Grantee Research Project Results
Research Centers
Environmental Determinants of Airway Disease in Children
3D ARRAY TECHNOLOGY LLC
This Center is looking into possible causes of asthma and other respiratory diseases, which are the most common chronic childhood illnesses. Symptoms can include coughing and difficulty breathing, dramatically affecting a child’s quality of life. Environmental exposures may impair the lung’s ability to respond to irritants and increase a child’s risk of developing respiratory disease. Researchers are focusing on ozone and bacterial endotoxin, which are common environmental exposures and can be inhaled. Ozone is an air pollutant and a component of smog while endotoxins are part of the cell wall of some bacteria, released into the air when the bacteria die. Since both of these agents can affect immune system response, researchers believe that such exposures could alter the response of the innate and developing immune system, leading to lung inflammation and impaired lung function, making a child more susceptible to getting asthma or other lung diseases.
Center Publications:
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View Projects in Tabular Format
Main Center Abstract and Reports:
Ambient Particle Health Effects: Exposure, Susceptibility, and Mechanisms
Immunologic Basis of Environmental Lung Disease
Harvard Particle Center
Metal Mixtures and Children’s Health
- Original Abstract
- 2006 Progress Report
- 2007 Progress Report
- 2008 Progress Report
- 2009 Progress Report
- 2010 Progress Report
- Final Report
Center for Children’s Environmental Health and DiseasePreventionResearch (P01) (joint EPA and NIEHS) - CHAMACOS
- Original Abstract
- 2004 Progress Report
- 2005 Progress Report
- 2007 Progress Report
- 2009 Progress Report
- Final Report
Endotoxin Exposure and Asthma in Children
- Original Abstract
- 2010 Progress Report
- 2011 Progress Report
- 2012 Progress Report
- 2013 Progress Report
- 2014 Progress Report
- 2015 Progress Report
- 2016 Progress Report
- Final Report
Novel Methods to Assess Effects of Bisphenol A (BPA) & Phthalates on Child Development
- Original Abstract
- 2010 Progress Report
- 2011 Progress Report
- 2012 Progress Report
- 2013 Progress Report
- 2014 Progress Report
- 2015 Progress Report
- Final Report
Berkeley/Stanford Children’s Environmental Health Center
Air Pollution Mixtures: Health Effects Across Life Stages
Center for Research on Environmental and Social Stressors in Housing across the Life Course
- Original Abstract
- 2010 Progress Report
- 2011 Progress Report
- 2012 Progress Report
- 2013 Progress Report
- 2014 Progress Report
- 2015 Progress Report
- 2016 Progress Report
- Final Report
Center Research Projects:
R834515C001 - Endotoxin Exposure and Asthma in Children
R834515C002 - Environmental Determinants of Early Host Response to RSV
R834515C003 - Environmental Determinants of Host Defense
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.