Grantee Research Project Results
Selected Publications Details for Grant Number R826409
Mechanism(s) of Chloroethylene-Induced Autoimmunity
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| Reference Type | Citation | Progress Report Year | Document Sources |
|---|---|---|---|
| Journal Article | Gilbert KM, Griffin JM, Pumford NR. Trichloroethylene activates CD4+ T cells: potential role in an autoimmune response. Drug Metabolism Reviews 1999;31(4):901-916. |
R826409 (1999) R826409 (Final) |
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| Journal Article | Griffin JM, Lipscomb JC, Pumford NR. Covalent binding of trichloroethylene to proteins in human and rat hepatocytes. Toxicology Letters 1998;95(3):173-181. |
R826409 (Final) |
not available |
| Journal Article | Griffin JM, Gilbert KM, Pumford NR. Inhibition of CYP2E1 reverses CD4+ T cell alterations in trichloroethylene-treated MRL+/+ mice. Toxicological Sciences 2000;54(2):384-389. |
R826409 (1999) R826409 (Final) |
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| Journal Article | Griffin JM, Gilbert KM, Pumford NR. Cytochrome P450 2E1 metabolism of trichloroethylene accelerates an autoimmune response in MRL+/+ mice. Toxicological Sciences 1999;48(1-S):792 |
R826409 (Final) |
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| Journal Article | Griffin JM, Gilbert KM, Lamps LW, Pumford NR. CD4+ T-cell activation and induction of autoimmune hepatitis following trichloroethylene treatment in MRL+/+ mice. Toxicological Sciences, 2000;57(2):345-352. |
R826409 (2001) R826409 (Final) |
not available |
| Journal Article | Griffin JM, Blossom SJ, Jackson SK, Gilbert KM, Pumford NR. Trichloroethylene accelerates an autoimmune response in association with Th1 T-cell activation in MRL+/+ mice. Immunopharmacology, 2000;46(2):123-137. |
R826409 (1999) R826409 (Final) |
not available |
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