Grantee Research Project Results
Publications Details for Grant Number R834596C003
Ambient Pollutant/Bioaerosol Effects on Treg Function
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Reference Type | Citation | Progress Report Year | Document Sources |
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Journal Article | Balmes JR. How does diesel exhaust impact asthma? Thorax 2011;66(1):4-6. |
R834596 (2010) R834596 (2011) R834596 (2012) R834596 (Final) R834596C003 (2012) |
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Journal Article | Gale SL, Noth EM , Mann J, Balmes J, Hammond SK, Tager IB. Polycyclic aromatic hydrocarbon exposure and wheeze in a cohort of children with asthma in Fresno, CA. Journal of Exposure Science & Environmental Epidemiology 2012;22(4):386-392. |
R834596 (2010) R834596 (2011) R834596 (2012) R834596 (Final) R834596C003 (2012) |
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Journal Article | Hew KM, Walker AI, Kohli A, Garcia M, Syed A, McDonald-Hyman C, Noth EM, Mann JK, Pratt B, Balmes J, Hammond SK, Eisen EA, Nadeau KC. Childhood exposure to ambient polycyclic aromatic hydrocarbons is linked to epigenetic modifications and impaired systemic immunity in T cells. Clinical & Experimental Allergy 2015;45(1):238-248. |
R834596 (2012) R834596 (Final) R834596C003 (Final) R834786 (Final) R835435 (2014) R835435 (2015) R835435 (2016) R835435 (Final) |
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Journal Article | Kohli A, Garcia MA, Miller RL, Maher C, Humblet O, Hammond SK, Nadeau K. Secondhand smoke in combination with ambient air pollution exposure is associated with increased CpG methylation and decreased expression of IFN-γ in T effector cells and Foxp3 in T regulatory cells in children. Clinical Epigenetics 2012;4(1):17 (16 pp.). |
R834596 (2011) R834596 (2012) R834596 (Final) R834596C003 (2011) R834596C003 (2012) R834596C003 (Final) R834786 (2012) R835435 (Final) |
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Journal Article | Liu J, Zhang L, Winterroth LC, Garcia M, Weiman S, Wong JW, Sunwoo JB, Nadeau KC. Epigenetically mediated pathogenic effects of phenanthrene on regulatory T cells. Journal of Toxicology 2013;2013:967029. |
R834596 (2012) R834596 (Final) R834596C003 (2012) R834596C003 (Final) R834786 (2012) R835435 (Final) |
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Journal Article | Nadeau K, McDonald-Hyman C, Noth EM, Pratt B, Hammond SK, Balmes J, Tager I. Ambient air pollution impairs regulatory T-cell function in asthma. Journal of Allergy and Clinical Immunology 2010;126(4):845-852.e10. |
R834596 (2010) R834596 (2011) R834596C003 (2010) R834596C003 (2011) R834786 (2011) R835435 (Final) |
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Presentation | Balmes J, Nadeau K, Mann J, Gale S, Noth E, Shaw G, Hammond SK, Tager I. Effects of air pollution on immune function and asthma. Presented at the Symposium on Children's Environmental Health Research, California EPA, Oakland, CA, January 11-12, 2012. |
R834596 (2012) R834596 (Final) R834596C003 (2012) |
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Presentation | Balmes J, Padula A, Eisen E, Mann J, Noth E, Lurmann F, Nadeau K, Hammond SK. The effect of chronic exposure to PAHs on lung function in children. Presented at the Symposium on Cumulative Impacts and Children's Environmental Health, Sacramento, CA, January 16-17, 2013. |
R834596 (2012) R834596 (Final) R834596C003 (2012) |
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Presentation | Balmes J. Health impacts of air pollution in the San Joaquin Valley. Presented via the American Lung Association of California Webinar, 2013. |
R834596 (2012) R834596 (Final) R834596C001 (2012) R834596C002 (2012) R834596C003 (2012) |
