Grantee Research Project Results
Research Centers
Environmental Determinants of Airway Disease in Children
3D ARRAY TECHNOLOGY LLC
This Center is looking into possible causes of asthma and other respiratory diseases, which are the most common chronic childhood illnesses. Symptoms can include coughing and difficulty breathing, dramatically affecting a child’s quality of life. Environmental exposures may impair the lung’s ability to respond to irritants and increase a child’s risk of developing respiratory disease. Researchers are focusing on ozone and bacterial endotoxin, which are common environmental exposures and can be inhaled. Ozone is an air pollutant and a component of smog while endotoxins are part of the cell wall of some bacteria, released into the air when the bacteria die. Since both of these agents can affect immune system response, researchers believe that such exposures could alter the response of the innate and developing immune system, leading to lung inflammation and impaired lung function, making a child more susceptible to getting asthma or other lung diseases.
Center Publications:
Views: | All publications | Selected publication types | Journal articles | Publications submitted after final report |
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Identifier | Abstract | Principal Investigator |
Annual/ Final Reports |
Pubs Count | Institution | Grant Representative |
Grant Amount |
Project Period |
|
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1 |
R825702
Centers - Main center abstract - Denver Children’s Environmental Health Center - Environmental Determinants of Airway Disease in Children |
Immunologic Basis of Environmental Lung Disease |
Mason, Robert J. Gelfand, Erwin Rabinovitch, Nathan White, Carl W. - Principal Investigators listed are sub-PIs determined by the center. |
Row 1: Final
|
Row 1 Total Pubs:
132 Row 1 Journals: 110 Row 1 Books: 1 |
National Jewish Medical and Research Center | Chung, Serena | $7,269,177 |
February 16, 1998 - February 28, 2003 (Extended to February 28, 2004) |
2 |
R827353
Centers - Main center abstract - Health Effects Institute (2015 - 2020) |
Ambient Particle Health Effects: Exposure, Susceptibility, and Mechanisms |
Koutrakis, Petros Adamkiewicz, Gary Bateson, Thomas F Brain, Joseph D. Brown, Kathleen Ward Burge, Harriet A. Butler, James Preston Catalano, Paul Christiani, David Coull, Brent Demokritou, Philip Dockery, Douglas W. Dubowsky, S. Evans, John S. Fox, L. Godleski, John J. Gold, Diane R. Gonzalez-Flecha, Beatriz Graham, John Hammitt, James K. Kelsey, Karl Kobzik, Lester Laden, Francine Lawrence, Joy Levy, Jonathan Luttmann-Gibson, Heike Mark, Teresa O'Neill, M. Park, S. Ruiz, Pablo Sarnat, Jeremy Schwartz, Joel Smythe, Alice Speizer, Frank E. Spengler, John D. Stevens, G. Stone, Peter Suh, Helen H. Tsuda, Akira Vallarino, Jose Verrier, Richard Ware, James Wellenius, Gregory Wheeler, A. Wilson, A. Wolfson, Jack M. Zanobetti, Antonella - Principal Investigators listed are sub-PIs determined by the center. |
Row 2: Final
|
Row 2 Total Pubs:
206 Row 2 Journals: 203 -- Row 2: No Books -- |
Harvard University | Chung, Serena | $7,747,040 |
June 01, 1999 - May 31, 2005 (Extended to May 31, 2006) |
3 |
R831725
Centers - Main center abstract - Health Effects Institute (2015 - 2020) |
Metal Mixtures and Children’s Health |
Brain, Joseph D. Hu, Howard Backus, Ann Hatley, Earl Jim, Rebecca Schwartz, Joel Shine, James P. Spengler, John D. - Principal Investigators listed are sub-PIs determined by the center. |
Row 3: 2004
|
Row 3 Total Pubs:
32 Row 3 Journals: 25 Row 3 Books: 1 |
Harvard University | Callan, Richard | $7,894,185 |
June 01, 2004 - May 31, 2009 (Extended to May 31, 2011) |
4 |
R832416
Centers - Main center abstract - Harvard Particle Center |
Harvard Particle Center |
Koutrakis, Petros Brook, Jeffrey R. Brook, Robert D. Coull, Brent Demokritou, Philip Dockery, Douglas W. Godleski, John J. Gold, Diane R. Gonzalez-Flecha, Beatriz Schwartz, Joel Silverman, Frances Sparrow, David Speizer, Frank E. Stone, Peter Suh, Helen H. Vokonas, Pantel - Principal Investigators listed are sub-PIs determined by the center. |
