||Asbestos Exposure and Gastrointestinal Malignancy Review and Meta-Analysis.
Frumkin, H. ;
Berlin, J. ;
||Harvard School of Public Health, Boston, MA.;Health Effects Research Lab., Research Triangle Park, NC.
Public health ;
Gastrointestinal neoplasms ;
Occupational exposure ;
Health hazards ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
The epidemiologic literature linking asbestos exposure with gastrointestinal malignancy is reviewed. Problems in comparing studies are discussed, appropriate strategies for comparison are developed, and study results are pooled using a model which accounts for both intrastudy and interstudy variability. Stratification of cohorts by dose reveals that significant asbestos exposure, as indicated by a lung cancer standardized mortality ratio (SMR) of at least 200, is associated with an elevated gastrointestinal cancer SMR for five or six end points examined. (Copyright (c) 1988 Alan R. Liss, Inc.)