Grantee Research Project Results
Selected Publications Details for Grant Number R832734
PON1 as a Predictor of Differential Susceptibility of Children to Organophosphate Pesticides
RFA:
Early Indicators of Environmentally Induced Disease (2004)
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Reference Type | Reference Title | Journal | Author | Citation | Progress Report Year | Document Sources |
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Journal Article | Prenatal exposure to organophosphate pesticides and IQ in 7-year-old children. | ENVIRONMENTAL HEALTH PERSPECTIVES | Bouchard MF, Chevrier J, Harley KG, Kogut K, Vedar M, Calderon N, Trujillo C, Johnson C, Bradman A, Barr DB, Eskenazi B | Bouchard MF, Chevrier J, Harley KG, Kogut K, Vedar M, Calderon N, Trujillo C, Johnson C, Bradman A, Barr DB, Eskenazi B. Prenatal exposure to organophosphate pesticides and IQ in 7-year-old children. Environmental Health Perspectives 2011;119(8):1189-1195. |
R831710 (Final) R832734 (Final) R834513 (2010) R834513 (2011) R834513 (2012) R834513 (2013) R834513 (2015) R834513 (2016) R834513 (Final) R834513C001 (2010) R834513C001 (2011) R834513C001 (2012) |
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Journal Article | Determinants of organophosphorus pesticide urinary metabolite levels in young children living in an agricultural community. | INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH | Bradman A, Castorina R, Barr DB, Chevrier J, Harnly ME, Eisen EA, McKone TE, Harley K, Holland N, Eskenazi B | Bradman A, Castorina R, Barr DB, Chevrier J, Harnly ME, Eisen EA, McKone TE, Harley K, Holland N, Eskenazi B. Determinants of organophosphorus pesticide urinary metabolite levels in young children living in an agricultural community. International Journal of Environmental Research and Public Health 2011;8(4):1061-1083. |
R831710 (Final) R832734 (Final) R834513 (2010) R834513 (2011) R834513 (2012) R834513 (2013) R834513 (2015) R834513 (2016) R834513 (Final) R834513C001 (2010) R834513C001 (2011) R834513C002 (2010) R834513C002 (2011) R834513C002 (2012) R834513C003 (2010) R834513C003 (2011) R834513C003 (Final) |
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Journal Article | Organophosphate pesticide exposure among pome and non-pome farmworkers: a subgroup analysis of a community randomized trial. | JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE | Coronado GD, Vigoren EM, Griffith WC, Faustman EM, Thompson B | Coronado GD, Vigoren EM, Griffith WC, Faustman EM, Thompson B. Organophosphate pesticide exposure among pome and non-pome farmworkers:a subgroup analysis of a community randomized trial. Journal of Occupational and Environmental Medicine 2009;51(4):500-509. |
R831709 (2007) R832734 (Final) R834514 (2011) R834514 (Final) R834514C001 (Final) |
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Journal Article | Centros de investigación de salud medioambiental y prevención de enfermedades de niños. | ACTA TOXICOLOGICA ARGENTINA | Eskenazi B | Eskenazi B. Centros de investigación de salud medioambiental y prevención de enfermedades de niños. Desde 1998 al presente. Acta Toxicologica Argentina 2006;14(Suppl):60-62. |
R831710 (2005) R831710 (Final) R831710C001 (2007) R832734 (2006) |
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Journal Article | Indicadores biologicos de exposicion a pesticidas y su relacion con la salud de los ninos. | ACTA TOXICOLOGICA ARGENTINA | Eskenazi B, Bradman A, Harley K, Holland N | Eskenazi B, Bradman A, Harley K, Holland N. Indicadores biologicos de exposicion a pesticidas y su relacion con la salud de los ninos. Acta Toxicologica Argentina 2006;14(Supplement):63-65. |
R831710 (2005) R831710C001 (2007) R831710C002 (2007) R832734 (2006) |
not available |
