Grantee Research Project Results
Publications Details for Grant Number R831709
Center for Child Environmental Health Risks Research
RFA:
Centers for Children's Environmental Health and Disease Prevention Research (2003)
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| Reference Type | Citation | Progress Report Year | Document Sources |
|---|---|---|---|
| Abstract | Cole, TB, Walter, BJ. Contribution of paraoxonase (PON1) levels and Q192R genotype to organophosphate detoxication:evidence from humans and "humanized" transgenic mice. The Toxicologist 2003;72(Suppl 1):100. |
R831709 (2005) R831709 (2007) |
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| Abstract | Faustman EM, Yu X, Sidhu J, Robinson J. Toxicant affects on ubiquitin-proteosome systems: lessons from cross-compound and cross-system assessments. The Toxicologist 2005;84(S1):1655. |
R831709 (Final) R831709C001 (2005) |
not available |
| Abstract | Faustman EM, Griffith WC, Vigoren E. Lessons learned from longitudinal studies to identify high exposure groups using OP pesticide urinary biomarkers. Toxicology Letters 2006;164(Suppl 1):S161. |
R831709 (2005) R831709 (2007) R831709 (Final) R831709C001 (2007) |
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| Abstract | Furlong CE, Rieder MJ, Carlson CS, Nickerson DA, Jampsa RL, Costa LG, Jarvik GP. New polymorphisms in the human paraoxonase (PON1) gene. The Toxicologist 2003;72(Suppl 1):100. |
R831709 (2005) R831709 (2007) |
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| Abstract | Garry MR, Sidhu JS. Differential modulation of stress and ubiquitination signaling pathways by Cadmium, H202, and serum withdrawal in cultrued mouse fibroblasts. The Toxicologist 2003;72:311. |
R831709 (2005) |
not available |
| Abstract | Giordano G, Afsharinejad Z, Kavanagh T, Costa L. Reactive oxygen species mediate the neurotoxicity induced by organophosphorus insecticides in mouse cerebellar granule cells. The Toxicologist 2006;90(1):301. |
R831709 (2005) R831709 (2006) R831709C001 (2006) R831709C001 (2007) |
not available |
| Abstract | Giordano G, Afsharinejad Z, Kavanagh T, Costa L. Reactive oxygen species mediate the neurotoxicity induced by organophosphorous insecticides in mouse cerebellar granule cells. The Toxicologist CD-An Official Journal of the Society of Toxicology 2006;90(S-1):1472a. |
R831709 (2007) |
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| Abstract | Gohlke J, Griffith W, Faustman EM. Evaluation of interspecies variability during neocortical neurogenesis using biologically based computational models. The Toxicologist 2003;72 (Suppl 1):179. |
R831709 (2005) R831709 (2007) |
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| Abstract | Gribble E, Mendoza A. Evaluation of cell cycle kinetics in p53 mouse embryonal fibroblasts: effects of methylmercury. The Toxicologist 2003;72:322. |
R831709 (2005) |
not available |
| Abstract | Gribble E, Hong S. Kinetic and dynamic characterization of a mouse embryonal mesencephalon neuronal precursor cell culture. Birth Defects Research Part A-Clinical Molecular Teratology 2005;73(5):301. |
R831709 (2005) |
not available |
| Abstract | Gribble EJ, Yu X, Hong S, Faustman EM. A role for p53 in mouse midbrain neural precursor cell (NPC) cell cycle arrest and premature neuronal differentiation following methylmercury exposure. The Toxicologist 2006;90:366. |
R831709 (2005) R831709 (2006) R831709C001 (2006) |
not available |
| Abstract | Griffith W, Gohlke J. Building BBDR models for cell signaling pathways using transgenic animal models. The Toxicologist 2003;72:182. |
R831709 (2005) |
not available |
| Abstract | Griffith W, DeFrank N. Systems biology models for integration of diverse studies of the developing neocortex after exposure to low dose radiation from external and internal sources. The Toxicologist 2006;90:336. |
R831709 (2005) |
not available |
| Abstract | Hong S, Sidhu JS, Kim E, Faustman EM. Refinement of a high-throughput 2D-PAGE technique for the evaluation of ubiquitin-conjugated protein status induced by developmental toxicants. The Toxicologist: Supplement to Toxicological Sciences 2003;72(Supplement 1):732. |
R831709 (2007) |
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| Abstract | Hong S, Sidhu J. Refinement of high-throughput 2D-Page technique for the evaluation of ubiquitin-conjugated protein status induced by developmental toxicants. The Toxicologist 2003;72:732. |
R831709 (2005) |
not available |
| Abstract | Kissel J, Kedan G, Wawrukiewicz A, Fenske RA. Attempted reconciliation of predicted children's exposures to organophosphate pesticides with measured metabolite levels in urine. Epidemiology 1999;10(4):S110. |
R826886C004 (2001) R831709 (2005) R831709 (Final) |
not available |
| Abstract | Robinson J, Yu X, Hong S, Kim E, Sullivan R, Griffith W, Faustman E. Differential impact of cadmium on gene expression during neuralation in the C57BL/6 and SWV. Birth Defects Research Part A 2006;76(5):392. |
R831709 (2005) R831709 (2006) R831709C001 (2006) |
not available |
| Abstract | Robinson JF, Yu X, Gribble EJ, Hong S, Kim E, Sidhu JS, Faustman EM. Examination of arsenic-induced alterations in cell cycle progression and global gene expression in p53 transgenic mouse embryonic fibroblasts. The Toxicologist 2006;90:91-92. |
R831709 (2005) R831709 (2006) R831709C001 (2006) |
not available |
| Abstract | Sidhu J, Hong S. Methylmercury induces differential ubiquitin conjugated protein levels in p53 variant mouse embryonal biroblasts. The Toxicologist 2003;72:323. |
R831709 (2005) |
not available |
| Abstract | Takaro T, Griffith W. Asbestos and radiation as combined exposures in pulmonary fibrosis. The Toxicologist 2003;72:220. |
R831709 (2005) |
not available |
| Abstract | Yu X, Griffith W, Hanspers K, Robinson J, Faustman EM. Functional interpretation of dose-and time-dependent microarray data: quantitative integration of GO ontology analysis for toxicology and risk assessment. The Toxicologist 2006;90(1):182-183. |
R831709 (2005) R831709 (2006) R831709C001 (2006) R831709C001 (2007) |
not available |
| Abstract | Yu X, Griffith WC, Hanspers K, Ong H, Faustman EM. A system based approach to identify potential signalling pathways during gonad development from microarray data. Birth Defects Research Part A 2006;76(5):339. |
R831709 (2005) R831709 (2006) R831709C001 (2006) |
not available |
| Book | Costa LG, Eaton DL, eds. Gene-Environment Interactions: Fundamentals of Ecogenetics. Hoboken, NJ: John Wiley & Sons, Inc., March 2006, 557 pp. |
R831709 (2006) R831709 (2007) R831709 (Final) R831709C002 (2006) |
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| Book Chapter | Battuello K, Furlong C, Fenske R, Austin MA, Burke W. Paraoxonase polymorphisms and susceptibility to organophosphate pesticides. In:Khoury MJ, Little J, Burke W, eds. Human Genome Epidemiology:A Scientific Foundation for Using Genetic Information To Improve Health and Prevent Disease. Oxford, UK:Oxford University Press, 2004, Chapter 18, pp. 305-321. |
R831709 (2005) R831709 (2007) R831709 (Final) R831709C002 (2004) |
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| Book Chapter | Brophy VH, Jarvik GP, Furlong CE. PON1 polymorphisms. In: Costa LG, Furlong CE, eds. Paraoxonase (PON1) in Health and Disease: Basic and Clinical Aspects. Boston, MA: Springer, 2002, Chapter 3, pp. 53-77. |
R826886 (2000) R826886C002 (2001) R826886C002 (2002) R831709 (2007) |
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| Book Chapter | Brophy VH, Jarvik PG. PON1 polymorphisms. In: Costa L, Furlong C, eds. Paraoxonase (PON1) in Health and Disease: Basic and Clinical Aspects. Norwell, MA: Kluwer Academic Publishers, 2002, Chapter 3, pp. 53-77. |
R831709 (2005) |
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| Book Chapter | Costa LG, Li W-F, Richter RJ, Shih DM, Lucis AJ, Furlong CE. PON1 and organophosphate toxicity. In: Costa LG, Furlong CE, eds. Paraoxonase(PON1) in Health and Disease: Basic and Clinical Aspects. Boston, MA: Springer, 2002, Chapter 8, pp. 165-183. |
R826886 (2000) R831709 (2005) R831709 (Final) |
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| Book Chapter | Costa LG, Furlong CE. Paraoxonase (PON1) gene polymorphisms. In: Fuchs J, Podda M, eds. Encyclopedia of Medical Genomics and Proteomics. New York, NY: Taylor & Francis, 2004, pp. 965-969. |
R831709 (2007) R831709 (Final) R831709C002 (2004) |
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| Book Chapter | Costa LG, Cole TB, Vitalone A, Furlong CE. Paraoxonase polymorphisms and toxicity of organophosphates. In: Gupta RC, ed. Toxicology of Organophosphate and Carbamate Compounds. Amsterdam: Elsevier, Inc., December 2005, pp. 247-255. |
R831709 (2007) R831709 (Final) |
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| Book Chapter | Costa LG, Cole TB, Vitalone A, Furlong CE. Paraoxonase (PON1) polymorphisms and toxicity of organophosphates. In: Gupta RC, ed. Toxicology of Organophosphates & Carbamate Compounds. San Diego, CA: Academic Press, 2005, Chapter 18, pp. 247-255. |
R831709 (2005) R831709 (2006) R831709 (Final) R831709C002 (2005) R831709C002 (2006) |
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| Book Chapter | Costa LG, Cole TB, Geiss GK, Furlong CE. Paraoxonase, butyrylcholinesterase, and epoxide hydrolase. In: Costa LG, Eaton DL, eds. Gene-Environment Interactions: Fundamentals of Ecogenetics. Hoboken, NJ: John Wiley & Sons, Inc., 2006, Chapter 9, pp. 159-177. |
R831709 (2005) R831709 (2007) R831709 (Final) R831709C002 (2004) R831709C002 (2006) |
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| Book Chapter | Costa LG. Receptors and ion channels. In: Costa LG, Eaton DL, eds. Gene-Environment Interactions:Fundamentals of Ecogenetics. Hoboken, NJ: John Wiley & Sons, Inc., 2006, Chapter 11, pp. 197-210. |
R831709 (2005) R831709 (2007) R831709 (Final) R831709C002 (2006) |
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| Book Chapter | Costa LG. Toxic effects of pesticides. In: Klaassen CD, ed. Casarett & Doull’s Toxicology: The Basic Science of Poisons, 7th Edition. New York, NY: McGraw-Hill, 2007, Chapter 22, pp. 883-932. |
R831709 (2005) R831709 (2007) R831709 (Final) R831709C002 (2007) |
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| Book Chapter | Costa LG, Furlong CE. Paraoxonase 1: structure, function and polymorphisms. In: Satoh T, Gupta RC, eds. Anticholinesterase Pesticides: Metabolism, Neurotoxicity and Epidemiology. Hoboken, NJ: John Wiley & Sons, 2011, Chapter 7, pp. 85-95. |
R831709 (Final) R834514 (2011) R834514 (2012) R834514 (2013) R834514 (Final) |
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| Book Chapter | Costa LG. Receptors and ion channels. In: Costa LG, Eaton DL, eds. Gene-Environment Interactions: Fundamentals of Ecogenetics. Hoboken, NJ: John Wiley & Sons, 2006. |
R831709 (2006) R831709 (Final) |
not available |
| Book Chapter | Costa LG, Cole TB, Geiss GK, Furlong CE. Paraoxonase, butyrylcholinesterase, and epoxide hydrolase. In: Costa LG, Eaton DL, eds. Gene-Environment Interactions: Fundamentals of Ecogenetics. Hoboken, NJ: John Wiley & Sons, 2006. |
R831709 (2006) R831709 (Final) |
not available |
| Book Chapter | Farrow, RS, Wong E, Ponce RA, Faustman EM, Zerbe RO. Facilitating regulatory design and stakeholder participation: the FERET template with an application to the Clean Air Act. In: Fischbeck PS, Farrow RS, eds. Improving Regulation: Cases in Environment, Health and Safety. Washington, DC: Resources for the Future Press, 2001, Chapter 19, pp. 429-442. |
R831709 (2005) R831709 (2007) |
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| Book Chapter | Faustman EM, Gohlke JM, Ponce RA, Lewandowski TA, Seeley MR, Whittaker SG, Griffith WC. Experimental approaches to evaluate mechanisms of developmental toxicity. In: Hood RD, ed. Developmental and Reproductive Toxicology: A Practical Approach, 2nd edition. Boca Raton, FL: CRC Press, Inc., 2005, Chapter 2, pp. 15-60. |
R831709 (2005) R831709 (2007) R831709 (Final) R831709C001 (2004) |
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| Book Chapter | Faustman EM, Omenn GS. Risk assesssment and the impact of ecogenetics. In:Costa LG, Eaton DL, eds. Gene-Environment Interactions: Fundamentals of Ecogenetics, Hoboken, NJ: John Wiley & Sons, Inc., 2006, Chapter 25, pp. 427-450. |
R831709 (2005) R831709 (2007) R831709 (Final) |
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| Book Chapter | Furlong CE, Li W-F, Cole TB, Jampsa R, Richter RJ, Jarvik GP, Shih DM, Tward A, Lusis AJ, Costa LG. Understanding the significance of genetic variability in the human PON1 gene. In: Valdes JJ, Sekowski JW, eds. Toxicogenomics and Proteomics, NATO Science Series: Life and Behavioural Sciences, Volume 356. Amsterdam, Netherlands: IOS Press, 2004. |
R831709 (2007) R831709 (Final) R831709C002 (2004) |
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| Book Chapter | Kelada SN, Checkoway H, Costa LG. Neurodegenerative diseases. In: Costa LG, Eaton DL, eds. Gene-Environment Interactions: Fundamentals of Ecogenetics. Hoboken, NJ: John Wiley & Sons, Inc., 2006, Chapter 15, pp. 253-269. |
R831709 (2005) R831709 (2006) R831709 (2007) R831709C002 (2006) |
