Science Inventory

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Gallegos, D., C. Marable, B. Chorley, K. Wallace, T. Freudenrich, AND T. Shafer. Integration of Genomic Data Streams in an In Vitro Network Development Model. Society of Toxicology 2021 Virtual Annual Meeting, Virtual, North Carolina, March 12 - 26, 2021. https://doi.org/10.23645/epacomptox.14466096

Chorley, B., E. Atabakhsh, G. Doran, J. Gautier, H. Ellinger-Ziegelbauer, D. Jackson, T. Sharapova, P. Yuen, R. Church, P. Couttet, R. Froetschl, J. McDuffie, V. Martine, P. Pande, L. Peel, C. Rafferty, F. Simutis, AND A. Harrill. Methodological considerations for measuring biofluid-based microRNA biomarkers. CRITICAL REVIEWS IN TOXICOLOGY. Taylor & Francis Group, London, Uk, 51(3):264-282, (2021). https://doi.org/10.1080/10408444.2021.1907530

Cave, M., C. Pinkston, S. Rai, B. Wahlang, M. Pavuk, K. Head, L. Jophlin, L. Birnbaum, AND B. Chorley. MicroRNA Biomarkers of Liver and Metabolic Toxicities Associated with Environmental Exposures to Dioxin-like Pollutants. AASLD The Liver Meeting, Anaheim, CA, November 12 - 15, 2021. https://doi.org/10.23645/epacomptox.24881571

Pinkston, C., M. Cave, B. Chorley, M. Pavuk, L. Birnbaum, AND S. Rai. Normalization Methods and Statistical Inference to Identify Differentially Expressed MicroRNAs with an Application to a Residential Cohort Exposed to Environmental Toxins and Pollutants. Women in Statistics and Data Science Conference, Raleigh, NC, October 06 - 08, 2021. https://doi.org/10.23645/epacomptox.17430017

Harrill, J., M. Viant, C. Yauk, M. Sachana, T. Gant, S. Auerbach, R. Beger, M. Bouhifd, J. O'Brien, L. Burgoon, F. Caiment, D. Carpi, T. Chen, B. Chorley, J. Colbourne, R. Corvi, L. Debrauwer, C. O'Donovan, T. Ebbels, D. Ekman, F. Faulhammer, L. Gribaldo, G. Hilton, S. Jones, A. Kende, T. Lawson, S. Leite, P. Leonards, M. Luijten, A. Martin, L. Moussa, S. Rudaz, O. Schmitz, T. Sobanski, V. Strauss, M. Vaccari, V. Vijay, R. Weber, A. Williams, A. Williams, R. Thomas, AND M. Whelan. Progress Towards an OECD Reporting Framework for Transcriptomics and Metabolomics in Regulatory Toxicology. REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, 125:105020, (2021). https://doi.org/10.1016/j.yrtph.2021.105020

Nelson, G., G. Carswell, C. Swartz, L. Recio, AND B. Chorley. Quantitative Dose-Response of Liver MicroRNA After Furan Exposure in Rodent Liver, Blood, and Cell Culture. Society of Toxicology 2021 Virtual Annual meeting, NA, Virtual, March 12 - 26, 2021. https://doi.org/10.23645/epacomptox.18130661

Chorley, B. AND O. Lozoya. The methodological road toward single cell high-throughput transcriptomics (scHTTr). Society of Toxicology 2021 Virtual Annual Meeting, Virtual, NC, March 12 - 26, 2021. https://doi.org/10.23645/epacomptox.16799461

Chorley, B., H. Ellinger-Ziegelbauer, M. Tackett, F. Simutis, A. Harrill, J. McDuffie, E. Atabakhsh, R. Nassirpour, L. Whiteley, J. Léonard, G. Carswell, E. Harpur, C. Chen, AND J. Gautier. Urinary miRNA Biomarkers of Drug-Induced Kidney Injury and Their Site Specificity Within the Nephron. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 180(1):1-16, (2021). https://doi.org/10.1093/toxsci/kfaa181

Chorley, B. Biomarkers of Effect Use in Environmental Health Research and Decision Making: MicroRNAs as an Example. National Academy of Sciences Workshop on Predicting Human Health Effects from Environmental Exposures: Applying Translatable and Accessible Biomarkers of Effect, Research Triangle Park, NC, August 12 - 13, 2020. https://doi.org/10.23645/epacomptox.12869471

Chorley, B., G. Carswell, G. Nelson, V. Bhat, AND C. Wood. Early MicroRNA Indicators of PPARα Pathway Activation in the Liver. Toxicology Reports. Elsevier B.V., Amsterdam, Netherlands, 7:805-815, (2020). https://doi.org/10.1016/j.toxrep.2020.06.006

Malloy, M., G. Carswell, B. Bennet, P. Bushel, L. Wehmas, S. Hester, AND B. Chorley. Establishing methods to assess epigenetic signatures in archived study tissues. 2020 SOT Annual Meeting, Research Triangle Park, NC, March 15 - 19, 2020. https://doi.org/10.23645/epacomptox.14340239

