Skip to main content
U.S. flag

An official website of the United States government

Here’s how you know

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

HTTPS

Secure .gov websites use HTTPS
A lock (LockA locked padlock) or https:// means you have safely connected to the .gov website. Share sensitive information only on official, secure websites.

  • Environmental Topics
  • Laws & Regulations
  • Report a Violation
  • About EPA
Contact Us

Grantee Research Project Results

Research Centers
Midwest Hazardous Substance Research Center

Purdue University - Main Campus

The mission of Midwest HSRC is to support collaborative research and technology transfer efforts within EPA regions 3,5, and 7 with a focus on integrated low cost remediation technologies that improve risk management by removing contaminants from the environment and restoring ecosystem quality, thereby enhancing site redevelopment options. This mission will be accomplished through an extensive university/EPA/industry partnership involving a multidisciplinary research program. The Midwest HSRC partnership arrangements are well developed, with many industrial-matching commitments. Comprehensive technology transfer and outreach programs will integrate new knowledge and technology into use by industry, communities, and government. The Midwest HSRC also has a strong commitment to diversity issues and will provide opportunities for minority students and faculty from three minority institutions to become involved in Midwest HSRC research, outreach, and technology transfer programs.

Center Publications:

Views: All publications Selected publication types Journal articles Publications submitted after final report

View Projects in Tabular Format

Main Center Abstract and Reports:

Atlantic Coast Environmental Indicators Consortium
  • Original Abstract
  • 2001 Progress Report
  • 2002 Progress Report
  • 2003 Progress Report
  • 2004 Progress Report
  • Final Report
Southern California Particle Center and Supersite (SCPCS)
  • Original Abstract
  • 2003 Progress Report
  • 2004 Progress Report
  • Final Report
Center for the Study of Prevalent Neurotoxicants in Children
  • Original Abstract
  • 2003 Progress Report
  • 2004 Progress Report
  • 2005 Progress Report
  • Final Report
Great Plains/Rocky Mountain Hazardous Substance Research Centers
  • Original Abstract
Midwest Hazardous Substance Research Center
  • Original Abstract
  • 2002 Progress Report
  • 2003 Progress Report
  • Final Report
Midwest Hazardous Substance Research Center
  • Original Abstract
  • Final Report
Southern California Particle Center (SCPC)
  • Original Abstract
  • 2006 Progress Report
  • 2007 Progress Report
  • 2008 Progress Report
  • 2009 Progress Report
  • 2010 Progress Report
  • Final Report
The Center for Advancing Microbial Risk Assessment (CAMRA)
  • Original Abstract
  • 2007 Progress Report
  • Final Report
The Center for Environmental Implications of Nanotechnology (CEINT)
  • Original Abstract
Novel Methods to Assess Effects of Bisphenol A (BPA) & Phthalates on Child Development
  • Original Abstract
  • 2010 Progress Report
  • 2011 Progress Report
  • 2012 Progress Report
  • Final Report
Great Lakes Air Center for Integrative Environmental Research (GLACIER)
  • Original Abstract
  • 2011 Progress Report
  • 2012 Progress Report
  • 2013 Progress Report
  • 2014 Progress Report
  • 2015 Progress Report
  • 2016 Progress Report
  • Final Report

Center Research Projects:

R828112C042 - Does Inhalation of Methanol Vapor Affect Human Neurobehavior?

  • Original Abstract
  • Final Report

R828112C043 - Human Responses to Nitrogen Dioxide

  • Original Abstract

R828112C044 - The Role of Inflammation in Ozone-Induced Lung Injury

  • Original Abstract

R828112C045 - How Does Exercise Affect the Dose of Inhaled Air Pollutants?

  • Original Abstract

R828112C046 - How Do Chemicals in Diesel Engine Exhaust Damage DNA?

  • Original Abstract
  • Final Report

R828112C047 - Effect of Nitrogen Dioxide on Bacterial Respiratory infectionin Mice

  • Original Abstract
  • Final Report

R828112C048 - Effects of Ozone Exposure on Airway Epithelium

  • Original Abstract
  • Final Report

R828112C049 - Inhalation of Aldehydes and Effects on Breathing

  • Original Abstract
  • Final Report

R828112C050 - Does Ozone Cause Precancerous Changes in Cells?