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| Book Chapter | Kirchner SC, Faustman EM. Identifying mechanisms of developmental toxicity: application of tools from molecular biology. In: Puga A, Wallace KB, eds. Molecular Biology of the Toxic Response. London, UK: Taylor and Francis Publishers, 1999, Chapter 24, pp. 411-437. |
R831709 (2005) R831709 (2007) |
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| Book Chapter | Yu X, Ponce RA, Faustman EM. Metals induced disruption of ubiquitin proteasome system, activation of stress signaling and apoptosis. In: Banfalvi G, ed. Cellular Effects of Heavy Metals. Dordrecht, Netherlands: Springer, 2011, Chapter 14, pp. 291-311. |
R831709 (Final) R834514 (2011) R834514 (Final) |
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| Book Chapter | Hofmann JN, Keifer MC, Checkoway H, De Roos AJ, Farin FM, Fenske RA, Richter RJ, van Belle G, Furlong CE. Biomarkers of sensitivity and exposure in Washington state pesticide handlers. In: Paraoxonases in Inflammation, Infection, and Toxicology. Totowa, NJ: Humana Press, 2010, pp.19-27. |
R831709 (Final) |
not available |
| Book Chapter | Costa, L.G., G. Giordano, and M. Guizzetti. In vitro approaches to developmental neurotoxicity. In: Reproductive and Developmental Toxicology. New York, NY:Elsevier, 2011, pp. 159-166. |
R831709 (Final) |
not available |
| Journal Article | Bal-Price AK, Sunol C, Weiss DG, van Vliet E, Westerink RHS, Costa LG . Application of in vitro neurotoxicity testing for regulatory purposes:Symposium III summary and research needs. Neurotoxicology 2008;29(3):520-531. |
R831709 (2007) R831709 (Final) |
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| Journal Article | Bartell SM, Ponce RA, Sanga RN, Faustman EM. Human variability in mercury toxicokinetics and steady state biomarker ratios. Environmental Research 2000;84(2):127-132. |
R831709 (2007) |
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| Journal Article | Bekris LM, Shephard C, Janer M, Graham J, McNeney B, Shin J, Zarghami M, Griffith W, Farin F, Kavanagh TJ, Lernmark A. Glutamate cysteine ligase catalytic subunit promoter polymorphisms and associations with type 1 diabetes age-at-onset and GAD65 autoantibody levels. Experimental and Clinical Endocrinology and Diabetes 2007;115(4):221-228. |
R831709 (2005) R831709 (2007) R831709 (Final) R832733 (2007) |
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| Journal Article | Brophy VH, Jampsa RL, Clendenning JB, McKinstry LA, Jarvik GP, Furlong CE. Effects of 5' regulatory-region polymorphisms on paraoxonase-gene (PON1) expression. American Journal of Human Genetics 2001;68(6):1428-1436. |
R826886 (2000) R826886C002 (2001) R831709 (2007) |
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| Journal Article | Burry M, Guizzetti M, Oberdoerster J, Costa LG. Developmental neurotoxicity of toluene:in vivo and in vitro effects on astroglial cells. Developmental Neuroscience 2003;25(1):14-19. |
R831709 (2005) R831709 (2007) R831709 (Final) |
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| Journal Article | Caughlan A, Newhouse K, Namgung U, Xia Z. Chlorpyrifos induces apoptosis in rat cortical neurons that is regulated by a balance between p38 and ERK/JNK MAP kinases. Toxicological Sciences 2004;78(1):125-134. |
R831709 (2007) R831709C001 (2004) |
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| Journal Article | Cole TB, Jampsa RL, Walter BJ, Arndt TL, Richter RJ, Shih DM, Tward A, Lusis AJ, Jack RM, Costa LG, Furlong CE. Expression of human paraoxonase (PON1) during development. Pharmacogenetics 2003;13(6):357-364. |
R831709 (2005) R831709 (2007) R831709 (Final) |
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| Journal Article | Cole TB, Walter BJ, Shih DM, Tward AD, Lusis AJ, Timchalk C, Richter RJ, Costa LG, Furlong CE. Toxicity of chlorpyrifos and chlorpyrifos oxon in a transgenic mouse model of the human paraoxonase (PON1) Q192R polymorphism. Pharmacogenetics and Genomics 2005;15(8):589-598. |
R831709 (2005) R831709 (Final) R831709C002 (2005) |
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| Journal Article | Cole TB, Jansen K, Park S, Li W-F, Furlong CE, Costa LG. The toxicity of mixtures of specific organophosphate compounds is modulated by paraoxonase 1 status. Advances in Experimental Medicine and Biology 2010;660:47-60. |
R831709 (2007) R831709 (Final) R834514 (2011) R834514 (2012) R834514 (2013) R834514C004 (Final) |
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| Journal Article | Coronado GD, Thompson B, Strong L, Griffith WC, Islas I. Agricultural task and exposure to organophosphate pesticides among farmworkers. Environmental Health Perspectives 2004;112(2):142-147. |
R831709 (2005) R831709 (2007) R831709 (Final) R831709C003 (2004) |
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| Journal Article | Coronado GD, Thompson B, Griffith WC. Children's exposure to OP pesticides:response to Fenske et al. Environmental Health Perspectives 2004;112(15):A866 (correspondence). |
R831709 (2005) R831709C003 (2005) |
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| Journal Article | Coronado GD, Thompson B, Griffith WC. Children's exposure to OP pesticides: response to Fenske et al. Environmental Health Perspectives 2004;112(15):A866-A866. |
R831709 (2007) |
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| Journal Article | Coronado GD, Thompson B, Strong L, Griffith WC, Islas I. Activities and organophosphate exposures: response. Environmental Health Perspectives 2004;112(13):A725-A726 (correspondence). |
R831709 (2005) R831709 (2007) R831709C003 (2005) |
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| Journal Article | Coronado GD, Vigoren EM, Thompson B, Griffith WC, Faustman EM. Organophosphate pesticide exposure and work in pome fruit:evidence for the take-home pesticide pathway. Environmental Health Perspectives 2006;114(7):999-1006. |
R831709 (2005) R831709 (2007) R831709 (Final) R831709C003 (2006) |
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| Journal Article | Coronado GD, Vigoren EM, Griffith WC, Faustman EM, Thompson B. Organophosphate pesticide exposure among pome and non-pome farmworkers:a subgroup analysis of a community randomized trial. Journal of Occupational and Environmental Medicine 2009;51(4):500-509. |
R831709 (2007) R831709 (Final) R832734 (Final) R834514 (2011) R834514 (Final) R834514C001 (Final) |
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| Journal Article | Coronado GD, Griffith WC, Vigoren EM, Faustman EM, Thompson B. Where's the dust? Characterizing locations of azinphos-methyl residues in house and vehicle dust among farmworkers with young children. Journal of Occupational and Environmental Hygiene 2010;7(12):663-671. |
R831709 (Final) R834514 (2011) R834514 (2012) R834514 (2013) R834514 (Final) R834514C001 (Final) |
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| Journal Article | Coronado GD, Holte S, Vigoren E, Griffith WC, Faustman E, Thompson B. Organophosphate pesticide exposure and residential proximity to nearby fields:evidence for the drift pathway. Journal of Occupational and Environmental Medicine 2011;53(8):884-891. |
R831709 (Final) R834514 (2011) R834514 (2012) R834514 (2013) R834514 (Final) R834514C001 (Final) |
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| Journal Article | Costa LG, Richter RJ, Li W-F, Cole T, Guizzetti M, Furlong CE. Paraoxonase (PON1) as a biomarker of susceptibility for organophosphate toxicity. Biomarkers 2003;8(1):1-12. |
R826886 (2000) R826886C002 (2002) R831709 (2005) R831709 (2007) R831709 (Final) R831709C002 (2004) |
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| Journal Article | Costa LG, Cole TB, Jarvik GP, Furlong CE. Functional genomics of the paraoxonase (PON1) polymorphisms: effects on pesticide sensitivity, cardiovascular disease, and drug metabolism. Annual Review of Medicine 2003;54:371-392. |
R826886 (2000) R826886C002 (2002) R831709 (2005) R831709 (2007) R831709 (Final) R831709C002 (2004) |
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| Journal Article | Costa LG, Cole TB, Furlong CE. Polymorphisms of paraoxonase (PON1) and their significance in clinical toxicology of organophosphates. Clinical Toxicology 2003;41(1):37-45. |
R831709 (2005) R831709 (2007) R831709 (Final) R831709C002 (2004) |
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| Journal Article | Costa LG, Aschner M, Vitalone A, Syversen T, Soldin OP. Developmental neuropathology of environmental agents. Annual Review of Pharmacology and Toxicology 2004;44:87-110. |
R831709 (2005) R831709 (2007) R831709 (Final) |
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| Journal Article | Costa LG, Vitalone A, Cole TB, Furlong CE. Modulation of paraoxonase (PON1) activity. Biochemical Pharmacology 2005;69(4):541-550. |
R831709 (2005) R831709 (2007) R831709 (Final) R831709C002 (2004) |
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| Journal Article | Costa LG, Cole TB, Vitalone A, Furlong CE. Measurement of paraoxonase (PON1) status as a potential biomarker of susceptibility to organophosphate toxicity. Clinica Chimica Acta 2005;352(1-2):37-47. |
R831709 (2005) R831709 (2007) R831709 (Final) R831709C002 (2004) |
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| Journal Article | Costa LG, Cole TB, Furlong CE. Paraoxonase (PON1): from toxicology to cardiovascular medicine. Acta Biomedica 2005;76(Suppl 2):50-57. |
R831709 (2005) R831709 (Final) |
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| Journal Article | Costa LG. Current issues in organophosphate toxicology. Clinica Chimica Acta 2006;366(1-2):1-13. |
R831709 (2005) R831709 (2006) R831709 (2007) R831709 (Final) R831709C001 (2006) |
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| Journal Article | Costa LG, Cole TB, Furlong CE. Gene-environment interactions:paraoxonase (PON1) and sensitivity to organophosphate toxicity. LabMedicine 2006;37(2):109-113. |
R831709 (2005) R831709 (2007) R831709 (Final) R831709C001 (2007) R831709C002 (2007) |
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| Journal Article | Costa LG, Giordano G, Guizzetti M, Vitalone A. Neurotoxicity of pesticides: a brief review. Frontiers in Bioscience 2008;13(4):1240-1249. |
R831709 (2005) R831709 (2007) R831709 (Final) R831709C001 (2007) R831709C002 (2007) |
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| Journal Article | Costa LG, Giordano G, Furlong CE. Pharmacological and dietary modulators of paraxonase 1 (PON1) activity and expression: the hunt goes on. Biochemical Pharmacology 2011;81(3):337-344. |
R831709 (Final) R834514 (2011) R834514 (2012) R834514 (2013) R834514 (Final) |
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| Journal Article | Cullen AC, Corrales MA, Kramer CB, Faustman EM. The application of genetic information for regulatory standard setting under the clean air act:a decision-analytic approach. Risk Analysis 2008;28(4):877-890. |
R831709 (2007) R831709 (Final) |
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| Journal Article | Curl CL, Fenske RA, Elgethun K. Organophosphorus pesticide exposure of urban and suburban preschool children with organic and conventional diets. Environmental Health Perspectives 2003;111(3):377-382. |
R831709 (2005) R831709 (2007) R831709 (Final) |
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| Journal Article | Daston G, Faustman E, Ginsberg G, Fenner-Crisp P, Olin S, Sonawane B, Bruckner J, Breslin W, McLaughlin TJ. A framework for assessing risks to children from exposure to environmental agents. Environmental Health Perspectives 2004;112(2):238-256. |
R831709 (2007) R831709C001 (2004) |
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| Journal Article | Drew CH, Grace DA, Silbernagel SM, Hemmings ES, Smith A, Griffith WC, Takaro TK, Faustman EM. Nuclear waste transportation:case studies of identifying stakeholder risk information needs. Environmental Health Perspectives 2003;111(3):263-272. |
R831709 (2005) R831709 (2007) R831709 (Final) |
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| Journal Article | Eaton DL, Daroff RB, Autrup H, Bridges J, Buffler P, Costa LG, Coyle J, McKhann G, Mobley WC, Nadel L, Neubert D, Schulte-Hermann R, Spencer PS. Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment. Critical Reviews in Toxicology 2008;38(Supplement 2):1-125. |
R831709 (2007) R831709 (Final) |
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| Journal Article | Elgethun K, Fenske RA, Yost MG, Palcisko GJ. Time-location analysis for exposure assessment studies of children using a novel global positioning system instrument. Environmental Health Perspectives 2003;111(1):115-122. |
R826886 (2000) R826886C004 (2002) R831709 (2005) R831709 (2007) R831709 (Final) |
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| Journal Article | Elgethun K, Yost MG, Fitzpatrick CTE, Nyerges TL, Fenske RA. Comparison of global positioning system (GPS) tracking and parent-report diaries to characterize children's time-location patterns. Journal of Exposure Science and Environmental Epidemiology 2007;17(2):196-206. |
R831709 (2005) R831709 (2006) R831709 (2007) R831709 (Final) R831709C004 (2006) R831709C004 (2007) |
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| Journal Article | Eskenazi B, Harley K, Bradman A, Weltzien E, Jewell NP, Barr DB, Furlong CE, Holland NT. Association of in utero organophosphate pesticide exposure and fetal growth and length of gestation in an agricultural population. Environmental Health Perspectives 2004;112(10):1116-1124. |
