Grantee Research Project Results
Centers of Excellence in Children's Environmental Health and Disease Prevention Research
EPA Grant Number: R827027Center: Water Environment and Reuse Foundation's National Center for Resource Recovery and Nutrient Management
Center Director: Olabode, Lola
Title: Centers of Excellence in Children's Environmental Health and Disease Prevention Research
Investigators: Perera, Frederica P.
Institution: Columbia University in the City of New York
EPA Project Officer: Callan, Richard
Project Period: August 1, 1998 through July 31, 2003 (Extended to October 31, 2004)
Project Amount: $3,136,357
RFA: Centers for Children's Environmental Health and Disease Prevention Research (1998) RFA Text | Recipients Lists
Research Category: Children's Health , Human Health
Objective:
The mission of the Columbia Center for Children's Environmental Health (CCCEH) is to undertake a comprehensive community-based assessment of environmental risks to infants and children, and to develop strategies for reducing, and ultimately preventing, those risks. The Center is responsive to the urgent health needs of the minority communities in Northern Manhattan and the South Bronx, which suffer uniquely high rates of asthma, adverse birth outcomes, impaired development, and other diseases. These communities also have disproportionately heavy exposure to environmental pollutants, which may contribute to these adverse health outcomes. Community participation is an integral component of both the Center's organizational structure and its research projects. We anticipate that research results will aid the development of community-based strategies to reduce and ultimately prevent asthma and developmental impairment in the target population, and will have implications for the control of these health risks in other inner-city, minority communities. Thus, the Center is responsive to the need for environmental justice. The Center utilizes an innovative approach -molecular epidemiology - to answer questions regarding environmental impacts on children's health. Biomarkers will be used in conjunction with questionnaires, individual exposure assessment, clinical evaluations, and quantitative measures of community-level risk factors to evaluate exposure, susceptibility, and risk from the environmental toxicants of concern, and to monitor the efficacy of intervention. The main hypotheses of the Center are that: 1) prenatal and postnatal environmental exposures to airborne particulate matter (PM), polycyclic aromatic hydrocarbons (PAH), environmental tobacco smoke (ETS), and home allergens (cockroach, house dust mite and rodent) increase the risk of asthma and/or developmental impairment in these disadvantaged communities; 2) inadequate nutritional status exacerbates the impact of these environmental toxicants; and 3) a community-based intervention to reduce these toxic exposures and improve nutritional status can reduce the risk of disease. To test these hypotheses and meet its objective, the Center is undertaking three interrelated research studies, all of which build on a prospective cohort of 400 African American and Dominican mothers and their newborn infants living in Washington Heights, Harlem and the South Bronx. The research studies (described in detail below) include projects that investigate the impact of environmental pollutants and allergens on: 1) growth and development; and 2) asthma. The third research study investigates the impact of community and home-based interventions to reduce toxicant and allergen exposure, as well as risk of asthma.Journal Articles: 74 Displayed | Download in RIS Format
| Other center views: | All 93 publications | 74 publications in selected types | All 74 journal articles |
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Balaian A, Liu X, Herbstman J, Daniela S, Whyatt R, Rauh V, Calafat A, Wapner R, Factor-Litvak P. Prenatal exposure to organophosphate and pyrethroid insecticides and the herbicide 2,4-dichlorophenoxyacetic acid and size at birth in urban pregnant women. Environmental Research 2021;201. |
R827027 (2002) R832141 (Final) |
Exit Exit |