  • Original Abstract
  • Final Report

R828112C051 - Effects of Formaldehyde on Human Airway Epithelial Cells Exposed in a Novel Culture System

  • Original Abstract
  • Final Report

R828112C052 - Carbon Monoxide and Cardiac Arrhythmias

  • Original Abstract
  • Final Report

R828112C053 - Effects of Formaldehyde and Particle-Bound Formaldehyde on Lung Macrophage Functions

  • Original Abstract
  • Final Report

R828112C054 - Mechanisms for Protecting Lung Epithelial Cells Against Oxidant Injury

  • Original Abstract
  • Final Report

R828112C055 - Relationship of Nitropyrene-Derived DNA Adducts to Carcinogenesis

  • Original Abstract
  • Final Report

R828112C056 - Particle Trap Effects on Heavy-Duty Diesel Engine Emissions

  • Original Abstract
  • Final Report

R828112C057 - Carbon Monoxide and Atherosclerosis

  • Original Abstract
  • Final Report

R828112C058 - Nitrogen Dioxide and Respiratory Illness in Children

  • Original Abstract
  • Final Report

R828112C059 - Noninvasive Methods for Measuring Ventilation in Mobile Subjects

  • Original Abstract
  • Final Report

R828112C060 - Oxidant Air Pollutants and Lung Cancer: An Animal Model

  • Original Abstract
  • Final Report

R828112C061 - Detection of Carcinogen-DNA Adducts: Development of New Methods

  • Original Abstract
  • Final Report

R828112C062 - Effects of Carbon Monoxide on Heart Muscle Cells

  • Original Abstract
  • Final Report

R828112C063 - Development of Personal Ozone Samplers: Three Approaches

  • Original Abstract
  • Final Report

R828112C064 - Development of Biomarkers to Monitor Carcinogen Exposure

  • Original Abstract
  • Final Report

R828112C065 - Effects of Prolonged Ozone Inhalation on Collagen Structure and Content in Rat Lungs

  • Original Abstract
  • Final Report

R828112C065II - Prolonged Ozone Exposure and the Contractile Properties of Isolated Rat Airways

  • Original Abstract
  • Final Report

R828112C065III - Changes in Complex Carbohydrate Content and Structure in Rat Lungs Caused by Prolonged Ozone Inhalation

  • Original Abstract

R828112C065IV - Genetic Control of Connective Tissue Protein Synthesis After Prolonged Ozone Inhalation

  • Original Abstract

R828112C065V - Pulmonary Function Alterations in Rats After Chronic Ozone Inhalation

  • Original Abstract

R828112C065VII - Prolonged Ozone Exposure Leads to Functional and Structural Changes in the Rat Nose

  • Original Abstract

R828112C065VIII - IX - Studies of Changes in Lung Structure and Enzyme Activitiesin Rats After Prolonged Exposure to Ozone

  • Original Abstract
  • Final Report

R828112C065X - An Innovative Approach to Analyzing Multiple Experimental Outcomes: A Case Study of Rats Exposed to Ozone

  • Original Abstract

R828112C065XI - The Consequences of Prolonged Inhalation of Ozone on Rats: An Integrative Summary of the Results of Eight Collaborative Studies

  • Original Abstract
  • Final Report

R828112C066 - Interactive Effects of Nitropyrenes in Diesel Exhaust

  • Original Abstract
  • Final Report

R828112C067 - Detection of Formaldehyde–DNA Adducts: Development of New Methods

  • Original Abstract
  • Final Report

R828112C068I - Comparison of the Carcinogenicity of Diesel Exhaust and Carbon Black in Rat Lungs

  • Original Abstract
  • Final Report

R828112C068II - An Investigation of DNA Damage in the Lungs of Rats Exposed to Diesel Exhaust

  • Original Abstract
  • Final Report

R828112C068III - No Evidence For Genetic Mutations Found In Lung Tumors From Rats Exposed To Diesel Exhaust or Carbon Black

  • Original Abstract
  • Final Report

R828112C069 - Noninvasive Determination of Respiratory Ozone Absorption: The Bolus-Response Method

  • Original Abstract
  • Final Report

R828112C070 - The Effects of Inhaled Oxidants and Acid Aerosols on Pulmonary Function

  • Original Abstract
  • Final Report

R828112C071 - Biochemical Consequences of Ozone Reacting with Membrane Fatty Acids

  • Original Abstract
  • Final Report

R828112C072 - DNA Mutations in Rats Treated with a Carcinogen Present in Diesel Exhaust

  • Original Abstract
  • Final Report

R828112C073 - Developmental Neurotoxicity of Inhaled Methanol in Rats

  • Original Abstract
  • Final Report

R828112C074 - Methanol Distribution in Non Pregnant and Pregnant Rodents

  • Original Abstract
  • Final Report

R828112C075 - Is Increased Mortality Associated with Ozone Exposure in Mexico City?