R831709 (2007) R831709 (Final) R831709C002 (2004) R831710 (2004) R831710 (2005) R831710 (Final) R831710C001 (2004) |
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| Journal Article | Eskenazi B, Gladstone EA, Berkowitz GS, Drew CH, Faustman EM, Holland NT, Lanphear B, Meisel SJ, Perera FP, Rauh VA, Sweeney A, Whyatt RM, Yolton K. Methodologic and logistic issues in conducting longitudinal birth cohort studies: lessons learned from the Centers for Children's Environmental Health and Disease Prevention Research. Environmental Health Perspectives 2005;113(10):1419-1429. |
R827027 (2002) R829389 (2003) R829389 (2004) R829389 (2005) R829389 (Final) R829390 (2005) R829390 (Final) R829390C002 (2005) R831709 (2005) R831709 (Final) R831709C001 (2004) R831710 (2005) R831710 (Final) R831710C001 (2006) R831710C002 (2006) R831711 (2005) R831711 (2006) R831711 (2007) R831711 (Final) R831711C001 (2006) R831711C002 (2004) R831711C002 (2006) R831711C003 (2006) R832141 (2005) R832141 (2007) R832141 (Final) |
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| Journal Article | Faustman EM, Gohlke J, Judd NL, Lewandowski TA, Bartell SM, Griffith WC. Modeling developmental processes in animals:applications in neurodevelopmental toxicology. Environmental Toxicology and Pharmacology 2005;19(3):615-624. |
R831709 (2005) R831709 (2006) R831709 (2007) R831709 (Final) R831709C001 (2004) R831709C001 (2005) R831709C001 (2006) |
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| Journal Article | Fenske RA, Lu C, Curl CL, Shirai JH, Kissel JC. Biologic monitoring to characterize organophosphorus pesticide exposure among children and workers:an analysis of recent studies in Washington State. Environmental Health Perspectives 2005;113(11):1651-1657. |
R831709 (2005) R831709 (2007) R831709 (Final) |
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| Journal Article | Fenske RA, Bradman A, Whyatt RM, Wolff MS, Barr DB. Lessons learned for the assessment of children's pesticide exposure: critical sampling and analytical issues for future studies. Environmental Health Perspectives 2005;113(10):1455-1462. |
R827027 (2002) R831709 (2005) R831709 (2007) R831709 (Final) R831710 (2004) R831710 (2005) R831710 (Final) R831711 (2004) R831711 (2005) R831711 (2006) R831711 (2007) R831711 (Final) R831711C001 (2006) R831711C002 (2006) R831711C003 (2006) R832141 (2006) R832141 (2007) R832141 (Final) |
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| Journal Article | Furlong CE, Cole TB, Jarvik GP, Pettan-Brewer C, Geiss GK, Richter RJ, Shih DM, Tward AD, Lusis AJ, Costa LG. Role of paraoxonase (PON1) status in pesticide sensitivity:genetic and temporal determinants. Neurotoxicology 2005;26(4):651-659. |
R831709 (2005) R831709 (2007) R831709 (Final) R831709C002 (2004) |
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| Journal Article | Furlong CE, Cole TB, Walter BJ, Shih DM, Tward A, Lusis AJ, Timchalk C, Richter RJ, Costa LG. Paraoxonase 1 (PON1) status and risk of insecticide exposure. Journal of Biochemical and Molecular Toxicology 2005;19(3):182-183. |
R831709 (2005) R831709 (2007) R831709 (Final) R831709C002 (2005) |
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| Journal Article | Furlong CE, Holland N, Richter RJ, Bradman A, Ho A, Eskenazi B. PON1 status of farmworker mothers and children as a predictor of organophosphate sensitivity. Pharmacogenetics and Genomics 2006;16(3):183-190. |
R831709 (2005) R831709 (2006) R831709 (2007) R831709 (Final) R831709C002 (2006) R831710 (2004) R831710 (2005) R831710 (Final) R831710C001 (2007) R831710C003 (2006) R831710C003 (2007) |
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| Journal Article | Furlong CE. Genetic variability in the cytochrome P450-paraoxonase 1 (PON1) pathway for detoxication of organophosphorus compounds. Journal of Biochemical and Molecular Toxicology 2007;21(4):197-205. |
R831709 (2005) R831709 (2007) R831709 (Final) |
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| Journal Article | Furlong CE, Suzuki SM, Stevens RC, Marsillach J, Richter RJ, Jarvik GP, Checkoway H, Samii A, Costa LG, Griffith A, Roberts JW, Yearout D, Zabetian CP. Human PON1, a biomarker of risk of disease and exposure. Chemico-Biological Interactions 2010;187(1-3):355-361. |
R831709 (2007) R831709 (Final) R834514 (2011) R834514 (2012) R834514 (2013) |
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| Journal Article | Garry MR, Kavanagh TJ, Faustman EM, Sidhu JS, Liao R, Ware C, Vliet P, Deeb S. Sensitivity of mouse lung fibroblasts heterozygous for GPx4 to oxidative stress. Free Radical Biology and Medicine 2008;44(6):1075-1087. |
R831709 (2005) R831709 (2007) R831709 (Final) |
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| Journal Article | Giordano G, Afsharinejad Z, Guizzetti M, Vitalone A, Kavanagh TJ, Costa LG. Organophosphorus insecticides chlorpyrifos and diazinon and oxidative stress in neuronal cells in a genetic model of glutathione deficiency. Toxicology and Applied Pharmacology 2007;219(2-3):181-189. |
R831709 (2005) R831709 (2006) R831709 (2007) R831709 (Final) R831709C001 (2006) R831709C001 (2007) R831709C002 (2007) |
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| Journal Article | Giordano G, Pizzurro D, VanDeMark KL, Guizzetti M, Costa LG. Manganese inhibits the ability of astrocytes to promote neuronal differentiation. Toxicology and Applied Pharmacology 2009; 240(2):226-235. |
R831709 (2007) R831709 (Final) |
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| Journal Article | Gohlke JM, Griffith WC, Faustman EM. The role of cell death during neocortical neurogenesis and synaptogenesis:implications from a computational model for the rat and mouse. Developmental Brain Research 2004;151(1-2):43-54. |
R831709 (2005) R831709 (2007) R831709 (Final) R831709C001 (2004) |
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| Journal Article | Gohlke JM, Griffith WC, Faustman EM. A systems-based computational model for dose-response comparisons of two mode of action hypotheses for ethanol-induced neurodevelopmental toxicity. Toxicological Sciences 2005;86(2):470-484. |
R831709 (2004) R831709 (2005) R831709 (2007) R831709 (Final) R831709C001 (2005) |
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| Journal Article | Gohlke JM, Griffith WC, Faustman EM. Computational models of neocortical neuronogenesis and programmed cell death in the developing mouse, monkey, and human. Cerebral Cortex 2007;17(10):2433-2442. |
R831709 (2005) R831709 (2007) R831709 (Final) |
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| Journal Article | Gohlke JM, Griffith WC, Faustman EM. Computational models of ethanol-induced neurodevelopmental toxicity across species:implications for risk assessment. Birth Defects Research Part B. Developmental and Reproductive Toxicology 2008;83(1):1-11. |
R831709 (2007) R831709 (Final) |
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| Journal Article | Gribble EJ, Hong SW, Faustman EM. The magnitude of methylmercury-induced cytotoxicity and cell cycle arrest is p53-dependent. Birth Defects Research Part A:Clinical and Molecular Teratology 2005;73(1):29-38. |
R831709 (2005) R831709 (2007) R831709 (Final) R831709C001 (2004) |
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| Journal Article | Griffith W, Curl CL, Fenske RA, Lu CA, Vigoren EM, Faustman EM. Organophosphate pesticide metabolite levels in pre-school children in an agricultural community:within-and between-child variability in a longitudinal study. Environmental Research 2011;111(6):751-756. |
R831709 (Final) R834514 (2011) R834514 (2012) R834514 (2013) R834514 (Final) R834514C002 (Final) |
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| Journal Article | Guizzetti M, Pathak S, Giordano G, Costa LG. Effect of organophosphorus insecticides and their metabolites on astroglial cell proliferation. Toxicology 2005;215(3):182-190. |
R831709 (2005) R831709 (2006) R831709 (2007) R831709 (Final) R831709C001 (2005) R831709C001 (2006) R831709C002 (2006) |
|
| Journal Article | Guizzetti M, Moore NH, Giordano G, Costa LG. Modulation of neuritogenesis by astrocyte muscarinic receptors. Journal of Biological Chemistry 2008;283(46):31884-31897. |
R831709 (2007) R831709 (Final) |
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| Journal Article | Guizzetti M, Moore NH, Giordano G, VanDeMark KL, Costa LG. Ethanol inhibits neuritogenesis induced by astrocyte muscarinic receptors. Glia 2010;58(12):1395-1406. |
R831709 (2007) R831709 (Final) R834514 (2011) R834514 (2012) R834514 (2013) |
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| Journal Article | Hetman M, Hsuan SL, Habas A, Higgins MJ, Xia Z. ERK1/2 antagonizes glycogen synthase kinase-3beta-induced apoptosis in cortical neurons. Journal of Biological Chemistry 277(51):49577-49584. |
R831709 (2005) R831709 (2007) |
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| Journal Article | Hofmann JN, Keifer MC, Furlong CE, De Roos AJ, Farin FM, Fenske RA, van Belle G, Checkoway H. Serum cholinesterase inhibition in relation to paraoxonase-1 (PON1) status among organophosphate-exposed agricultural pesticide handlers. Environmental Health Perspectives 2009;117(9):1402-1408. |
R831709 (Final) R834514 (2012) R834514 (2013) |
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| Journal Article | Hofmann JN, Keifer MC, De Roos AJ, Fenske RA, Furlong CE, van Belle G, Checkoway H. Occupational determinants of serum cholinesterase inhibition among organophosphate-exposed agricultural pesticide handlers in Washington State. Occupational and Environmental Medicine 2010;67(6):375-386. |
R831709 (Final) R834514 (2012) R834514 (2013) R834514 (Final) |
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| Journal Article | Holland N, Furlong C, Bastaki M, Richter R, Bradman A, Huen K, Beckman K, Eskenazi B. Paraoxonase polymorphisms, haplotypes, and enzyme activity in Latino mothers and newborns. Environmental Health Perspectives 2006;114(7):985-991. |
R831709 (2005) R831709 (2006) R831709 (2007) R831709 (Final) R831709C002 (2006) R831710 (2004) R831710 (2005) R831710 (Final) R831710C001 (2007) R831710C003 (2006) R832734 (2006) R832734 (2007) R832734 (Final) |
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| Journal Article | Huen K, Richter R, Furlong C, Eskenazi B, Holland N. Validation of PON1 enzyme activity assays for longitudinal studies. Clinica Chimica Acta 2009;402(1-2):67-74. |
R831709 (2007) R831709 (Final) R831710 (Final) R832734 (2009) R832734 (Final) R834513 (2010) R834513 (2011) R834513 (Final) |
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| Journal Article | Israel BA, Parker EA, Rowe Z, Salvatore A, Minkler M, Lopez J, Butz A, Mosley A, Coates L, Lambert G, Potito PA, Brenner B, Rivera M, Romero H, Thompson B, Coronado G, Halstead S. Community-based participatory research:lessons learned from the Centers for Children's Environmental Health and Disease Prevention Research. Environmental Health Perspectives 2005;113(10):1463-1471. |
R826710 (Final) R829391 (2004) R829391 (2005) R829391 (2006) R829391 (Final) R829391C005 (2006) R831709 (2005) R831709 (2007) R831709 (Final) R831709C003 (2005) R831709C003 (2006) R831710 (2004) R831710 (2005) R831710 (Final) R831710C001 (2006) R831710C002 (2006) R831710C004 (2006) R831711 (2005) R831711 (2006) R831711 (2007) R831711 (Final) R831711C001 (2006) R831711C002 (2006) R831711C003 (2006) R832139 (2006) |
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| Journal Article | Jansen KL, Cole TB, Park SS, Furlong CE, Costa LG. Paraoxonase 1 (PON1) modulates the toxicity of mixed organophosphorus compounds. Toxicology and Applied Pharmacology 2009;236(2):142-153. |
R831709 (Final) R834514 (2012) R834514 (2013) R834514 (Final) |
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| Journal Article | Jarvik GP, Jampsa R, Richter RJ, Carlson CS, Rieder MJ, Nickerson DA, Furlong CE. Novel paraoxonase (PON1) nonsense and missense mutations predicted by functional genomic assay of PON1 status. Pharmacogenetics 2003;13(5):291-295. |
R831709 (2005) R831709 (2007) R831709 (Final) R831709C002 (2004) |
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| Journal Article | Judd NL, Griffith WC, Takaro T, Faustman EM. A model for optimization of biomarker testing frequency to minimize disease and cost:example of beryllium sensitization testing. Risk Analysis 2003; 23(6):1211-1220. |
R831709 (2005) R831709 (2007) R831709 (Final) |
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| Journal Article | Judd NL, Karr JR, Griffith WC, Faustman EM. Challenges in defining background levels for human and ecological risk assessments.Human and Ecological Risk Assessment:An International Journal 2003; 9(7):1623-1632. |
R831709 (2005) R831709 (2007) R831709 (Final) |
|
| Journal Article | Judd NL, Griffith WC, Kalman DA, Faustman EM. Assessment of PCB congener analytical methods:do they meet risk assessment needs? Archives of Environmental Contamination and Toxicology 2003; 44(1):132-139. |
R831709 (2005) R831709 (2007) R831709 (Final) |
|
| Journal Article | Judd NL, Griffith WC, Faustman EM. Consideration of cultural and lifestyle factors in defining susceptible populations for environmental disease. Toxicology 2004;198(1-3):121-133. |
R831709 (2005) R831709 (2007) R831709 (Final) |