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Barr DB, Barr JR, Maggio VL, Whitehead RD Jr., Sadowski MA, Whyatt RM, Needham LL. A multi-analyte method for the quantification of contemporary pesticides in human serum and plasma using high resolution mass spectrometry. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2002;778(1-2):99-111. |
R827027 (2002) |
Exit Exit |
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Bocskay KA, Tang D, Orjuela MA, Liu X, Warburton DP, Perera FP. Chromosomal aberrations in cord blood are associated with prenatal exposure to carcinogenic polycyclic aromatic hydrocarbons. Cancer Epidemiology, Biomarkers & Prevention 2005;14(2):506-511. |
R827027 (2002) R832141 (2006) R832141 (2007) R832141 (Final) R832141C001 (2005) |
Exit Exit |
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Bradman A, Whyatt RM. Characterizing exposures to nonpersistent pesticides during pregnancy and early childhood in the National Children's Study: a review of monitoring and measurement methodologies. Environmental Health Perspectives 2005;113(8):1092-1099. |
R827027 (2002) R831710 (2004) R831710 (2005) R831710 (Final) R832141 (2006) R832141 (2007) R832141 (Final) |
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Carlton EJ, Moats HL, Feinberg M, Shepard P, Garfinkel R, Whyatt R, Evans D. Pesticide sales in low-income, minority neighborhoods. Journal of Community Health 2004;29(3):231-244. |
R827027 (2002) R832141 (2005) R832141 (2006) R832141 (2007) R832141 (Final) |
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Chew GL, Perzanowski MS, Miller RL, Correa JC, Hoepner LA, Jusino CM, Becker MG, Kinney PL. Distribution and determinants of mouse allergen exposure in low-income New York City apartments. Environmental Health Perspectives 2003;111(10):1348-1351. |
R827027 (2002) R832141 (2005) R832141 (2006) R832141 (2007) |
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Choi H, Perera F, Pac A, Wang L, Flak E, Mroz E, Jacek R, Chai-Onn T, Jedrychowski W, Masters E, Camann D, Spengler J. Estimating Individual-Level Exposure to Airborne Polycyclic Aromatic Hydrocarbons throughout the Gestational Period Based on Personal, Indoor, and Outdoor Monitoring. JOURNAL OF URBAN HEALTH-BULLETIN OF THE NEW YORK ACADEMY OF MEDICINE 2011;88(3):454-468. |
R827027 (2002) R832141 (Final) |
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Choi H, Wang L, Lin X, Spengler JD, Perera FP. Fetal window of vulnerability to airborne polycyclic aromatic hydrocarbons on proportional intrauterine growth restriction. PLoS One 2012;7(4):e35464 (11 pp.). |
R827027 (2002) R832141 (Final) R834509 (2013) R834509 (2014) R834509 (Final) R834509C002 (Final) |
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Choi H, Perera FP. Sources of greater fetal vulnerability to airborne polycyclic aromatic hydrocarbons among African Americans. Journal of Epidemiology and Community Health 2012;66(2):121-126. |
R827027 (2002) R832141 (Final) R834509 (2013) R834509 (2014) R834509 (Final) R834509C002 (Final) |
Exit Exit |
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Choi H, Spengler J. Source attribution of personal exposure to airborne polycyclic aromatic hydrocarbon mixture using concurrent personal, indoor, and outdoor measurements. ENVIRONMENT INTERNATIONAL 2014;63:173-181. |
R827027 (2002) R828609 (Final) R832141 (Final) |
Exit Exit |
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Choi H, Melly S, Spengler J. Intraurban and Longitudinal Variability of Classical Pollutants in Krakow, Poland, 2000-2010. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH 2015;12(5):4967-4991. |
R827027 (2002) R832141 (Final) |
Exit Exit |
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Choi H, Zdeb M, Perera F, Spengler J. Estimation of chronic personal exposure to airborne polycyclic aromatic hydrocarbons. SCIENCE OF THE TOTAL ENVIRONMENT 2015;527:252-261. |
R827027 (2002) R828609 (Final) R832141 (Final) |
Exit Exit |
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Chow JC, Watson JG, Chen L-WA, Ho SSH, Koracin D, Zielinska B, Tang D, Perera F, Cao J, Lee SC. Exposure to PM2.5 and PAHs from the Tong Liang, China epidemiological study. Journal of Environmental Science and Health Part A, Toxic/Hazardous Substances and Environmental Engineering 2006;41(4):517-542. |
