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Grantee Research Project Results

Research Centers
Johns Hopkins University

The Johns Hopkins University

More than 7 million children in the United States have asthma, a chronic disease that causes coughing, wheezing, chest tightness, and trouble breathing. The disease disproportionately affects inner-city African Americans; a disparity scientists believe is due in part to the direct and indirect effects of poverty, including high levels of pollutants and allergens in inner-city homes and neighborhoods. While such disparities in asthma health are not new, the gap has widened over the past 30 years. Research at this Center is designed to test whether eating a poor-quality diet may increase asthma severity among children and whether a high anti-oxidant, anti-inflammatory diet increases the body’s ability to respond to stressors while decreasing susceptibility to pollutant and allergen exposures.

At this center, researchers focus on children living in the inner city of Baltimore, Maryland to study how certain foods cause asthmatic responses and whether certain foods make a person’s asthma better or worse. Previous research has shown that eating a “Mediterranean diet” rich in fruits, vegetables, legumes, and low-fat dairy foods, antioxidants and vitamin D can reduce asthma attacks. On the other hand, a poor-quality diet high in fats from meat, junk food and soda may impair the body’s ability to handle pollution and allergens, potentially leading to more frequent asthma attacks.

Through its research, the center aims to better understand how dietary influences such as the “Mediterranean diet” or other dietary interventions impact asthmatic response to indoor and outdoor pollutants and triggers. The researchers hope to develop practical advice on what foods children could eat to better control their asthma.

View Projects in Tabular Format

Main Center Abstract and Reports:

Atlantic Coast Environmental Indicators Consortium
  • Original Abstract
  • 2001 Progress Report
  • 2002 Progress Report
  • 2003 Progress Report
  • 2004 Progress Report
  • Final Report
Center for Hazardous Substances in Urban Environments (CHSUE)
  • Original Abstract
  • 2002 Progress Report
  • 2003 Progress Report
  • 2004 Progress Report
  • 2005 Progress Report
  • Final Report
The Johns Hopkins University Center For The Asthmatic Child in the Urban Environment
  • Original Abstract
Inner City Toxicants and Neurodevelopmental Impairment
  • Original Abstract
  • 2000 Progress Report
  • 2002 Progress Report
Center for Hazardous Substances in Urban Environments (CHSUE)
  • Original Abstract
  • Final Report
Carolina Environmental Bioinformatics Center
  • Original Abstract
  • 2006 Progress Report
  • 2007 Progress Report
  • 2008 Progress Report
  • 2009 Progress Report
Johns Hopkins Particulate Matter Research Center
  • Original Abstract
  • 2006 Progress Report
  • 2007 Progress Report
  • 2008 Progress Report
  • 2009 Progress Report
  • Final Report
Inner City Toxicants, Child Growth and Development
  • Original Abstract
  • 2004 Progress Report
  • 2005 Progress Report
  • 2006 Progress Report
  • 2007 Progress Report
  • Final Report
Johns Hopkins Center for Childhood Asthma in the Urban Environment
  • Original Abstract
  • 2004 Progress Report
  • 2005 Progress Report
  • 2006 Progress Report
  • 2007 Progress Report
  • Final Report
Carolina Center for Computational Toxicology
  • Original Abstract
  • 2008 Progress Report
  • Final Report
Mechanisms of Asthma -- Dietary Interventions against Environmental Triggers
  • Original Abstract
  • 2010 Progress Report
  • 2011 Progress Report
  • 2012 Progress Report
  • 2013 Progress Report
  • 2014 Progress Report
  • Final Report
National Environmental Respiratory Center
  • Original Abstract
SEARCH: Solutions to Energy, AiR, Climate, and Health
  • Original Abstract
  • 2016 Progress Report
  • 2017 Progress Report
  • 2018 Progress Report
  • 2019 Progress Report
  • 2020 Progress Report
  • 2021 Progress Report
  • Final Report
Comparing Urban and Rural Effects of Poverty on COPD (CURE COPD)
  • Original Abstract
  • 2016 Progress Report
  • 2017 Progress Report
  • 2018 Progress Report
  • 2019 Progress Report
  • 2020 Progress Report
  • 2021 Progress Report
  • Final Report
Center for the Study of Childhood Asthma in the Urban Environment (CCAUE)
  • Original Abstract
  • 2016 Progress Report
  • 2017 Progress Report
  • 2018 Progress Report
  • 2019 Progress Report
  • 2020 Progress Report
  • Final Report
Initial Annual CEMALB Progress Report: Human Health Effects of Environmental Pollutants
  • Original Abstract
  • 2015 Progress Report
  • 2016 Progress Report
  • 2017 Progress Report
  • 2018 Progress Report
  • 2019 Progress Report
  • 2020 Progress Report
  • Final Report

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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Last updated April 28, 2023
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