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Records 1 to 25 of 68 records from [ORD-NCCT] published between 03/18/2013 and 03/18/2018 from author Keith Houck

2018
Kuo, B., J. Wills, P. White, F. Marchetti, A. Nong, A. Williams, K. Houck, R. Tice, AND C. Yauk. A High-throughput Analytical Framework for Efficient Analysis of In Vitro Micronucleus (MN) Dose-response Data. Health Canada Science Forum, OttawaC, March 08 - 09, 2018. https://doi.org/10.23645/epacomptox.6947897
Sipes, N., R. Huang, K. Shockley, M. Martin, A. Shapiro, J. Addington, S. Auerbach, R. Paules, R. Judson, K. Houck, H. Hong, AND J. Hsieh. Confidence in Fitting and Hitting Concentration-Response Data: Tox21 10k Library Pipeline Comparison. Presented at Society of Toxicology Annual Meeting, San Antonio, TX, March 11 - 15, 2018. https://doi.org/10.23645/epacomptox.6945911
Flood, S. AND K. Houck. Development and Distribution of ToxCast and Tox21 HTS Assay Method Descriptions. CompTox Communities of Practice, RTP,NC, January 25, 2018.
Houck, K. AND A. Bone. Filling in the Gaps: The Role Functional Genomics Can Play in 21st Century Toxicology. Presented at Society of Toxicology Meeting, San Antonio, TX, March 11 - 15, 2018. https://doi.org/10.23645/epacomptox.6946166
Houck, K., A. Bone, K. Paul-Friedman, C. Hsu, S. Sakamuru, M. Xia, R. Huang, V. Soni, D. Stavreva, AND K. Crofton. Screening the 10K Tox21 chemical library for thyroid hormone receptor modulators. Society of Toxicology, San Antonio, TX, March 11 - 15, 2018.
Houck, K. Update on the ToxCast Chemical Prioritization Project. Presented at California Breast Cancer Research Program, Oakland, CA, February 12 - 14, 2018. https://doi.org/10.23645/epacomptox.7029203
2017
Houck, K., C. LaLone, A. Bone, R. Judson, M. Martin, Dan Villeneuve, G. Ankley, A. Medvedev, AND S. Markarov. A Multi-Receptor and Multi-Species Assay for Potential Endocrine Disruptor Targets (SLAS meeting). Presented at 2017 SLAS meeting, Washington, DC, February 04 - 08, 2017. https://doi.org/10.23645/epacomptox.5181265
Kleinstreuer, N., P. Ceger, Eric Watt, M. Martin, K. Houck, P. Browne, R. Thomas, W. Casey, D. Dix, D. Allen, S. Sakamuru, M. Xia, R. Huang, AND R. Judson. Development and Validation of a Computational Model for Androgen Receptor Activity. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 30(4):946-964, (2017).
Flood, S., K. Houck, AND Chris Grulke. Development of a Context-Rich Database of ToxCast Assay Annotations (SOT). Presented at SOT Annual Meeting, Baltimore, MD, March 12 - 16, 2017. https://doi.org/10.23645/epacomptox.5178610
Houck, K. EPA’s ToxCast Program: Update on CBCRP-Relevant Work (CBCRP Annual Meeting). Presented at CBCRP Annual Meeting, Berkeley, California, April 06, 2017. https://doi.org/10.23645/epacomptox.5056819
Houck, K., C. LaLone, R. Judson, M. Martin, Dan Villeneuve, G. Ankley, A. Medvedev, AND S. Markarorav. Evaluation of an In Vitro Multi-Receptor and Multi-Species Assay for Potential Endocrine Disruptor Targets (SOT). Presented at SOT National Meeting, Baltimore, MD, March 12 - 16, 2017.
