TY - Abstract A1 - Griffin, J M A1 - Blossom, S J A1 - Jackson, S K A1 - Gilbert, K M A1 - Pumford, N R T1 - Immunomodulation by trichloroethylene in the autoimmune prone MRL+/+ mice. Y1 - 1998// N1 - R826409 JF - TOXICOLOGICAL SCIENCES J1 - TOXICOL SCI J2 - Toxicol.Sci. J3 - Toxicological Sciences VL - 42 IS - 1-S SP - 7 ER - TY - Abstract A1 - Griffin, J M A1 - Gilbert, K M A1 - Pumford, N R T1 - Cytochrome P450 2E1 metabolism of trichloroethylene accelerates an autoimmune response in MRL+/+ mice. Y1 - 1999// N1 - R826409 JF - TOXICOLOGICAL SCIENCES J1 - TOXICOL SCI J2 - Toxicol.Sci. J3 - Toxicological Sciences VL - 48 IS - 1-S SP - 792 ER - TY - Abstract A1 - Pumford, N R T1 - Oxidative stress and endothelial cell damage in autoimmune-prone MRL+/+ mice following trichloroethylene treatment. Y1 - 2001// N1 - R826409 JF - TOXICOLOGICAL SCIENCES J1 - TOXICOL SCI J2 - Toxicol.Sci. J3 - Toxicological Sciences VL - 60 IS - S-1 SP - 206 ER - TY - THES A1 - Griffin, J M T1 - Acceleration of autoimmunity following exposure to trichloroethylene. N1 - R826409 ER - TY - JOUR A1 - Gilbert, K M A1 - Griffin, J M A1 - Pumford, N R T1 - Trichloroethylene activates CD4+ T cells: potential role in an autoimmune response. Y1 - 1999// N1 - R826409 JF - DRUG METABOLISM REVIEWS J1 - DRUG METAB REV VL - 31 IS - 4 SP - 901 EP - 916 PB - Dekker ER - TY - JOUR A1 - Griffin, J M A1 - Lipscomb, J C A1 - Pumford, N R T1 - Covalent binding of trichloroethylene to proteins in human and rat hepatocytes. Y1 - 1998// N1 - R826409 JF - TOXICOLOGY LETTERS J1 - TOXICOL LETT VL - 95 IS - 3 SP - 173 EP - 181 ER - TY - JOUR A1 - Griffin, J M A1 - Gilbert, K M A1 - Pumford, N R T1 - Inhibition of CYP2E1 reverses CD4+ T cell alterations in trichloroethylene-treated MRL+/+ mice. Y1 - 2000/04/ N1 - R826409 JF - TOXICOLOGICAL SCIENCES J1 - TOXICOL SCI J2 - Toxicol.Sci. J3 - Toxicological Sciences VL - 54 IS - 2 SP - 384 EP - 389 PB - Oxford Journals ER - TY - JOUR A1 - Griffin, J M A1 - Gilbert, K M A1 - Pumford, N R T1 - Trichloroethylene accelerates an autoimmune response by Th1 T cell activation in MRL+/+ mice Y1 - 2000/02/ N1 - R826409 JF - IMMUNOPHARMACOLOGY J1 - IMMUNOPHARMACOLOGY VL - 46 IS - 2 SP - 123 EP - 37 PB - Oxford Journals ER - TY - JOUR A1 - Griffin, J M A1 - Gilbert, K M A1 - Lamps, L W A1 - Pumford, N R T1 - CD4+ T-cell activation and induction of autoimmune hepatitis following trichloroethylene treatment in MRL+/+ mice. Y1 - 2000// N1 - R826409 JF - TOXICOLOGICAL SCIENCES J1 - TOXICOL SCI J2 - Toxicol.Sci. J3 - Toxicological Sciences VL - 57 IS - 2 SP - 345 EP - 352 ER - TY - JOUR A1 - Griffin, J M A1 - Blossom, S J A1 - Jackson, S K A1 - Gilbert, K M A1 - Pumford, N R T1 - Trichloroethylene accelerates an autoimmune response in association with Th1 T-cell activation in MRL+/+ mice. Y1 - 2000// N1 - R826409 JF - IMMUNOPHARMACOLOGY J1 - IMMUNOPHARMACOLOGY VL - 46 IS - 2 SP - 123 EP - 137 ER - TY - CONF A1 - Gilbert, K M A1 - Whitlow, A B A1 - Pumford, N R T1 - Environmental contaminant associated with induction of autoimmune disease stimulates T-cells. N1 - R826409 ER - TY - CONF A1 - Griffin, J M A1 - Gilbert, K M A1 - Pumford, N R T1 - Cytochrome P450 activation of trichloroethylene initiates a Th1 T-cell response in MRL+/+ mice. N1 - R826409 ER - TY - CONF A1 - Pumford, N R T1 - Chemical-induced immune-mediated hepatotoxicity. N1 - R826409 ER - TY - CONF A1 - Pumford, N R T1 - Chlorinated ethylenes and autoimmune disease. N1 - R826409 ER - TY - CONF A1 - Pumford, N R T1 - Immunochemical approaches used to identify and characterize protein adducts associated with xenobiotic-induced toxicities. N1 - R826409 ER - TY - CONF A1 - Pumford, N R T1 - Mechanism(s) of chloroethylene-induced autoimmunity. N1 - R826409 ER - TY - CONF A1 - Pumford, N R T1 - Oxidative stress and endothelial cell damage in autoimmune-prone MRL+/+ mice following trichloroethylene treatment. N1 - R826409 ER - TY - CONF A1 - Pumford, N R T1 - Trichloroethylene and autoimmunity. N1 - R826409 ER - TY - CONF A1 - Pumford, N R T1 - Immunochemical approaches used to identify and characterize protein adducts associated with xenobiotic-induced toxicities N1 - R826409 ER - TY - CONF A1 - Pumford, N R T1 - Mechanism(s) of chloroethylene-induced autoimmunity. N1 - R826409 ER - TY - CONF A1 - Pumford, N R T1 - Oxidative stress and endothelial cell damage in autoimmune-prone MRL+/+ mice following trichloroethylene treatment N1 - R826409 ER -