|
| Journal Article | Judd N, Griffith WC, Faustman EM. Contribution of PCB exposure from fish consumption to total dioxin-like dietary exposure. Regulatory Toxicology and Pharmacology 2004;40(2):125-135. |
R831709 (2005) R831709 (2007) R831709 (Final) |
|
| Journal Article | Kelada SN, Costa-Mallen P, Checkoway H, Viernes HA, Farin FM, Smith-Weller T, Franklin GM, Costa LG, Longstreth Jr WT, Furlong CE, Javrik GP, Swanson PD. Paraoxonase 1 promoter and coding region polymorphisms in Parkinson's disease. Journal of Neurology, Neurosurgery, and Psychiatry 2003;74(4):546-547. |
R831709 (2005) R831709 (2007) R831709 (Final) R831709C002 (2004) |
|
| Journal Article | Kelada SN, Stapleton PL, Farin FM, Bammler TK, Eaton DL, Smith-Weller T, Franklin GM, Swanson PD, Longstreth Jr WT, Checkoway H. Glutathione S-transferase M1, T1, and P1 polymorphisms and Parkinson's disease. Neuroscience Letters 2003;337(1):5-8. |
R831709 (2005) R831709 (2007) R831709 (Final) |
|
| Journal Article | Kim JH, Stevens RC, MacCoss MJ, Goodlett DR, Scherl A, Richter RJ, Suzuki SM, Furlong CE. Identification and characterization of biomarkers of organophosphorus exposures in humans. Advances in Experimental Medicine and Biology 2010;660:61-71. |
R831709 (Final) R834514 (2011) R834514 (2012) R834514 (2013) R834514 (Final) |
|
| Journal Article | Kissel JC, Curl CL, Kedan G, Lu C, Griffith W, Barr DB, Needham LL, Fenske RA. Comparison of organophosphorus pesticide metabolite levels in single and multiple daily urine samples collected from preschool children in Washington State. Journal of Exposure Analysis and Environmental Epidemiology 2005;15(2):164-171. |
R831709 (2005) R831709 (2007) |
|
| Journal Article | Koo B, Gaydos TM, Pandis SN. Evaluation of the equilibrium, dynamic, and hybrid aerosol modeling approaches. Aerosol Science and Technology 2003;37(1):53-64. |
R826371 (Final) R826371C005 (Final) R831709 (2007) R831709C003 (2004) |
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| Journal Article | Lanktree MB, Guo Y, Murtaza M, Glessner JT, Bailey SD, Onland-Moret NC, Lettre G, Ongen H, Rajagopalan R, Johnson T, Shen H, Nelson CP, Klopp N, Baumert J, Padmanabhan S, Pankratz N, Pankow JS, Shah S, Taylor K, Barnard J, Peters BJ, Maloney CM, Lobmeyer MT, Stanton A, Zafarmand MH, Romaine SP, Mehta A, van Iperen EP, Gong Y, Price TS, Smith EN, Kim CE, Li YR, Asselbergs FW, Atwood LD, Bailey KM, Bhatt D, Bauer F, Behr ER, Bhangale T, Boer JM, Boehm BO, Bradfield JP, Brown M, Braund PS, et al. Meta-analysis of dense genecentric association studies reveals common and uncommon variants associated with height. American Journal of Human Genetics 2011;88(1):6-18. |
R831709 (Final) R834514 (2011) R834514 (Final) |
|
| Journal Article | Latowsky G. Report: Community-based, participatory research in Lawrence, Massachusetts, flags environmental health hazards and fuels education and action. Science Communication 2003;25(2):204-208. |
R828596 (2004) R831709 (2006) R831709 (2007) |
|
| Journal Article | Lewandowski TA, Ponce RA, Charleston JS, Hong S, Faustman EM. Changes in cell cycle parameters and cell number in the rat midbrain during organogenesis. Developmental Brain Research 2003;141(1-2):117-128. |
R831709 (2005) R831709 (2007) R831709 (Final) R831709C001 (2004) |
|
| Journal Article | Lewandowski TA, Ponce RA, Charleston JS, Hong S, Faustman EM. Effect of methylmercury on midbrain cell proliferation during organogenesis:potential cross-species differences and implications for risk assessment. Toxicological Sciences 2003;75(1):124-133. |
R831709 (2005) R831709 (2007) R831709 (Final) R831709C001 (2004) |
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| Journal Article | Livaudais JC, Thompson B, Islas I, Ibarra G, Anderson J, Coronado GD. Workplace exposures and protective practices of Hispanic warehouse workers. Journal of Immigrant and Minority Health 2009;11(2):122-130. |
R831709 (2007) R831709 (Final) |
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| Journal Article | Locke E, Coronado GD, Thompson B, Kuniyuki A. Seasonal variation in fruit and vegetable consumption in a rural agricultural community. Journal of the American Dietetic Association 2009;109(1):45-51. |
R831709 (2007) R831709 (Final) |
|
| Journal Article | Luderer U, Diaz D, Faustman EM, Kavanagh TJ. Localization of glutamate cysteine ligase subunit mRNA within the rat ovary and relationship to follicular apoptosis. Molecular Reproduction and Development 2003;65(3):254-261. |
R831709 (2005) R831709 (2007) R831709 (Final) |
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| Journal Article | Mackenzie-Ross SJ, Brewin CR, Curran HV, Furlong CE, Abraham-Smith KM, Harrison V. Neuropsychological and psychiatric functioning in sheep farmers exposed to low levels of organophosphate pesticides. Neurotoxicology and Teratology 2010;32(4):452-459. |
R831709 (Final) R834514 (2011) R834514 (2012) R834514 (2013) R834514 (Final) |
|
| Journal Article | Moreira EG, Yu X., Robinson JF, Griffith W, Hong SW, Beyer RP, Bammler TK, Faustman EM. Toxicogenomic profiling in maternal and fetal rodent brains following gestational exposure to chlorpyrifos. Toxicology and Applied Pharmacology 2010;245(3):310-325. |
R831709 (2007) R831709 (Final) R834514 (2011) R834514 (2012) R834514 (2013) R834514 (Final) R834514C003 (Final) |
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| Journal Article | Postma J, Karr C, Kieckhefer G. Community health workers and environmental interventions for children with asthma: a systematic review. Journal of Asthma 2009;46(6):564-576. |
R831709 (Final) R834514 (2012) R834514 (2013) R834514 (Final) |
|
| Journal Article | Ramaprasad J, Tsai M-Y, Elgethun K, Hebert VR, Felsot A, Yost MG, Fenske RA. The Washington aerial spray drift study: assessment of off-target organophosphorus insecticide atmospheric movement by plant surface volatilization. Atmospheric Environment 2004;38(33):5703-5713. |
R831709 (2005) R831709 (2007) R831709 (Final) R831709C004 (2004) |
|
| Journal Article | Ramaprasad J, Tsai MG, Fenske RA, Faustman EM, Griffith WC, Felsot AS, Elgethun K, Weppner S, Yost MG. Children's inhalation exposure to methamidophos from sprayed potato fields in Washington State:exploring the use of probabilistic modeling of meteorological data in exposure assessment. Journal of Exposure Science and Environmental Epidemiology 2009;19(6):613-623. |
R831709 (2007) R831709 (Final) R834514 (Final) R834514C002 (Final) |
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| Journal Article | Richter RJ, Jampsa RL, Jarvik GP, Costa LG, Furlong CE. Determination of paraoxonase 1 status and genotypes at specific polymorphic sites. Current Protocols in Toxicology 2004;19(1):4. |
R831709 (2007) R831709 (Final) |
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| Journal Article | Richter RJ, Jarvik GP, Furlong CE. Determination of paraoxonase (PON1) status without the use of toxic organophosphate substrates. Circulation: Cardiovascular Genetics 2008;1(2):147-152. |
R831709 (2007) R831709 (Final) |
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| Journal Article | Richter RJ, Jarvik GP, Furlong CE. Paraoxonase 1 (PON1) status and substrate hydrolysis. Toxicology and Applied Pharmacology 2009;235(1):1-9. |
R831709 (2007) R831709 (Final) R834514 (2012) R834514 (2013) R834514 (Final) |
|
| Journal Article | Richter RJ, Jarvik GP, Furlong CE. Paraoxonase 1 (PON1) status as a risk factor for disease or exposure. Advances in Experimental Medicine and Biology 2010;660:29-35. |
R831709 (2007) R831709 (Final) |
|
| Journal Article | Robinson JF, Yu X, Hong S, Griffith WC, Beyer R, Kim E, Faustman EM. Cadmium-induced differential toxicogenomic response in resistant and sensitive mouse strains undergoing neurulation. Toxicological Sciences 2009;107(1):206-219. |
R831709 (2007) R831709 (Final) |
|
| Journal Article | Robinson JF, Guerrette Z, Yu X, Hong S, Faustman EM. A systems-based approach to investigate dose-and time-dependent methylmercury-induced gene expression response in C57BL/6 mouse embryos undergoing neurulation. Birth Defects Research. Part B: Developmental and Reproductive Toxicology 2010;89(3):188-200. |
R831709 (Final) R834514 (2011) R834514 (2012) R834514 (2013) R834514 (Final) R834514C003 (Final) |
|
| Journal Article | Robinson JF, Yu X, Hong S, Zhou C, Kim N, DeMasi D, Faustman EM. Embryonic toxicokinetic and dynamic differences underlying strain sensitivity to cadmium during neurulation. Reproductive Toxicology 2010;29(3):279-285. |
R831709 (2007) R831709 (Final) R834514 (2011) R834514 (2012) R834514 (2013) |
|
| Journal Article | Robinson JF, Port JA, Yu X, Faustman EM. Integrating genetic and toxicogenomic information for determining underlying susceptibility to developmental disorders. Birth Defects Research. Part A--Clinical and Molecular Teratology 2010;88(10):920-930. |
R831709 (Final) R834514 (2011) R834514 (2012) R834514 (2013) R834514 (Final) |
|
| Journal Article | Robinson JF, Griffith WC, Yu X, Hong S, Kim E, Faustman EM. Methylmercury induced toxicogenomic response in C57 and SWV mouse embryos undergoing neural tube closure. Reproductive Toxicology 2010;30(2):284-291. |
R831709 (Final) R834514 (2011) R834514 (2012) R834514 (2013) R834514 (Final) R834514C003 (Final) |
|
| Journal Article | Robinson JF, Yu X, Moreira EG, Hong S, Faustman EM. Arsenic-and cadmium-induced toxicogenomic response in mouse embryos undergoing neurulation. Toxicology and Applied Pharmacology 2011;250(2):117-129. |
R831709 (Final) R834514 (2011) R834514 (2012) R834514 (2013) R834514 (Final) R834514C003 (Final) |
|
| Journal Article | Schopfer LM, Furlong CE, Lockridge O. Development of diagnostics in the search of an explanation of aerotoxic syndrome. Analytical Biochemistry 2010;404(1):64-74. |
R831709 (Final) R834514 (2011) R834514 (2012) R834514 (2013) R834514 (Final) |
|
| Journal Article | Sidhu JS, Ponce RA, Vredevoogd MA, Yu X, Gribble E, Hong S-W, Schneider E, Faustman EM. Cell cycle inhibition by sodium arsenite in primary embryonic rat midbrain neuroepithelial cells. Toxicological Sciences 2006;89(2):475-484. |
R831709 (2005) R831709 (2006) R831709 (2007) R831709 (Final) R831709C001 (2005) R831709C001 (2006) |
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| Journal Article | Snipes SA, Thompson B, O’Connor K, Godina R, Ibarra G. Anthropological and psychological merge:design of a stress measure for Mexican farmworkers. Culture Medicine and Psychiatry 2007;31(3):359-388. |
R831709 (2005) R831709 (2007) R831709 (Final) |
|
| Journal Article | Stevens RC, Soelberg SD, Eberhart BT, Spencer S, Wekell JC, Chinowsky TM, Trainer VL, Furlong CE. Detection of the toxin domoic acid from clam extracts using a portable surface plasmon resonance biosensor. Harmful Algae 2007;6(2):166-174. |
R831709 (2005) R831709 (2007) R831709 (Final) |
|
| Journal Article | Stevens RC, Suzuki SM, Cole TB, Park SS, Richter RJ, Furlong CE. Engineered recombinant human paraoxonase 1 (rHUPON1) purified from Escherichia coli protects against organophosphate poisoning. Proceedings of the National Academy of Sciences of the United States of America 2008;105(35):12780-12784. |
R831709 (2007) R831709 (Final) |
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| Journal Article | Strong LL, Thompson B, Coronado GD, Griffith WC, Vigoren EM, Islas I. Health symptoms and exposure to organophosphate pesticides in farmworkers. American Journal of Industrial Medicine 2004;46(6):599-606. |
R831709 (2005) R831709 (2007) R831709 (Final) R831709C003 (2004) |
|
| Journal Article | Strong LL, Thompson B, Koepsell TD, Meischke H. Factors associated with pesticide safety practices in farmworkers. American Journal of Industrial Medicine 2008;51(1):69-81. |
R831709 (2005) R831709 (2006) R831709 (2007) R831709 (Final) R831709C003 (2006) R831709C003 (2007) R832740 (Final) |
|
| Journal Article | Strong LL, Thompson B, Koepsell TD, Meischke H, Coronado GD. Reducing the take-home pathway of pesticide exposure:behavioral outcomes from the Para Niños Saludables study. Journal of Occupational and Environmental Medicine 2009;51(8):922-933. |
R831709 (2007) R831709 (Final) R834514 (Final) R834514C001 (Final) |
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| Journal Article | Suzuki SM, Stevens RC, Richter RJ, Cole TB, Park S, Otto TC, Cerasoli DM, Lenz DE, Furlong CE. Engineering human PON1 in an E. coli expression system. Advances in Experimental Medicine and Biology 2010;660:37-45. |
R831709 (2007) R831709 (Final) R834514 (2011) R834514 (2012) R834514 (2013) |
|
| Journal Article | Thompson B, Coronado GD, Grossman JE, Puschel K, Solomon CC, Islas I, Curl CL, Shirai JH, Kissel JC, Fenske RA. Pesticide take-home pathway among children of agricultural workers: study design, methods, and baseline findings. Journal of Occupational and Environmental Medicine 2003;45(1):42-53. |
R826886 (2000) R826886C003 (2002) R831709 (2005) R831709 (2007) R831709 (Final) R831709C003 (2004) |
|
| Journal Article | Thompson B, Coronado GD, Vigoren EM, Griffith WC, Fenske RA, Kissel JC, Shirai JH, Faustman EM. Para niños saludables:a community intervention trial to reduce organophosphate pesticide exposure in children of farmworkers.Environmental Health Perspectives 2008;116(5):687-694. |
R831709 (2005) R831709 (2007) R831709 (Final) R831709C003 (2007) |
|
