal Investigators listed are
sub-PIs determined by the center.
 
Row 9: 2004

Row 9: 2005

Row 9: 2006

Row 9: 2007

Row 9: Final

Row 9 Total Pubs: 115
Row 9 Journals: 111
Row 9 Books: 3
 
The Johns Hopkins University Callan, Richard   $3,576,564   November 01, 2003 -
October 31, 2008
(Extended to October 31, 2010)  
10 R832417
Centers




- Main center abstract - Center for the Study of Childhood Asthma in the Urban Environment
Johns Hopkins Particulate Matter Research Center Samet, Jonathan M.
Bell, Michelle L.
Breysse, Patrick N.
Chillrud, Steven
DeCastro, Rey
Dominici, Francesca
Garcia, Joe
Geyh, Alison
Irizarry, Rafael
Natarajan, Viswanathan
Ondov, John M.
Peng, Roger D.
Spannhake, Ernst
Zeger, Scott L.

- Principal Investigators listed are
sub-PIs determined by the center.
 
Row 10: 2006

Row 10: 2007

Row 10: 2008

Row 10: 2009

Row 10: Final

Row 10 Total Pubs: 83
Row 10 Journals: 63
Row 10 Books: 2
 
The Johns Hopkins University, Lamont Doherty Earth Observatory of Columbia University, University of Chicago, University of Maryland - College Park, Yale University Chung, Serena   $7,993,275   October 01, 2005 -
September 30, 2010  
11 R832720
Centers




- Main center abstract - Center for Environmental Medicine, Asthma, lung biology
Carolina Environmental Bioinformatics Center Wright, Fred A.
Farber, Rosann
Galluppi, Kenneth J.
Hemminger, Brad
Kupper, Lawrence
Marron, J. Stephen
McMillan, Leonard
Prins, Jan F.
Rusyn, Ivan
Stotts, David
Sym, Mary
Threadgill, David W.
Tropsha, Alex

- Principal Investigators listed are
sub-PIs determined by the center.
 
Row 11: 2006

Row 11: 2007

Row 11: 2008

Row 11: 2009

Row 11 Total Pubs: 113
Row 11 Journals: 41
Row 11 Books: 1
 
University of North Carolina at Chapel Hill Hahn, Intaek   $4,494,117   October 01, 2005 -
September 30, 2010  
12 R833825
Centers




- Main center abstract - UT Center for Infrastructure Modeling and Management
Carolina Center for Computational Toxicology Rusyn, Ivan
Elston, Timothy
Gomez, Shawn
Gupta, Mayetri
Nobel, Andrew
Sun, Wei
Tropsha, Alex
Wang, Simon
Wright, Fred A.
Yeatts, Karin B.

- Principal Investigators listed are
sub-PIs determined by the center.
 
Row 12: 2008

Row 12: Final

Row 12 Total Pubs: 98
Row 12 Journals: 63
Row 12 Books: 2
 
University of North Carolina at Chapel Hill, North Carolina State University Hahn, Intaek   $3,400,000   April 01, 2008 -
March 31, 2012  
13 R834510
Centers




- Main center abstract - Center for the Study of Childhood Asthma in the Urban Environment
Mechanisms of Asthma -- Dietary Interventions against Environmental Triggers Diette, Greg
Anderson, Cheryl
Biswal, Shyam
Breysse, Patrick N.
Gittelsohn, Joel
Hansel, Nadia
Matsui, Elizabeth C.
McCormack, Meredith
Peng, Roger D.
Rand, Cynthia
Sharma, Sangita
Shreffler, Wayne G.

- Principal Investigators listed are
sub-PIs determined by the center.
 
Row 13: 2010

Row 13: 2011

Row 13: 2012

Row 13: 2013

Row 13: 2014

Row 13: Final

Row 13 Total Pubs: 92
Row 13 Journals: 90
-- Row 13: No Books --
 
The Johns Hopkins University Hahn, Intaek   $4,107,128   August 01, 2009 -
July 31, 2015  
14 R835871
Centers




- Main center abstract - Solutions for Energy, AiR, Climate and Health Center (SEARCH)
SEARCH: Solutions to Energy, AiR, Climate, and Health Bell, Michelle L.
Anastas, Paul T.
Breysse, Patrick N.
Curriero, Frank
Deziel, Nicole Cardello
Eckelman, Matthew J.
Ellis, J. Hugh
Esty, Daniel C.
Gentner, Drew R.
Gentry, Bradford S.
Gillingham, Ken
Gillingham, Kenneth
Hobbs, Benjamin F.
Katz, Howard
Kerkez, Branko
Koehler, Kirsten
Peccia, Jordan
Peng, Roger D.
Son, Jiyoung
Storelvmo, Trude
Streets, David G.
Wara, Michael W.
Weyant, John P.
Zaitchik, Ben
Zhang, Yang
Zhang, Yawei
Zimmerman, Julie B.

- Principal Investigators listed are
sub-PIs determined by the center.
 
Row 14: 2016

Row 14: 2017

Row 14: 2018

Row 14: 2019

Row 14: 2020

Row 14: 2021

Row 14: Final

Row 14 Total Pubs: 118
Row 14 Journals: 73
-- Row 14: No Books --
 
Yale University, Argonne National Laboratory, Centers for Disease Control and Prevention, North Carolina State University, Northeastern University, Pacific Northwest National Laboratory, Stanford University, The Johns Hopkins University, University of Chicago, University of Michigan Callan, Richard   $9,999,990   October 01, 2015 -
September 30, 2020
(Extended to September 30, 2022)  
15 R836150
Centers




- Main center abstract - Comparing Urban and Rural Effects of Poverty on COPD
Comparing Urban and Rural Effects of Poverty on COPD (CURE COPD) Hansel, Nadia
Brigham, Emily
Diette, Gregory B.
Eakin, Michelle
Fawzy, Ashraf
Galiatsatos, Panagis
Hanson, Corrine K
Koehler, Kirsten
Li, Ying
Maier, Kurt
Maisonet, Mildred
Matsui, Elizabeth C.
McCormack, Meredith
Paulin, Laura
Peng, Roger D.
Putcha, Nirupama
Raju, Sarath
Rand, Cynthia
Scheuerman, Phillip

- Principal Investigators listed are
sub-PIs determined by the center.
 
Row 15: 2016

Row 15: 2017

Row 15: 2018

Row 15: 2019

Row 15: 2020

Row 15: 2021

Row 15: Final

Row 15 Total Pubs: 49
Row 15 Journals: 37
-- Row 15: No Books --
 
The Johns Hopkins University, East Tennessee State University, University of Nebraska Medical Center Callan, Richard   $1,500,000   July 01, 2015 -
June 30, 2020
(Extended to June 30, 2022)  
16 R836152
Centers




- Main center abstract - Center for the Study of Childhood Asthma in the Urban Environment
Center for the Study of Childhood Asthma in the Urban Environment (CCAUE) Hansel, Nadia
Diette, Greg
Koehler, Kirsten
Maisonet, Mildred
McCormack, Meredith
Polotsky, Seva
Putcha, Nirupama

- Principal Investigators listed are
sub-PIs determined by the center.
 
Row 16: 2016

Row 16: 2017

Row 16: 2018

Row 16: 2019

Row 16: 2020

Row 16: Final

Row 16 Total Pubs: 70
Row 16 Journals: 46
-- Row 16: No Books --
 
The Johns Hopkins University Callan, Richard   $1,200,000   September 01, 2015 -
August 31, 2019
(Extended to August 31, 2021)  

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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