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Abstract (3)
Dissertation/Thesis (1)
Journal Article (6)
Presentation (8)
Proceedings (3)
Reference Type Citation Progress Report Year Document Sources
Abstract Griffin JM, Blossom SJ, Jackson SK, Gilbert KM, Pumford NR. Immunomodulation by trichloroethylene in the autoimmune prone MRL+/+ mice. Toxicological Sciences 1998;42(1-S):7. R826409 (Final)
 not available
Abstract Griffin JM, Gilbert KM, Pumford NR. Cytochrome P450 2E1 metabolism of trichloroethylene accelerates an autoimmune response in MRL+/+ mice. Toxicological Sciences 1999;48(1-S):792. R826409 (Final)
 not available
Abstract Pumford NR. Oxidative stress and endothelial cell damage in autoimmune-prone MRL+/+ mice following trichloroethylene treatment. Toxicological Sciences 2001;60(S-1):206. R826409 (2000)
R826409 (Final)
 not available
Dissertation/Thesis Griffin JM. Acceleration of autoimmunity following exposure to trichloroethylene. Ph.D. Dissertation. University of Arkansas for Medical Sciences, DAI-B 60/12, June 2000, 6063 pp. R826409 (2000)
R826409 (Final)
 not available
Journal Article Gilbert KM, Griffin JM, Pumford NR. Trichloroethylene activates CD4+ T cells: potential role in an autoimmune response. Drug Metabolism Reviews 1999;31(4):901-916. R826409 (1999)
R826409 (Final)
Journal Article Griffin JM, Lipscomb JC, Pumford NR. Covalent binding of trichloroethylene to proteins in human and rat hepatocytes. Toxicology Letters 1998;95(3):173-181. R826409 (Final)
 not available
Journal Article Griffin JM, Gilbert KM, Pumford NR. Inhibition of CYP2E1 reverses CD4+ T cell alterations in trichloroethylene-treated MRL+/+ mice. Toxicological Sciences 2000;54(2):384-389. R826409 (1999)
R826409 (Final)
Journal Article Griffin JM, Gilbert KM, Pumford NR. Cytochrome P450 2E1 metabolism of trichloroethylene accelerates an autoimmune response in MRL+/+ mice. Toxicological Sciences 1999;48(1-S):792 R826409 (Final)
Journal Article Griffin JM, Gilbert KM, Lamps LW, Pumford NR. CD4+ T-cell activation and induction of autoimmune hepatitis following trichloroethylene treatment in MRL+/+ mice. Toxicological Sciences, 2000;57(2):345-352. R826409 (2001)
R826409 (Final)
 not available
Journal Article Griffin JM, Blossom SJ, Jackson SK, Gilbert KM, Pumford NR. Trichloroethylene accelerates an autoimmune response in association with Th1 T-cell activation in MRL+/+ mice. Immunopharmacology, 2000;46(2):123-137. R826409 (1999)
R826409 (Final)
 not available
Presentation Gilbert KM, Whitlow AB, Pumford NR. Environmental contaminant associated with induction of autoimmune disease stimulates T-cells. Presented at the Experimental Biology Meeting, New Orleans, LA, April 20, 2002. R826409 (2001)
R826409 (Final)
 not available
Presentation Griffin JM, Gilbert KM, Pumford NR. Cytochrome P450 activation of trichloroethylene initiates a Th1 T-cell response in MRL+/+ mice. Presented at the Workshop on Linking Environmental Agents and Autoimmune Diseases, National Institutes of Health, National Institute of Environmental Health Sciences, September 1-3, 1998. R826409 (Final)
 not available
Presentation Pumford NR. Chemical-induced immune-mediated hepatotoxicity. Presented at the Workshop on Linking Environmental Agents and Autoimmune Diseases, National Institutes of Health, National Institute of Environmental Health Sciences, September 1-3, 1998. R826409 (Final)
 not available
Presentation Pumford NR. Chlorinated ethylenes and autoimmune disease. Presented at the Pharmaceutical Sciences Graduate Program, Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada, 2001. R826409 (Final)
 not available
Presentation Pumford NR. Immunochemical approaches used to identify and characterize protein adducts associated with xenobiotic-induced toxicities. Presented at the International Society for the Study of Xenobiotics (ISSX) Annual North American Meeting, 1999. R826409 (Final)
 not available
Presentation Pumford NR. Mechanism(s) of chloroethylene-induced autoimmunity. Presented at the U.S. Environmental Protection Agency Science Forum 2002: Meeting the Challenges, Washington, DC, May 1-2, 2002. R826409 (2001)
R826409 (Final)
 not available
Presentation Pumford NR. Oxidative stress and endothelial cell damage in autoimmune-prone MRL+/+ mice following trichloroethylene treatment. Presented at the Annual Meeting of the Society of Toxicology, San Francisco, CA, March 25-29, 2001. R826409 (2000)
 not available
Presentation Pumford NR. Trichloroethylene and autoimmunity. Presented at the Drinking Water and Health Symposium, University of Florida Center for Environmental and Human Health, Superfund Basic Research Program Project, 1999. R826409 (Final)
 not available
Proceedings Pumford NR. Immunochemical approaches used to identify and characterize protein adducts associated with xenobiotic-induced toxicities. In: Proceedings of the invited symposium presentation at the ISSX Annual North American Meeting, Volume 15, October 27, 1999. R826409 (1999)
R826409 (Final)
 not available
Proceedings Pumford NR. Mechanism(s) of chloroethylene-induced autoimmunity. In: Proceedings of the Environmental Protection Agency Science Forum 2002: Meeting the Challenges, May 1-2, 2002, p. 96. R826409 (Final)
 not available
Proceedings Pumford NR. Oxidative stress and endothelial cell damage in autoimmune-prone MRL+/+ mice following trichloroethylene treatment. Presented at the Annual Meeting of the Society of Toxicology, San Francisco, CA, 2001. R826409 (1999)
R826409 (Final)
 not available

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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