Journal Article | Pesticide toxicity and the developing brain. | BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY | Eskenazi B, Rosas LG, Marks AR, Bradman A, Harley K, Holland N, Johnson C, Fenster L, Barr DB | Eskenazi B, Rosas LG, Marks AR, Bradman A, Harley K, Holland N, Johnson C, Fenster L, Barr DB. Pesticide toxicity and the developing brain. Basic & Clinical Pharmacology & Toxicology 2008;102(2):228-236. |
R831710 (2005) R831710 (Final) R832734 (2007) R832734 (Final) |
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Journal Article | PON1 and neurodevelopment in children from the CHAMACOS Study exposed to organophosphate pesticides in utero. | ENVIRONMENTAL HEALTH PERSPECTIVES | Eskenazi B, Huen K, Marks A, Harley KG, Bradman A, Barr DB, Holland N | Eskenazi B, Huen K, Marks A, Harley KG, Bradman A, Barr DB, Holland N. PON1 and neurodevelopment in children from the CHAMACOS study exposed to organophosphate pesticides in utero. Environmental Health Perspectives 2010;118(12):1775-1781. |
R831710 (Final) R832734 (Final) R834513 (2010) R834513 (2011) R834513 (2012) R834513 (2013) R834513 (2015) R834513 (2016) R834513 (Final) R834513C001 (2010) R834513C001 (2011) R834513C003 (2010) R834513C003 (2011) |
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Journal Article | Organophosphate pesticide exposure, PON1, and neurodevelopment in school-age children from the CHAMACOS study. | None | Eskenazi B, Kogut K, Huen K, Harley KG, Bouchard M, Bradman A, Boyd-Barr D, Johnson C, Holland N | Eskenazi B, Kogut K, Huen K, Harley KG, Bouchard M, Bradman A, Boyd-Barr D, Johnson C, Holland N. Organophosphate pesticide exposure, PON1, and neurodevelopment in school-age children from the CHAMACOS study. Environmental Research 2014;134:149-157. |
R826709 (2002) R832734 (Final) R834513 (2014) R834513 (2015) R834513C001 (2014) R834513C001 (2015) |
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Journal Article | Association of organophosphate pesticide exposure and paraoxonase with birth outcome in Mexican-American women. | PLOS ONE | Harley KG, Huen K, Aguilar Schall R, Holland NT, Bradman A, Barr DB, Eskenazi B | Harley KG, Huen K, Aguilar Schall R, Holland NT, Bradman A, Barr DB, Eskenazi B. Association of organophosphate pesticide exposure and paraoxonase with birth outcome in Mexican-American women. PLoS ONE 2011;6(8):e23923 (10 pp.). |
R832734 (Final) R834513 (2010) R834513 (2011) R834513 (2012) R834513 (2013) R834513 (2015) R834513 (2016) R834513 (Final) R834513C001 (2010) R834513C001 (2011) R834513C001 (2012) |
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Journal Article | Paraoxonase polymorphisms, haplotypes, and enzyme activity in Latino mothers and newborns. | ENVIRONMENTAL HEALTH PERSPECTIVES | Holland N, Furlong C, Bastaki M, Richter R, Bradman A, Huen K, Beckman K, Eskenazi B | Holland N, Furlong C, Bastaki M, Richter R, Bradman A, Huen K, Beckman K, Eskenazi B. Paraoxonase polymorphisms, haplotypes, and enzyme activity in Latino mothers and newborns. Environmental Health Perspectives 2006;114(7):985-991. |
R831709 (2005) R831709 (2006) R831709 (2007) R831709C002 (2006) R831710 (2004) R831710 (2005) R831710 (Final) R831710C001 (2007) R831710C003 (2006) R832734 (2006) R832734 (2007) R832734 (Final) |
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Journal Article | Validation of PON1 enzyme activity assays for longitudinal studies. | CLINICA CHIMA ACTA | Huen K, Richter R, Furlong C, Eskenazi B, Holland N | Huen K, Richter R, Furlong C, Eskenazi B, Holland N. Validation of PON1 enzyme activity assays for longitudinal studies. Clinica Chimica Acta 2009;402(1-2):67-74. |
R831709 (2007) R831710 (Final) R832734 (2009) R832734 (Final) R834513 (2010) R834513 (2011) R834513 (Final) |
