Selected Publications for Center:

The Center for Study of Neurodevelopment and Improving Children's Health

Grant Number R835437

Book Chapter (5)
Journal Article (33)
Reference Type Reference Title Journal Author Citation Progress Report Year Document Sources
Book Chapter Developmental toxicology and children’s environmental health. None Levin ED Levin ED. Developmental toxicology and children’s environmental health. In: Landrigan PJ, Etzel RA, eds. Textbook of Children’s Environmental Health. New York, NY: Oxford University Press, December 13, 2013, Chapter 9, pp. 83-88. R835437 (2014)
Book Chapter Chronic nicotine effects on memory and nicotine self-administration:Age of exposure is key. None Levin ED Levin ED. Chronic nicotine effects on memory and nicotine self-administration: age of exposure is key. In: Aschner M, Costa LG, eds. Advances in Neurotoxicology, Volume 2, San Diego, CA: Academic Press, 2018, Chapter 6, pp. 189-196. R835437 (2017)
Book Chapter Developmental neurotoxicity of nicotine and tobacco. None Levin ED, Abreu-Villaca Y Levin ED, Abreu-Villaca Y. Developmental neurotoxicity of nicotine and tobacco. In: Slikker Jr. W, Paule MG,Wang C, eds. Handbook of Developmental Neurotoxicology, 2nd Edition, San Diego, CA: Academic Press, 2018, Chapter 39, pp. 439-452. R835437 (2017)
Book Chapter DNA methylation: basic principles. None Moylan CA, Murphy SK Moylan CA, Murphy SK. DNA methylation: basic principles. In: Tollefsbol T, ed. Medical Epigenetics. London: Elsevier, Academic Press, 2016, Chapter 2, pp. 11-31. R835437 (2015)
Book Chapter Systems biology and the epigenome. None Taylor MM, Murphy SK Taylor MM, Murphy SK. Systems biology and the epigenome. In: Fry R, ed. Systems Biology in Toxicology and Environmental Health. Amsterdam: Elsevier, Academic Press, 2015, Chapter 3, pp. 43-56. R835437 (2014)
Journal Article Small-magnitude effect sizes in epigenetic end points are important in children’s environmental health studies: the Children’s Environmental Health and Disease Prevention Research Center’s Epigenetics Working Group. None Breton CV, Marsit CJ, Faustman E, Nadeau K, Goodrich JM, Dolinoy DC, Herbstman J, Holland N, LaSalle JM, Schmidt R, Yousefi P, Perera F, Joubert BR, Wiemels J, Taylor M, Yang IV, Chen R, Hew KM, Hussey Freeland DM, Miller R,Murphy SK Breton CV, Marsit CJ, Faustman E, Nadeau K, Goodrich JM, Dolinoy DC, Herbstman J, Holland N, LaSalle JM, Schmidt R, Yousefi P, Perera F, Joubert BR, Wiemels J, Taylor M, Yang IV, Chen R, Hew KM, Hussey Freeland DM, Miller R, Murphy SK. Small-magnitude effect sizes in epigenetic end points are important in children’s environmental health studies: the Children’s Environmental Health and Disease Prevention Research Center’s Epigenetics Working Group. Environmental Health Perspectives 2017;125(4):511-526. R835437 (2017)
Journal Article Critical developmental periods for effects of low-level tobacco smoke exposure on behavioral performance. None Cauley M, Hall BJ, Abreu-Villaca Y, Junaid S, White H, Kiany A, Slotkin TA, Levin ED Cauley M, Hall BJ, Abreu-Villaca Y, Junaid S, White H, Kiany A, Slotkin TA, Levin ED. Critical developmental periods for effects of low-level tobacco smoke exposure on behavioral performance. Neurotoxicology 2018;68:81-87. R835437 (2017)