| Journal Article | Ticozzi N, LeClerc AL, Keagle PJ, Glass JD, Wills AM, van Blitterswijk M, Bosco DA, Rodriguez-Levva I, Gellera C, Ratti A, Taroni F, McKenna-Yasek D, Sapp PC, Silani V, Furlong CE, Brown Jr. RH, Landers JE. Paraoxonase gene mutations in amyotrophic lateral sclerosis. Annals of Neurology 2010;68(1):102-107. |
R831709 (Final) R834514 (2011) R834514 (2012) R834514 (2013) R834514 (Final) |
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| Journal Article | Tiffany-Castiglioni E, Venkratraj V, Qian Y. Genetic polymorphisms and mechanisms of neurotoxicity:overview. Neurotoxicology 2005;26(4):641-649. |
R831709 (2007) R831709C002 (2004) |
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| Journal Article | Tsai M-Y, Elgethun K, Ramaprasad J, Yost MG, Felsot AS, Hebert VR, Fenske RA. The Washington aerial spray drift study: modeling pesticide spray drift deposition from an aerial application. Atmospheric Environment 2005;39(33):6194-6203. |
R831709 (2005) R831709 (2007) R831709 (Final) R831709C004 (2005) R831709C004 (2006) |
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| Journal Article | VanDeMark KL, Guizzetti M, Giordano G, Costa LG. The activation of M1 muscarinic receptor signaling induces neuronal differentiation in pyramidal hippocampal neurons. Journal of Pharmacology and Experimental Therapeutics 2009;329(2):532-542. |
R831709 (2007) R831709 (Final) |
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| Journal Article | VanDeMark KL, Guizzetti M, Giordano G, Costa LG. Ethanol inhibits muscarinic receptor-induced axonal growth in rat hippocampal neurons. Alcoholism, Clinical and Experimental Research 2009; 33(11):1945-1955. |
R831709 (2007) R831709 (Final) |
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| Journal Article | Weiner MW, Meyerhoff DJ, Neylan TC, Hlavin J, Ramage ER, McCoy D, Studholme C, Cardenas V, Marmar C, Truran D, Chu PW, Kornak J, Furlong CE, McCarthy C. The relationship between Gulf War war illness, brain N-acetylaspartate, and post-traumatic stress disorder. Military Medicine 2011;176(8):896-902. |
R831709 (Final) R834514 (2011) R834514 (2012) R834514 (2013) R834514 (Final) |
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| Journal Article | Weppner S, Elgethun K, Lu C, Herbert V, Yost MG, Fenske RA. The Washington aerial spray drift study:children's exposure to methamidophos in an agricultural community following fixed-wing aircraft applications. Journal of Exposure Science and Environmental Epidemiology 2006;16(5):387-396. |
R831709 (2005) R831709 (2006) R831709 (2007) R831709 (Final) R831709C004 (2006) R831709C004 (2007) |
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| Journal Article | Wills AM, Landers JE, Zhang H, Richter RJ, Caraganis AJ, Cudkowicz ME, Furlong CE, Brown Jr. RH. Paraoxonase 1 (PON1) organophosphate hydrolysis is not reduced in ALS. Neurology 2008;70(12):929-934. |
R831709 (2007) R831709 (Final) |
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| Journal Article | Wong EY, Ponce RA, Farrow S, Bartell SM, Lee RC, Faustman EM. Comparative risk and policy analysis in environmental health. Risk Analysis 2003;23(6):1337-1349. |
R831709 (2005) R831709 (2007) R831709 (Final) |
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| Journal Article | Wong EY, Gohlke J, Griffith WC, Farrow S, Faustman EM. Assessing the health benefits of air pollution reduction for children. Environmental Health Perspectives 2004;112(2):226-232. |
R831709 (2005) R831709 (2007) R831709 (Final) |
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| Journal Article | Young JG, Eskenazi B, Gladstone EA, Bradman A, Pedersen L, Johnson C, Barr DB, Furlong CE, Holland NT. Association between in utero organophosphate pesticide exposure and abnormal reflexes in neonates. NeuroToxicology 2005;26(2):199-209. |
R831709 (2005) R831709 (2006) R831709 (2007) R831709 (Final) R831709C002 (2004) R831709C002 (2006) R831710 (2004) R831710 (2005) R831710 (Final) |
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| Journal Article | Yu X, Sidhu JS, Hong S, Faustman EM. Essential role of extracellular matrix (ECM) overlay in establishing the functional integrity of primary neonatal rat Sertoli cell/gonocyte co-cultures:an improved in vitro model for assessment of male reproductive toxicity. Toxicological Sciences 2005;84(2):378-393. |
R831709 (2005) R831709 (2007) R831709 (Final) |
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| Journal Article | Yu X, Griffith WC, Hanspers K, Dillman III JF, Ong H, Vredevoogd MA, Faustman EM. A system-based approach to interpret dose-and time-dependent microarray data:quantitative integration of gene ontology analysis for risk assessment. Toxicological Sciences 2006;92(2):560-577. |
R831709 (2005) R831709 (2006) R831709 (2007) R831709 (Final) R831709C001 (2006) R832733 (2007) |
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| Journal Article | Yu X, Hong S, Faustman EM. Cadmium-induced activation of stress signaling pathways, disruption of ubiquitin-dependent protein degradation and apoptosis in primary rat Sertoli cell-gonocyte cocultures. Toxicological Sciences 2008;104(2):385-396. |
R831709 (2007) R831709 (Final) |
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| Journal Article | Yu X, Robinson JF, Gribble E, Hong SW, Sidhu JS, Faustman EM. Gene expression profiling analysis reveals arsenic-induced cell cycle arrest and apoptosis in p53-proficient and p53-deficient cells through differential gene pathways. Toxicology and Applied Pharmacology 2008;233(3):389-403. |
R831709 (2007) R831709 (Final) |
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| Journal Article | Yu X, Hong S, Moreira EG, Faustman EM. Improving in vitro Sertoli cell/gonocyte co-culture model for assessing male reproductive toxicity:lessons learned from comparisons of cytotoxicity versus genomic responses to phthalates. Toxicology and Applied Pharmacology 2009;239(3):325-336. |
R831709 (2007) R831709 (Final) |
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| Journal Article | Yu X, Robinson JF, Sidhu JS, Hong S, Faustman EM. A system-based comparison of gene expression reveals alterations in oxidative stress, disruption of ubiquitin-proteasome system and altered cell cycle regulation after exposure to cadmium and ethylmercury in mouse embryonic fibroblast. Toxicological Sciences 2010;114(2):356-377. |
R831709 (2007) R831709 (Final) R834514 (2011) R834514 (2012) R834514 (2013) R834514 (Final) R834514C003 (Final) |
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| Journal Article | Yu X, Sidhu JS, Hong S, Robinson JF, Ponce RA, Faustman EM. Cadmium induced p53-dependent activation of stress signaling, accumulation of ubiquitinated proteins, and apoptosis in mouse embryonic fibroblast cells. Toxicological Sciences 2011;120(2):403-412. |
R831709 (Final) R834514 (2011) R834514 (2012) R834514 (2013) R834514 (Final) |
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| Journal Article | Jarvik GP, Hatsukami TS, Carlson C, Richter RJ, Jampsa R, Brophy VH, Margolin S, Rieder M, Nickerson D, Schellenberg GD, Heagerty PJ. Paraoxonase activity, but not haplotype utilizing the linkage disequilibrium structure, predicts vascular disease. Arteriosclerosis, Thrombosis, and Vascular Biology 2003;23(8):1465-1471. |
R831709 (Final) |
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| Journal Article | Zurich MG, Honegger P, Schilter B, Costa LG, Monnet-Tschudi F. Involvement of glial cells in the neurotoxicity of parathion and chlorpyrifos. Toxicology and Applied Pharmacology 2004;201(2):97-104. |
R831709 (Final) |
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| Journal Article | Costa LG, Guizzetti M, Vitalone A. Diet–brain connections:role of neurotoxicants. Environmental Toxicology and Pharmacology 2005;19(3):395-400. |
R831709 (Final) |
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| Journal Article | Judd NL, Drew CH, Acharya C, Mitchell TA, Donatuto JL, Burns GW, Burbacher TM, Faustman EM. Framing scientific analyses for risk management of environmental hazards by communities:case studies with seafood safety issues. Environmental Health Perspectives 2005;113(11):1502-1508. |
R831709 (Final) |
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| Journal Article | Ozer EA, Pezzulo A, Shih DM, Chun C, Furlong C, Lusis AJ, Greenberg EP, Zabner J. Human and murine paraoxonase 1 are host modulators of Pseudomonas aeruginosa quorum-sensing. FEMS Microbiology Letters 2005;253(1):29-37. |
R831709 (Final) |
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| Journal Article | Snipes SA, Thompson B, O'Connor K, Shell-Duncan B, King D, Herrera AP, Navarro B. “Pesticides protect the fruit, but not the people”:using community-based ethnography to understand farmworker pesticide-exposure risks. American Journal of Public Health 2009;99(S3):S616-621. |
R831709 (Final) |
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| Journal Article | Louis GB. Principles for evaluating health risks in children associated with exposure to chemicals. World Health Organization; 2006. |
R831709 (Final) |
not available |
| Presentation | Armstrong J, Fenske RA, Yost MG, Galvin K, Tchong-French M, Yu J. Method comparison of polyurethane foam and XAD-2 resin sampling matrices to measure airborne organophosphate pesticides and oxygen analogs. Poster presented at the Joint Annual Conference of the International Society of Exposure Science (ISES) and the International Society for Environmental Epidemiology (ISEE), Seoul, South Korea, August 28-September 1, 2010. |
R831709 (Final) R834514 (2011) R834514 (2012) R834514C002 (Final) |
not available |
| Presentation | Baker PE, Cole TB, Thummel KE, Lin YS, Co AL, Rettie AE, Kim JH, Furlong CE. Identifying less toxic triaryl phosphates for jet engine lubricants. Poster presented at the Society of Toxicology 50th Anniversary Annual Meeting & ToxExpo, Washington, DC, March 6-10, 2011. |
R831709 (Final) R834514 (2011) R834514 (2012) |
not available |
| Presentation | Cole TB, Beyer RP, Bammler TK, Park S, Farin F, Costa LG, Furlong CE. PON1 status modulates cerebellar gene expression changes associated with developmental exposure to chlorpyrifos oxon. Poster presented at the Society of Toxicology 50th Anniversary Annual Meeting & ToxExpo, Washington, DC, March 6-10, 2011. |
R831709 (Final) R834514 (2011) R834514 (2012) |
not available |
| Presentation | Cole TC, Pettan-Brewer C. Modulation of low-level organophosphate toxicity by human PON1, as assessed by microarray analysis. Presented at the Society of Toxicology Annual Meeting, San Diego, CA, March 5-9, 2006. |
R831709 (2005) R831709 (Final) |
not available |
| Presentation | Faustman EM, Yu X, Sidhu JS, Hong S, et al. Integration of toxicogenomic and knowledge-based pathway mapping for elucidating shared molecular mechanisms of metal toxicity. Poster presented at the 10th International Congress of Toxicology, Tampere, Finland, July 11-15, 2004. |
R831709 (Final) R831709C001 (2005) |
not available |
| Presentation | Faustman EM, Yu X, Sidhu J, Robinson J. Toxicant affects on ubiquitin-proteosome systems: lessons from cross-compound and cross-system assessments. Presented at the Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. |
R831709 (Final) R831709C001 (2005) |
not available |
| Presentation | Faustman EM, Yu XZ, Griffith WC. Toxicogenomics: realizing the promise. Presented at the Society for Risk Analysis Annual Meeting, San Antonio, TX, December 9-12, 2007. |
R831709 (Final) |
not available |
| Presentation | Faustman EM. Ten years after the food quality protection act: healthier children or unnecessary burden? Presented at the Society of Toxicology Annual Meeting, Charlotte, NC, March 25-29, 2007. |
R831709 (Final) |
not available |
| Presentation | Faustman EM, Griffith WC. Ins and outs of modeling developmental toxicity data – where are we at and where would we like to be? Presented at the Society for Risk Analysis Annual Meeting, Salt Lake City, UT, December 5-8, 2010. |
R831709 (Final) R834514 (2011) R834514 (2012) |
not available |
| Presentation | Faustman EM. New methodological approaches for understanding and characterizing vulnerability in children's response to organophosphate exposure. Presented at the Pediatric Academic Societies Annual Meeting, Vancouver, British Columbia, Canada, May 1-4, 2010. |
R831709 (Final) R834514 (2011) R834514 (2012) |
not available |
| Presentation | Faustman EM. Gene-environment interactions and children's susceptibility. Presented at the Society of Toxicology 49th Annual Meeting & ToxExpo, Salt Lake City, UT, March 7-11, 2010. |
R831709 (Final) R834514 (2011) R834514 (2012) |
not available |
| Presentation | Faustman E. New risk assessment for protecting susceptible populations. Presented at the 7th Congress of Toxicology in Developing Countries (CTDC-IUTOX), Sun City, South Africa, September 6-9, 2009. |
R831709 (Final) R834514 (2012) |
not available |
| Presentation | Furlong C, Suzuki SM, Stevens RC, Richter RJ, Cole TB, Jarvik GP, Checkoway H, Samii A, Costa LG, Griffith A, Roberts JW, Yearout D, Zabetian CP. Human PON1, a biomarker of risk of disease and exposure. Poster presented at the 10th International Meeting on Cholinesterases, Sibernik, Croatia, September 20-25, 2009. |
R831709 (Final) R834514 (2012) R834514 (2013) |
not available |