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Journal Article | Developmental changes in PON1 enzyme activity in young children and effects of PON1 polymorphisms. | ENVIRONMENTAL HEALTH PERSPECTIVES | Huen K, Harley K, Brooks J, Hubbard A, Bradman A, Eskenazi B, Holland N | Huen K, Harley K, Brooks J, Hubbard A, Bradman A, Eskenazi B, Holland N. Developmental changes in PON1 enzyme activity in young children and effects of PON1 polymorphisms. Environmental Health Perspectives 2009;117(10):1632-1638. |
R831710 (Final) R832734 (2009) R832734 (Final) R834513 (2010) R834513 (2011) R834513 (Final) |
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Journal Article | Longitudinal changes in PON1 enzymatic activities in Mexican-American mothers and children with different genotypes and haplotypes. | TOXICOLOGY AND APPLIED PHARMACOLOGY | Huen K, Harley K, Bradman A, Eskenazi B, Holland N | Huen K, Harley K, Bradman A, Eskenazi B, Holland N. Longitudinal changes in PON1 enzymatic activities in Mexican-American mothers and children with different genotypes and haplotypes. Toxicology and Applied Pharmacology 2010;244(2):181-189. |
R832734 (2009) R832734 (Final) R834513 (2010) R834513 (2011) R834513 (Final) |
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Journal Article | Effects of PON polymorphisms and haplotypes on molecular phenotype in Mexican-American mothers and children. | ENVIRONMENTAL AND MOLECULAR MUTAGENESIS | Huen K, Barcellos L, Beckman K, Rose S, Eskenazi B, Holland N | Huen K, Barcellos L, Beckman K, Rose S, Eskenazi B, Holland N. Effects of PON polymorphisms and haplotypes on molecular phenotype in Mexican-American mothers and children. Environmental and Molecular Mutagenesis 2011;52(2):105-116. |
R831710 (Final) R832734 (Final) R834513 (2010) R834513 (2011) R834513 (2012) R834513 (2013) R834513 (2015) R834513 (2016) R834513 (Final) R834513C001 (2010) R834513C001 (2011) |
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Journal Article | Organophosphate pesticide levels in blood and urine of women and newborns living in an agricultural community. | ENVIRONMENTAL RESEARCH | Huen K, Bradman A, Harley K, Yousefi P, Boyd Barr D, Eskenazi B, Holland N | Huen K, Bradman A, Harley K, Yousefi P, Boyd Barr D, Eskenazi B, Holland N. Organophosphate pesticide levels in blood and urine of women and newborns living in an agricultural community. Environmental Research 2012;117:8-16. |
R831710 (Final) R832734 (Final) R834513 (2010) R834513 (2011) R834513 (2012) R834513 (2013) R834513 (2015) R834513 (2016) R834513 (Final) R834513C001 (2010) R834513C001 (2011) R834513C002 (2010) R834513C002 (2012) R834513C002 (2013) R834513C003 (2010) R834513C003 (2011) R834513C003 (2012) |
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Journal Article | Organophosphate pesticide exposure and attention in young Mexican-American children: the CHAMACOS Study. | ENVIRONMENTAL HEALTH PERSPECTIVES | Marks AR, Harley K, Bradman A, Kogut K, Barr DB, Johnson C, Calderon N, Eskenazi B | Marks AR, Harley K, Bradman A, Kogut K, Barr DB, Johnson C, Calderon N, Eskenazi B. Organophosphate pesticide exposure and attention in young Mexican-American children: the CHAMACOS Study. Environmental Health Perspectives 2010;118(12):1768-1774. |
R831710 (Final) R832734 (Final) R834513 (2010) R834513 (2011) R834513 (2012) R834513 (2013) R834513 (2015) R834513 (2016) R834513 (Final) R834513C001 (2010) R834513C001 (2011) |
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Journal Article | Children’s exposure to environmental pollutants and biomarkers of genetic damage: I. Overview and critical issues. | MUTATION RESEARCH/REVIEWS IN MUTATION RESEARCH | Neri M, Bonassi S, Knudsen LE, Sram RJ, Holland N, Ugolini D, Merlo DF | Neri M, Bonassi S, Knudsen LE, Sram RJ, Holland N, Ugolini D, Merlo DF. Children’s exposure to environmental pollutants and biomarkers of genetic damage:I. Overview and critical issues. Mutation Research-Reviews in Mutation Research 2006;612(1):1-13. |