Journal Article Association between prepregnancy body mass index and gestational weight gain with size, tempo, and velocity of infant growth: analysis of the Newborn Epigenetic Study cohort. CHILDHOOD OBESITY Fuemmeler BF, Wang L, Iversen ES, Maguire R, Murphy SK, Hoyo C Fuemmeler BF, Wang L, Iversen ES, Maguire R, Murphy SK, Hoyo C. Association between prepregnancy body mass index and gestational weight gain with size, tempo, and velocity of infant growth: analysis of the Newborn Epigenetic Study cohort. Childhood Obesity 2016;12(3):210-218. R835437 (2015)
Journal Article DNA methylation of regulatory regions of imprinted genes at birth and its relation to infant temperament. None Fuemmeler BF, Lee CT, Soubry A, Iversen ES, Huang Z, Murtha AP, Schildkraut JP, Jirtle RL, Murphy SK, Hoyo C Fuemmeler BF, Lee CT, Soubry A, Iversen ES, Huang Z, Murtha AP, Schildkraut JP, Jirtle RL, Murphy SK, Hoyo C. DNA methylation of regulatory regions of imprinted genes at birth and its relation to infant temperament. Genetics and Epigenetics 2016;8:59-67. R835437 (2017)
Journal Article Self-reported prenatal tobacco smoke exposure, AXL gene-body methylation, and childhood asthma phenotypes. None Gao L, Liu X, Millstein J, Siegmund KD, Dubeau L, Maguire RL, Zhang JJ, Fuemmeler BF, Kollins SH, Hoyo C, Murphy SK, Breton CV Gao L, Liu X, Millstein J, Siegmund KD, Dubeau L, Maguire RL, Zhang JJ, Fuemmeler BF, Kollins SH, Hoyo C, Murphy SK, Breton CV. Self-reported prenatal tobacco smoke exposure, AXL gene-body methylation, and childhood asthma phenotypes. Clinical Epigenetics 2018;10(1):98 (11 pp.). R835437 (2017)
Journal Article Cognitive and behavioral impairments evoked by low-level exposure to tobacco smoke components: comparison with nicotine alone. TOXICOLOGIAL SCIENCES Hall BJ, Cauley M, Burke D, Kiany A, Slotkin TA, Levin ED Hall BJ, Cauley M, Burke D, Kiany A, Slotkin TA, Levin ED. Cognitive and behavioral impairments evoked by low-level exposure to tobacco smoke components: comparison with nicotine alone. Toxicological Sciences 2016;151(2):236-244. R835437 (2015)
Journal Article The ventral hippocampal muscarinic cholinergic system plays a key role in sexual dimorphisms of spatial working memory in rats. None Hall BJ, Abreu-Villaca Y, Cauley M, Junaid S, White H, Kiany A, Levin ED Hall BJ, Abreu-Villaca Y, Cauley M, Junaid S, White H, Kiany A, Levin ED. The ventral hippocampal muscarinic cholinergic system plays a key role in sexual dimorphisms of spatial working memory in rats. Neuropharmacology 2017;117:106-113. R835437 (2017)
Journal Article Neighborhood and family environment of expectant mothers may influence prenatal programming of adult cancer risk: discussion and an illustrative DNA methylation example. BIODEMOGRAPHY AND SOCIAL BIOLOGY King KE, Kane JB, Scarbrough P, Hoyo C, Murphy SK King KE, Kane JB, Scarbrough P, Hoyo C, Murphy SK. Neighborhood and family environment of expectant mothers may influence prenatal programming of adult cancer risk: discussion and an illustrative DNA methylation example. Biodemography and Social Biology 2016;62(1):87-104. R835437 (2015)
Journal Article Learning about cognition risk with the radial-arm maze in the developmental neurotoxicology battery. None Levin ED Levin ED. Learning about cognition risk with the radial-arm maze in the developmental neurotoxicology battery. Neurotoxicology and Teratology 2015;52(Pt A):88-92. R835437 (2014)
Journal Article Genotype-epigenotype interaction at the IGF2 DMR. None Murphy SK, Erginer E, Huang Z, Visco Z, Hoyo C Murphy SK, Erginer E, Huang Z, Visco Z, Hoyo C. Genotype-epigenotype interaction at the IGF2 DMR. Genes 2015;6(3):777-789. R835437 (2014)
