Grantee Research Project Results
Publications Details for Grant Number R835738C005
Integrating Liver, Kidney and Testis Nanomaterial Toxicity using the Adverse Outcome Pathway Approach
RFA:
Organotypic Culture Models for Predictive Toxicology Center (2013)
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| Reference Type | Reference Title | Journal | Author | Citation | Progress Report Year | Document Sources |
|---|---|---|---|---|---|---|
| Abstract | Testicular cells co-culture as an alternative model for male reproductive toxicity. | None | Faustman EM | Faustman EM. Testicular cells co-culture as an alternative model for male reproductive toxicity. The Toxicologist 2017;151(1):144 (Abstract 1613). |
R835738 (2017) R835738C004 (2017) R835738C005 (2017) |
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| Journal Article | Liver and kidney on chips: micro-physiological models to understand transporter function. | CLINICAL PHARMACOLOGY & THERAPEUTICS | Chang S-Y, Weber EJ, Van Ness KP, Eaton DL, Kelly EJ | Chang S-Y, Weber EJ, Van Ness KP, Eaton DL, Kelly EJ. Liver and kidney on chips: microphysiological models to understand transporter function. Clinical Pharmacology & Therapeutics 2016;100(5):464-478. |
R835738 (2016) R835738 (2017) R835738C002 (2016) R835738C003 (2016) R835738C003 (2017) R835738C005 (2017) |
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| Journal Article | Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity. | None | Chang S-Y, Weber EJ, Sidorenko VS, Chapron A, Yeung CK, Gao C, Mao Q, Shen D, Wang J, Rosenquist TA, Dickman KG, Neumann T, Grollman AP, Kelly EJ, Himmelfarb J, Eaton DL | Chang S-Y, Weber EJ, Sidorenko VS, Chapron A, Yeung CK, Gao C, Mao Q, Shen D, Wang J, Rosenquist TA, Dickman KG, Neumann T, Grollman AP, Kelly EJ, Himmelfarb J, Eaton DL. Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity. JCI Insight 2017;2(22):e95978 (15 pp.). |
R835738C003 (2017) R835738C005 (2017) |
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| Journal Article | Short-term inhalation study of graphene oxide nanoplates. | None | Kim YH, Jo MS, Kim JK, Shin JH, Baek JE, Park HS, An HJ, Lee JS, Kim BW, KH Kim, Ahn KH, Jeon KS, Oh SM, Lee JH, Workman T, Faustman EM, Yu IJ | Kim YH, Jo MS, Kim JK, Shin JH, Baek JE, Park HS, An HJ, Lee JS, Kim BW, Kim HP, Ahn KH, Jeon KS, Oh SM, Lee JH, Workman T, Faustman EM, Yu IJ. Short-term inhalation study of graphene oxide nanoplates. Nanotoxicology 2018;12(3):224-238. |
R835738 (2017) R835738C001 (2018) R835738C004 (2018) R835738C005 (2018) |
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| Journal Article | FutureTox II: in vitro data and in silico models for predictive toxicology. | TOXICOLOGICAL SCIENCES | Knudsen TB, Keller DA, Sander M, Carney EW, Doerrer NG, Eaton DL, Fitzpatrick SC, Hastings KL, Mendrick DL, Tice RR, Watkins PB, Whelan M | Knudsen TB, Keller DA, Sander M, Carney EW, Doerrer NG, Eaton DL, Fitzpatrick SC, Hastings KL, Mendrick DL, Tice RR, Watkins PB, Whelan M. FutureTox II: in vitro data and in silico models for predictive toxicology. Toxicological Sciences 2015;143(2):256-267. |
R835738 (2016) R835738C005 (2017) |
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| Journal Article | Characterization of 3D embryonic C57BL/6 and A/J mouse midbrain micromass in vitro culture systems for developmental neurotoxicity testing. | None | Park JJ, Weldon BA, Hong S, Workman T, Griffith WC, Park JH, Faustman EM | Park JJ, Weldon BA, Hong S, Workman T, Griffith WC, Park JH, Faustman EM. Characterization of 3D embryonic C57BL/6 and A/J mouse midbrain micromass in vitro culture systems for developmental neurotoxicity testing. Toxicology In Vitro 2018;48:33-44. |
R835738 (2017) R835738C001 (2018) R835738C004 (2018) R835738C005 (2018) |
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| Journal Article | Developing the regulatory utility of the exposome: mapping exposures for risk assessment through lifestage exposome snapshots (LEnS). | ENVIRONMENTAL HEALTH PERSPECTIVES | Shaffer R, Smith MN, Faustman EM | Shaffer R, Smith MN, Faustman EM. Developing the regulatory utility of the exposome: mapping exposures for risk assessment through Lifestage Exposome Snapshots (LEnS). Environmental Health Perspectives 2017;123(8):085003 (8 pp.). |