R831710 (Final) R831710C003 (2006) R832734 (2006) R832734 (2007) R832734 (Final) |
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Journal Article | Children’s exposure to environmental pollutants and biomarkers of genetic damage: II. Results of a comprehensive literature search and meta-analysis. | MUTATION RESEARCH/REVIEWS IN MUTATION RESEARCH | Neri M, Ugolini D, Bonassi S, Fucic A, Holland N, Knudsen LE, Sram RJ, Ceppi M, Bocchini V, Merlo DF | Neri M, Ugolini D, Bonassi S, Fucic A, Holland N, Knudsen LE, Sram RJ, Ceppi M, Bocchini V, Merlo DF. Children’s exposure to environmental pollutants and biomarkers of genetic damage: II. Results of a comprehensive literature search and meta-analysis. Mutation Research-Reviews in Mutation Research 2006;612(1):14-39. |
R831710 (Final) R831710C003 (2006) R832734 (2006) R832734 (Final) |
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Journal Article | Maternal prenatal and child organophosphate pesticide exposures and children's autonomic function. | NEUROTOXICOLOGY | Quiros-Alcala L, Alkon AD, Boyce WT, Lippert S, Davis NV, Bradman A, Barr DB, Eskenazi B | Quiros-Alcala L, Alkon AD, Boyce WT, Lippert S, Davis NV, Bradman A, Barr DB, Eskenazi B. Maternal prenatal and child organophosphate pesticide exposures and children's autonomic function. NeuroToxicology 2011;32(5):646-655. |
R832734 (Final) R834513 (2010) R834513 (2011) R834513 (2012) R834513 (2013) R834513 (2015) R834513 (2016) R834513 (Final) R834513C001 (2010) R834513C001 (2011) R834513C001 (2012) |
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Journal Article | Children's exposure to environmental tobacco smoke: using diverse exposure metrics to document ethnic/racial differences. | ENVIRONMENTAL HEALTH PERSPECTIVES | Sexton K, Adgate JL, Church TR, Hecht SS, Ramachandran G, Greaves IA, Fredrickson AL, Ryan AD, Carmella SG, Geisser MS | Sexton K, Adgate JL, Church TR, Hecht SS, Ramachandran G, Greaves IA, Fredrickson AL, Ryan AD, Carmella SG, Geisser MS. Children's exposure to environmental tobacco smoke:using diverse exposure metrics to document ethnic/racial differences. Environmental Health Perspectives 2004;112(3):392-397. |
R826789 (2002) R826789 (Final) R832734 (Final) |
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Journal Article | Ethical issues in measuring biomarkers in children's environmental health. | ENVIRONMENTAL HEALTH PERSPECTIVES | Sly PD, Eskenazi B, Pronczuk J, Sram R, Diaz-Barriga F, Machin DG, Carpenter DO, Surdu S, Meslin EM | Sly PD Eskenazi B, Pronczuk J, Sram R, Diaz-Barriga F, Machin DG, Carpenter DO, Surdu S, Meslin EM. Ethical issues in measuring biomarkers in children's environmental health. Environmental Health Perspectives 2009;117(8):1185-1190. |
R831710 (Final) R832734 (2009) R832734 (Final) R834513 (2010) R834513 (2011) R834513 (Final) |
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Journal Article | Lysophosphatidylcholine hydrolases of human erythrocytes, lymphocytes, and brain: sensitive targets of conserved specificity for organophosphorus delayed neurotoxicants. | TOXICOLOGY AND APPLIED PHARMACOLOGY | Vose SC, Holland NT, Eskenazi B, Casida JE | Vose SC, Holland NT, Eskenazi B, Casida JE. Lysophosphatidylcholine hydrolases of human erythrocytes, lymphocytes, and brain:sensitive targets of conserved specificity for organophosphorus delayed neurotoxicants. Toxicology and Applied Pharmacology 2007;224(1):98-104. |
R831710 (2005) R831710 (Final) R832734 (2007) R832734 (Final) |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.