Bone, A., M. Xia, S. Sakamuru, R. Huang, R. Houtman, R. van Beuningen, Eric Watt, N. Kleinstreuer, R. Judson, AND K. Houck. Identification of Androgen Receptor Antagonists using Tox21 qHTS Data and the MARCoNI Assay. Society of Toxicology Annual Meeting, Baltimore,MD, March 12 - 16, 2017. https://doi.org/10.23645/epacomptox.6791795.v2
Lynch, C., S. Sakamuru, R. Huang, D. Stavea, L. Varticovski, G. Hager, Richard S. Judson, Keith A. Houck, N. Kleinstreuer, W. Casey, R. Paules, A. Simeonov, AND M. Xia. Identifying Environmental Chemicals as Agonists of the Androgen Receptor by Applying a Quantitative High-throughput Screening Platform. TOXICOLOGY. Elsevier Science Ltd, New York, NY, 385:48-58, (2017).
Judson, R., K. Houck, T. Knudsen, Eric Watt, S. Mosher, T. Tal, AND S. Padilla. Modeling Zebrafish Developmental Toxicity using a Concurrent In vitro Assay Battery (SOT). Presented at SOT 2017, Baltimore, MD, March 12 - 16, 2017. https://doi.org/10.23645/epacomptox.5178586
Judson, R., K. Houck, Eric Watt, AND R. Thomas. On Selecting a Minimal Set of In Vitro Assays to Reliably Determine Estrogen Agonist Activity. REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, 91:39-49, (2017).
Harrill, J., M. Martin, K. Houck, R. Judson, K. Crofton, AND R. Thomas. Optimization Of A High-Throughput Transcriptomic (HTTr) Bioactivity Screen In MCF7 Cells Using Targeted RNA-Seq (SOT). Presented at SOT annual meeting, Baltimore, MD, March 12 - 16, 2017. https://doi.org/10.23645/epacomptox.5176789
Paul-Friedman, K., J. Zhao, R. Huang, M. Xia, K. Crofton, AND K. Houck. Screening the Tox21 10K library for thyroid stimulating hormone receptor agonist and antagonist activity (SOT annual meeting). Presented at SOT Annual Meeting, Baltimore, Maryland, March 12 - 16, 2017. https://doi.org/10.23645/epacomptox.5176897
Flood, S. AND K. Houck. ToxCast Assay Descriptions (originally presented at CSS meeting, and will be released to external stakeholders). Presented at CSS monthly meeting, RTP, NC, April 10, 2017.
Houck, K. Toxicity Testing in the 21st Century EPA’s CompTox Approach (TAMU CVM lecture)EPA’s CompTox Approach (TAMU CVM). Presented at TA&MU CVM lecture, College Station, Texas, April 28, 2017.
Thomas, R., D. Zink, L. Loo, K. Houck, H. Yu, I. Shah, F. Ginhoux, AND T. Knudsen. US EPA - A*Star Partnership - Accelerating the Acceptance of Next-Generation Sciences and Their Application to Regulatory Risk Assessment (A*Star Symposium, Singapore). Presented at A*STAR Symposium, Singapore, Singapore, SINGAPORE, February 04 - 08, 2017.
2016
Judson, R., K. Houck, M. Martin, A. Richard, T. Knudsen, I. Shah, S. Little, J. Wambaugh, Woodrow Setzer, P. Kothiya, J. Phuong, D. Filer, D. Smith, D. Reif, D. Rotroff, N. Kleinstreuer, N. Sipes, M. Xia, R. Huang, K. Crofton, AND R. Thomas. Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 152(2):323-339, (2016).
Bone, A., G. Patlewicz, AND K. Houck. Evaluation and comparison of bisphenol A analog activity using ToxCast data (SOT). Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 13 - 17, 2016. https://doi.org/10.23645/epacomptox.5176606
Karmaus, A., D. Filer, M. Martin, AND K. Houck. Evaluation of food-relevant chemicals in the ToxCast high-throughput screening program. FOOD AND CHEMICAL TOXICOLOGY. Elsevier Science Ltd, New York, NY, 92:188-196, (2016).