| Presentation | Garry MR, Deeb SS, Kavanagh TJ, Yu XZ, Vredevoogd MA, Kim E, Faustman EM. Differential modulation of stress signaling pathways by cadmium in cultured mouse lung fibroblasts heterozygous for gpx4. Presented at the Society of Toxicology Annual Meeting, Charlotte, NC, March 25-29, 2007. |
R831709 (Final) |
not available |
| Presentation | Gohlke JM, Griffith WC, Faustman EM. Computational model for dose-response comparisons of two mechanistic hypotheses for ethanol-induced neurodevelopmental toxicity. Presented at the Society for Risk Analysis 2004 Annual Meeting, Palm Springs, CA, December 5-8, 2004. |
R831709 (Final) R831709C001 (2005) |
not available |
| Presentation | Gohlke JM, Griffith WC, Faustman EM. Computational models for the acquisition of neocortical neurons in the developing humans, monkey, and mouse: cross species comparison of toxicodynamics. Presented at the Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. |
R831709 (Final) R831709C001 (2005) |
not available |
| Presentation | Griffith WC, Yu X, Hanspers K, Dillman III JF, Ong H, Vredevoogd M, Faustman EM. Systems biology evaluation of toxicogenomic microarray data using go-quant to analyze how toxicants alter gene pathways and functional gene categories. Presented at the Society for Risk Analysis Annual Meeting, Baltimore, MD, December 3-6, 2006. |
R831709 (2005) R831709 (Final) |
not available |
| Presentation | Griffith WC, DeFrank MN, Gohlke JM, Gribble EJ, Faustman EM. Systems biology models for integration of diverse studies of the developing neocortex after exposure to low dose radiation from external and internal sources. Presented at the Society of Toxicology Annual Meeting, San Diego, CA, March 5-9, 2006. |
R831709 (Final) |
not available |
| Presentation | Griffith WC. Evaluation of exposure of young children of orchard workers to organophosphate pesticides. Presented at the International Conference on Environmental Epidemiology and Exposure, Paris, France, September 2-6, 2006. |
R831709 (2005) R831709 (Final) |
not available |
| Presentation | Griffith WC, Gohlke JM, Vigoren E, Judd NL, Lewandowski TA, Bartell SM, DeFrank MN, Ramaprasad J, Gribble EJ, Faustman EM. Conceptual framework for linking kinetic and dynamic process in quantitative models describing neurodevelopmental toxicology. Presented at the Joint Conference of the International Society for Environmental Epidemiology and the International Society of Exposure Analysis, Paris, France, September 2-6, 2006. |
R831709 (Final) |
not available |
| Presentation | Griffith WC, Ramaprasad J, Faustman EM. Simulating the effects of polymorphisms and abundance of CYP-450 enzymes in metabolism of chlorpyrifos. Presented at the Society of Risk Analysis Annual Meeting, San Antonio, TX, December 9-12, 2007. |
R831709 (Final) R832733 (2007) |
not available |
| Presentation | Griffith WC, Schumacher KM, Ramapradad J, Faustman EM. Using simple kinetic models to integrate experimental datasets:lessons learned with chlorpyrifos. Presented at the Society for Risk Analysis Annual Meeting, Boston, MA, December 7-10, 2008. |
R831709 (Final) R832733 (2009) |
|
| Presentation | Griffith W. Organophosphate pesticide gene-environment interactions: lessons learned and future challenges. Presented at the 40th Annual Meeting of the Environmental Mutagen Society, St. Louis, MO, October 26, 2009. |
R831709 (2007) R831709 (Final) |
|
| Presentation | Guerrette Z, Moreira EG, Griffith WC, Coronado GD, Vigoren EM, Yu X, Thompson B, Faustman EM. Cytochrome P450 3A5 genotype is correlated with acetylcholinesterase inhibition levels after exposure to organophosphate pesticides. Poster presented at the Society of Toxicology 50th Annual Meeting & ToxExpo, Washington, DC, March 6-10, 2011. |
R831709 (Final) R834514 (2011) R834514 (2012) |
not available |
| Presentation | Hong S, Kim E, Griffith WC, Yu X, Robinson JF, Faustman EM. Characterization of repeated maternal chlorypyrifos exposure induced acetylcholinesterase inhibition in maternal and fetal brain of C57BL/6J mice. Presented at the Teratology Society Annual Meeting, Tucson, AZ, June 24-29, 2006. |
R831709 (Final) |
not available |
| Presentation | Karr CJ, Beaudet N, Kieu Q, Nguyen Q, Keifer M. Building global children's environmental health capacity: partnership in Vietnam. Poster presented at the CDC National Environmental Public Health Conference, Atlanta, GA, October 26-28, 2009. |
R831709 (Final) R834514 (2012) |
not available |
| Presentation | Kim H, Yu X, Hong S, Park J, Faustman EM. Differential effect of chloropyrifos on epigenetic markers in proliferating and differentiating human neural stem cell. Poster presented at the Society of Toxicology 50th Annual Meeting & ToxExpo, Washington, DC, March 6-10, 2011. |
R831709 (Final) R834514 (2011) R834514 (2012) |
not available |
| Presentation | Marsillach J, Richter RJ, Cole TB, Kim JH, Stevens R, MacCoss M, Tomazela D, Hsieh E, Suzuki S, Schopfer LM, Lockridge O, Furlong CE. Human biomarkers for tricresyl phosphate exposure. Poster presented at the Society of Toxicology 50th Annual Meeting & ToxExpo, Washington, DC, March 6-10, 2011. |
R831709 (Final) R834514 (2011) R834514 (2012) |
not available |
| Presentation | Moreira EG, Robinson JF, Hong S, Griffith WC, Yu X, Faustman EM. Toxicogenomic profiling in the fetal brain after gestational exposure to chlorpyrifos. Presented at the Teratology Society Annual Meeting, Rio Grande, Puerto Rico, June 27-July 1, 2009. |
R831709 (Final) |
not available |
| Presentation | Moreira EG, Coronado GC, Thompson B, Vigoren EM, Griffith WC, Faustman EM. Urinary concentrations of dialkyl organophosphate metabolites in farmworkers and non-farmworkers and their children in a longitudinal cohort study. Presented at the Society of Toxicology Annual Meeting, Baltimore, MD, March 15-19, 2009. |
R831709 (Final) R832733 (2009) |
|
| Presentation | Ramaprasad J, Tsai T, Elgethun K, Herbert V, et al. Increased pesticide exposure among agricultural communities in Washington caused by volatilization from sprayed fields. Presented at the Society for Risk Analysis 2004 Annual Meeting, Palm Springs, CA, December 5-8, 2004. |
R831709 (Final) R831709C004 (2005) |
not available |
| Presentation | Robinson JF, Hong S, Griffith WC, Yu XZ, Sullivan R, Kim N, Zarbl H, Faustman EM. Differential impact of cadmium on gene expression during neuralation in the C57BL/6 and SWV. Presented at the Teratology Society Annual Meeting, Tucson, AZ, June 24-29, 2006. |
R831709 (Final) |
not available |
| Presentation | Robinson JF, Yu X, Gribble EJ, Hong S, Kim E, Sidhu J, Faustman EM. Examination of arsenic-induced alterations in cell cycle progression and global gene expression in P53 transgenic mouse emryonic fibroblasts. Presented at the Society of Toxicology Annual Meeting, San Diego, CA, March 5-9, 2006. |
R831709 (Final) |
not available |
| Presentation | Robinson JF, Yu XZ, Hong S, Kim E, Griffith WC, Faustman EM. Examination of metal induced toxicogenomic response during neurulation in resistant and sensitive mouse strains. Presented at the Society of Toxicology Annual Meeting, Charlotte, NC, March 25-29, 2007. |
R831709 (Final) |
not available |
| Presentation | Robinson J, Yu X, Sidhu J, Hong S, Kim E, Faustman EM. Examination of metal-induced cell cycle alterations and apoptosis in C57BL/6 and SWV mouse embryonic fibroblasts. Presented at the Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. |
R831709 (Final) R831709C001 (2005) |
not available |
| Presentation | Sathyanarayana S, Zhou C, Rudra C, Gould T, Larson T, Karr C. Prenatal ambient air pollution exposure and small for gestational age birth in the Puget Sound air basin. Poster presented at the Pediatric Academic Societies' Annual Meeting, Baltimore, MD, May 2-5, 2009. |
R831709 (Final) R834514 (2012) |
not available |
| Presentation | Tsai M, Yost MG, Felsot AS, Galvin K, Fenske RA, Larson TV. Pesticide spray drift monitoring of orchard airblast application: New approaches. Presented at the Joint ISEE/ISEA Conference on Environmental Epidemiology and Exposure (18th ISEE Conference and 16th ISEA Conference), Paris, France, September 2-6, 2006. |
R831709 (Final) R831709C004 (2007) |
not available |
| Presentation | Vigoren EM, Griffith WC, Krogstad F, Faustman EM. Integrative tools for improving our evaluation of accountability:lessons for pesticide biomarker studies. Presented at the Society for Risk Analysis Annual Meeting, Boston, MA, December 7-10, 2008. |
R831709 (Final) R832733 (2009) |
|
| Presentation | Vigoren EM, Griffith WC, Coronado GD, Thompson B, Faustman EM. Longitudinal study of exposure to organophosphate pesticides comparing farmworker and nonfarmworker population. Poster presented at the Society for Risk Analysis Annual Meeting, Baltimore, MD, December 6-9, 2009. |
R831709 (Final) R834514 (2012) |
not available |
| Presentation | Vigoren E, Griffith W. Methods for assessing the effect of a randomized community educational intervention on the take-home pathway of organophosphate pesticide exposure. Presented at the Society for Risk Analysis Annual Meeting, Baltimore, MD, December 3-6, 2006. |
R831709 (2005) R831709 (Final) |
not available |
| Presentation | Vredevoogd M, Yu X. Challenges in Incorporating Genomic Information into Risk Assessment:Development of a Systems Biology Framework. Presented at the Society for Risk Analysis Annual Meeting, Palm Springs, CA. December 5-8, 2004. |
R831709 (2005) R831709 (Final) |
not available |
| Presentation | Vredevoogd M, Yu X, Hong S, Faustman EM. Critical molecular pathways of neurogenesis in chlorpyriphos response. Presented at the Society of Toxicology Annual Meeting, Seattle, WA, March, 2008. |
R831709 (Final) R832733 (2009) |
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| Presentation | Yost M, Tsai MY, Fenske R. Air Blast Applications: Pesticide drift deposition modeling. Presented at at the Health & Safety in Western Agriculture Conference: Research to Practice. Agrochemical/Respiratory Protection Session-R2P, Pacific Grove, CA, September 20-22, 2006. |
R831709 (Final) R831709C004 (2007) |
not available |
| Presentation | Yu X. A system based approach to identify potential signalling pathways during gonad development from microarray data. Presented at the Teratology Society Annual Meeting, Tucson, AZ, June 24-29, 2006. |
R831709 (Final) |
not available |
| Presentation | Gholke JM, Griffith WC, Faustman EM. A computational model for the evaluation of interspecies variability during ethanol induced inhibition of neocortical neurogenesis. Presented at the Teratology Society Annual Meeting, Philadelphia, PA, 2003. |
R831709 (Final) |
not available |
| Presentation | Faustman EM, Yu XZ, Hong S, Sidhu JS. An improved primary sertoli cell-gonocyte co-culture system from neonate rat:in vitro model for the assessment of male reproductive toxicity. Presented at the Society of Toxicology Annual Meeting, Salt Lake City, UT, 2003. |
R831709 (Final) |
not available |
| Presentation | Alaniz M, Coronado GD, Thompson B. Attitudes and beliefs about pesticide exposure among warehouse workers in Washington State. Presented at the Annual Society for the Advancement of Chicanos and native Americans in Science Meeting, Albuquerque, NM, 2003. |
R831709 (Final) |
not available |
| Presentation | Martinez A, Coronado GD, Thompson B. Attitudes and beliefs about pesticides among Hispanic and non-Hispanic white farmworkers in Washington State. Presented at the American Public Health Association, San Francisco CA, 2003. |
R831709 (Final) |
not available |
| Presentation | Griffith WC, Gohlke JM, Lewandowski T, Mendoza MC, Ponce R, Faustman EM. Building BBDR models for cell signaling pathways using transgenic animal models. Presented at the Society of Toxicology, Baltimore, MD, 2003. |
R831709 (Final) |
not available |
| Presentation | Faustman EM, Judd NL, Ponce R, Griffith WC. Considerations of cultural and lifestyle factors in defining susceptible populations for environmental disease. Presented at the 5th Congress of Toxicology in Developing Countries, Guilin, China, 2003. |
R831709 (Final) |
not available |
| Presentation | Garry Mr, Sidhu JS, Kavanugh TJ, Faustman EM. Differential modulation of stress and ubiquitination signaling Pathways by cadmium, H2O2, and serum withdrawal in cultured mouse fibroblasts. Presented at the Society of Toxicology Annual Meeting, Salt Lake City, UT, 2003. |
R831709 (Final) |
not available |
| Presentation | Yu XZ, Faustman EM, Hong S, Sidhu JS. Effects of methylmercury and cadmium on stress signalling and ubiquitination pathways in a primary sertoli cell-gonocyte co-culture system. Presented at the Society of Toxicology Annual Meeting, Salt Lake City, UT, 2003. |
R831709 (Final) |
not available |
| Presentation | Gribble EJ, Mendoza A, Hong S, Sidhu JS, Faustman EM. Evaluation of cell cycle kinetics in p53 mouse embryonal fibroblasts:effects of methylmercury. Presented at the Society of Toxicology Annual Meeting, Salt Lake City, UT, 2003. |
R831709 (Final) |
not available |
| Presentation | Gohlke JM, Griffith WC, Faustman EM. Evaluation of interspecies variability during neocortical neurogenesis using biologically based computational models. Presented at the Society of Toxicology Annual Meeting, Salt Lake City, UT, 2003. |
R831709 (Final) |
not available |