R827027 (2002) R832141 (2007) |
Exit Exit |
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Dietrich KN, Eskenazi B, Schantz S, Yolton K, Rauh VA, Johnson CB, Alkon A, Canfield RL, Pessah IN, Berman RF. Principles and practices of neurodevelopmental assessment in children: lessons learned from the Centers for Children's Environmental Health and Disease Prevention Research. Environmental Health Perspectives 2005;113(10):1437-1446. |
R827027 (2002) R829388 (2006) R829388 (Final) R829388C006 (2005) R829389 (2005) R829389 (Final) R829390 (2005) R829390 (Final) R829390C002 (2005) R831710 (2005) R831710 (Final) R831711 (2005) R832141 (2006) R832141 (2007) R832141 (Final) |
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Durham T, Guo J, Cowell W, Riley K, Wang S, Tang D, Perera F, Herbstman J. Prenatal PM2.5 Exposure in Relation to Maternal and Newborn Telomere Length at Delivery. Toxics 23;10(1):13. |
R827027 (2002) R832141 (Final) R834509 (Final) R836154 (Final) |
Exit Exit |
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Eggleston PA, Diette G, Lipsett M, Lewis T, Tager I, McConnell R, Chrischilles E, Lanphear B, Miller R, Krishnan J. Lessons learned for the study of childhood asthma from the Centers for Children’s Environmental Health and Disease Prevention Research. Environmental Health Perspectives 2005;113(10):1430-1436. |
R827027 (2002) R826710 (Final) R829389 (2003) R829389 (2004) R829389 (2005) R829389 (Final) R831710 (2004) R831710 (2005) R831710 (Final) R831861 (2005) R831861 (2006) R831861C001 (2006) R832139 (2004) R832139 (2005) R832139 (2006) R832139C002 (2005) R832139C003 (2005) R832141 (2006) R832141 (2007) R832141 (Final) |
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Engel S, Bradman A, Wolf M, Rauh V. Prenatal Organophosphor Pesticide Exposure and Child Neurodevelopment at 24 Months:An Analysis of Four Birth Cohorts. ENVIRONMENTAL HEALTH PERSPECTIVES 2016;124(6):822-830. |
R827027 (2002) R826709 (2002) R826886 (2000) R827039 (2002) R828609 (Final) R832141 (Final) |
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Eskenazi B, Gladstone EA, Berkowitz GS, Drew CH, Faustman EM, Holland NT, Lanphear B, Meisel SJ, Perera FP, Rauh VA, Sweeney A, Whyatt RM, Yolton K. Methodologic and logistic issues in conducting longitudinal birth cohort studies: lessons learned from the Centers for Children's Environmental Health and Disease Prevention Research. Environmental Health Perspectives 2005;113(10):1419-1429. |
R827027 (2002) R829389 (2003) R829389 (2004) R829389 (2005) R829389 (Final) R829390 (2005) R829390 (Final) R829390C002 (2005) R831709 (2005) R831709 (Final) R831709C001 (2004) R831710 (2005) R831710 (Final) R831710C001 (2006) R831710C002 (2006) R831711 (2005) R831711 (2006) R831711 (2007) R831711 (Final) R831711C001 (2006) R831711C002 (2004) R831711C002 (2006) R831711C003 (2006) R832141 (2005) R832141 (2007) R832141 (Final) |
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Evans DT, Fullilove MT, Green L, Levison M. Awareness of environmental risks and protective actions among minority women in Northern Manhattan. Environmental Health Perspectives 2002;110(S2):271-275. |
R827027 (2002) |
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Fenske RA, Bradman A, Whyatt RM, Wolff MS, Barr DB. Lessons learned for the assessment of children's pesticide exposure: critical sampling and analytical issues for future studies. Environmental Health Perspectives 2005;113(10):1455-1462. |
R827027 (2002) R831709 (2005) R831709 (2007) R831709 (Final) R831710 (2004) R831710 (2005) R831710 (Final) R831711 (2004) R831711 (2005) R831711 (2006) R831711 (2007) R831711 (Final) R831711C001 (2006) R831711C002 (2006) R831711C003 (2006) R832141 (2006) R832141 (2007) R832141 (Final) |
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Fullilove MT. Links between the social and physical environments. Pediatric Clinics of North America, Review 2001;48(5):1253-1266. |
R827027 (2002) |
Exit |
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Gilliland F, Avol E, Kinney P, Jerrett M, Dvonch T, Lurmann F, Buckley T, Breysse P, Keeler G, de Villiers T, McConnell R. Air pollution exposure assessment for epidemiologic studies of pregnant women and children: lessons learned from the Centers for Children's Environmental Health and Disease Prevention Research. Environmental Health Perspectives 2005;113(10):1447-1454. |