  • Original Abstract
  • Final Report

R828112C076 - Effects of Fuel Modification and Emission Control Devices on Heavy-Duty Diesel Engine Emissions

  • Original Abstract
  • Final Report

R828112C077 - Metabolic Studies in Monkeys Exposed to Methanol Vapors

  • Original Abstract
  • Final Report

R828112C078 - Effects of Ozone on Pulmonary Function and Airway Inflammation in Normal and Potentially Sensitive Human Subjects

  • Original Abstract
  • Final Report

R828112C079 - Improvement of a Respiratory Ozone Analyzer

  • Original Abstract
  • Final Report

R828112C080 - Mechanism of Oxidative Stress from Low Levels of Carbon Monoxide

  • Original Abstract
  • Final Report

R828112C081 - Long-Term Exposure to Ozone: Development of Methods to Estimate Past Exposures and Health Outcomes

  • Original Abstract
  • Final Report

R828112C082 - Effects of Ambient Ozone on Healthy, Wheezy, and Asthmatic Children

  • Original Abstract
  • Final Report

R828112C083 - Daily Changes in Oxygen Saturation and Pulse Rate Associated with Particulate Air Pollution and Barometric Pressure

  • Original Abstract
  • Final Report

R828112C084 - Evaluation of The Potential Health Effects of the Atmospheric Reaction Products of Polycyclic Aromatic Hydrocarbons

  • Original Abstract
  • Final Report

R828112C085 - Mechanisms of Response to Ozone Exposure: The Role of Mast Cells in Mice

  • Original Abstract
  • Final Report

R828112C086 - Statistical Methods for Epidemiologic Studies of the Health Effects of Air Pollution

  • Original Abstract
  • Final Report

R828112C087 - Development of New Methods to Measure Benzene Biomarkers

  • Original Abstract
  • Final Report

R828112C088 - Alveolar Changes in Rat Lungs After Long-Term Exposure to Nitric Oxide

  • Original Abstract
  • Final Report

R828112C089 - Effects of Prenatal Exposure to Inhaled Methanol on Nonhuman Primates and Their Infant Offspring

  • Original Abstract
  • Final Report

R828112C090 - A Pilot Study of Potential Biomarkers of Ozone Exposure

  • Original Abstract
  • Final Report

R828112C091 - Effects of Concentrated Ambient Particles on the Cardiac and Pulmonary Systems of Dogs

  • Original Abstract
  • Final Report

R828112C092 - Cancer, Mutations, and Adducts in Rats and Mice Exposed to Butadiene and Its Metabolites

  • Original Abstract
  • Final Report

R828112C093 - Effects of Concentrated Ambient Particles in Rats and Hamsters: An Exploratory Study

  • Original Abstract
  • Final Report

R828112C094I - The National Morbidity, Mortality, and Air Pollution Study: Methods and Methodologic Issues

  • Original Abstract
  • Final Report

R828112C094II - The National Morbidity, Mortality, and Air Pollution Study: Morbidity and Mortality from Air Pollution in the United States

  • Original Abstract
  • Final Report

R828112C095 - Association of Particulate Matter Components with Daily Mortality and Morbidity in Urban Populations

  • Original Abstract
  • Final Report

R828112C096 - Acute Pulmonary Effects of Ultrafine Particles in Rats and Mice

  • Original Abstract
  • Final Report

R828112C097 - Identifying Subgroups of the General Population That May Be Susceptible to Short-Term Increases in Particulate Air Pollution

  • Original Abstract
  • Final Report

R828112C098 - Daily Mortality and Fine and Ultrafine Particles in Erfurt, Germany

  • Original Abstract
  • Final Report

R828112C099 - A Case-Crossover Analysis of Fine Particulate Matter Air Pollution and Out-of-Hospital Sudden Cardiac Arrest

  • Original Abstract
  • Final Report

R828112C100 - Effects of Mexico City Air on Rat Nose

  • Original Abstract
  • Final Report

R828112C101 - Penetration of Lung Lining and Clearance of Particles Containing Benzo[a]pyrene

  • Original Abstract
  • Final Report

R828112C102 - Metabolism of Ether Oxygenates Added to Gasoline

  • Original Abstract
  • Final Report

R828112C103 - Characterization and Mechanisms of Chromosomal Alterations Induced by Benzene in Mice and Humans

  • Original Abstract
  • Final Report

R828112C104 - Acute Cardiovascular Effects in Rats from Exposure to Urban Ambient Particles

  • Original Abstract
  • Final Report

R828112C105 - Genetic Differences in Induction of Acute Lung Injury and Inflammation in Mice

  • Original Abstract
  • Final Report

R828112C106 - Effects on Mice of Exposure to Ozone and Ambient Particle Pollution

  • Original Abstract
  • Final Report

R828112C107 - Emissions from Diesel and Gasoline Engines Measured in Highway Tunnels

  • Original Abstract
  • Final Report

R828112C108 - Case-Cohort Study of Styrene Exposure and Ischemic Heart Disease Investigators