R835738 (2017) R835738C004 (2018) R835738C005 (2017) |
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| Journal Article | A toxicological framework for the prioritization of Children’s Safe Product Act data. | INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH | Smith MN, Grice J, Cullen A, Faustman EM | Smith MN, Grice J, Cullen A, Faustman EM. A toxicological framework for the prioritization of Children’s Safe Product Act data. International Journal of Environmental Research and Public Health 2016;13(4):431 (24 pp.). |
R834514 (Final) R835738 (2016) R835738 (2017) R835738C005 (2015) R835738C005 (2016) R835738C005 (2017) |
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| Journal Article | Microphysiological systems to assess nonclinical toxicity. | None | Van Ness KP, Chang SY, Weber EJ, Zumpano D, Eaton DL, Kelly EJ | Van Ness KP, Chang SY, Weber EJ, Zumpano D, Eaton DL, Kelly EJ. Microphysiological systems to assess nonclinical toxicity. Current Protocols in Toxicology 2017;73(1):14.18.1-14.18.28. |
R835738 (2017) R835738C001 (2018) R835738C002 (2017) R835738C002 (2018) R835738C004 (2018) R835738C005 (2017) |
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| Journal Article | Functional coupling of human microphysiology systems: intestine, liver, kidney proximal tubule, blood-brain barrier and skeletal muscle. | None | Vernetti LA, Gough A, Baetz N, Blutt S, Broughman JR, Brown JA,Foulke-Abel J, Hasan N, In J, Kelly E, Kovbasnjuk O, Repper J,Senutovitch N, Stabb J, Yeung C, Zachos NC, Donowitz M, Estes M,Himmelfarb J, Truskey G, Wikswo JP, Taylor DL. | Vernetti L, Gough A, Baetz N, Blutt S, Broughman JR, Brown JA, Foulke-Abel J, Hasan N, In J, Kelly E, Kovbasnjuk O, Repper J, Senutovitch N, Stabb J, Yeung C, Zachos NC, Donowitz M, Estes M, Himmelfarb J, Truskey G, Wikswo JP, Taylor DL. Functional coupling of human microphysiology systems: intestine, liver, kidney proximal tubule, blood-brain barrier and skeletal muscle. Scientific Reports 2017;7:42296 (14 pp.). |
R835736 (2017) R835736C004 (2018) R835738C002 (2017) R835738C005 (2017) |
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| Journal Article | Functional coupling of human microphysiology systems: intestine, liver, kidney proximal tubule, blood-brain barrier and skeletal muscle. | SCIENTIFIC REPORTS | Vernetti L, Gough A, Baetz N, Blutt S, Broughman JR, Brown JA, Foulke-Abel J, Hasan N, In J, Kelly E, Kovbasnjuk O, Repper J, Senutovitch N, Stabb J, Yeung C, Zachos NC, Donowitz M, Estes M, Himmelfarb J, Truskey G, Wikswo JP, Taylor DL | Vernetti L, Gough A, Baetz N, Blutt S, Broughman JR, Brown JA, Foulke-Abel J, Hasan N, In J, Kelly E, Kovbasnjuk O, Repper J, Senutovitch N, Stabb J, Yeung C, Zachos NC, Donowitz M, Estes M, Himmelfarb J, Truskey G, Wikswo JP, Taylor DL. Functional coupling of human microphysiology systems: intestine, liver, kidney proximal tubule, blood-brain barrier and skeletal muscle. Scientific Reports 2017;7:42296 (15 pp.). |
R835736 (2015) R835736 (2016) R835736C004 (2016) R835736C005 (2016) R835738 (2016) R835738C003 (2017) R835738C005 (2017) |
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| Journal Article | Corrigendum: Functional coupling of human microphysiology systems: intestine, liver, kidney proximal tubule, blood-brain barrier and skeletal muscle. | SCIENTIFIC REPORTS | Vernetti L, Gough A, Baetz N, Blutt S, Broughman JR, Brown JA, Foulke-Abel J, Hasan N, In J, Kelly E, Kovbasnjuk O, Repper J, Senutovitch N, Stabb J, Yeung C, Zachos NC, Donowitz M Estes M, Himmelfarb J, Truskey G, Wikswo JP, Taylor DL. | Vernetti L, Gough A, Baetz N, Blutt S, Broughman JR, Brown JA, Foulke-Abel J, Hasan N, In J, Kelly E, Kovbasnjuk O, Repper J, Senutovitch N, Stabb J, Yeung C, Zachos NC, Donowitz M Estes M, Himmelfarb J, Truskey G, Wikswo JP, Taylor DL. Corrigendum: Functional coupling of human microphysiology systems: intestine, liver, kidney proximal tubule, blood-brain barrier and skeletal muscle. Scientific Reports 2017;7:44517. |