R827027 (2002) R826708 (2000) R826708 (2001) R826708 (2002) R826708 (Final) R826710 (Final) R831845 (2005) R831861 (2004) R831861 (2005) R831861 (2006) R831861 (Final) R831861C001 (2006) R831861C001 (Final) R831861C002 (Final) R831861C003 (2006) R831861C003 (Final) R832139 (2006) R832141 (2006) R832141 (2007) R832141 (Final) |
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Goldstein IF, Perzanowski MS, Lendor C, Garfinkel RS, Hoepner LA, Chew GL, Perera FP, Miller RL. Prevalence of allergy symptoms and total IgE in a New York City cohort and their association with birth order. International Archives of Allergy and Immunology 2005;137(3):249-257. |
R827027 (2002) R832141 (2006) R832141 (2007) R832141 (Final) R832141C002 (2005) |
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Green L, Fullilove M, Evans D, Shepard P. “Hey, Mom, thanks!”: use of focus groups in the development of place-specific materials for a community environmental action campaign. Environmental Health Perspectives 2002;110(Suppl 2):265-269. |
R827027 (2002) R832141 (2007) |
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Hallmark B, Weginenka G, Havstad S, Billheimer D, Ownby D, Mendonca E, Gress L, Stern D, Myers J, Hershey G, Hoepner L. Chromosome 17q12-21 Variants Are Associated with Multiple Wheezing Phenotypes in Childhood. American Journal of Respiratory and Critical Care Medicine 2020;1(203):864-870. |
R827027 (2002) |
Exit Exit Exit |
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Harley KG, Engel SM, Vedar MG, Eskenazi B, Whyatt RM, Lanphear BP, Bradman A, Rauh VA, Yolton K, Hornung RW, Wetmur JG, Chen J, Holland NT, Barr DB, Perera FP, Wolff MS. Prenatal exposure to organophosphorous pesticides and fetal growth: pooled results from four longitudinal birth cohort studies. Environmental Health Perspectives 2016;124(7):1084-1092. |
R827027 (2002) R826709 (2002) R826886 (2000) R827039 (2002) R828609 (Final) R831710 (Final) R832141 (Final) R834513C001 (2015) |
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Johnson C, Havstad S, Ownby D, Joseph C, Sitarik A, Myers J, Gebretsadik T, Hartert T, Hershey G, Jackson D. Pediatric asthma incidence rates in the United States from 1980 to 2017. Journal of Allergy and Clinical Immunology 2021;148(5):1270-1280. |
R827027 (2002) |
Exit Exit |
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Kass D, McKelvey W, Carlton E, Hernandez M, Chew G, Nagle S, Garfinkel R, Clarke B, Tiven J, Espino C, Evans D. Effectiveness of an integrated pest management intervention in controlling cockroaches, mice, and allergens in New York City public housing. Environmental Health Perspectives 2009;117(8):1219-1225. |
R827027 (2002) R832141 (2007) R832141 (Final) |
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Kinney PL, Northridge ME, Correa JC, Gronning E, Joseph E, Prakash S, Goldstein I. On the front lines: an environmental asthma intervention in New York City. American Journal of Public Health 2002;92(1):24-26. |
R827027 (2002) |
Exit Exit |
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Lendor C, Johnson A, Perzanowski M, Chew GL, Goldstein IF, Kelvin E, Perera F, Miller RL. Effects of winter birth season and prenatal cockroach and mouse allergen exposure on indoor allergen-specific cord blood mononuclear cell proliferation and cytokine production. Annals of Allergy, Asthma and Immunology 2008;101(2):193-199. |
R827027 (2002) R832141 (2007) R832141 (Final) |
Exit Exit |
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Lovasi GS, Quinn JW, Rauh VA, Perera FP, Andrews HF, Garfinkel R, Hoepner L, Whyatt R, Rundle A. Chlorpyrifos exposure and urban residential environment characteristics as determinants of early childhood neurodevelopment. American Journal of Public Health 2011;101(1):63-70. |
R827027 (2002) R832141 (Final) R834509 (2011) R834509 (Final) |
Exit Exit |
