Grantee Research Project Results
Research Centers
Columbia University School of Public Health
Columbia University in the City of New York
The mission of the Columbia Center for Children's Environmental Health (CCCEH) is to undertake a comprehensive community-based assessment of environmental risks to infants and children, and to develop strategies for reducing, and ultimately preventing, those risks. The Center is responsive to the urgent health needs of the minority communities in Northern Manhattan and the South Bronx, which suffer uniquely high rates of asthma, adverse birth outcomes, impaired development, and other diseases. These communities also have disproportionately heavy exposure to environmental pollutants, which may contribute to these adverse health outcomes.
Community participation is an integral component of both the Center's organizational structure and its research projects. We anticipate that research results will aid the development of community-based strategies to reduce and ultimately prevent asthma and developmental impairment in the target population, and will have implications for the control of these health risks in other inner-city, minority communities. Thus, the Center is responsive to the need for environmental justice.
The Center utilizes an innovative approach -molecular epidemiology - to answer questions regarding environmental impacts on children's health. Biomarkers will be used in conjunction with questionnaires, individual exposure assessment, clinical evaluations, and quantitative measures of community-level risk factors to evaluate exposure, susceptibility, and risk from the environmental toxicants of concern, and to monitor the efficacy of intervention. The main hypotheses of the Center are that: 1) prenatal and postnatal environmental exposures to airborne particulate matter (PM), polycyclic aromatic hydrocarbons (PAH), environmental tobacco smoke (ETS), and home allergens (cockroach, house dust mite and rodent) increase the risk of asthma and/or developmental impairment in these disadvantaged communities; 2) inadequate nutritional status exacerbates the impact of these environmental toxicants; and 3) a community-based intervention to reduce these toxic exposures and improve nutritional status can reduce the risk of disease.
To test these hypotheses and meet its objective, the Center is undertaking three interrelated research studies, all of which build on a prospective cohort of 400 African American and Dominican mothers and their newborn infants living in Washington Heights, Harlem and the South Bronx. The research studies (described in detail below) include projects that investigate the impact of environmental pollutants and allergens on: 1) growth and development; and 2) asthma. The third research study investigates the impact of community and home-based interventions to reduce toxicant and allergen exposure, as well as risk of asthma.
Identifier | Abstract | Principal Investigator |
Annual/ Final Reports |
Pubs Count | Institution | Grant Representative |
Grant Amount |
Project Period |
|
---|---|---|---|---|---|---|---|---|---|
1 |
R827027
Centers - Main center abstract - Water Environment and Reuse Foundation's National Center for Resource Recovery and Nutrient Management |
Centers of Excellence in Children's Environmental Health and Disease Prevention Research |
Perera, Frederica P.
- Principal Investigators listed are sub-PIs determined by the center. |
Row 1: 2002
|
Row 1 Total Pubs:
91 Row 1 Journals: 73 -- Row 1: No Books -- |
Columbia University in the City of New York | Callan, Richard | $3,136,357 |
August 01, 1998 - July 31, 2003 (Extended to October 31, 2004) |
2 |
R827352
Centers - Main center abstract - Southern California Particle Center |
Southern California Particle Center and Supersite (SCPCS) |
Froines, John R. Arey, Janet Atkinson, Roger Avol, Edward L. Berhane, Kiros Cass, Glen Charles, Judith M. Cho, Arthur K. Cohen, Yoram Colome, Steven D. Eastmond, David A. Eldering, Annmarie Friedlander, Sheldon Fukuto, Jon Gauderman, William Gong, Henry Grosser, Stella C. Hankinson, Oliver Harkema, Jack Hinds, William C. Kleinman, Michael T. Kumagai, Yoshito Kunzli, Nino Langholz, Brian Linn, William S. Lurmann, Fred McConnell, Rob Scot Miguel, Antonio Nel, Andre E. Peters, John M. Phalen, Robert Que Hee, Shane S. Ritz, Beate R. Schiestl, Robert H. Sioutas, Constantinos Stram, Dan Thomas, Duncan C. Turco, Richard Venkatesan, M. Indira Winer, Arthur M. Yu, Rong Chun Ziemann, Paul J. - Principal Investigators listed are sub-PIs determined by the center. |