R835738 (2016) R835738 (2017) R835738C002 (2016) R835738C002 (2017) R835738C005 (2017) |
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| Journal Article | Occupational exposure limit for silver nanoparticles: considerations on the derivation of a general health-based value. | NANOTOXICOLOGY | Weldon BA, Faustman EM, Oberdorster G, Workman T, Griffith WC, Kneuer C, Yu IJ | Weldon BA, Faustman EM, Oberdorster G, Workman T, Griffith WC, Kneuer C, Yu IJ. Occupational exposure limit for silver nanoparticles: considerations on the derivation of a general health-based value. Nanotoxicology 2016;10(7):945-956. |
R835738 (2015) R835738 (2016) R835738 (2017) R835738C005 (2015) R835738C005 (2016) R835738C005 (2017) |
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| Journal Article | Using primary organotypic mouse midbrain cultures to examine developmental neurotoxicity of silver nanoparticles across two genetic strains. | None | Weldon BA, Park JJ, Hong S, Workman T, Dills R, Lee JH, Griffith WC, Kavanagh TJ, Faustman EM | Weldon BA, Park JJ, Hong S, Workman T, Dills R, Lee JH, Griffith WC, Kavanagh TJ, Faustman EM. Using primary organotypic mouse midbrain cultures to examine developmental neurotoxicity of silver nanoparticles across two genetic strains. Toxicology and Applied Pharmacology 2018:354;215-224 |
R835738 (2017) R835738C004 (2017) R835738C004 (2018) R835738C005 (2017) R835738C005 (2018) |
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| Journal Article | Tissue Distribution of Gold and Silver after Subacute Intravenous Injection of Co-administered Gold and Silver Nanoparticles of similar sizes. | None | Lee JH, Sung JH, Ryu HR, Song KS, Song NW, Park HM, Shin BS, Ahn K, Gulumian M, Faustman EM, Yu IJ | Lee JH, Sung JH, Ryu HR, Song KS, Song NW, Park HM, Shin BS, Ahn K, Gulumian M, Faustman EM, Yu IJ. Tissue Distribution of Gold and Silver after Subacute Intravenous Injection of Co-administered Gold and Silver Nanoparticles of similar sizes. Archives of Toxicology 2018:92(4);1393-1405 |
R835738C004 (2018) R835738C005 (2018) |
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| Journal Article | In vitro to in vivo benchmark dose comparisons to inform risk assessment of quantum dot nanomaterials. | None | Weldon BA, Griffith WC, Workman T, Scoville DK, Kavanagh TJ, Faustman EM | Weldon BA, Griffith WC, Workman T, Scoville DK, Kavanagh TJ, Faustman EM. 2018. In vitro to in vivo benchmark dose comparisons to inform risk assessment of quantum dot nanomaterials. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology 2018;10(4):e1507. |
R835738 (2017) R835738C001 (2018) R835738C004 (2017) R835738C004 (2018) R835738C005 (2017) R835738C005 (2018) |
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| Presentation | Microphysiological systems to identify organ-organ interactions in toxicology: hepatic metabolism enhances nephrotoxicity of aristolochic acid. | None | Chang SY, Weber E, Kelly EJ, Eaton DL | Chang SY, Weber E, Kelly EJ, Eaton DL. Microphysiological systems to identify organ-organ interactions in toxicology: hepatic metabolism enhances nephrotoxicity of aristolochic acid. Presented at the Pacific Northwest Association of Toxicologists Annual Meeting, Woodinville, WA, September 17-18, 2015. |
R835738 (2016) R835738 (2017) R835738C002 (2017) R835738C003 (2015) R835738C005 (2017) |
not available |
| Presentation | Microphysiological Systems (MPS) to identify organ-organ interactions in tToxicology: hepatic metabolism enhances nephrotoxicity of aristolochic acid. | None | Chang SY, Weber E, Neumann T, Kelly EJ, Eaton DL | Chang SY, Weber E, Neumann T, Kelly EJ, Eaton DL. Microphysiological Systems (MPS) to identify organ-organ interactions in tToxicology: hepatic metabolism enhances nephrotoxicity of aristolochic acid. Presented at the Society of Toxicology 55th Annual Meeting and ToxExpo, New Orleans, LA, March 13-17, 2016. |