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Lovasi GS, O’Neil-Dunne JPM, Lu JWT, Sheehan D, Perzanowski MS, MacFaden SW, King KL, Matte T, Miller RL, Hoepner LA, Perera FP, Rundle A. Urban tree canopy and asthma, wheeze, rhinitis, and allergic sensitization to tree pollen in a New York City birth cohort. Environmental Health Perspectives 2013;121(4):494-500. |
R827027 (2002) R832141 (Final) R834509 (Final) |
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Margolis A, Ramphal B, Pagliaccio D, Banker S, Selmanovic E, Thomas L, Factor-Litvak P, Perera F, Peterson B, Rundle A, Herbstman J, Goldsmith J, Rauh V. Prenatal exposure to air pollution is associated with childhood inhibitory control and adolescent academic achievement. ENVIRONMENTAL RESEARCH 2021;202. |
R827027 (2002) |
Exit Exit |
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Meyer IH, Whyatt RM, Perera FP, Ford JG. Risk for asthma in 1-year-old infants residing in New York City high-risk neighborhoods. Journal of Asthma 2003;40(5):545-550. |
R827027 (2002) R832141 (2005) R832141 (2007) R832141 (Final) |
Exit |
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Miller RL, Chew GL, Bell CA, Biedermann SA, Aggarwal M, Kinney PL, Tsai W-Y, Whyatt RM, Perera FP, Ford JG. Prenatal exposure, maternal sensitization, and sensitization in utero to indoor allergens in an inner-city cohort. American Journal of Respiratory and Critical Care Medicine 2001;164(6):995-1001. |
R827027 (2002) |
Exit Exit |
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Miller RL, Garfinkel R, Horton M, Camann D, Perera FP, Whyatt RM, Kinney PL. Polycyclic aromatic hydrocarbons, environmental tobacco smoke, and respiratory symptoms in an inner-city birth cohort. Chest 2004;126(4):1071-1078. |
R827027 (2002) R832141 (2006) R832141 (2007) R832141 (Final) R832141C002 (2004) |
Exit Exit |
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Patel MM, Hoepner L, Garfinkel R, Chillrud S, Reyes A, Quinn JW, Perera F, Miller RL. Ambient metals, elemental carbon, and wheeze and cough in New York City children through 24 months of age. American Journal of Respiratory and Critical Care Medicine 2009;180(11):1107-1113. |
R827027 (2002) R832141 (2007) R832141 (Final) R834509 (2011) R834509 (Final) |
Exit Exit Exit |
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Patel M, Quinn J, Jung K, Hoepner L, Diaz D, Perzanowski M, Rundle A, Kinney P, Perera F, Miller R. Traffic density and stationary sources of air pollution associated with wheeze, asthma, and immunoglobulin E from birth to age 5 years among New York City children. ENVIRONMENTAL RESEARCH 2011;111(8):1222-1229. |
R827027 (2002) R832141 (Final) |
Exit Exit |
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Perera FP, Whyatt RM, Jedrychowski W, Rauh V, Manchester D, Santella RM, Ottman R. Recent developments in molecular epidemiology: a study of the effects of environmental polycyclic aromatic hydrocarbons on birth outcomes in Poland. American Journal of Epidemiology 1998;147(3):309-314. |
R827027 (2002) |
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Perera FP, Jedrychowski W, Rauh V, Whyatt RM. Molecular epidemiologic research on the effects of environmental pollutants on the fetus. Environmental Health Perspectives 1999;107(S3):451-460. |
R827027 (2002) |
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Perera FP. Molecular epidemiology: on the path to prevention? Journal of the National Cancer Institute 2000;92(8):602-612. |
R827027 (2002) |
Exit Exit |
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Perera FP, Weinstein IB. Molecular epidemiology: recent advances and future directions. Carcinogenesis 2000;21(3):517-524. |
R827027 (2002) |
Exit Exit |
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Perera FP, Illman SM, Kinney PL, Whyatt RM, Kelvin EA, Shepard P, Evans D, Fullilove M, Ford JG, Miller RL, Meyer IH, Rauh VA. The challenge of preventing environmentally related disease in young children: community-based research in New York City. Environmental Health Perspectives 2002;110(2):197-204. |
R827027 (2002) |
Exit |
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Perera FP, Rauh V, Tsai W-Y, Kinney P, Camann D, Barr D, Bernert T, Garfinkel R, Tu Y-H, Diaz D, Dietrich J, Whyatt RM. Effects of transplacental exposure to environmental pollutants on birth outcomes in a multiethnic population. Environmental Health Perspectives 2003;111(2):201-205. |
