Record Display for the EPA National Library Catalog


Main Title Health assessment document for inorganic arsenic : final report.
Author Jacobson-Kram, D. ; Mushak, P. ; Piscator, M. ; Sivulka, D. J. ; Chu, M.
CORP Author United States. Environmental Protection Agency. Environmental Criteria and Assessment Office.
Publisher U.S. Environmental Protection Agency, Office of Research and Development, Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office,
Year Published 1984
Report Number EPA 600/8-83-021F
Stock Number PB84-190891
OCLC Number 12940146
Subjects Arsenic--Toxicology ; Carcinogens
Additional Subjects Arsenic--Toxicology ; Carcinogens ; Public health ; Arsenic inorganic compounds ; Toxicology ; Environmental surveys ; Industrial wastes ; Smelting ; Biocides ; Glass industry ; Air pollution ; Absorption ; Potable water ; Oxidation reduction reactions ; Mutagens ; Metabolism ; Ingestion(Biology) ; Pathology ; Exposure ; Humans ; Animals ; Sources ; Ecology ; Risk ; Malignant neoplasms ; Water pollution ; Soils ; Foods ; Biotransformation ; Cancer
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EHBD  EPA-600/8-83-021F CEMM/ACESD Library/Narragansett,RI 03/23/2007
EJED  EPA 600/8-83-021F OCSPP Chemical Library/Washington,DC 01/26/2001
ELBD ARCHIVE EPA 600-8-83-021F Received from HQ AWBERC Library/Cincinnati,OH 10/04/2023
ELBD  EPA 600-8-83-021F AWBERC Library/Cincinnati,OH 01/28/1989
EMBD  EPA/600/8-83/021F NRMRL/GWERD Library/Ada,OK 12/24/1992
ERAD  EPA 600/8-83-021F Region 9 Library/San Francisco,CA 02/19/2013
ESAD  EPA 600-8-83-021F Region 10 Library/Seattle,WA 07/29/2005
NTIS  PB84-190891 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 1 v. (various pagings) : ill. ; 28 cm.
Inorganic arsenic, predominantly the tri- and pentavalent forms, is emitted to the environment primarily through smelting activity, biocide use and glass manufacturing. Monitoring data indicate a concentration of equal to or less than 0.1 microgram/cu m for most locations. Major routes of absorption of inorganic arsenic in the general population are inhalation and ingestion. Inhaled inorganic arsenic deposited in the lungs is eventually absorbed. Most ingested soluble inorganic arsenic is absorbed, whereas insoluble forms pass through the gastrointestinal tract with negligible absorption. Inorganic arsenic metabolism in man is complicated by biotransformation processes which include the methylation and oxidation-reduction interconversion of inorganic arsenic. Long-term accumulation of inorganic arsenic does not generally occur in physiologically active compartments in the body; renal clearance appears to be the major route of excretion of absorbed inorganic arsenic. Acute symptoms of inorganic arsenic poisoning include severe gastrointestinal damage, facial edema, cardiovascular reactions, peripheral nervous system disturbances, and hematopoietic system effects. General population concerns arising from long-term exposures to moderate levels of inorganic arsenic include respiratory tract cancer, skin cancer, non-cancerous skin lesions, peripheral neuropathological effects and cardiovascular effects. There appears to be a nutritional requirement for low levels of inorganic arsenic in certain experimental animals; however, this requirement has not yet been established in man.
"March 1984." "EPA-600/8-83-021F." Includes bibliographical references.