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Presentation | Hammond SK. The Children's Health and Air Pollution Study-San Joaquin Valley (CHAPS-SJV): why we study asthma, birth outcomes, air pollution and immunology. Presented via a U.S. EPA Webinar, June 13, 2012. |
R834596 (2012) R834596 (Final) R834596C001 (2012) R834596C002 (2012) R834596C003 (2012) |
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Presentation | Hammond SK. The Children's Health and Air Pollution Study-San Joaquin Valley (CHAPS-SJV): asthma, birth outcomes, air pollution and immunology. Presented at the University of California, Merced, Merced, CA, October 26, 2012. |
R834596 (2012) R834596 (Final) R834596C001 (2012) R834596C002 (2012) R834596C003 (2012) |
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Presentation | Humblet O, Noth EM, Lurmann FW, Pratt B, Hammond SK, Balmes J, Tager I, Nadeau K. Immune function and ambient air pollution exposure in asthmatic children. Poster presented at the International Society for Environmental Epidemiology (ISEE) Annual Meeting, Barcelona, Spain, September 13-16, 2011. |
R834596 (2011) R834596 (2012) R834596 (Final) R834596C003 (2011) R834596C003 (2012) |
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Presentation | Humblet O, Noth EM, Lurmann F, Pratt B, Hammond SK, Balmes J, Tager IB, Nadeau K. Immune function and ambient air pollution exposure in asthmatic children. Poster presented at NIEHS and EPA Centers for Children's Environmental Health and Disease Prevention Research: Strengthening the Network, Bethesda, MD, March 6-7, 2012. |
R834596 (2011) R834596 (2012) R834596 (Final) R834596C003 (2012) |
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Presentation | Humblet O, Padula AM, Nadeau K, Holland N, Balmes I, Tager IB. Lung function growth in asthmatic children in relation to prenatal/early-life second-hand smoke and GSTM1/GSTT1 polymorphisms. Poster presented at the American Thoracic Society International Conference, San Francisco, CA, May 18-23, 2012 (Poster No. A1759). |
R834596 (2011) R834596 (2012) R834596 (Final) R834596C003 (2012) |
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Presentation | Kohli A, Garcia M, Humblet O, Balmes J, Hammond K, Tager I, Nadeau K. Epigenetic changes in IFN-gamma and Foxp3 due to secondhand smoke. Presented at the Children's Environmental Health Network (CEHN) Research Conference, San Francisco, CA, May 30-June 1, 2012. |
R834596 (2012) R834596 (Final) R834596C003 (2012) |
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Presentation | Kohli A, Syed A, Hyman C, Li Z, Sjodin A, Eisen E, Noth E, Pratt B, Hammond K, Nadeau KC. PAH exposures and links to asthma outcomes. Presented at the American Academy of Allergy, Asthma and Immunology (AAAAI) National Meeting, San Antonio, TX, February 22-26, 2013. |
R834596 (2012) R834596 (Final) R834596C003 (2012) |
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Presentation | Liu J, Cachola L, Nadeau KC. Polycyclic aromatic hydrocarbons methylate Foxp3 through the aryl hydrocarbon receptor in Treg. Presented at the American Academy of Allergy, Asthma and Immunology (AAAAI) National Conference, New Orleans, LA, March 18-22, 2011. |
R834596 (2010) R834596 (2011) R834596 (2012) R834596 (Final) R834596C003 (2010) R834596C003 (2011) R834596C003 (2012) |
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Presentation | Liu J, Nadeau KC. Diesel exhaust particles induce conversion of CD4+CD25hiCD127lo regulatory T cells to CD4+CD25neg effector T cells. Presented at the American Thoracic Society International Conference, Denver, CO, May 13-18, 2011. |
R834596 (2010) R834596 (2011) R834596 (2012) R834596 (Final) R834596C003 (2010) R834596C003 (2011) R834596C003 (2012) R834786 (2011) |
