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Records 1 to
25
of 129 records from author Brian Chorley
2024
Ledbetter, V., J. Liu, Jessica Hanson, B. Chorley, AND Jon Corton. A Gene Expression Biomarker Identifies Activation of XBP-1 by Chemical Inducers of the Unfolded Protein Response (UPR) in a Gene Expression Compendium. SOT, Salt Lake City, UT, March 11 - 14, 2024. https://doi.org/10.23645/epacomptox.25534159
O'Neill, J., J. Harrill, AND B. Chorley. Functional Genomic-Based Characterization of the Retinoic Acid Pathway in U-2 OS Cells Using CRISPRa-dCas9. 2024 SOT Annual Meeting, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25533442
Dasgupta, S., T. Sharapova, P. Mahalingaiah, B. Chorley, A. Abokifa, T. Tsuji, A. dos Santos, R. Chari, A. Ebrahimi, D. Dalmas, S. Pettit, B. Bawa, E. Vaughan, T. van Vleet, C. Mitchell, AND P. Yuen. Urinary MicroRNA Biomarkers of Drug-induced Kidney Injury (DIKI) Demonstrate Differences in Sensitivity within Exosomal Fraction Compared to Whole Urine. SOT Annual meeting, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25565628
2023
Park, S., D. Gallegos, S. Jeffay, E. Hunter, AND B. Chorley. All-Trans Retinoic Acid-Mediated Transcriptomic Signatures in Human Pluripotent Stem Cells at Single-Cell Resolution. Environmental Mutagenesis and Genomics Society (EMGS) 54th Annual Meeting, Chicago, IL, September 09 - 13, 2023. https://doi.org/10.23645/epacomptox.24128769
Nelson, G., G. Carswell, C. Swartz, L. Recio, C. Yauk, AND B. Chorley. Early microRNA responses in rodent liver mediated by furan exposure establish dose thresholds for later adverse outcomes. TOXICOLOGY LETTERS. Elsevier Science Ltd, New York, NY, 384:105-114, (2023). https://doi.org/10.1016/j.toxlet.2023.07.015
Chorley, B. Extracellular microRNA as Biomarkers of Environmental Chemical Health Hazard Identification. Society of Toxicology 62nd Annual Meeting and ToxExpo, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.22755002
Nelson, G., J. Harrill, AND B. Chorley. Extracellular microRNAs are sensitive biomarkers of chemical-mediated toxicity and other mechanisms of action. Society of Toxicology 62nd Annual Meeting and ToxExpo 2023, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.22714315
Tucker, N., G. Nelson, J. Harrill, AND B. Chorley. High Content Imaging Assessment of Chemical Hepatotoxicity and Differential Impact of Pre-Existing Hepatic Steatosis. Society of Toxicology 62nd Annual Meeting and ToxExpo 2023, Nashville, NC, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.24917250
Chorley, B. Life as Researcher at the US EPA: A little about me, the Agency, and some data... KUMC Industrial Toxicology Lecture Series, Kansas City Virtual/Zoom, KS, February 22, 2023. https://doi.org/10.23645/epacomptox.22762412
Ge, Y., M. Bruno, M. Nash, AND B. Chorley. Vinyl Chloride Enhances High Fat Diet-Induced Proteome Alterations in the Mouse Pancreas Related to Metabolic Dysfunction: Implications for Individual Susceptibility. Society of Environmental Toxicology and Chemistry SETAC Europe 33rd Annual Meeting, Dublin, N/A, IRELAND, April 30 - May 04, 2023. https://doi.org/10.23645/epacomptox.22798526
Ge, Y., M. Bruno, M. Nash, N. Haykal-Coates, B. Chorley, M. Cave, AND J. Beier. Vinyl chloride altered pancreas proteome and pathways associated with metabolism and predisposed mouse to enhanced metabolic stress. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 193(1):103-114, (2023). https://doi.org/10.1093/toxsci/kfad024
2022
Cave, M., C. Pinkston, S. Rai, B. Wahlang, M. Pavuk, K. Head, G. Carswell, G. Nelson, C. Klinge, D. Bell, L. Birnbaum, AND B. Chorley. Circulating MicroRNAs, Polychlorinated Biphenyls, and Environmental Liver Disease in the Anniston Community Health Survey. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 130(1):017003, (2022). https://doi.org/10.1289/EHP9467
Miller, C., J. Dye, L. Strader, G. Nelson, M. Schladweiler, H. Nguyen, G. Carswell, G. Palmer, Matthew Gilmour, B. Chorley, AND G. Klinefelter. Exposure to eucalyptus smoke during sperm maturation alters motility and non-coding RNAs in caudal sperm. International Particulate Toxicology Conference, Santa Fe, NM, August 28 - 31, 2022.