R835738 (2016) R835738 (2017) R835738C002 (2017) R835738C003 (2015) R835738C005 (2017) |
not available |
| Presentation | New frontiers for linked microphysiological systems: integrated liver-kidney systems on a chip. | None | Eaton D | Eaton D. New frontiers for linked microphysiological systems: integrated liver-kidney systems on a chip. Presented at the 10th World Congress on Alternatives and Animal Use in the Life Sciences (WC10), Seattle, WA, August 20-24, 2017. |
R835738 (2017) R835738C002 (2017) R835738C002 (2018) R835738C003 (2018) R835738C005 (2017) |
not available |
| Presentation | Neurodevelopmental disorders and disease & opportunities for new chemical testing data: understanding new tools from federal chemical testing programs. | None | Faustman EM, Smith MN | Faustman EM, Smith MN. Neurodevelopmental disorders and disease & opportunities for new chemical testing data: understanding new tools from federal chemical testing programs. Presented to the California EPA via webinar, August 14, 2015. |
R834514 (2015) R834514 (Final) R835738 (2016) R835738 (2017) R835738C004 (2015) R835738C005 (2017) |
not available |
| Presentation | Predictive Toxicology Center for Organotypic Cultures and Assessment of AOPs for Engineered Nanomaterials. | None | Faustman EM, Kavanagh TJ, Altemeier W, Kelly E, Griffith WC, Gao X, Van Ness K, Eaton DL | Faustman EM, Kavanagh TJ, Altemeier W, Kelly E, Griffith WC, Gao X, Van Ness K, Eaton DL. Predictive Toxicology Center for Organotypic Cultures and Assessment of AOPs for Engineered Nanomaterials. Poster presented at the Society of Toxicology 54th Annual Meeting and ToxExpo, San Diego, CA, March 22-26, 2015. |
R835738 (2016) R835738 (2017) R835738C002 (2017) R835738C004 (2017) R835738C005 (2017) |
not available |
| Presentation | University of Washington Predictive Toxicology Center update. | None | Faustman EM, Kavanagh TJ | Faustman EM, Kavanagh TJ. University of Washington Predictive Toxicology Center update. Presented at the Society of Toxicology 54th Annual Meeting and ToxExpo, San Diego, CA, March 22-26, 2015. |
R835738 (2016) R835738 (2017) R835738C004 (2017) R835738C005 (2017) |
not available |
| Presentation | Organotypic Cultures and Assessment of AOPs for Engineered Nanomaterials: results from the University of Washington Predictive Toxicology Center (PTC). | None | Faustman EM, Kavanagh TJ, Altemeier W, Kelly E, Griffith WC, Gao X, Van Ness K, Eaton DL | Faustman EM, Kavanagh TJ, Altemeier W, Kelly E, Griffith WC, Gao X, Van Ness K, Eaton DL. Organotypic Cultures and Assessment of AOPs for Engineered Nanomaterials: results from the University of Washington Predictive Toxicology Center (PTC). Poster presented at the Society of Toxicology Contemporary Concepts in Toxicology's FutureTox III: Bridges for Translation Conference, Arlington, VA, November 19-20, 2015. |
R835738 (2016) R835738 (2017) R835738C002 (2017) R835738C004 (2017) R835738C005 (2017) |
not available |
| Presentation | Integrating in vitro studies for risk assessment of quantum dots: applications of dosimetry and benchmark evaluation methods. | None | Faustman EM | Faustman EM. Integrating in vitro studies for risk assessment of quantum dots:applications of dosimetry and benchmark evaluation methods. Presented at the 7th International Symposium on Nanotechnology, Occupational and Environmental Health (NanOEH 2015), University of Witwatersrand, Limpopo Province, South Africa, October 18-22, 2015. |
R835738 (2015) R835738 (2016) R835738 (2017) R835738C004 (2017) R835738C005 (2017) |
not available |
| Presentation | Integrating in vitro studies for risk assessment of quantum dots: applications of dosimetry and benchmark evaluation methods. | None | Faustman EM | Faustman EM. Integrating in vitro studies for risk assessment of quantum dots: applications of dosimetry and benchmark evaluation methods. Presented at the 7th International Symposium on Nanotechnology, Occupational and Environmental Health (NanOEH 2015), Limpopo Province, South Africa, October 19-22, 2015. |
R835738C004 (2017) R835738C005 (2015) R835738C005 (2017) |