| Presentation | Godina R, Coronado GD, Thompson B. Evaluation of the home health party approach in the take-home pesticide exposure pathway. Presented at the American Public Health Association Annual Meeting, San Francisco, CA, 2003. |
R831709 (Final) |
not available |
| Presentation | Tin CC, Sidhu JS, Hong S, Kim E, Faustman EM. Examination of the role of p53-associated cell cycle gene expression induced by methylmercury in mouse embryonal fibroblasts.Presented at the Society of Toxicology Annual Meeting, Salt Lake City, UT, 2003. |
R831709 (Final) |
not available |
| Presentation | Holland N, Furlong CE, Birch K, Richter RJ, Bastaki M, Weltzien E, Bradman A, Jampsa R, Eskenazi B. Functional genomics and pesticide exposure in children and pregnant women. Presented at the Environmental Mutagen Society, Orlando, FL, 2003. |
R831709 (Final) |
not available |
| Presentation | Cole TB, Jarvik GP, Richter RJ, Jampsa R, Carlson CS, Rieder MJ, Nickerson DA, Shih DM, Lusis AJ, Costa LG, Furlong CE. Functional genomics of the paraozonase (PON1) polymorphisms. Presented at the Annual Meeting of the American Society of Biochemistry and Molecular Biology (ASBMB), San Diego, CA, 2003. |
R831709 (Final) |
not available |
| Presentation | Sidhu JS, Hong S, Erickson A, Baker A, Robinson J, Vliet P, Faustman EM. Methylmercury induces differential ubiquitin-conjugated protein levels in p53 variant mouse embryonal fibroblasts. Presented at the Society of Toxicology, Salt Lake City, UT, 2003. |
R831709 (Final) |
not available |
| Presentation | Furlong CE, Rieder MJ, Carlson C, Nickerson D, Jampsa R, Costa LG, Jarvik GP. New polymorphisms in the human paraoxonase (PON1) gene. Presented at the Society of Toxicology Annual Meeting, Salt Lake City, UT, 2003. |
R831709 (Final) |
not available |
| Presentation | Godina R, Coronado GD, Thompson B. Provision and use of personal protective equipment among farmworkers in Washington State. Presented at the Annual Society for the Advancement of Chicanos and Native Americans in Science Meeting, Albuquerque, NM, 2003. |
R831709 (Final) |
not available |
| Presentation | Hong S, Sidhu KS, Kim E, Faustman EM. Refinement of a high-throughput 2D-Page technique for the evaluation of ubiquitin-conjugated protein status induced by developmental toxicants. Presented at the Society of Toxicology, Salt Lake City, UT, 2003. |
R831709 (Final) |
not available |
| Presentation | Strong L, Thompson B, Coronado GD, Griffith WC, Islas I. Reported health symptoms and pesticide exposure among farmworkers in Central Washington. Presented at the American Public Health Association, San Francisco CA, 2003. |
R831709 (Final) |
not available |
| Presentation | Yu XZ, Sidhu JS, Hong S, Faustman EM. Cadmium-induced apoptosis, activation of MAPK signaling pathways and accumulation of ubiquitinated-protein-conjugates in primary rat neonatal sertoli-gonocyte co-cultures. Presented at the Society of Toxicology Annual Meeting, Baltimore, MD, 2004. |
R831709 (Final) |
not available |
| Presentation | Faustman EM. Center for child environmental health risks research. Presented at the International Society for Environmental Epidemiology Annual Conference, New York City, NY, 2004. |
R831709 (Final) |
not available |
| Presentation | Drew CH, Faustman EM. Challenges and opportunities in utilizing systems biology approaches for informing developmental toxicology. Presented at the Society of Toxicology, Baltimore, MD, 2004. |
R831709 (Final) |
not available |
| Presentation | Wong E, Gohlke JM, Griffith WC, Faustman EM. Children's health benefits from reductions in criteria air pollution concentrations. Presented at the Society of Toxicology Annual Meeting, Baltimore, MD, 2004. |
R831709 (Final) |
not available |
| Presentation | DeFrank MN, Griffith WC, Gohke JM, Faustman EM. Computational model for radiation-induced cell death at low doses in the developing neocortex. Presented at the Society of Toxicology, Baltimore, MD, 2004. |
R831709 (Final) |
not available |
| Presentation | Gholke JM, Griffith WC, Faustman EM. Contribution of experimental and inter and intraspecies variability in a computational model for ethanol-induced perturbations of neocortical development. Presented at the Society of Toxicology, Baltimore, MD, 2004. |
R831709 (Final) |
not available |
| Presentation | Sidhu JS, Hong S, Yu XZ, Kim E, Erickson A, Robinson JF, Kim S, Vredevoogd, Faustman EM. Defining P53-dependent and independent mechanisms of cadmium-induced cytotoxicity, stress signaling, apoptosis and ubiquitin proteasome pathway processing. Presented at the Society of Toxicology Annual Meeting, Baltimore, MD, 2004. |
R831709 (Final) |
not available |
| Presentation | Furlong CE. Functional genomics of PON1. Presented at the 1st International Conference Paraoxonases Basic and Clinical Directions of Current Research, Ann Arbor, MI, 2004. |
R831709 (Final) |
not available |
| Presentation | Furlong CE, Cole TB, Pettan-Brewer C, Geiss G, Richter RJ, Shih DM, Tward A, Lusis AJ, Costa LG. Genetic and temporal determinants of pesticide sensitivity in children:role of paraoxonase (PON1). Presented at the 21st International Neurotoxicology Conference, Honolulu, HI, 2004. |
R831709 (Final) |
not available |
| Presentation | Bradley AB, Cullen AC, Burke E, Faustman EM. Impact and policy implications of genetic information in regulation:a case study of organophosphate pesticides. Presented at the Society for Risk Analysis Annual Meeting. December, Palm Springs, CA, 2004. |
R831709 (Final) |
not available |
| Presentation | Griffith WC, Curl CL, Faustman EM, Li CA, Fenske RA. Large within child variability for OP pesticide urinary biomarkers limits our ability to identify high exposure farm worker children. Presented at the Society of Toxicology Annual Meeting, Baltimore, MD, 2004. |
R831709 (Final) |
not available |
| Presentation | Gribble EJ, Mendoza A, Hong S, Sidhu JS, Faustman EM. Mechanism of cell cycle arrest in methyl mercury p53 mouse embryonal fibroblasts:Role of checkpoint pathways in developmental toxicology. Presented at the Teratology Society Annual Meeting, Vancouver, Canada, 2004. |
R831709 (Final) |
not available |
| Presentation | Cole TB, Pettan-Brewer C, Richter RJ, Shih DM, Tward A, Lusis AJ, Costa LG, Furlong CE. Paraoxonase abundance and Q192R genotype are important determinants of organophosphate toxicity during development. Presented at the Society of Toxicology, Baltimore, MD, 2004. |
R831709 (Final) |
not available |
| Presentation | Judd NL, Griffith WC, Schumacher KM, Faustman EM. Quantitative considerations for developing and improving kinetic and dynamic models of chlorpyrifos developmental neurotoxicity. Presented at the 10th International Congress of Toxicology, Tampere, Finland, 2004. |
R831709 (Final) |
not available |
| Presentation | Furlong Ce, Cole TB, Li WF, Carlson C, Nickerson D, Jarvik GP, Lusis AJ, Tward A, Shih DM, Costa LG. Significance of genetic variability in the human PON1 gene explored in a mouse model. Presented at the 17th International Mouse Genome Conference, Seattle, WA, 2004. |
R831709 (Final) |
not available |
| Presentation | Gribble EJ, Hong S, Yu XZ, Faustman EM. Association of cell cycle regulatory proteins with cell cycle exit and differentiation in mouse embryonic midbrain neuronal precursor cells. Presented at the 22nd International Neurotoxicology Conference, Research Triangle Park, NC, 2005. |
R831709 (Final) |
not available |
| Presentation | Strong L, Thompson B, Koepsell T, Coronado GD. Beliefs, demographics, and pesticide safety practices in farmworkers. Presented at the Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. |
R831709 (Final) |
not available |
| Presentation | Guizzetti M, Pathak S, Giordano G, Costa LG. Effect of organophosphorus insecticides and their metabolites on DNA synthesis in astroglial cells. Presented at the Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. |
R831709 (Final) |
not available |
| Presentation | Robinson JF, Yu XZ, Sidhu JS, Hong S, Kim E, Faustman EM. Examination of metal-induced cell cycle alterations and apoptosis in C57BL/6 and SWV mouse embryonic fibroblasts. Presented at the Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. |
R831709 (Final) |
not available |
| Presentation | Robinson SH, Needham L, Faustman EM, Zenick H, Sheldon L. Integration of biomonitoring data into the risk assessment process. Presented at the Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. |
R831709 (Final) |
not available |
| Presentation | Yu XZ, Sidhu JS, Robinson J, Hong S, Faustman EM. Integrative analysis of genome-wide gene expression and pathway mapping in mouse embryonic fibroblast (MEF) exposed to cadmium, arsenic, and methylmercury:induction of oxidative stress, disruption of ubiquitin-proteasome system and cell cycle regulation. Presented at the Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. |
R831709 (Final) |
not available |
| Presentation | Gohlke JM, Bartell SM, Wong EY, Lewandowski TA, Griffith WC, Faustman EM. Mechanisms based approaches to evaluate the impacts of life stage specific exposures during neurodevelopment. Presented at the Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. |
R831709 (Final) |
not available |
| Presentation | Faustman EM, Cullen AC, Griffith WC, Kramer CB, Bradley AM. New technology and science into risk assessment:Why isn’t it making a difference?. Presented at the Society for Risk Analysis Annual Meeting, Orlando, FL, 2005. |
R831709 (Final) |
not available |
| Presentation | Pettan-Brewer C, Cole TB, Fisher J, Walter B, Forbes A, Yee S, Costa LG, Furlong CE. PON1 modulates OP toxicity during development. Presented at the Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. |
R831709 (Final) |
not available |
| Presentation | Furlong CE, Cole TB, Pettan-Brewer C, Shih DM, Tward A, Lusis AJ, Timchalk C, Richter RJ, Costa LG. Paraoxonase (PON1) status affects the metabolism of drugs and insecticides. Presented at the 13th North American International Society for the Study of Xenobiotics (ISSX) Joint Meeting/20th Japanese Society for the Study of Xenobiotics (JSSX) Meeting, Maui, HI, 2005. |
R831709 (Final) |
not available |
| Presentation | Griffith WC, DeFrank MN, Gohlke JM, Gribble EJ, Faustman EM. Systems biology models as a tool to integrate diverse studies of the developing neocortex after exposure to low dose radiation. Presented at the 42nd Congress of the European Societies of Toxicology, Krakow, Poland, 2005. |
R831709 (Final) |
not available |
| Presentation | Cole TB, Walter BJ, Shih DM, Tward A, Lusis AJ, Costa LG, Furlong CE. Toxicity of chlorpyrifos and chlorpyrifos oxon in a transgenic mouse model of the human paraoxonase (PON1) Q192R polymorphisms. Presented at the Society of Toxicology Annual Meeting, New Orleans, LA, 2005. |
R831709 (Final) |
not available |
| Presentation | Gribble JE, Yu X, Hong S, Faustman EM. A Role for P53 in mouse midbrain neural precursor cell (NPC) cell cycle arrest and premature neuronal differentiation following methylmercury exposure. Presented at the Society of Toxicology Annual Meeting, San Diego, CA, 2006. |
R831709 (Final) |
not available |
| Presentation | Yost MG, Tsai M, Fenske RA. Air blast applications:pesticide drift deposition modeling. Presented at the Health and Safety in Western Agriculture Conference, Pacific Grove, CA, 2006. |
R831709 (Final) |
not available |
| Presentation | Yu XZ, Griffith WC, Hanspers K, Robinson JF, Faustman EM. Functional interpretation of dose and time-dependent microarray data:quantitative integration of go ontology Analysis for toxicology and risk assessment. Presented at the Society of Toxicology Annual Meeting, San Diego, CA, March 5-9, 2006. |
R831709 (Final) |
not available |
| Presentation | Tsai M, Yost M, Felsot AS, Galvin K, Fenske RA, Larson TV. Pesticide spray drift monitoring of orchard airblast application:new approaches. Presented at the Joint ISEE/ISEA Conference on Environmental Epidemiology and Exposure, Paris, France, 2006. |
R831709 (Final) |
not available |
| Presentation | Faustma EM, Yu XZ, Griffith WC, Hanspers K, Ong H, Vredevoogd M, Dillman JF. Quantitative interpretation of dose and time dependent microarray data using a gene ontology systems biology approach. Presented at the Congress of the European Societies of Toxicology (EuroTOX) Annual Meeting, Dubrovnik, Croatia, 2006. |
R831709 (Final) |
not available |
| Presentation | Giordano G, Afsharineiad Z, Kavanaugh TJ, Costa LG. Reactive oxygen species mediate the neurotoxicity induced by organophosphorus insecticides in mouse cerebellar granule cells. Presented at the Society of Toxicology Annual Meeting, San Diego, CA, 2006. |
R831709 (Final) |
not available |
| Presentation | Yu X, Hong S, Kim E, Faustman EM. Characterization of male reproductive toxicants in an in vitro 3D sertoli cell/gonocyte co-culture. Presented at the Society of Toxicology Annual Meeting, Charlotte, NC, 2007. |
R831709 (Final) |
not available |
| Presentation | Gholke JM, Griffith WC, Faustman EM. Computational modeling of ethanol induced neurodevelopmental toxicity across species:implications for risk assessment. Presented at the Teratology Annual Meeting, Pittsburgh, PA, 2007. |
R831709 (Final) |
not available |
| Presentation | Faustman EM. Environmental risk to children in developing countries. Presented at the 5th Annual Western Regional International Health Conference, Seattle, WA, 2007. |
R831709 (Final) |