Row 4: 2006
|
Row 4 Total Pubs:
196 Row 4 Journals: 190 -- Row 4: No Books -- |
Harvard University, Boston University, Brigham and Women’s Hospital, University of Michigan, University of Toronto | Chung, Serena | $7,999,609 |
October 01, 2005 - September 30, 2010 (Extended to September 30, 2011) |
5 |
R834513
Centers - Main center abstract - Center for the Health Assessment of Mothers and Children of Salinas - UC Berkeley School of Public Health: CHAMACOS Office, Berkeley, CA |
Center for Children’s Environmental Health and DiseasePreventionResearch (P01) (joint EPA and NIEHS) - CHAMACOS |
Eskenazi, Brenda Arora, Manish Barcellos, Lisa Barlow, Janice Blum, Arlene Bradman, Asa Chevrier, Jonathan Crinella, Frank Eisen, Ellen Fenster, Laura Harley, Kim Harnly, Martha Holland, Nina T. Hubbard, Alan Jerrett, Michael Johnson, Caroline Lustig, Robert McKone, Thomas Minkler, Meredith Molitor, John Rosas, Lisa Goldman Salvatore, Alicia Salvatore, Alicia L. Sjodin, Andreas Smith, Donald Wallerstein, Nina - Principal Investigators listed are sub-PIs determined by the center. |
Row 5: 2010
|
Row 5 Total Pubs:
514 Row 5 Journals: 156 -- Row 5: No Books -- |
University of California - Berkeley, Centers for Disease Control and Prevention, Harvard University, Natividad Medical Foundation, Oregon State University, University of California - Santa Cruz, University of New Mexico, ZERO Breast Cancer | Hahn, Intaek | $3,585,582 |
August 01, 2009 - July 31, 2014 (Extended to July 31, 2017) |
6 |
R834515
Centers - Main center abstract - Denver Childrens Environmental Health Center - Environmental Determinants of Airway Disease in Children |
Endotoxin Exposure and Asthma in Children |
Schwartz, David A. Correll, Kelly Covar, Ronina A Crooks, James L Dakhama, Azzeddine Faino, Anna Fingerlin, Tasha Forssen, Anna Gabehart, Kelsa Litonjua, Augusto A. Liu, Andrew H. Loader, Joan Martyny, John W. Murphy, Amy J Oakes, Judy Rabinovitch, Nathan Sordillo, Joanne Strand, Mathew J. Szefler, Stanley Van Dyke, Michael V. White, Carl W. Yang, Ivana Yang, Jing - Principal Investigators listed are sub-PIs determined by the center. |
Row 6: 2010
|
Row 6 Total Pubs:
51 Row 6 Journals: 30 -- Row 6: No Books -- |
National Jewish Health, National Jewish Medical and Research Center, Channing Laboratory, Harvard Medical School, Harvard University, Tri-County Health Department, CO | Hahn, Intaek | $1,897,209 |
June 22, 2010 - June 21, 2015 (Extended to June 21, 2017) |
7 |
R834515C001
Centers - This is a subproject of the Denver Childrens Environmental Health Center - Environmental Determinants of Airway Disease in Children (R834515) |
Endotoxin Exposure and Asthma in Children |
Schwartz, David A. Covar, Ronina A Crooks, James L Fingerlin, Tasha Forssen, Anna Litonjua, Augusto A. Liu, Andrew H. Rabinovitch, Nathan Sordillo, Joanne Szefler, Stanley Van Dyke, Michael V. - Principal Investigators listed are sub-PIs determined by the center. |
Row 7: 2010
|
Row 7 Total Pubs:
23 Row 7 Journals: 14 -- Row 7: No Books -- |
Boston University, National Jewish Health, Harvard University, National Jewish Medical and Research Center |
EPA Project Officer(s) for Denver Childrens Environmental Health Center - Environmental Determinants of Airway Disease in Children Grant Number R834515: Hahn, Intaek |
Refer to main center abstract (R834515) for funding details. |
June 22, 2010 - June 21, 2015 (Extended to June 21, 2017) |
8 |
R834515C002
Centers - This is a subproject of the Denver Childrens Environmental Health Center - Environmental Determinants of Airway Disease in Children (R834515) |
Environmental Determinants of Early Host Response to RSV |
Schwartz, David A. Correll, Kelly Dakhama, Azzeddine Gabehart, Kelsa Loader, Joan White, Carl W. Yang, Jing - Principal Investigators listed are sub-PIs determined by the center. |
Row 8: 2010
|
Row 8 Total Pubs:
23 Row 8 Journals: 13 -- Row 8: No Books -- |