  • Original Abstract
  • Final Report

R828112C110 - Effects of Metals Bound to Particulate Matter on Human Lung Epithelial Cells

  • Original Abstract

R828112C111 - Effect of Concentrated Ambient Particulate Matter on Blood Coagulation Parameters in Rats

  • Original Abstract

R828112C112 - Health Effects of Acute Exposure to Air Pollution

  • Original Abstract

R828112C113 - Benzene Metabolism in Rodents at Doses Relevant to Human Exposure from Urban Air

  • Original Abstract
  • Final Report

R828112C114 - A Personal Particle Speciation Sampler

  • Original Abstract

R828112C115 - Validation and Evaluation of Biomarkers in Workers Exposed to Benzene in China

  • Original Abstract
  • Final Report

R828112C116 - Biomarkers in Czech Workers Exposed to 1,3-Butadiene: A Transitional Epidemiologic Study

  • Original Abstract

R828112C117 - Peroxides and Macrophages in the Toxicity of Fine Particulate Matter in Rats

  • Original Abstract

R828112C118 - Controlled Exposures of Healthy and Asthmatic Volunteers to Concentrated Ambient Particles in Metropolitan Los Angeles

  • Original Abstract

R828112C119 - Manganese Toxicokinetics at the Blood-Brain Barrier

  • Original Abstract

R828112C120 - Effects of Exposure to Concentrated Ambient Particles from Detroit Air on Healthy Rats and Rats with Features of Asthma or Mild Bronchitis

  • Original Abstract

R828112C121 - Field Evaluation of Nanofilm Detectors for Measuring Acidic Particles in Indoor and Outdoor Air

  • Original Abstract

R828112C123 - Time-Series Analysis of Air Pollution and Mortality: A Statistical Review

  • Original Abstract

R828112C126 - Effects of Exposure to Ultrafine Carbon Particles in Healthy Subjects and Subjects with Asthma

  • Original Abstract

R828112C128 - Neurogenic Responses of Rat Lung to Diesel Exhaust

  • Original Abstract

R828112C130-I - Relationships of Indoor, Outdoor, and Personal Air (RIOPA). Part I. Collection Methods and Descriptive Analyses

  • Original Abstract

R828112C132 - An Updated Study of Mortality Among North American Synthetic Rubber Industry Workers

  • Original Abstract

R828770C001 - Technical Outreach Services for Communities

  • Original Abstract
  • 2002 Progress Report
  • 2003 Progress Report

R828770C002 - Technical Outreach Services for Native American Communities

  • Original Abstract

R828770C003 - Sustainable Remediation

  • Original Abstract
  • 2002 Progress Report
  • 2003 Progress Report

R828770C004 - Incorporating Natural Attenuation Into Design and Management Strategies For Contaminated Sites

  • Original Abstract
  • 2002 Progress Report
  • 2003 Progress Report

R828770C005 - Metals Removal by Constructed Wetlands

  • Original Abstract
  • 2002 Progress Report
  • 2003 Progress Report

R828770C006 - Adaptation of Subsurface Microbial Biofilm Communities in Response to Chemical Stressors

  • Original Abstract
  • 2002 Progress Report
  • 2003 Progress Report

R828770C007 - Dewatering, Remediation, and Evaluation of Dredged Sediments

  • Original Abstract
  • 2002 Progress Report
  • 2003 Progress Report

R828770C008 - Interaction of Various Plant Species with Microbial PCB-Degraders in Contaminated Soils

  • Original Abstract
  • 2002 Progress Report
  • 2003 Progress Report

R828770C009 - Microbial Indicators of Bioremediation Potential and Success

  • Original Abstract
  • 2002 Progress Report

Top of Page

The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

Site Navigation

  • Grantee Research Project Results Home
  • Grantee Research Project Results Basic Search
  • Grantee Research Project Results Advanced Search
  • Grantee Research Project Results Fielded Search
  • Publication search
  • EPA Regional Search

Related Information

  • Search Help
  • About our data collection
  • Research Grants
  • P3: Student Design Competition
  • Research Fellowships
  • Small Business Innovation Research (SBIR)
Contact Us to ask a question, provide feedback, or report a problem.
Last updated April 28, 2023
United States Environmental Protection Agency

Discover.

  • Accessibility
  • Budget & Performance
  • Contracting
  • EPA www Web Snapshot
  • Grants
  • No FEAR Act Data
  • Plain Writing
  • Privacy
  • Privacy and Security Notice

Connect.

  • Data.gov
  • Inspector General
  • Jobs
  • Newsroom
  • Open Government
  • Regulations.gov
  • Subscribe
  • USA.gov
  • White House

Ask.

  • Contact EPA
  • EPA Disclaimers
  • Hotlines
  • FOIA Requests
  • Frequent Questions

Follow.