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| Presentation | 3D testis culture: challenges and opportunities for informing AOP. | None | Faustman EM | Faustman EM. 3D testis culture: challenges and opportunities for informing AOP. Presented at a seminar in Seattle, WA, August 2016. |
R835738 (2016) R835738 (2017) R835738C004 (2017) R835738C005 (2017) |
not available |
| Presentation | Virtual tissue modeling. | None | Faustman EM | Faustman EM. Virtual tissue modeling. Poster presented at the University of Washington’s Predictive Toxicology Center: Metal and Engineered Nanomaterials Quarterly Update, Seattle WA, August 2016. |
R835738 (2016) R835738 (2017) R835738C005 (2017) |
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| Presentation | Prioritizing toxic chemicals in children’s consumer products. | None | Faustman EM, Smith M | Faustman EM, Smith M. Prioritizing toxic chemicals in children’s consumer products. Presented via the Pediatric Environmental Health Specialty Units (PEHSU) National Classroom Grand Rounds Webinar, December 14, 2016. |
R835738 (2016) R835738 (2017) R835738C004 (2017) R835738C005 (2016) R835738C005 (2017) |
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| Presentation | Virtual tissue modeling. | None | Faustman EM | Faustman EM. Virtual tissue modeling. Poster presented at the University of Washington’s Predictive Toxicology Center: Metal and Engineered Nanomaterials Quarterly Update, Seattle WA, February 2016. |
R835738 (2016) R835738 (2017) R835738C004 (2017) R835738C005 (2017) |
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| Presentation | Framing our birth defects questions with systems biology: learning from our mentors. | None | Faustman EM | Faustman EM. Framing our birth defects questions with systems biology: learning from our mentors. Presented at the 56th Annual Teratology Society Meeting, San Antonio, TX, June 26, 2016 (Josef Warkany lecture). |
R835738 (2016) R835738 (2017) R835738C004 (2017) R835738C005 (2017) |
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| Presentation | Exposomes for children's studies: importance of life stage considerations. | None | Faustman EM | Faustman EM. Exposomes for children's studies: importance of life stage considerations. Presented at the NIEHS/EPA Children’s Centers Webinar Series: Exposome, Research Triangle Park, NC, May 11, 2016. |
R835738 (2016) R835738 (2017) R835738C004 (2017) R835738C005 (2017) |
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| Presentation | Children matter: using a lifecourse approach to understanding safety assessment needs for children. | None | Faustman EM | Faustman EM. Children matter: using a lifecourse approach to understanding safety assessment needs for children. Presented via webinar at the Society of Toxicology (SOT)/U.S. Food and Drug Administration (FDA) Colloquia on Emerging Toxicological Science: Challeges in Food and Ingredients Safety, College Park, MD, May 20, 2016. |
R835738 (2016) R835738 (2017) R835738C005 (2017) |
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| Presentation | Virtual tissue modeling. | None | Faustman EM | Faustman EM. Virtual tissue modeling. Poster presented at the University of Washington’s Predictive Toxicology Center: Metal and Engineered Nanomaterials Quarterly Update, Seattle WA, May 2016. |
R835738 (2016) R835738 (2017) R835738C004 (2017) R835738C005 (2017) |
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| Presentation | Systems biology methods for translation of scientific findings across model platforms: identifying normal development versus chemical signals in complex systems. | None | Faustman EM | Faustman EM. Systems biology methods for translation of scientific findings across model platforms: identifying normal development versus chemical signals in complex systems. Presented at the 10th World Congress on Alternatives and Animal Use in the Life Sciences (WC10), Seattle, WA, August 20-24, 2017. |
R835738 (2017) R835738C001 (2018) R835738C002 (2017) R835738C004 (2017) R835738C004 (2018) R835738C005 (2017) |