Tong, H., S. Snow, H. Chen, Mette C. Schladweiler, G. Carswell, B. Chorley, AND U. Kodavanti. Fish Oil and Olive Oil-Enriched Diets Alleviate Acute Ozone-induced Cardiovascular Effects in Rats. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, 409:115296, (2020). https://doi.org/10.1016/j.taap.2020.115296

Tucker, N., G. Nelson, J. Harrill, AND B. Chorley. Hepatic Steatosis Shifts Phase I Metabolism & Alters In Vitro Toxicant Susceptibility. Environmental Mutagenesis & Genomics Society Virtual Annual Meeting, NA, NC, September 12 - 16, 2020. https://doi.org/10.23645/epacomptox.13157924

Tucker, N., G. Nelson, J. Harrill, AND B. Chorley. Hepatic Steatosis Shifts Phase I Metabolism & Alters In Vitro Toxicant Susceptibility (SOT). SOT 2020 Annual meeting, Sacramento, CA, March 15 - 19, 2020. https://doi.org/10.23645/epacomptox.14341688

Ge, Y., M. Bruno, B. Chorley, M. Cave, AND J. Biere. Investigating Steatosis Susceptibility in Pancreas Tissue of Mouse in Response to Vinyl Chloride Exposure. 2020 SOT, Anaheim, California, March 15 - 19, 2020. https://doi.org/10.23645/epacomptox.12685769

Rooney, J., B. Chorley, S. Hiemstra, S. Wink, X. Wang, D. Bell, B. van de Water, AND Jon Corton. Mining a human transcriptome database for chemical modulators of Nrf2 (PLOS ONE). PLOS ONE . Public Library of Science, San Francisco, CA, 15(9):e0239367, (2020). https://doi.org/10.1371/journal.pone.0239367

Miller, C., J. Dye, A. Henriquez, E. Stewart, K. Lavrich, G. Carswell, H. Ren, D. Freeborn, S. Snow, Mette C. Schladweiler, J. Richards, Prasada Rao Kodavanti, A. Fisher, B. Chorley, AND U. Kodavanti. Ozone-induced fetal growth restriction in rats is associated with sexually dimorphic placental and fetal metabolic adaptation. Molecular Metabolism. Elsevier B.V., Amsterdam, Netherlands, 42:101094, (2020). https://doi.org/10.1016/j.molmet.2020.101094

Cave, M., C. Pinkston, S. Rai, G. Carswell, G. Nelson, K. Head, B. Wahlang, Y. Saad, M. Pavuk, AND B. Chorley. Serum microRNA Profiling Yields Mechanistic Insight into a Residential Cohort with Environmental Liver Disease. American Association for the Study of Liver Diseases (AASLD) The Liver Meeting, NA, Virtual, November 13 - 16, 2020. https://doi.org/10.23645/epacomptox.13266578

Liu, J., J. Cui, S. Gunewardena, C. Klaasseen, B. Chorley, AND Jon Corton. Transplacental arsenic exposure produced 5-methylcytosine methylation changes and aberrant microRNA expressions in livers of male fetal mice. TOXICOLOGY. Elsevier Science Ltd, New York, NY, 435:152409, (2020). https://doi.org/10.1016/j.tox.2020.152409

Chorley, B. miRror, miRror: the biofluid-based biomarker reflective of biological effect. October meeting for NIH Circulating Nucleic Acids/Liquid Biopsy (CNA/LB) Scientific Interest Group, Virtual meeting, NC, October 13, 2020. https://doi.org/10.23645/epacomptox.13376000

Franklin, J., B. Chorley, V. Moser, W. Oshiro, T. Beasley, Kathy Mcdaniel, AND D. Herr. A Lack of Changes in the Transcriptomic Response in the Hippocampus or Amygdala After Developmental Exposure to Mild Variable Stress. Society of Toxicology Annual Meeting, Baltimore, Maryland, March 10 - 14, 2019.

Rooney, J., B. Chorley, AND C. Corton. A gene expression biomarker identifies factors that modulate sterol regulatory element binding protein. Computational Toxicology. Elsevier B.V., Amsterdam, Netherlands, 10:63-77, (2019). https://doi.org/10.1016/j.comtox.2018.12.007

Franklin, J., B. Chorley, V. Moser, W. Oshiro, T. Beasley, K. McDaniel, AND D. Herr. Adult Offspring Performance in Trace Fear Conditioning after Concurrent Developmental Exposure to Variable Stress and Manganese. Developmental Neurotoxicology Society Meeting, San Diego, CA, June 23 - 26, 2019.

Chorley, B. AND S. Hester. Editorial overview: “Toxico-omic” Distillation for Regulatory Application in Human Health. Current Opinion in Toxicology. Elsevier BV, AMSTERDAM, Netherlands, 18:iii-vi, (2019). https://doi.org/10.1016/j.cotox.2019.09.007

Wehmas, L., C. Wood, B. Chorley, C. Yauk, G. Nelson, AND S. Hester. Enhanced Quality Metrics for Assessing RNA Derived From Archival Formalin-Fixed Paraffin-Embedded Tissue Samples. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 170(2):357-373, (2019). https://doi.org/10.1093/toxsci/kfz113