Row 2: 2003
|
Row 2 Total Pubs:
150 Row 2 Journals: 149 -- Row 2: No Books -- |
University of California - Los Angeles, Michigan State University, Rancho Los Amigos Medical Center, University of California - Davis, University of California - Irvine, University of California - Riverside, University of Southern California, University of Tsukuba | Chung, Serena | $8,715,583 |
June 01, 1999 - May 31, 2005 (Extended to May 31, 2006) |
3 |
R831861
Centers - Main center abstract - Southern California Children's Environmental Health Center |
Children’s Environmental Health Center |
Gilliland, Frank D. Avol, Edward L. Berhane, Kiros Diaz-Sanchez, David Dubeau, Louis Froines, John R. Gauderman, William Gong, Henry Hricko, Andrea M. Kuenzli, Nino Linn, William S. Lurmann, Fred McConnell, Rob Scot Peters, John M. Riedl, Marc A - Principal Investigators listed are sub-PIs determined by the center. |
Row 3: 2004
|
Row 3 Total Pubs:
200 Row 3 Journals: 129 Row 3 Books: 1 |
University of Southern California, University of California - Los Angeles | Callan, Richard | $3,802,622 |
November 01, 2003 - October 31, 2008 (Extended to October 31, 2010) |
4 |
R832141
Centers - Main center abstract - Water Environment and Reuse Foundation's National Center for Resource Recovery and Nutrient Management |
Columbia Center for Children's Environmental Health |
Perera, Frederica P. Andrews, Howard F. Barr, R. Graham Chew, Ginger Davidson, Leslie Evans, David Fullilove, Mindy Garfinkel, Robin S. Goldstein, Inge Hatzis, Dimitrios Kinney, Patrick L. Lederman, Sally Ann Matseoane, Stephen Miller, Rachel L. Orjuela, Manuela Perzanowski, Matt Rauh, Virginia Rothman, Paul B. Sheares, Beverley Shepard, Peggy Tang, Deliang Tsai, Wei-Tann Watkins, Beverly Whyatt, Robin M. Zivin, Joshua - Principal Investigators listed are sub-PIs determined by the center. |
Row 4: 2004
|
Row 4 Total Pubs:
172 Row 4 Journals: 157 Row 4 Books: 3 |
Columbia University in the City of New York | Callan, Richard | $4,435,198 |
November 01, 2003 - October 31, 2008 (Extended to October 31, 2010) |
5 |
R832413
Centers - Main center abstract - Southern California Particle Center |
Southern California Particle Center (SCPC) |
Froines, John R. Cho, Arthur K. Delfino, Ralph Fine, Philip M. Fukuto, Jon Harkema, Jack Hinds, William C. Kleinman, Michael T. Kumagai, Yoshito Lusis, Aldons Miguel, Antonio Nel, Andre E. Neuhausen, Susan Schauer, James J. Shafer, Martin M. Sioutas, Constantinos Staimer, Norbert Stram, Dan Vaziri, Nosratola D Vaziri, Nostratola Zhu, Yifang - Principal Investigators listed are sub-PIs determined by the center. |
Row 5: 2006
|
Row 5 Total Pubs:
154 Row 5 Journals: 139 -- Row 5: No Books -- |
Michigan State University, University of California - Los Angeles, University of California - Irvine, University of Southern California, University of Tsukuba, University of Wisconsin - Madison | Chung, Serena | $7,999,994 |
October 01, 2005 - September 30, 2010 (Extended to September 30, 2012) |
6 |
R834509
Centers - Main center abstract - The Columbia Center for Children’s Environmental Health |
The Columbia Center for Children’s Environmental Health |
Perera, Frederica P. Andrews, Howard F. Champagne, Frances Evans, David Freyer, Greg Garfinkel, Robin S. Miller, Rachel L. Moore, Holly Oberfield, Sharon Peterson, Brad Rauh, Virginia Rundle, Andrew Shepard, Peggy Tang, Deliang Whyatt, Robin M. - Principal Investigators listed are sub-PIs determined by the center. |
Row 6: 2011
|
Row 6 Total Pubs:
103 Row 6 Journals: 59 Row 6 Books: 2 |
Columbia University in the City of New York, Columbia University Mailman School of Public Health, Resources for the Future, West Harlem Environmental Action (WE ACT for Environmental Justice) | Callan, Richard | $3,953,320 |
September 24, 2009 - September 23, 2014 (Extended to September 23, 2015) |
7 |
R835441
Centers - Main center abstract - Southern California Children's Environmental Health Center |