Journal Article Investigating epigenetic effects of prenatal exposure to toxic metals in newborns: challenges and benefits. MEDICAL EPIGENETICS Nye MD, Fry RC, Hoyo C, Murphy SK Nye MD, Fry RC, Hoyo C, Murphy SK. Investigating epigenetic effects of prenatal exposure to toxic metals in newborns: challenges and benefits. Medical Epigenetics 2014;2(1):53-59. R835437 (2013)
R835437 (2014)
Journal Article In vitro lead exposure changes DNA methylation and expression of IGF2 and PEG1/MEST. None Nye MD, Hoyo C, Murphy SK Nye MD, Hoyo C, Murphy SK. In vitro lead exposure changes DNA methylation and expression of IGF2 and PEG1/MEST. Toxicology In Vitro 2015;29(3):544-550. R835437 (2014)
Journal Article Maternal blood lead concentrations, DNA methylation of MEG3 DMR regulating the DLK1/MEG3 imprinted domain and early growth in a multiethnic cohort. ENVIRONMENTAL EPIGENETICS Nye MD, King KE, Darrah TH, Maguire R, Jima DD, Huang Z, Mendez MA, Fry RC, Jirtle RL, Murphy SK, Hoyo C. Nye MD, King KE, Darrah TH, Maguire R, Jima DD, Huang Z, Mendez MA, Fry RC, Jirtle RL, Murphy SK, Hoyo C. Maternal blood lead concentrations, DNA methylation of MEG3 DMR regulating the DLK1/MEG3 imprinted domain and early growth in a multiethnic cohort. Environmental Epigenetics 2016;2(1):1-8. R835437 (2015)
Journal Article Prenatal smoke exposure and ADHD: advancing the field. None Schechter JC, Kollins SH Schechter JC, Kollins SH. Prenatal smoke exposure and ADHD: advancing the field. Pediatrics 2017;139(2):e20163481 (2 pp.). R835437 (2017)
Journal Article Impact of smoking ban on passive smoke exposure in pregnant non-smokers: using cotinine as a biomarker of exposure. None Schechter JC, Fuemmeler BF, Hoyo C, Murphy SK, Zhang J, Kollins SH Schechter JC, Fuemmeler, BF, Hoyo C, Murphy SK, Zhang JJ, Kollins SH. Impact of smoking ban on passive smoke exposure in pregnant non-smokers: using cotinine as a biomarker of exposure. International Journal of Environmental Research and Public Health 2018;15(1):E83 (16 pp.). R835437 (2017)
Journal Article Adverse benzo[a]pyrene effects on neurodifferentiation are altered by other neurotoxicant coexposures: interactions with dexamethasone, chlorpyrifos, or nicotine in PC12 cells. ENVIRONMENTAL HEALTH PERSPECTIVES Slotkin TA, Card J, Seidler FJ Slotkin TA, Card J, Seidler FJ. Adverse benzo[a]pyrene effects on neurodifferentiation are altered by other neurotoxicant coexposures: interactions with dexamethasone, chlorpyrifos, or nicotine in PC12 cells. Environmental Health Perspectives 2013;121(7):825-831. R835437 (2013)
R835437 (2014)
Journal Article Nicotine administration in adolescence reprograms the subsequent response to nicotine treatment and withdrawal in adulthood: sex-selective effects on cerebrocortical serotonergic function. None Slotkin TA, Card J, Seidler FJ Slotkin TA, Card J, Seidler FJ. Nicotine administration in adolescence reprograms the subsequent response to nicotine treatment and withdrawal in adulthood: sex-selective effects on cerebrocortical serotonergic function. Brain Research Bulletin 2014;102:1-8. R835437 (2014)
Journal Article Effects of tobacco smoke on PC12 cell neurodifferentiation are distinct from those of nicotine or benzo[a]pyrene. NEUROTOXICOLOGY AND TERATOLOGY Slotkin TA, Card J, Stadler A, Levin ED, Seidler FJ Slotkin TA, Card J, Stadler A, Levin ED, Seidler FJ. Effects of tobacco smoke on PC12 cell neurodifferentiation are distinct from those of nicotine or benzo[a]pyrene. Neurotoxicology and Teratology 2014;43:19-24. R835437 (2013)