R827027 (2002) R832141 (2005) R832141 (2006) R832141 (2007) R832141 (Final) |
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Perera FP, Tang D, Tu Y-H, Cruz LA, Borjas M, Bernert T, Whyatt RM. Biomarkers in maternal and newborn blood indicate heightened fetal susceptibility to procarcinogenic DNA damage. Environmental Health Perspectives 2004;112(10):1133-1136. |
R827027 (2002) R832141 (2007) R832141C001 (2005) |
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Perera FP, Rauh V, Whyatt RM, Tang D, Tsai WY, Bernert JT, Tu YH, Andrews H, Barr DB, Camann DE, Diaz D, Dietrich J, Reyes A, Kinney PL. A summary of recent findings on birth outcomes and developmental effects of prenatal ETS, PAH, and pesticide exposures. NeuroToxicology 2005;26(4):573-587. |
R827027 (2002) R832141 (2006) R832141 (2007) R832141 (Final) |
Exit Exit |
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Perera FP, Tang D, Rauh VA, Lester K, Tsai WY, Tu YH, Weiss L, Hoepner L, King J, Del Priore G, Lederman SA. Relationships among polycyclic aromatic hydrocarbon-DNA adducts, proximity to the World Trade Center, and effects on fetal growth. Environmental Health Perspectives 2005;113(8):1062-1067. |
R827027 (2002) R832141 (2005) R832141 (2007) |
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Perera FP, Rauh V, Whyatt RM, Tsai W-Y, Tang D, Diaz D, Hoepner L, Barr D, Tu Y-H, Camann D, Kinney P. Effect of prenatal exposure to airborne polycyclic aromatic hydrocarbons on neurodevelopment in the first 3 years of life among inner-city children. Environmental Health Perspectives 2006;114(8):1287-1292. |
R827027 (2002) R832141 (2006) R832141 (2007) |
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Perera F, Tang D, Whyatt R, Lederman SA, Jedrychowski W. DNA damage from polycyclic aromatic hydrocarbons measured by benzo[a]pyrene-DNA adducts in mothers and newborns from Northern Manhattan, the World Trade Center area, Poland, and China. Cancer Epidemiology, Biomarkers & Prevention 2005;14(3):709-714. |
R827027 (2002) R832141 (2006) R832141 (2007) R832141 (Final) R832141C001 (2005) |
Exit Exit |
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Perera F, Miao Y, Ross Z, Rauh V, Margolis A, Hoepner L, Riley K, Herbstman J, Wang S. Prenatal exposure to air pollution during the early and middle stages of pregnancy is associated with adverse neurodevelopmental outcomes at ages 1 to 3 years. ENVIRONMENTAL HEALTH 2024;23(1) |
R827027 (2002) |
Exit |
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Perzanowski MS, Miller RL, Thorne PS, Barr RG, Divjan A, Sheares BJ, Garfinkel RS, Perera FP, Goldstein IF, Chew GL. Endotoxin in inner-city homes: associations with wheeze and eczema in early childhood. Journal of Allergy and Clinical Immunology 2006;117(5):1082-1089. |
R827027 (2002) R832141 (2005) R832141 (2006) R832141 (2007) R832141 (Final) |
Exit Exit |
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Perzanowski MS, Miller RL, Tang D, Ali D, Garfinkel RS, Chew GL, Goldstein IF, Perera FP, Barr RG. Prenatal acetaminophen exposure and risk of wheeze at age 5 years in an urban low-income cohort. Thorax 2010;65(2):118-123. |
R827027 (2002) R832141 (2007) R832141 (Final) |
Exit Exit Exit |
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Rauh VA, Andrews HF, Garfinkel RS. The contribution of maternal age to racial disparities in birthweight: a multilevel perspective. American Journal of Public Health 2001;91(11):1815-1824. |
R827027 (2002) |
Exit Exit |
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Rauh VA, Chew GL, Garfinkel RS. Deteriorated housing contributes to high cockroach allergen level in inner-city households. Environmental Health Perspectives 2002;110(S2):323-327. |
R827027 (2002) |
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Rauh VA, Whyatt RM, Garfinkel R, Andrews H, Hoepner L, Reyes A, Diaz D, Camann D, Perera FP. Developmental effects of exposure to environmental tobacco smoke and material hardship among inner-city children. Neurotoxicology and Teratology 2004;26(3):373-385. |
R827027 (2002) R832141 (2005) R832141 (2006) R832141 (2007) R832141 (Final) |
Exit Exit |