Chorley, B. Genetic and epigenetic alterations associated with latent liver carcinogenesis due to early-life dichloroacetic acid exposure in mice. Society of Toxicology, San Diego, CA, March 27 - 31, 2022. https://doi.org/10.23645/epacomptox.19412348
Marable, C., C. Frank, R. Seim, S. Hester, Matt Henderson, B. Chorley, AND T. Shafer. Integrated Omic Analyses Identify Pathways and Transcriptomic Regulators Associated with Chemical Alterations of in vitro Neural Network Formation. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 186(1):118-133, (2022). https://doi.org/10.1093/toxsci/kfab151
Nelson, G. AND B. Chorley. Micro RNAs as Non-Invasive Biomarkers of Toxicity and Chemical Hazard. Chapter 2, Saura C. Sahu (ed.), Genomic and Epigenomic Biomarkers of Toxicology and Disease: Clinical and Therapeutic Actions. John Wiley and Sons, LTD, , Uk, , 7-35, (2022). https://doi.org/10.1002/9781119807704.ch2
Cave, M., C. Pinkston, S. Rai, B. Wahlang, G. Carswell, M. Pavuk, L. Birnbaum, AND B. Chorley. MicroRNA Liver Toxicity Biomarkers Associated with Dioxin-Like Molecule Exposures in ACHS-II. Society of Toxicology 61st Annual Meeting and ToxExpo 2022, San Diego, CA, March 27 - 31, 2022. https://doi.org/10.23645/epacomptox.20344038
Chorley, B. MicroRNA biomarker development for chemical screening and hazard identification. NCSU Toxicology Seminar Series, Raleigh, NC, October 18, 2022. https://doi.org/10.23645/epacomptox.21371343
Cave, M., C. Pinkston, S. Rai, B. Wahlang, K. Head, G. Carswell, L. Birnbaum, AND B. Chorley. Persistent organic pollutant exposures are associated with liver toxicity and decreased albumin in a highly exposed human cohort. American Association for the Study of Liver Disease (AASLD) The Liver Meeting, Washington, DC, November 04 - 08, 2022. https://doi.org/10.23645/epacomptox.21717740
Gallegos, D., S. Jeffay, G. Carswell, B. Chorley, AND S. Hunter. Single-cell RNA Sequencing of Human Embryonic Stem Cells Reveals Immediate and Deferred Transcriptomic Responses to ATRA Toxicity Across Cell Sub-populations. Society of Toxicology, San Diego, CA, March 27 - 31, 2022. https://doi.org/10.23645/epacomptox.19422107
Chorley, B., T. Sharapova, T. Tsuji, P. Yuen, P. Mahalingaiah, C. Mitchell, AND S. Pettit. Urinary MicroRNA Biomarkers of Nephrotoxicity Demonstrate Reduced Variability and Directionality in Exosomal Compared to Whole Fractions. 13th International Conference on Environmental Mutagens, Ottawa, CANADA, August 27 - September 01, 2022. https://doi.org/10.23645/epacomptox.20384181
2021
Cave, M., C. Pinkston, S. Rai, M. Pavuk, K. Head, B. Wahlang, AND B. Chorley. Circulating microRNAs are associated with PCB exposures and liver disease in the Anniston Community Health Survey. Society of Toxicology 2021 Virtual Annual Meeting, NA, Virtual, March 12 - 26, 2021. https://doi.org/10.23645/epacomptox.14470704
Chorley, B. Epigenetics in Risk Assessment: Clarity or Confusion? Environmental Mutagenesis and Genomics Society (EMGS) Virtual Annual meeting, Research Triangle Park, NC, September 22 - 25, 2021. https://doi.org/10.23645/epacomptox.16688776
Tucker, N., G. Nelson, J. Harrill, AND B. Chorley. High-throughput Assessment of Increased Chemical Toxicity Due to Hepatic Steatosis. Environmental Mutagenesis and Genomics Society meeting September 2021 (EMGS) Virtual Annual meeting, Research Triangle Park, NC, September 22 - 25, 2021. https://doi.org/10.23645/epacomptox.17318912
Tucker, N., G. Nelson, J. Harrill, AND B. Chorley. High-throughput Assessment of Increased Chemical Toxicity Due to Hepatic Steatosis (SOT 2021). Society of Toxicology 2021 Annual meeting, NA, Virtual, March 12 - 26, 2021. https://doi.org/10.23645/epacomptox.18127739