R835437 (2014)
Journal Article Amelioration strategies fail to prevent tobacco smoke effects on neurodifferentiation: nicotinic receptor blockade, antioxidants, methyl donors. None Slotkin TA, Skavicus S, Card J, Levin ED, Seidler FJ Slotkin TA, Skavicus S, Card J, Levin ED, Seidler FJ. Amelioration strategies fail to prevent tobacco smoke effects on neurodifferentiation: nicotinic receptor blockade, antioxidants, methyl donors. Toxicology 2015;333:63-75. R835437 (2014)
Journal Article Developmental neurotoxicity of tobacco smoke directed toward cholinergic and serotonergic systems:more than just nicotine. None Slotkin TA, Skavicus S, Card J, Stadler A, Levin ED, Seidler FJ Slotkin TA, Skavicus S, Card J, Stadler A, Levin ED, Seidler FJ. Developmental neurotoxicity of tobacco smoke directed toward cholinergic and serotonergic systems: more than just nicotine. Toxicological Sciences 2015;147(1):178-189. R835437 (2014)
Journal Article Adolescents and adults differ in the immediate and long-term impact of nicotine administration and withdrawal on cardiac norepinephrine. BRAIN RESEARCH BULLETIN Slotkin TA, Stadler A, Skavicus S, Seidler FJ Slotkin TA, Stadler A, Skavicus S, Seidler FJ. Adolescents and adults differ in the immediate and long-term impact of nicotine administration and withdrawal on cardiac norepinephrine. Brain Research Bulletin 2016;122:71-75. R835437 (2015)
Journal Article Diverse neurotoxicants target the differentiation of embryonic neural stem cells into neuronal and glial phenotypes. None Slotkin TA, Skavicus S, Card J, Levin ED, Seidler FJ Slotkin TA, Skavicus S, Card J, Levin ED, Seidler FJ. Diverse neurotoxicants target the differentiation of embryonic neural stem cells into neuronal and glial phenotypes. Toxicology 2016;372:42-51. R835437 (2016)
R835437 (2017)
Journal Article Is there a critical period for the developmental neurotoxicity of low-level tobacco smoke exposure? None Slotkin TA, Stadler A, Skavicus S, Card J, Ruff J, Levin ED, Seidler FJ Slotkin TA, Stadler A, Skavicus S, Card J, Ruff J, Levin ED, Seidler FJ. Is there a critical period for the developmental neurotoxicity of low-level tobacco smoke exposure? Toxicological Sciences 2017;155(1):75-84. R835437 (2017)
Journal Article A. None Slotkin, T Slotkin, T.A., Stadler, A., Skavicus, S., Card, J., Ruff, J., Levin, E.D., Seidler, F.J. 2016. Is there a critical period for the developmental neurotoxicity of low-level tobacco smoke exposure? Toxicological Sciences. DOW:10.1093. R835437 (2016)
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Journal Article Imprinted genes and the environment: links to the toxic metals arsenic, cadmium, lead and mercury. None Smeester L, Yosim AE, Nye MD, Hoyo C, Murphy SK, Fry RC Smeester L, Yosim AE, Nye MD, Hoyo C, Murphy SK, Fry RC. Imprinted genes and the environment: links to the toxic metals arsenic, cadmium, lead and mercury. Genes 2014;5(2):477-496. R835437 (2014)
Journal Article Paternal environmental legacy: evidence for epigenetic inheritance through the male germ line. BIOESSAYS Soubry A, Hoyo C, Jirtle RL, Murphy SK Soubry A, Hoyo C, Jirtle RL, Murphy SK. A paternal environmental legacy: evidence for epigenetic inheritance through the male germ line. BioEssays 2014;36(4):359-371. R835437 (2013)
R835437 (2014)