not available |
Presentation | Liu J, Winterroth L, Zhang L, Sunwoo J, Hammond SK, Balmes J, Tager IB, Nadeau K. Phenanthrene linked to AhR-mediated Treg instability and Th2 conversion. Poster presented at NIEHS and EPA Centers for Children's Environmental Health and Disease Prevention Research: Strengthening the Network, Bethesda, MD, March 6-7, 2012. |
R834596 (2011) R834596 (2012) R834596 (Final) R834596C003 (2012) |
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Presentation | Mann J, Pratt B, Lurmann F, Reid C, Tager I. Daily changes in air pollution and lung function in the Fresno Asthmatic Children's Environment Study: use of individual-level exposure estimates for air pollutant concentrations. Poster presented at the International Society for Environmental Epidemiology (ISEE) Annual Meeting, Barcelona, Spain, September 13-16, 2011. |
R834596 (2011) R834596 (2012) R834596 (Final) R834596C003 (2012) |
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Presentation | Mann J, Lurmann F, Noth E, Balmes J, Hammond K, Alcorn S, Reid C, Pratt B, Tager IB. Daily changes in air pollution and lung function: use of modeled daily personal exposures. Poster presented at NIEHS and EPA Centers for Children's Environmental Health and Disease Prevention Research: Strengthening the Network, Bethesda, MD, March 6-7, 2012. |
R834596 (2011) R834596 (2012) R834596 (Final) R834596C003 (2012) |
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Presentation | McDonald C, Nadeau K. Ambient air pollution effects on Treg in asthma. Presented at the American Academy of Allergy, Asthma and Immunology (AAAAI) National Conference, New Orleans, LA, February 26-March 2, 2010. |
R834596 (2010) R834596 (2011) R834596 (2012) R834596 (Final) R834596C003 (2010) R834596C003 (2011) R834786 (2011) |
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Presentation | Nadeau K. Ambient air pollution exposure associated with immune dysfunction. Presented at the California Asthma Summit, San Francisco, CA, December 5-6, 2012. |
R834596 (2012) R834596 (Final) R834596C003 (2012) |
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Presentation | Nadeau K. The contribution of epigenetics in pediatric environmental health. Presented at the California Asthma Summit, San Francisco, CA, December 5-6, 2012. |
R834596 (2012) R834596 (Final) R834596C003 (2012) |
not available |
Presentation | Nadeau K. New immune studies to understand the link between air pollution and asthma. Presented via a U.S. EPA Webinar, June 13, 2012. |
R834596 (2012) R834596 (Final) R834596C003 (2012) |
not available |
Presentation | Nadeau K. Mechanistic studies on the link between epigenetic modifications in candidate genes and allergy/asthma. Presented via a U.S. EPA Webinar, May 8, 2013. |
R834596 (2012) R834596 (Final) R834596C003 (2012) |
not available |
Presentation | Padula AM, Humblet O, Mortimer KM, Lurmann F, Tager IB. Exposure to air pollution during pregnancy and pulmonary function growth in the FACES LiTE cohort. Poster presented at the American Thoracic Society International Conference, San Francisco, CA, May 18-23, 2012 (Poster No. 31611). |
R834596 (2011) R834596 (2012) R834596 (Final) R834596C003 (2012) |
not available |
Presentation | Walker A, Hew K, Kohli A, Syed A, Hyman C, Li Z, Sjodin A, Eisen E, Noth E, Pratt B, Balmes J, Hammond SK, Nadeau KC. Childhood exposure to polycyclic aromatic hydrocarbons is associated with impaired systemic immunity and epigenetic modifications in T cell subsets. Presented at the American Academy of Allergy, Asthma and Immunology (AAAAI) National Meeting, San Antonio, TX, February 22-26, 2013. |
R834596 (2012) R834596 (Final) R834596C003 (2012) |
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.