Boston University, National Jewish Health, Harvard University, National Jewish Medical and Research Center, University of Colorado at Denver, University of North Carolina at Charlotte |
EPA Project Officer(s) for Denver Childrens Environmental Health Center - Environmental Determinants of Airway Disease in Children Grant Number R834515: Hahn, Intaek |
Refer to main center abstract (R834515) for funding details. |
June 22, 2010 - June 21, 2015 (Extended to June 21, 2017) |
9 |
R834515C003
Centers - This is a subproject of the Denver Childrens Environmental Health Center - Environmental Determinants of Airway Disease in Children (R834515) |
Environmental Determinants of Host Defense |
Schwartz, David A. Eyring, Ken Huber, Jonathan Oakes, Judy Yang, Ivana - Principal Investigators listed are sub-PIs determined by the center. |
Row 9: 2014
|
Row 9 Total Pubs:
23 Row 9 Journals: 14 -- Row 9: No Books -- |
Boston University, National Jewish Health, Harvard University, University of Colorado at Denver |
EPA Project Officer(s) for Denver Childrens Environmental Health Center - Environmental Determinants of Airway Disease in Children Grant Number R834515: Hahn, Intaek |
Refer to main center abstract (R834515) for funding details. |
September 01, 2009 - August 31, 2014 (Extended to June 21, 2017) |
10 |
R834593
Centers - Main center abstract - Water Innovation Network for Sustainable Small Systems |
Novel Methods to Assess Effects of Bisphenol A (BPA) & Phthalates on Child Development |
Schantz, Susan L. Aguiar, Andrea Baillargeon, Renee L. Flaws, Jodi Gardnier, Joseph Juraska, Janice Korrick, Susan A. Yao, Humphrey Yi, Sandra James - Principal Investigators listed are sub-PIs determined by the center. |
Row 10: 2010
|
Row 10 Total Pubs:
12 Row 10 Journals: 5 -- Row 10: No Books -- |
University of Illinois Urbana-Champaign, Harvard University, Michigan State University | Hahn, Intaek | $1,094,951 |
February 15, 2010 - February 14, 2014 |
11 |
R834596
Centers - Main center abstract - UC Berkeley/Stanford Children’s Environment Health Center |
Berkeley/Stanford Children’s Environmental Health Center |
Hammond, S. Katharine Balmes, John R. Eisen, Ellen Gale, Sara L Gould, Jeffery Hubbard, Alan Lurmann, Fred Mann, Jennifer Mortimer, Kathleen Nadeau, Kari Noth, Elizabeth Padula, Amy Shaw, Gary M. Tager, Ira - Principal Investigators listed are sub-PIs determined by the center. |
Row 11: 2010
|
Row 11 Total Pubs:
49 Row 11 Journals: 15 -- Row 11: No Books -- |
University of California - Berkeley, Harvard University, Sonoma Technology, Inc., Stanford University, University of California - San Francisco | Callan, Richard | $1,091,783 |
May 07, 2010 - May 06, 2013 (Extended to May 06, 2014) |
12 |
R834798
Centers - Main center abstract - Center for Integrative Research on Childhood Leukemia and the Environment - 2015 |
Air Pollution Mixtures: Health Effects Across Life Stages |
Koutrakis, Petros Bell, Michelle L. Coull, Brent Diaz, Edgar Dominici, Francesca Gillman, Matthew Godleski, John J. Gold, Diane R. Lawrence, Joy Mittleman, Murray Oken, Emily Schwartz, Joel Wolfson, Michael Zanobetti, Antonella - Principal Investigators listed are sub-PIs determined by the center. |
Row 12: 2010
|
Row 12 Total Pubs:
399 Row 12 Journals: 342 -- Row 12: No Books -- |
Harvard University, Yale University | Chung, Serena | $7,997,561 |
January 01, 2011 - December 31, 2015 (Extended to December 31, 2016) |
13 |
R836156
Centers - Main center abstract - Health Effects Institute (2015 - 2020) |
Center for Research on Environmental and Social Stressors in Housing across the Life Course |
Laden, Francine Adamkiewicz, Gary Fabian, Maria Patricia Lane, Kevin J Levy, Jonathan Scammell, Madeleine Kangsen Sprengler, John D Zanobetti, Antonella - Principal Investigators listed are sub-PIs determined by the center. |
Row 13: 2016
|
Row 13 Total Pubs:
90 Row 13 Journals: 25 -- Row 13: No Books -- |
Harvard University, Boston University | Callan, Richard | $1,500,000 |
July 01, 2015 - June 30, 2020 (Extended to June 30, 2021) |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.