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Rosa MJ, Divjan A, Hoepner L, Sheares BJ, Diaz D, Gauvey-Kern K, Perera FP, Miller RL, Perzanowski MS. Fractional exhaled nitric oxide exchange parameters among 9-year-old inner-city children. Pediatric Pulmonology 2011;46(1):83-91. |
R827027 (2002) R832141 (Final) |
Exit |
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Rundle AG, Gallagher D, Herbstman JB, Goldsmith J, Holmes D, Hassoun A, Oberfield S, Miller RL, Andrews H, Widen EM, Hoepner LA. Prenatal exposure to airborne polycyclic aromatic hydrocarbons and childhood growth trajectories from age 5-14 years. Environmental research 2019;177:108595. |
R827027 (2002) R832141 (Final) R834509 (Final) |
Exit Exit |
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Sax SN, Bennett DH, Chillrud SN, Kinney PL, Spengler JD. Differences in source emission rates of volatile organic compounds in inner-city residences of New York City and Los Angeles. Journal of Exposure Analysis and Environmental Epidemiology 2004;14(Suppl 1):S95-S109. |
R827027 (2002) R828678C001 (2004) R828678C001 (2006) R828678C001 (2007) R828678C001 (Final) R832141 (2006) R832141 (2007) R832141 (Final) |
Exit Exit |
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Sax SN, Bennett DH, Chillrud SN, Ross J, Kinney PL, Spengler JD. A cancer risk assessment of inner-city teenagers living in New York City and Los Angeles. Environmental Health Perspectives 2006;114(10):1558-1566. |
R827027 (2002) R828678C001 (2007) R828678C001 (Final) |
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Strunk RC, Ford JG, Taggart V. Reducing disparities in asthma care: priorities for research--National Heart, Lung, and Blood Institute workshop report. Journal of Allergy and Clinical Immunology 2002;109(2):229-237. |
R827027 (2002) |
Exit Exit |
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Tonne CC, Whyatt RM, Camann DE, Perera FP, Kinney PL. Predictors of personal polycyclic aromatic hydrocarbon exposures among pregnant minority women in New York City. Environmental Health Perspectives 2004;112(6):754-759. |
R827027 (2002) R832141 (2005) R832141 (2006) R832141 (2007) R832141 (Final) |
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Visness CM, Gebretsadik T, Jackson DJ, Myers JB, Havstad S, Lemanske RF, Hartert TV, Hershey GK, Zoratti EM, Martin LJ, Miller R. Asthma as an outcome:Exploring multiple definitions of asthma across birth cohorts in the Environmental influences on Child Health Outcomes Children's Respiratory and Environmental Workgroup. Journal of Allergy and Clinical Immunology 2019;144(3):866-9. |
R827027 (2002) |
Exit Exit |
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Wallace D, Wallace R, Rauh V. Community stress, demoralization and body mass index: evidence for social signal transduction. Social Science and Medicine 2003;56(12):2467-2478. |
R827027 (2002) R832141 (2005) R832141 (2006) R832141 (2007) |
Exit |
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Wallace D. Discriminatory Mass De-housing and Low-Weight Births:Scales of Geography, Time, and Level. JOURNAL OF URBAN HEALTH-BULLETIN OF THE NEW YORK ACADEMY OF MEDICINE 2011;88(3):454-468. |
R827027 (2002) |
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Wallace R, Wallace RG. Adaptive chronic infection, structured stress, and medical magic bullets: do reductionist cures select for holistic diseases? Biosystems 2004;77(1-3):93-108. |
R827027 (2002) R832141 (2006) R832141 (2007) R832141 (Final) |
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Wang Y, Perera F, Guo J, Riley K, Durham T, Ross Z, Ananth C, Baccarelli A, Wang S, Herbstman J. A methodological pipeline to generate an epigenetic marker of prenatal exposure to air pollution indicators. Epigenetics 2021;1-9. |
R827027 (2002) R832141 (Final) R834509 (Final) |
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Whyatt RM, Perera FP, Jedrychowski W, Santella RM, Garte SJ, Bell DA. Association between polycyclic aromatic hydrocarbon-DNA adduct levels in maternal and newborn white blood cells and Glutathione S-Transferase P1 and CYP1A1 polymorphisms. Cancer Epidemiology, Biomarkers & Prevention 2000;9(2):207-212. |
R827027 (2002) |
