Grantee Research Project Results
Associated Project Details for RFA: Organotypic Culture Models for Predictive Toxicology Center (2013)| R835736 | Vanderbilt - Pittsburgh Resource for Organotypic Models for Predictive Toxicology | Centers | December 1, 2014 through November 30, 2018 (Extended to November 30, 2019) |
| R835736C001 | Mammosphere Bioreactor For Life-Stage Specific Toxicology | Centers | December 1, 2014 through November 30, 2018 (Extended to November 30, 2019) |
| R835736C002 | Organotypic Culture Model to Analyze DevelopmentalLimbMalformationsResulting from Toxicant/Teratogen Exposure | Centers | December 1, 2014 through November 30, 2018 (Extended to November 30, 2019) |
| R835736C003 | Validating a fetal membrane on a chip model for characterizing reproductive toxicant exposure risks | Centers | December 1, 2014 through November 30, 2018 (Extended to November 30, 2019) |
| R835736C004 | Organotypic Liver Model for Predictive Human Toxicology and Metabolism | Centers | December 1, 2014 through November 30, 2018 (Extended to November 30, 2019) |
| R835736C005 | Systems Engineering & Analysis for Organotypic Culture Models | Centers | December 1, 2014 through November 30, 2018 (Extended to November 30, 2019) |
| R835737 | Human Models for Analysis of Pathways (H MAPs) Center | Centers | December 1, 2014 through November 30, 2018 (Extended to November 30, 2019) |
| R835737C001 | Liver MAPs | Centers | December 1, 2014 through November 30, 2018 (Extended to November 30, 2019) |
| R835737C002 | Brain MAPs | Centers | December 1, 2014 through November 30, 2018 (Extended to November 30, 2019) |
| R835737C003 | Cancer MAPs: A 3D Organotypic Microfluidic Culture System to Identify Chemicals that Impact Progression and Development of Breast Cancer | Centers | December 1, 2014 through November 30, 2018 (Extended to November 30, 2019) |
| R835737C004 | Vascular MAPs: Vascular and Neurovascular Tissue Models | Centers | December 1, 2014 through November 30, 2018 (Extended to November 30, 2019) |
| R835737C005 | Pathway Analysis Core | Centers | December 1, 2014 through November 30, 2018 (Extended to November 30, 2019) |
| R835738 | Predictive Toxicology Center for Organotypic Cultures and Assessment ofAOPs for Engineered Nanomaterials | Centers | December 1, 2014 through November 30, 2019 (Extended to November 30, 2020) |
| R835738C001 | Airway Epithelium Organotypic Culture as a Platform forAdverseOutcomesPathway Assessment of Engineered Nanomaterials | Centers | December 1, 2014 through November 30, 2018 (Extended to November 30, 2020) |
| R835738C002 | Organotypic Model of Human Kidney as a Platform for Adverse Outcomes Pathway Assessment of Engineered Nanomaterials | Centers | December 1, 2014 through November 30, 2018 (Extended to November 30, 2019) |
| R835738C003 | Organotypic Models of Mammalian Liver as a Platform for Adverse Outcomes Pathway Assessment of Engineered Nanomaterials | Centers | December 1, 2014 through November 30, 2018 (Extended to November 30, 2019) |
| R835738C004 | Organotypic Model of Testis as a Platform for Adverse Outcomes Pathway Assessment of Engineered Nanomaterials | Centers | December 1, 2014 through November 30, 2018 (Extended to November 30, 2019) |
| R835738C005 | Integrating Liver, Kidney and Testis Nanomaterial Toxicity using the Adverse Outcome Pathway Approach | Centers | December 1, 2014 through November 30, 2018 (Extended to November 30, 2019) |
| R835802 | Cardiotoxicity Adverse Outcome Pathway: Organotypic Culture Model and in vitro-to-in vivo Extrapolation for High-throughput Hazard, Dose-response and Variability Assessments | Centers | June 1, 2015 through May 31, 2019 (Extended to May 31, 2022) |
| R835802C001 | High-throughput Hazard,Dose-responseandPopulationVariabilityAssessmentofCardiotoxicity in aHumanInducedPluripotentStem Cell(iPSC)-derivedinvitro Culture Model | Centers | June 1, 2015 through May 31, 2019 (Extended to May 31, 2021) |
| R835802C002 | Linking in vitro-to-in vivoToxicity Testing Using Genetically-matchedOrganoids and Mice from a Novel Genetic Reference Population | Centers | June 1, 2015 through May 31, 2019 (Extended to May 31, 2020) |
| R835802C003 | A Pipeline for in vitro-to-in vivo Extrapolation, Population Modeling, & Prioritization | Centers | June 1, 2015 through May 31, 2019 (Extended to May 31, 2020) |