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| Presentation | Integrating systems biology and public health to implement 3Rs–what have we learned and what do we need to do? Presented at the Institutional Animal Care and Use Committee (IACUC) Conference, New Orleans, LA, March 19-20, 2017 (keynote speaker). | None | Faustman EM | Faustman EM. Integrating systems biology and public health to implement 3Rs–what have we learned and what do we need to do? Presented at the Institutional Animal Care and Use Committee (IACUC) Conference, New Orleans, LA, March 19-20, 2017 (keynote speaker). |
R835738 (2017) R835738C004 (2017) R835738C005 (2017) |
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| Presentation | Incorporating in vitro reproductive and developmental assays into regulatory risk assessment. | None | Fitzpatrick SC | Fitzpatrick SC. Incorporating in vitro reproductive and developmental assays into regulatory risk assessment. Presented at the Society of Toxicology 56th Annual Meeting and ToxExpo, Baltimore, MD, March 12-16, 2017. |
R835738 (2016) R835738 (2017) R835738C004 (2017) R835738C005 (2017) |
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| Presentation | Comparing engineered nanomaterial toxicity across species, partcles and cell types: the benefit of 3D over 2D in vitro systems, and the role of genetics in predicting ENM adverse outcome. | None | Kavanagh T | Kavanagh T. Comparing engineered nanomaterial toxicity across species, partcles and cell types: the benefit of 3D over 2D in vitro systems, and the role of genetics in predicting ENM adverse outcome. Presented at a seminar, Seattle, WA, August 2016. |
R835738 (2016) R835738 (2017) R835738C005 (2016) R835738C005 (2017) |
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| Presentation | Educational tools for designing safer chemicals and predicting toxicity. | None | Kavanagh T | Kavanagh T. Educational tools for designing safer chemicals and predicting toxicity. Presented at the 10th World Congress on Alternatives and Animal Use in the Life Sciences (WC10), Seattle, WA, August 20-24, 2017. |
R835738 (2017) R835738C002 (2018) R835738C003 (2018) R835738C005 (2017) |
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| Presentation | Experiences with collaborative cross for assessing gene X environment interactions for engineered nanomaterials:can we capture human variability in vitro-lessons from the Predictive Toxicology Center. | None | Kavanagh T | Kavanagh T. Experiences with collaborative cross for assessing gene X environment interactions for engineered nanomaterials: can we capture human variability in vitro-lessons from the Predictive Toxicology Center. Presented at the 10th World Congress on Alternatives and Animal Use in the Life Sciences (WC10), Seattle, WA, August 20-24, 2017. |
R835738 (2017) R835738C002 (2017) R835738C003 (2018) R835738C005 (2017) |
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| Presentation | The 3 R’s of toxicology and the role of microphysiological systems. | None | Kelly EJ | Kelly EJ. The 3 R’s of toxicology and the role of microphysiological systems. Presented at the Institute for Stem Cell and Regenerative Medicine (ISCRM) Seminar Series, Seattle, WA, December 13, 2016. |
R835738 (2016) R835738 (2017) R835738C002 (2016) R835738C002 (2017) R835738C005 (2017) |
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| Presentation | Organs on chips and reducing the need for animal studies. | None | Kelly EJ | Kelly EJ. Organs on chips and reducing the need for animal studies. Presented at the Pacific Northwest Association of Toxicologists (PANWAT) Annual Meeting, Oregon State University, Corvallis, OR, September 29-30, 2016. |
R835738 (2016) R835738 (2017) R835738C002 (2016) R835738C002 (2017) R835738C005 (2017) |
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| Presentation | Emergent technologies for evaluating drug and xenobiotic disposition. | None | Kelly EJ | Kelly EJ. Emergent technologies for evaluating drug and xenobiotic disposition. Presented at the 21st North American ISSX Meeting of the International Society for the Study of Xenobiotics (ISSX), Providence, RI, September 24-28, 2017 (symposium co-chair). |