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Whyatt RM, Barr DB. Measurement of organophosphate metabolites in postpartum meconium as a potential biomarker of prenatal exposure:a validation study. Environmental Health Perspectives 2001;109(4):417-420. |
R827027 (2002) |
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Whyatt RM, Jedrychowski W, Hemminki K, Santella RM, Tsai WY, Yong K, Perera FP. Biomarkers of polycyclic aromatic hydrocarbon-DNA damage and cigarette smoke exposures in paired maternal and newborn blood samples as a measure of differential susceptibility. Cancer Epidemiology Biomarkers and Prevention 2001;10(6):581-588. |
R827027 (2002) |
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Whyatt RM, Barr DB, Camann DE, Kinney PL, Barr JR, Andrews HF, Hoepner LA, Garfinkel R, Hazi Y, Reyes A, Ramirez J, Cosme Y, Perera FP. Contemporary-use pesticides in personal air samples during pregnancy and blood samples at delivery among urban minority mothers and newborns. Environmental Health Perspectives 2003;111(5):749-756. |
R827027 (2002) R828609 (2002) R828609 (2004) R832141 (2005) R832141 (2006) R832141 (2007) |
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Whyatt RM, Camann D, Perera FP, Rauh VA, Tang D, Kinney PL, Garfinkel R, Andrews H, Hoepner L, Barr DB. Biomarkers in assessing residential insecticide exposures during pregnancy and effects on fetal growth. Toxicology and Applied Pharmacology 2005;206(2):246-254. |
R827027 (2002) R828609 (2004) R832141 (2005) R832141 (2006) R832141 (2007) R832141 (Final) |
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Widen E, Burns N, Daniels M, Backlund G, Rickman R, Foster S, Nichols A, Hoepner L, Kinsey E, Ramireaz-Carvey J. Gestational weight change and childhood body composition trajectories from pregnancy to early adolescence. Obesity 10;. |
R827027 (2002) R832141 (Final) R834509 (Final) |
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Widen E, Nichols A, Kahn L, Factor-Livak P, Insel B, Hoepner L, Dube S, Rauh V, Perera F, Rundel A. Prepregnancy obesity is associated with cognitive outcomes in boys in a low-income, multiethnic birth cohort. BMC Pediatrics 2019;19(1):507. |
R827027 (2002) R834509 (Final) |
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Zeinomar N, Grant-Alfieri A, Burke K, de Hoz M, Tehranifar P, Walker D, Morton T, Shepard P, Herbstman J, Miller R, Pera F, Terry M. Cancer Risk Reduction Through Education of Adolescents:Development of a Tailored Cancer Risk-Reduction Educational Tool. Journal of Cancer Education 2021;. |
R827027 (2002) R832141 (Final) R834509 (Final) |
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Supplemental Keywords:
RFA, Health, Scientific Discipline, Economic, Social, & Behavioral Science Research Program, Air, Geographic Area, particulate matter, Health Risk Assessment, State, environmental justice, Epidemiology, Risk Assessments, Allergens/Asthma, Disease & Cumulative Effects, Biochemistry, Children's Health, Ecological Risk Assessment, asthma, sensitive populations, environmental health, particulates, ambient air quality, air toxics, community-based intervention, air pollutants, lung disease, human health effects, hazardous environmental exposures, second hand smoke, airway disease, environmental risks, age-related differences, developmental toxicity, pulmonary disease, exposure, airway inflammation, children, air pollution, environmental health effects, airborne pollutants, childhood respiratory disease, inner city toxicants, human exposure, particulate exposure, children's environmental health, epidemeology, ambient particulates, environmental toxicant, harmful environmental agents, Acute health effects, epidemiological studies, environmental toxicants, PM, tobacco smoke, aersol particles, indoor air quality, community based intervention, urban environmental exposure, indoor environment, disease, New York (NY), risk and vulnerabilityProgress and Final Reports:
Subprojects under this Center: (EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
R827027C001 Community-Based Intervention: Reducing Risks of Asthma
R827027C002 Growth and Development/Evaluation of Carcinogenic Risks
R827027C003 Research Project on Asthma
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.