Southern California Children's Environmental Health Center |
McConnell, Rob Scot Allayee, Hooman Berhane, Kiros Bouret, Sebastien G. Finch, Caleb E Gilliland, Frank D. Goran, Michael Hricko, Andrea M. Johnston, Jill Mittelman, Steven Morgan, Todd Nayak, Krishna S. Sattler, Fred R Sioutas, Constantinos - Principal Investigators listed are sub-PIs determined by the center. |
Row 7: 2014
|
Row 7 Total Pubs:
66 Row 7 Journals: 63 -- Row 7: No Books -- |
University of Southern California | Hahn, Intaek | $4,146,875 |
July 01, 2013 - June 30, 2018 (Extended to June 30, 2019) |
8 |
R835567
Centers - Main center abstract - Water Environment and Reuse Foundation's National Center for Resource Recovery and Nutrient Management |
Water Environment and Reuse Foundation (WE&RF)'s National Center for Resource Recovery and Nutrient Management |
Chandran, Kartik Olabode, Lola Pramanik, Amit Case, Traci L. Frear, Craig Khunjar, Wendell Luthy, Richard G. Radke, Christine Sedlak, David L. Skerlos, Steven J. Stack, William Stensel, David Wigginton, Krista Yorgey, Georgine - Principal Investigators listed are sub-PIs determined by the center. |
Row 8: 2014
|
Row 8 Total Pubs:
82 Row 8 Journals: 24 -- Row 8: No Books -- |
Columbia University in the City of New York, Water Environment and Reuse Foundation, Center for Watershed Protection, Hazen and Sawyer, Stanford University, University of California - Berkeley, University of Michigan, University of Washington, Washington State University, Water Research Foundation | Packard, Benjamin H | $3,370,298 |
November 01, 2013 - October 31, 2018 |
9 |
R835569
Centers - Main center abstract - Center for Reinventing Aging Infrastructure for Nutrient Management |
Center for Reinventing Aging Infrastructure for Nutrient Management (RAINmgt) |
Mihelcic, James R. Anderson, Damann Boyer, Treavor H. Butcher, Melissa Coney, Earnest Cornejo-Warner, Pablo Cunningham, Jeffrey A. Dao, Hang Davis, Allen Diaz-Elsayed, Nancy Dick, George Ergas, Sarina Henderson, Michelle Igielski, Sara Ishii, Stephanie Issacs, Wainella Kuwayama, Yusuke Locicero, Ryan Lopez, Emma Lynn, Thomas Mireles, Shelby Olmstead, Sheila Orner, Kevin Ozcan, Onur Payne, Karl Rankin, Laura Richardson, Nathan Rodriguez-Gonzalez, Laura Saetta, Daniella Schwartz, Sara Shih, Jhih-Shyang Trotz, Maya Wang, Ranran Xu, Jian Xu, Xiaofan Yeh, Daniel H Zhang, Qiong Zimmerman, Julie B. - Principal Investigators listed are sub-PIs determined by the center. |
Row 9: 2014
|
Row 9 Total Pubs:
87 Row 9 Journals: 20 Row 9 Books: 1 |
University of South Florida, Arizona State University, Corporation to Develop Communities of Tampa, Hazen and Sawyer, Resources for the Future, The University of Texas at Austin, University of Florida, University of Maryland - College Park, Yale University | Packard, Benjamin H | $3,123,375 |
September 01, 2013 - August 31, 2018 |
10 |
R836154
Centers - Main center abstract - Southern California Children's Environmental Health Center |
The Columbia Center for Childrens Environmental Health |
Perera, Frederica P. Hernandez, Diana Peterson, Bradley S Rauh, Virginia Rundle, Andrew Shepard, Peggy - Principal Investigators listed are sub-PIs determined by the center. |
Row 10: 2016
|
Row 10 Total Pubs:
10 Row 10 Journals: 9 -- Row 10: No Books -- |
Columbia University in the City of New York, University of Southern California | Callan, Richard | $2,552,707 |
September 01, 2015 - August 31, 2019 (Extended to August 31, 2020) |
11 |
R836158
Centers - Main center abstract - Maternal and Developmental Risks from Environmental and Social Stressors (MADRES) Center for Environmental Health Disparities Research |
Maternal and Developmental Risks from Environmental and Social Stressors (MADRES) Center for Environmental Health Disparities Research |
Gilliland, Frank D. Van Doren Breton, Carrie Bastain, Theresa Frilund Cockburn, Myles G Dunton, Genevieve Frilund Hricko, Andrea M. - Principal Investigators listed are sub-PIs determined by the center. |
Row 11: 2016
|
Row 11 Total Pubs:
13 Row 11 Journals: 9 -- Row 11: No Books -- |
University of Southern California | Callan, Richard | $1,500,000 |
July 01, 2015 - June 30, 2020 (Extended to June 30, 2021) |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.