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RECORD NUMBER: 12 OF 23

Main Title Evaluation of the Mutagenic Potential of High Drop Point Lithium Hydroxystearate Grease (XRR 185A) in the Mouse Lymphoma (L5178Y/TK(sup +/-)) Assay with Cover Letter.
CORP Author Mobil Oil Corp., New York.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Publisher 27 Jun 1983
Year Published 1983
Report Number OTS-878213625;
Stock Number OTS-0206317
Additional Subjects Mutagenic pathways ; Lithium ; Mouse ; Lymphoma ; Paraffin ; Toxicity ; Evaluation ; Cell cultures ; Mutations ; Mammals ; Assaying ; Carcinogens ; Chemical analysis ; Solvents ; Lithium hydroxystearate grease ; Chlorinated paraffins
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NTIS  OTS-0206317 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 57p
Abstract
The Mouse Lymphoma ( L5178Y/TK+/-) Mutagenesis Assay was used to determine the potential of high drop point lithium hydroxystearate grease (XRR 185A) to induce mutations in mammalian cells grown in culture. This assay is a sensitive indicator of the mutagenic potential of compounds from a wide variety of chemical classes. Furthermore, it has the advantage of detecting several classes of carcinogens that are weakly mutagenic or non-mutagenic in the Ames Salmonella/ mammalian microsomal activation assay.