Grantee Research Project Results

Health Effects

EPA Grant Number: R827355C002
Subproject: this is subproject number 002 , established and managed by the Center Director under grant R827355
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
Center: Water Environment and Reuse Foundation's National Center for Resource Recovery and Nutrient Management
Center Director: Olabode, Lola
Title: Health Effects
Investigators: Koenig, Jane Q. , Sheppard, Lianne (Elizabeth) A. , Kaufman, Joel D. , Larson, Timothy V. , Trenga, Carol , Sullivan, Jeff , Jansen, Karen , Liu, Sally , Lumley, Thomas
Current Investigators: Koenig, Jane Q. , Lippmann, Morton , Sheppard, Lianne (Elizabeth) A. , Larson, Timothy V. , Jansen, Karen , Allen, Ryan , Mar, Therese , Lumley, Thomas
Institution: University of Washington
EPA Project Officer: Chung, Serena
Project Period: June 1, 1999 through May 31, 2004 (Extended to May 31, 2006)
Project Amount: Refer to main center abstract for funding details.
RFA: Airborne Particulate Matter (PM) Centers (1999) RFA Text | Recipients Lists
Research Category: Particulate Matter , Air Quality and Air Toxics , Air

Objective:

This research project is a health effects panel study that involves comprehensive health monitoring of one healthy and three susceptible subpopulations in Seattle, Spokane, and other cities. The susceptible individuals proposed for study are adults who are 65 years of age or older and have chronic obstructive pulmonary disease (COPD) or cardiovascular disease or children with asthma. The health endpoints to be measured in adult subjects are peak flow, pulse rate, pulse oximetry, blood pressure, and heart rate variability. The health endpoints to be measured in the children with asthma are pulmonary function and symptoms. Personal exposure measurements necessary for associating the health effects with air pollutants will be collected on study participants in Project 2b.

Publications and Presentations:

Publications have been submitted on this subproject: View all 27 publications for this subproject | View all 209 publications for this center

Journal Articles:

Journal Articles have been submitted on this subproject: View all 18 journal articles for this subproject | View all 109 journal articles for this center

Supplemental Keywords:

ambient particles, fine particles, combustion, health, exposure, biostatistics, susceptibility., Health, RFA, Air, Scientific Discipline, Geographic Area, Waste, Susceptibility/Sensitive Population/Genetic Susceptibility, Health Risk Assessment, Risk Assessments, State, particulate matter, genetic susceptability, Environmental Chemistry, Incineration/Combustion, Epidemiology, indoor air, Northwest, Biochemistry, Toxicology, air toxics, environmental hazard exposures, air quality, health risks, Human Health Risk Assessment, health effects, combustion contaminants, incineration, indoor air quality, sensitive populations, aerosols, California (CA), age dependent response, asthma, ambient aerosol, combustion emissions, elderly, risk assessment, atmospheric chemistry, mortality, human exposure, cardiopulmonary responses, animal model, morbidity, combustion, allergens, children, exposure, particulates, ambient particle health effects, toxics, biostatistics, particle transport, ambient air, air pollutants, atmospheric aerosols, cardiovascular disease, human health risk, air pollution, human health effects, human susceptibility, ambient air quality, airway disease, cardiopulmonary response, inhalation, exposure assessment, exposure and effects

Progress and Final Reports:

Main Center Abstract and Reports:

R827355 Water Environment and Reuse Foundation's National Center for Resource Recovery and Nutrient Management

Subprojects under this Center: (EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
R827355C001 Epidemiologic Study of Particulate Matter and Cardiopulmonary Mortality
R827355C002 Health Effects
R827355C003 Personal PM Exposure Assessment
R827355C004 Characterization of Fine Particulate Matter
R827355C005 Mechanisms of Toxicity of Particulate Matter Using Transgenic Mouse Strains
R827355C006 Toxicology Project -- Controlled Exposure Facility
R827355C007 Health Effects Research Core
R827355C008 Exposure Core
R827355C009 Statistics and Data Core
R827355C010 Biomarker Core
R827355C011 Oxidation Stress Makers

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.