R835738 (2017) R835738C001 (2018) R835738C002 (2017) R835738C002 (2018) R835738C005 (2017) |
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| Presentation | Bioengineered ex vivo models of human organs for predictive toxicity testing. | None | Kelly E | Kelly E. Bioengineered ex vivo models of human organs for predictive toxicity testing. Presented at the New England Drug Metabolism Discussion Group Meeting, Walkersville, MD, December 6, 2017 |
R835738 (2017) R835738C002 (2017) R835738C002 (2018) R835738C003 (2018) R835738C005 (2017) |
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| Presentation | Microphysiological system models and the Lautenberg Chemical Safety for the 21st Century Act. | None | Klieforth B, Shaffer RM, mith M, Faustman EM | Klieforth B, Shaffer RM, Smith M, Faustman EM. Microphysiological system models and the Lautenberg Chemical Safety for the 21st Century Act. Presented at the 10th World Congress on Alternatives and Animal Use in the Life Sciences (WC10), Seattle, WA, August 20-24, 2017. |
R835738 (2017) R835738C001 (2018) R835738C002 (2017) R835738C002 (2018) R835738C004 (2017) R835738C004 (2018) R835738C005 (2017) |
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| Presentation | Silver nanoparticles dosimetry-response comparison in in vitro primary organotypic C57BL/6 and A/J mouse midbrain micromass cultures at various developmental stages. | None | Park JJ, Weldon BA, Hong S, Workman T, Dills R, Griffith WC, Kavanagh TJ, Faustman EM | Park JJ, Weldon BA, Hong S, Workman T, Dills R, Griffith WC, Kavanagh TJ, Faustman EM. Silver nanoparticles dosimetry-response comparison in in vitro primary organotypic C57BL/6 and A/J mouse midbrain micromass cultures at various developmental stages. Presented at the 10th World Congress on Alternatives and Animal Use in the Life Sciences (WC10), Seattle, WA, August 20-24, 2017. |
R835738 (2017) R835738C005 (2017) |
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| Presentation | Practical promotion of the 3Rs in animal models of lung disease. | None | Pekow C, Altemeier WA | Pekow C, Altemeier WA. Practical promotion of the 3Rs in animal models of lung disease. Presented at the 10th World Congress on Alternatives and Animal Use in the Life Sciences (WC10), Seattle, WA, August 20-24, 2017. |
R835738 (2017) R835738C001 (2017) R835738C001 (2018) R835738C005 (2017) |
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| Presentation | Lifestage-specific organotypic modeling platform for adverse outcome pathways of male reproductive and developmental processes. | None | Shaffer RM, Welder CS, Ryu C, Yi HS, Park SY, Hong S, White CC, Workman T, Griffith WC, Faustman EM | Shaffer RM, Welder CS, Ryu C, Yi HS, Park SY, Hong S, White CC, Workman T, Griffith WC, Faustman EM. Lifestage-specific organotypic modeling platform for adverse outcome pathways of male reproductive and developmental processes. Poster presented at the 10th World Congress on Alternatives and Animal Use in the Life Sciences (WC10), Seattle, WA, August 20-24, 2017. |
R835738 (2017) R835738C004 (2017) R835738C004 (2018) R835738C005 (2017) |
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| Presentation | Lifestage-specific modeling platform for adverse outcome pathways of male reproductive and developmental processes. | None | Shaffer R, Wilder CS, Ryu C, Yi HS, Park SY, Hong S, White CC, Workman T, Griffith WC, Faustman EM | Shaffer R, Wilder CS, Ryu C, Yi HS, Park SY, Hong S, White CC, Workman T, Griffith WC, Faustman EM. Lifestage-specific modeling platform for adverse outcome pathways of male reproductive and developmental processes. Poster presented at the Pacific Northwest Association of Toxicologists (PANWAT) Annual Meeting, Oregon State University, Corvallis, OR, September 29-30, 2016. |
R835738 (2016) R835738 (2017) R835738C002 (2017) R835738C004 (2017) R835738C005 (2017) |
not available |