not available |
| Presentation | Vigoren E, Griffith WC, Krogstad FTO, Coronado GC, Thompson B, Faustman EM. Formal uncertainty analysis in the interpretation organophosphate pesticide metabolite concentrations. Presented at the Society for Risk Analysis Annual Meeting, Nashville, TN, 2007. |
R831709 (Final) |
not available |
| Presentation | Faustman EM, Yu XZ, Hong S. Improving in vitro models for assessing male reproductive toxicity:incorporating genomic considerations. Presented at the International Congress of Toxicology Meeting, Montreal, Canada, 2007. |
R831709 (Final) |
not available |
| Presentation | Vredevoogd M, Yu XZ, Griffith WC, Faustman EM. Quantification of genomic data:value-added assessment and applicability to toxicologically significant endpoints. Presented at the Society of Toxicology Annual Meeting, Charlotte, NC, 2007. |
R831709 (Final) |
not available |
| Presentation | Faustman EM, Yu X, Griffith WC. The future of genomics in dose response modeling:useful lessons from systems based approaches. Presented at the Society of Toxicology Annual Meeting, Charlotte, NC, 2007. |
R831709 (Final) |
not available |
| Presentation | Faustman EM. The interface of chemistry and biology in the omics era:environmental and health and drug discovery. Presented at the 6th Princess Chulabhorn International Science Congress, Bangkok, Thailand, 2007. |
R831709 (Final) |
not available |
| Presentation | Faustman EM, Griffith WC. Toxicodynamic considerations in PBPK models. Presented at the Society for Risk Analysis Annual Meeting, San Antonio, TX, 2007. |
R831709 (Final) |
not available |
| Presentation | Griffith WC, DeFrank MN, Gohlke JM, Faustman EM. Value of information approach for development of models of the developing neocortex after exposure to low dose radiation from internally deposited radionuclides. Society of Toxicology Annual Meeting, Charlotte, NC, 2007. |
R831709 (Final) |
not available |
| Presentation | Stevens R, Soelberg Sd, Kauffman P, Furlong CE. A portable SPR biosensor for detection of small molecules. Presented at the Association of Official Analytical Chemists Annual Meeting, Dallas, TX, 2008. |
R831709 (Final) |
not available |
| Presentation | Guerette Z, Yu XZ, Hong S, Kim E, Faustman EM. Arsenic induces different cell signaling pathways leading to apoptosis and cell cycle arrest in p53 +/+ and p53-/-cells. Presented at the Society of Toxicology Annual Meeting, Seattle, WA, 2008. |
R831709 (Final) |
not available |
| Presentation | Guerette Z, Yu XZ, Hong S, Kim E, Faustman EM. Arsenic induces different cell signaling pathways leading to apoptosis and cell cycle arrest in p53 +/+ and p53-/-cells. Presented at the Society of Toxicology Annual Meeting, Seattle, WA, 2008. |
R831709 (Final) |
not available |
| Presentation | Hofmann J, Stevens R, MacCoss M, Goodlett D, Sherl AC, Keifer MC, Checkoway H, Kim JH, Richter RJ, Suzuki SM, Farin FM, De Roos AJ, Furlong CE. Biomarkers of sensitivity and exposure in Washington State pesticide handlers. Presented at the 3rd International Conference on Paraoxonases, Los Angeles, CA, 2008. |
R831709 (Final) |
not available |
| Presentation | Robinson JF, Yu XZ, Hong S, Faustman EM. Comparative gene expression analysis in c57 mouse embryos undergoing neurulation exposed to cadmium and methylmercury. Presented at the Society of Toxicology Annual Meeting, Seattle, WA, 2008. |
R831709 (Final) |
not available |
| Presentation | Furlong CE, Suzuki S, Stevens R, Cole TB, Richter RJ. Engineering human paraoxonase 1 (PON1) in an E coli expression system for therapeutic applications. Presented at the 3rd International Conference on Paraoxonases, Los Angeles, CA, 2008. |
R831709 (Final) |
not available |
| Presentation | Robinson JF, Yu X, Hong S, Faustman EM. Examination of dose and time dependent arsenic cadmium-induced gene expression response in C57BL/6 mouse embryos undergoing neurulation. Presented at the Teratology Society Annual Meeting, Monterey, CA, 2008. |
R831709 (Final) |
not available |
| Presentation | Yu XZ, Hong S, Faustman EM. Germ-line stem cells-gonocytes as an in vitro model for male developmental toxicity:comparison from cytotoxicity to genomic responses to phthalates. Presented at the Society of Toxicology Annual Meeting, Seattle, WA, 2008. |
R831709 (Final) |
not available |
| Presentation | Cole TB, Jansen K, Li WF, Furlong CE, Costa LG. Paraoxonase (PON1) modulates the toxicity of OP mixtures. Presented at the 3rd International Conference on Paraoxonases, Los Angeles, CA, 2008. |
R831709 (Final) |
not available |
| Presentation | Richter RJ, Costa LG, Jarvik GP, Zabetian CP, Checkoway H, Samii A, Roberts JW, Yearout D, Furlong CE. Paraoxonase 1 (PON1) status as a risk factor for disease exposure. Presented at the 3rd International Conference on Paraoxonases, Los Angeles, CA, 2008. |
R831709 (Final) |
not available |
| Presentation | Suzuki S, Stevens R, Richter RJ, Cole TB, Park S, Otto TC, Cerasoli DM, Lenz DE, Furlong CE. Recombinant human PON1 engineered in an E coli expression system. Presented at the 3rd International Conference on Paraoxonases, Los Angeles, CA, 2008. |
R831709 (Final) |
not available |
| Presentation | Hofmann J, De Roos A, Furlong CE, Farin F, Fenske RA, Checkoway H, Keifer M. Serum cholinesterase inhibition in relation to paraoxonase status among organophosphate-exposed agricultural pesticide handlers. Presented at the 20th International Conference on Epidemiology in Occupational Health, San Jose, Costa Rica, 2008. |
R831709 (Final) |
not available |
| Presentation | Hofmann J, De Roos A, Furlong CE, Farin F, Fenske RA, Checkoway H, Keifer M. Serum cholinesterase inhibition in relation to paraoxonase status among organophosphate-exposed agricultural pesticide handlers. Presented at the 20th International Conference on Epidemiology in Occupational Health, San Jose, Costa Rica, 2008. |
R831709 (Final) |
not available |
| Presentation | Tsai M, Yost MG, Larson TV. The Washington orchard spray drift study:lidar imaging of pesticide spray drift from an orchard airblast sprayer. Presented at the Air and Waste Management Association's 101st Annual Conference and Exhibition, Portland, OR, 2008. |
R831709 (Final) |
not available |
| Presentation | Faustman EM. Translations of toxicology into public health practices:successes and challenges. Presented at the Society of Toxicology Annual Meeting, Seattle, WA, 2008. |
R831709 (Final) |
not available |
| Presentation | Faustman EM, Yu X, Griffith WC, Robinson JF. Useful lessons for toxicogenomics using systems based approached for dose and temporal response modeling. Presented at the Society for Risk Analysis Annual Meeting, Boston, MA, 2008. |
R831709 (Final) |
not available |
| Presentation | Griffith WC, Schumacher KM, Ramaprasad J, Faustman EM. Using simple kinetic models to integrate experimental datasets:lessons learned with chlorpyrifos. Presented at the Society for Risk Analysis Annual Meeting, Boston, MA, 2008. |
R831709 (Final) |
not available |
| Presentation | Karr C. Asthma and environmental factors:putting the evidence into practice. Presented at the 4th Annual Alaska Asthma and Allergy Foundation Conference, Alyeska, AK, 2009. |
R831709 (Final) |
not available |
| Presentation | Karr C, Demer PA, Lencar C, Koehoorn M, Tamburic L, Brauer M. Influence of ambient air pollutant sources on clinical encounters for infant bronchiolitis. Pediatric Academic Societies' Annual Meeting, Baltimore, MD, 2009. |
R831709 (Final) |
not available |
| Presentation | Griffith WC, Vigoren EM, Coroando GD, Thompson B, Faustman EM. Inhibition of acetylcholinesterase in a farmwork population exposed to organophosphate pesticides. Presented at the Society for Risk Analysis Annual Meeting, Baltimore, MD, 2009. |
R831709 (Final) |
not available |
| Presentation | Costa LG, Pizzurro D, Dao K, Guizzetti M, Giordano G. Manganese impairs the ability of astrocytes to promote neurite outgrowth in rat hippocampal neurons. Presented at the Society of Toxicology Annual Meeting, Baltimore, MD, 2009. |
R831709 (Final) |
not available |
| Presentation | Faustman EM. New methodological approaches for understanding and characterizing vulnerability in children's response to organophosphate exposure. Presented at the Pediatric Academic Societies Annual Meeting, Baltimore, MD, 2009. |
R831709 (Final) |
not available |
| Presentation | Griffith WC, Coronado GC, Vigoren E, Thompson B, Faustman EM. Predictors of organophosphate pesticide residues in home environment dust of farmworkers. Presented at the Society of Toxicology Annual Meeting, Baltimore, MD, 2009. |
R831709 (Final) |
not available |
| Presentation | Faustman EM. What can Darwin tell us about pathways based risk assessment?. Presented at the Society for Risk Analysis Annual Meeting, Baltimore, MD, 2009. |
R831709 (Final) |
not available |
| Presentation | Robinson JF, Xu Y, Hong S, Griffith WC, Faustman EM. A systems-biology approach for characterizing and assessing the interaction of developmental disease candidate genes and environmental exposure for risk assessment. Presented at the Teratology Society Annual Meeting, Louisville, KY, 2010. |
R831709 (Final) |
not available |
| Presentation | Marsillach J, Richter RJ, Kim JH, Stevens RC, MacCoss M, Tomazela D, Suzuki S, Schopfer LM, Lockrdige O, Furlong CE. Biomarkers of organophosphorus (OP) exposures in humans. Presented at the 26th International Neurotoxicology Conference, Portland, OR, 2010. |
R831709 (Final) |
not available |
| Presentation | Furlong CE, Cole TB, Jansen KL, Richter RJ, Bammler TK, Beyer RP, Farin F, Costa LG. Genetic variability factors in human susceptibility to Organophosphorus compounds. Presented at the 12th International Congress of Toxicology (ICT) Meeting, Barcelona, Spain, 2010. |
R831709 (Final) |
not available |
| Presentation | Moreira EG, Griffith WC, Coronado GD, Thompson B, Vigoren EM, Richter RJ, Furlong CE, Faustman EM. PON1 status and blood cholinesterases in a farmworker population exposed to organophosphate pesticides. Presented at the 12th International Congress of Toxicology (ICT) Meeting, Barcelona, Spain, 2010. |
R831709 (Final) |
not available |
| Presentation | Furlong CE, Richter RJ, Jarvik GP, Checkoway H, Samii A, Costa LG, Griffith A, Roberts JW, Yearout D, Zabetian CP, Ticozzi N, LeClerc AL, Keagle P, Glass JD, Wills AM, Van Blitterswijk M, Bosco DA, Rodriguez-Levva I, Gellera C, Ratti A, Taroni F, McKenna-Yasek DM, Sapp PC, Silani V, Brown RH. Paraoxonase 2 (PON2) in the central nervous system:a neuroprotective role? . Presented at the 4th International Conference on Paraoxonases, La Pineda, Spain, 2010. |
R831709 (Final) |
not available |
| Presentation | Ticozzi N, LeClerc AL, Keagle P, Glass JD, Willis AM, Van Blitterswijk M, Bosco DA, Rodriguez-Levva, Gellarca C, Ratti A, Taroni F, McKenna-Yasek DM, Sapp PC, Silani V, Furlong CE, Brown RH, Landers JE. Paraoxonase gene mutations in amyotrophic lateral sclerosis. Presented at the Amytrophic Lateral Sclerosis (ALS)/Motor Neurone Disease (MND) International Meeting, Orlando, FL, 2010. |
R831709 (Final) |
not available |
| Presentation | Furlong CE, Marsillach J, Richter RJ, Kim JH, Stevens RC, Tomazela D, Suzuki S, Cole TB, Baker PE, Schopfer LM, Lockridge O, MacCoss M. Biomarkers of organophosphate exposure. Presented at the Gordon-Research Conference, Ventura, CA, 2011. |
R831709 (Final) |
not available |
| Presentation | Suzuki S, Stevens RC, Richter RJ, Cole TB, Furlong CE. Expression, purification and characterization of human PON1 mutants in an E. coli system. Presented at the Gordon-Research Conference, Ventura, CA, 2011. |
R831709 (Final) |
not available |
| Presentation | Marsillach J, Richter RJ, Cole TB, Kim JD, Stevens RC, MacCoss M, Tomazela D, Hsieh E, Suzuki S, Schopfer LM, Lockridge O, Furlong CE. Isolation and characterization of human biomarkers of OP exposure. Presented at the Gordon-Research Conference, Ventura, CA, 2011. |
R831709 (Final) |
not available |
| Presentation | Costa LG, Giordano G, Cole TB, Furlong CE. Paraoxonase 2 (PON2) in the central nervous system:a neuroprotective role?. Presented at the Society of Toxicology 50th Anniversary Meeting, Washington, DC, 2011. |
R831709 (Final) |
not available |
| Presentation | Karr C, White J. Implementing child product chemical safety policy. Presented at the CDC National Environmental Public Health Conference, Atlanta, GA, 200. |
R831709 (Final) |
not available |
| Presentation | Faustman EM. Pesticide exposure in children:evidence for a take home pathway. Presented at the Teratology Annual Meeting, Monterey, CA, 2008.Faustman EM. Risk assessment, risk management, and indigenous people:legal, scientifc, social and cultural contexts. Presented at the 2nd Annual World Congress on Risk, Guadalajara, Mexico, 2008. |
R831709 (Final) |
not available |
| Proceedings | Costa L. PON1 and organophosphate toxicity. In: Proccedings of the 2nd International Conference on Paraoxonases, Hajduszoboszio, Hungary, September 7-10, 2006. |
R831709 (Final) R831709C002 (2007) |
not available |
| Proceedings | Furlong C. The functional consequences of polymorphisms in the human PON1 gene. In: Proccedings of the 2nd International Conference on Paraoxonases, Hajduszoboszio, Hungary, September 7-10, 2006. |
R831709 (Final) R831709C002 (2007) |
not available |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.