Grantee Research Project Results

Biomarker Core

EPA Grant Number: R827355C010
Subproject: this is subproject number 010 , established and managed by the Center Director under grant R827355
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
Center: Center for Air, Climate, and Energy Solutions
Center Director: Robinson, Allen
Title: Biomarker Core
Investigators: Kalman, Dave , Katz, Bethany , Simpson, Chris , Paulsen, Michael , Dills, Russell
Current Investigators: Kalman, Dave , Simpson, Chris , Dills, Russell
Institution: University of Washington
EPA Project Officer: Chung, Serena
Project Period: June 1, 1999 through May 31, 2004 (Extended to May 31, 2006)
RFA: Airborne Particulate Matter (PM) Centers (1999) RFA Text | Recipients Lists
Research Category: Particulate Matter , Air Quality and Air Toxics , Air

Objective:

The objective of this research project is to develop analytical methods for the determination of organic tracers of woodsmoke, and polycyclic aromatic hydrocarbon (PAH) contribution to particulate matter (PM) in urine and isoprostanes in urine and breath.

Publications and Presentations:

Publications have been submitted on this subproject: View all 19 publications for this subproject | View all 209 publications for this center

Journal Articles:

Journal Articles have been submitted on this subproject: View all 12 journal articles for this subproject | View all 109 journal articles for this center

Supplemental Keywords:

air pollution, air pollutants, particulate matter, PM, polycyclic aromatic hydrocarbons, PAHs, isoprostanes in urine, isoprostanes in breath, woodsmoke, organic tracers, methoxyphenols, levoglucosan, Seattle, Washington, WA, indoor exposure, outdoor exposure, biomarker, urinary methoxyphenol biomarker, high biomass smoke, dithiothreitol assay, oxidative potential of PM, ELISA, isoprostanes, health effects, fine particles., Health, RFA, Air, Scientific Discipline, PHYSICAL ASPECTS, Geographic Area, ENVIRONMENTAL MANAGEMENT, Susceptibility/Sensitive Population/Genetic Susceptibility, Health Risk Assessment, Physical Processes, Risk Assessments, State, particulate matter, genetic susceptability, Environmental Chemistry, Epidemiology, Air Pollution Effects, Northwest, Atmospheric Sciences, Biochemistry, Toxicology, Air Pollutants, air toxics, Risk Assessment, aerosols, air quality, hazardous air pollutants, health effects, health risks, Human Health Risk Assessment, sensitive populations, California (CA), epidemelogy, environmental hazard exposures, ambient aerosol, atmospheric chemistry, human exposure, mortality, cardiopulmonary responses, morbidity, exposure, particulates, ambient particle health effects, biostatistics, atmospheric aerosols, particle transport, toxics, air pollution, ambient air quality, cardiovascular disease, dose-response, human health effects, human health risk, biomarker, human susceptibility, biomarker based exposure inference, acute cardiovascular effects, cardiopulmonary response, exposure assessment, inhalation, particle exposure, exposure and effects

Progress and Final Reports:

Main Center Abstract and Reports:

R827355 Center for Air, Climate, and Energy Solutions

Subprojects under this Center: (EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
R827355C001 Epidemiologic Study of Particulate Matter and Cardiopulmonary Mortality
R827355C002 Health Effects
R827355C003 Personal PM Exposure Assessment
R827355C004 Characterization of Fine Particulate Matter
R827355C005 Mechanisms of Toxicity of Particulate Matter Using Transgenic Mouse Strains
R827355C006 Toxicology Project -- Controlled Exposure Facility
R827355C007 Health Effects Research Core
R827355C008 Exposure Core
R827355C009 Statistics and Data Core
R827355C010 Biomarker Core
R827355C011 Oxidation Stress Makers

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.