| Presentation | Developing a toxicological framework for the interpretation of the Children’s Safe Product Act data. | None | Smith MN, Faustman EM, Grice J | Smith MN, Faustman EM, Grice J. Developing a toxicological framework for the interpretation of the Children’s Safe Product Act data. Presented at the 7th Annual Northwest Environmental Health Conference, Portland, OR, April 17, 2015. |
R834514 (Final) R835738 (2015) R835738C005 (2015) |
not available |
| Presentation | Using a toxicological framework for chemical prioritization from the Children’s Safe Product Act | None | Smith MN, Grice J, Faustman EM | Smith MN, Grice J, Faustman EM. Using a toxicological framework for chemical prioritization from the Children’s Safe Product Act. Presented at the Society for Risk Analysis (SRA) Annual Meeting, Arlington, VA, December 7, 2015. |
R835738 (2015) R835738 (2016) R835738 (2017) R835738C005 (2015) |
not available |
| Presentation | Developing a toxicological framework for the prioritization of the Children’s Safe Product Act data. | None | Smith MN | Smith MN. Developing a toxicological framework for the prioritization of the Children’s Safe Product Act data. Presented via the Interstate Chemical Clearinghouse (IC2) Meeting, May 18, 2016. |
R835738 (2016) R835738 (2017) R835738C005 (2016) |
not available |
| Presentation | A framework for the derivation of a health-based occupation exposure limit for silver nanoparticles. | None | Weldon BA, Faustman EM, Oberdorster G, Workman T, Griffith WC, Kneuer C, Yu IJ | Weldon BA, Faustman EM, Oberdorster G, Workman T, Griffith WC, Kneuer C, Yu IJ. A framework for the derivation of a health-based occupation exposure limit for silver nanoparticles. Poster presented at the Pacific Northwest Association of Toxicologists (PANWAT) Annual Meeting, Woodinville, WA, September 17-18, 2015. |
R835738 (2015) R835738 (2016) R835738 (2017) R835738C005 (2015) R835738C005 (2017) |
not available |
| Presentation | A framework for the derivation of a health-based occupation exposure limit for silver nanoparticles. | None | Weldon BA, Faustman EM, Oberdorster G, Workman T, Griffith WC, Kneuer C, Yu IJ | Weldon BA, Faustman EM, Oberdorster G, Workman T, Griffith WC, Kneuer C, Yu IJ. A framework for the derivation of a health-based occupation exposure limit for silver nanoparticles. Poster presented at the Society of Toxicology 55th Annual Meeting and ToxExpo, New Orleans, LA, March 13-17, 2016. |
R835738 (2015) R835738 (2016) R835738 (2017) R835738C005 (2015) R835738C005 (2017) |
not available |
| Presentation | Organotypic modeling platform for adverse outcome pathways of male reproductive and developmental processes. | None | Wilder CS, Wegner SH | Wilder CS, Wegner SH, Organotypic modeling platform for adverse outcome pathways of male reproductive and developmental processes. Presented webinar at Virtual Tissues Meeting, Research Triangle Park, NC, May 2016. |
R835738 (2016) R835738 (2017) R835738C004 (2017) R835738C005 (2017) |
not available |
| Presentation | , Altemeier W, Kelly E, Griffith WC, Gao X, Van Ness K, Eaton DL. | None | Faustman EM, Kavanagh TJ | Faustman EM, Kavanagh TJ., Altemeier W, Kelly E, Griffith WC, Gao X, Van Ness K, Eaton DL. Organotypic Cultures and Assessment of AOPs for Engineered Nanomaterials; Results from the University of Washington Predictive Toxicology Center (PTC). Poster presented at the Society of Toxicology Contemporary Concepts in Toxicology's FutureTox III: Bridges for Translation Conference, Arlington, VA, November19-20, 2015. |
R835738 (2017) R835738C004 (2017) R835738C005 (2017) |
not available |
| Symposium | . | None | Ed Kelly, Symposium Co-Chair, 2017 North American Annual ISSX Annual Meeting, Providence, RI, Emergent Technologies for Evaluating Drug Xenobiotic Disposition | Kelly E. Symposium Co-Chair of the 21st North American ISSX Meeting, Emergent Technologies for Evaluating Drug and Xenobiotic Disposition, Providence, RI, September 24-28, 2017. |
R835738 (2017) R835738C001 (2018) R835738C002 (2017) R835738C005 (2017) R835738C005 (2018) |
not available |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.