Journal Article DNA methylation of imprinted genes in Mexican-American newborn children with prenatal phthalate exposure. None Tindula G, Murphy SK, Grenier C, Huang Z, Huen K, Escudero-Fung M, Bradman A, Eskenazi B, Hoyo C, Holland N Tindula G, Murphy SK, Grenier C, Huang Z, Huen K, Escudero-Fung M, Bradman A, Eskenazi B, Hoyo C, Holland N. DNA methylation of imprinted genes in Mexican-American newborn children with prenatal phthalate exposure. Epigenomics 2018;10(7):1011-1026. R835437 (2017)
Journal Article Maternal stress, preterm birth, and DNA methylation at imprint regulatory sequences in humans. None Vidal AC, Benjamin Neelon SE, Liu Y, Tuli AM, Fuemmeler BF, Hoyo C, Murtha AP, Huang Z, Schildkraut J, Overcash F, Kurtzberg J, Jirtle RL, Iversen ES, Murphy SK Vidal AC, Benjamin Neelon SE, Liu Y, Tuli AM, Fuemmeler BF, Hoyo C, Murtha AP, Huang Z, Schildkraut J, Overcash F, Kurtzberg J, Jirtle RL, Iversen ES, Murphy SK. Maternal stress, preterm birth, and DNA methylation at imprint regulatory sequences in humans. Genetics and Epigenetics 2014;6:37-44. R835437 (2014)
Journal Article -C. None Lee, W Lee, W.-C., Shen, L., Catalano, P.J., Mickley, L.J., and Koutrakis, P. (2017). Effects of Future Temperature Change on PM2.5 Infiltration in the Greater Boston Area. Atmospheric Environment 150, 98-105. R835437 (2016)
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Journal Article Breton, Carmen J. None Carrie V Carrie V. Breton, Carmen J. Marsit, Elaine Faustman, Kari Nadeau, Jaclyn M. Goodrich, Dana C. Dolinoy, Julie Herbstman, Nina Holland, Janine M. LaSalle, Rebecca Schmidt, Paul Yousefi, Frederica Perera, Bonnie R. Joubert, Joseph Wiemels, Michele Taylor, Ivana V. Yang, Rui Chen, Kinjal M. Hew, Deborah M. Hussey Freeland, Rachel Miller, and Susan K. Murphy. 2017. Small-Magnitude Effect Sizes in Epigenetic End Points are Important in Children’s Environmental Health Studies:The Children’s Environmental Health and Disease Prevention Research Center’s Epigenetics Working Group. Environmental Health Perspectives. 2017:125(4) 511-526. R835437 (2016)
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Journal Article Developmental neurotoxicity of nicotine and tobacco. None Levin ED Y Abreu-Villaça Levin ED and Y Abreu-Villaça. Developmental neurotoxicity of nicotine and tobacco. In Handbook of Developmental Neurotoxicology, (C. Wang, M. Paule, and W. Slikker, Jr. eds.), Academic Press, San Diego, 2017. R835437 (2016)
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Journal Article F. None Fleisch, A Fleisch, A.F., Kloog, I., Luttmann-Gibson, H., Gold, D.R., Oken, E., and Schwartz, J.D. (2016). Air Pollution Exposure and Gestational Diabetes Mellitus Among Pregnant Women in Massachusetts:a Cohort Study. Environmental Health 15, 1-9. R834798C005 (Final)
R835437 (2016)
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Journal Article V. None Breton, C Breton, C.V., Marsit, C.J., Faustman, E., Nadeau, K., Goodrich, J.M., Dolinoy, D.C., Herbstman, J., Holland, N., LaSalle, J.M., Schmidt, R., Yousefi, P., Perera, F., Joubert, B.R., Wiemels, J., Taylor, M., Yang, I.V., Chen, R., Hew, K.M., Hussey Freeland, D.M.,Miller, R. and S.K. Murphy. 2016. Small Magnitude Effect Sizes in Epigenetic Endpoints are Important in Children's Environmental Health Studies:The Children's Environmental Health and Disease Prevention Research Center's Epigenetics Working Group. Environmental Health Perspectives (in press) DOI:10.1289/EHP595. R835437 (2016)
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