Grantee Research Project Results

2002 Progress Report: Statistics and Data Core

EPA Grant Number: R827355C009
Subproject: this is subproject number 009 , established and managed by the Center Director under grant R827355
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
Center: Center for Air, Climate, and Energy Solutions
Center Director: Robinson, Allen
Title: Statistics and Data Core
Investigators: Sheppard, Lianne (Elizabeth) A. , Lumley, Thomas
Current Investigators: Sheppard, Lianne (Elizabeth) A. , Wakefield, Jon , Sampson, Paul , Lumley, Thomas
Institution: University of Washington
EPA Project Officer: Chung, Serena
Project Period: June 1, 1999 through May 31, 2004 (Extended to May 31, 2005)
Project Period Covered by this Report: June 1, 2001 through May 31, 2002
RFA: Airborne Particulate Matter (PM) Centers (1999) RFA Text | Recipients Lists
Research Category: Air Quality and Air Toxics , Particulate Matter , Air

Objective:

The objectives of this research project are to: (1) compile and manage data to support particulate matter (PM) research for the Northwest Research Center for Particulate Air Pollution and Health; (2) utilize existing data for analyses of health effects; (3) ensure quality statistical design and analysis for PM Center research; and (4) identify statistical methodology research needs for PM Center research, and seek resources to perform such research.

Progress Summary:

During the past year, we have undertaken the following activities: (1) active ongoing support of the agricultural burning study database management, data entry, and data validation; (2) active ongoing support of management and analysis of exposure core size-distributed data, including data management, and development of new software and methods; (3) support of animal exposure models—data analysis, drafting of sections of a peer-reviewed manuscript, and some data management and organization; (4) active ongoing support of epidemiology studies activities, particularly with respect to the MITI case-crossover study analysis; (5) active ongoing support of the Center panel study, particularly health effects analyses, and including exposure analyses, and database management of Year 3 data; (6) active ongoing support of the biomarker core research, including the wildfire study; (7) general support of data analysis and data sharing; (8) statistical methods research, particularly in the areas of case-crossover studies, health effects study design, and source apportionment; (9) collaboration with the Sydney brush fire study to examine mortality displacement; and (10) implementation of the analysis plan.

Future Activities:

We will: (1) continue to actively support PM Center research through database management, analysis, and statistical collaboration; (2) continue with a high level of productivity, which may involve cutting back our involvement on projects that have not shown evidence of productivity; and (3) add a significant component of statistical methods research, including several new collaborators. (This will be a new project with the same core investigators.)

Journal Articles on this Report : 5 Displayed | Download in RIS Format

Publications Views
Other subproject views:	All 44 publications	30 publications in selected types	All 29 journal articles
Other center views:	All 209 publications	113 publications in selected types	All 109 journal articles

Publications
Type	Citation	Sub Project	Document Sources
Journal Article	Dominici F, Sheppard L, Clyde M. Health effects of air pollution: a statistical review. International Statistical Review 2003;71(2):243-276.	R827355 (2004) R827355 (Final) R827355C009 (2002) R827355C009 (2003)	Abstract: Wiley-Abstract Exit Other: Prepublication paper Exit
Journal Article	Liu L-JS, Box M, Kalman D, Kaufman J, Koenig J, Larson T, Lumley T, Sheppard L, Wallace L. Exposure assessment of particulate matter for susceptible populations in Seattle. Environmental Health Perspectives 2003;111(7):909-918.	R827355 (2004) R827355 (Final) R827355C003 (Final) R827355C009 (2002)	Full-text from PubMed Abstract from PubMed Associated PubMed link Full-text: ResearchGate - Abstract & Full Text PDF Exit
Journal Article	Lumley T, Sheppard L. Time series analyses of air pollution and health:straining at gnats and swallowing camels? Epidemiology 2003;14(1):13-14.	R827355 (2004) R827355 (Final) R827355C009 (2002)	Abstract from PubMed Full-text: LWW-Full Text HTML Exit Abstract: LWW - Abstract HTML Exit
Journal Article	Slaughter JC, Lumley T, Sheppard L, Koenig JQ, Shapiro GG. Effects of ambient air pollution on symptom severity and medication use in children with asthma. Annals of Allergy Asthma & Immunology 2003;91(4):346-353.	R827355 (Final) R827355C002 (2003) R827355C002 (Final) R827355C009 (2002)	Abstract from PubMed Abstract: Annals of Allergy Asthma & Immunology Exit
Journal Article	Slaughter JC, Kim E, Sheppard L, Sullivan JH, Larson TV, Claiborn C. Association between particulate matter and emergency room visits, hospital admissions and mortality in Spokane, Washington. Journal of Exposure Analysis and Environmental Epidemiology 2005;15(2):153-159.	R827355 (Final) R827355C008 (Final) R827355C009 (2002) R827355C009 (2003) R827355C009 (Final) R828678C010 (2003) R828678C010 (2004) R828678C010 (2005) R828678C010 (2006) R828678C010 (2007) R828678C010 (Final)	Abstract from PubMed Full-text: JESEE-Full Text PDF Exit Abstract: JESEE-Abstract & Full Text HTML Exit Other: ResearchGate - Abstract & Full Text PDF Exit

Supplemental Keywords:

air pollution, air pollutants, particulate matter, PM, fine particulates, PM2.5, fine particles, health effects, health effects analyses, statistical design, statistical methodology, agricultural burning, data management, software, data analysis, epidemiology studies, biomarker research, source apportionment., RFA, Health, Scientific Discipline, PHYSICAL ASPECTS, Air, ENVIRONMENTAL MANAGEMENT, Geographic Area, particulate matter, air toxics, Environmental Chemistry, Health Risk Assessment, Air Pollutants, Epidemiology, State, Air Pollution Effects, Northwest, Risk Assessments, Susceptibility/Sensitive Population/Genetic Susceptibility, Biochemistry, Physical Processes, genetic susceptability, Atmospheric Sciences, Risk Assessment, ambient aerosol, ambient air quality, biostatistics, health effects, particulates, sensitive populations, cardiopulmonary responses, health risks, human health effects, morbidity, toxicology, exposure and effects, acute cardiovascular effects, dose-response, exposure, hazardous air pollutants, epidemelogy, air pollution, Human Health Risk Assessment, particle exposure, cardiopulmonary response, human exposure, inhalation, atmospheric aerosols, ambient particle health effects, mortality studies, air pollutant, PM, human susceptibility, mortality, California (CA), biomarker based exposure inference, aerosols, air quality, atmospheric chemistry, cardiovascular disease, exposure assessment, human health risk, biomarker, particle transport, toxics

Relevant Websites:

http://depts.washington.edu/pmcenter/ Exit

Progress and Final Reports:

Original Abstract

Main Center Abstract and Reports:

R827355 Center for Air, Climate, and Energy Solutions

Subprojects under this Center: (EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
R827355C001 Epidemiologic Study of Particulate Matter and Cardiopulmonary Mortality
R827355C002 Health Effects
R827355C003 Personal PM Exposure Assessment
R827355C004 Characterization of Fine Particulate Matter
R827355C005 Mechanisms of Toxicity of Particulate Matter Using Transgenic Mouse Strains
R827355C006 Toxicology Project -- Controlled Exposure Facility
R827355C007 Health Effects Research Core
R827355C008 Exposure Core
R827355C009 Statistics and Data Core
R827355C010 Biomarker Core
R827355C011 Oxidation Stress Makers

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.