Grantee Research Project Results
Publications Details for Grant Number R833137
Risk Assessment of Food Allergenicity by a Data Base Approach
RFA:
Biotechnology: Potential Allergenicity of Genetically Engineered Foods (2006)
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Reference Type | Citation | Progress Report Year | Document Sources |
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Abstract | Bonds RS, Tiwari R, Ning B, Czerwinski EW, Goldblum RM, Midoro-Horiuti T. Cross reactivity in mountain cedar-tomato oral allergy syndrome. Journal of Allergy and Clinical Immunology 2007;119(1):S113 |
R833137 (Final) |
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Abstract | Midoro-Horiuti T, Tiwari R, Negi S, Ning B, Schein C, Braun W, Goldblum R. Analysis for IgE epitopes of Jun a 1 using random peptide display library. Japanese Journal of Allergology 2007;56(8-9):1108. |
R833137 (Final) |
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Journal Article | Bonds RS, Midoro-Horiuti T, Goldblum R. A structural basis for food allergy: the role of cross-reactivity. Current Opinion in Allergy and Clinical Immunology 2008;8(1):82-86. |
R833137 (Final) |
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Journal Article | Fujimura T, Futamura N, Midoro-Horiuti T, Togawa A, Goldblum RM, Yasueda H, Saito A, Shinohara K, Masuda K, Kurata K, Sakaguchi M. Isolation and characterization of native Cry j 3 from Japanese cedar (Cryptomeria japonica) pollen. Allergy 2007;62(5):547-533. |
R833137 (Final) |
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Journal Article | Ivanciuc O, Schein CH, Garcia T, Oezguen N, Negi SS, Braun W. Structural analysis of linear and conformational epitopes of allergens. Regulatory Toxicology and Pharmacology 2009;54(3 Suppl):S11-S19. |
R833137 (2008) R833137 (Final) |
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Journal Article | Ivanciuc O, Garcia T, Torres M, Schein CH, Braun W. Characteristic motifs for families of allergenic proteins. Molecular Immunology 2009;46(4):559-568. |
R833137 (2008) R833137 (Final) |
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Journal Article | Ivanciuc O, Midoro-Horiuti T, Schein CH, Xie L, Hillman GR, Goldblum RM, Braun W. The property distance index PD predicts peptides that cross-react with IgE antibodies. Molecular Immunology 2009;46(5):873-883. |
R833137 (2008) R833137 (Final) |
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Journal Article | Liu Z, Bhattacharyya S, Ning B, Midoro-Horiuti T, Czerwinski EW, Goldblum RM, Mort A, Kearney CM. Plant-expressed recombinant mountain cedar allergen Jun a 1 is allergenic and has limited pectate lyase activity. International Archives of Allergy and Clinical Immunology 2010;153(4):347-358. |
R833137 (Final) |
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Journal Article | Moehnke MH, Midoro-Horiuti T, Goldblum RM, Kearney CM. The expression of a mountain cedar allergen comparing plant-viral apoplastic and yeast expression systems. Biotechnology Letters 2008;30(7):1259-1264. |
R833137 (Final) |
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Journal Article | Negi SS, Braun W. Automated detection of conformational epitopes using phage display peptide sequences. Bioinformatics and Biology Insights 2009;3:71-81. |
R833137 (2008) R833137 (Final) |
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Journal Article | Oezguen N, Zhou B, Negi SS, Ivanciuc O, Schein CH, Labesse G, Braun W. Comprehensive 3D-modeling of allergenic proteins and amino acid composition of potential conformational IgE epitopes. Molecular Immunology 2008;45(14):3740-3747. |
R833137 (2008) R833137 (Final) |
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Journal Article | Schein CH, Ivanciuc O, Braun W. Bioinformatics approaches to classifying allergens and predicting cross-reactivity. Immunology and Allergy Clinics of North America 2007;27(1):1-27. |
R833137 (2007) R833137 (Final) |
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Journal Article | Schein CH, Ivanciuc O, Midoro-Horiuti T, Goldblum RM, Braun W. An allergen portrait gallery: representative structures and an overview of IgE binding surfaces. Bioinformatics and Biology Insights 2010;4:113-125. |
R833137 (Final) R834066 (Final) |
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Journal Article | Tiwari R, Negi SS, Braun B, Braun W, Pomes A, Chapman MD, Goldblum RM, Midoro-Horiuti T. Validation of a phage display and computational algorithm by mapping a conformational epitope of Bla g 2. International Archives of Allergy and Immunology 2012;157(4):323-330. |
R833137 (Final) R834823 (2012) R834823 (2013) R834823 (Final) |
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Journal Article | Varshney S, Goldblum RM, Kearney C, Watanabe M, Midoro-Horiuti T. Major mountain cedar allergen, Jun a 1 contains conformational as well as linear IgE epitopes. Molecular Immunology 2007;44(10):2781-2785. |
R833137 (Final) |
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Presentation | Braun W. The structural biology of allergens. Presented at the Oesper Symposium 2010 honoring Kurt Wuethrich (Nobel Prize 2002 in Chemistry), University of Cincinnati, Cincinnati, OH, October 8, 2010. |
R833137 (Final) R834823 (2011) R834823 (Final) |
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Presentation | Braun W. Allergen structures in a genomics age. Presented at the Keystone Symposium: Structural Genomics: Expanding the Horizons of Structural Biology, Beaver Run Resort, Breckenridge, CO, January 10, 2010. |
R833137 (Final) |
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Presentation | Braun W. Prediction and detection of conformational epitopes of IgE antibodies. Presented at the 48th Annual Meeting of the Society of Toxicology, Baltimore, MD, March 15-19, 2009. |
R833137 (Final) |
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Presentation | Braun W, Goldblum RM, Schein CH, Midoro-Horiuti T, Gendel S. Risk assessment of food allergenicity by a data base approach. Presented at the Health and Environmental Sciences Institute's (HESI) Research to Improve Safety Assessment of Biotechnology Products for Potential Risk of Food Allergy Meeting, Washington, DC, October 15-16, 2008. |
R833137 (2008) R833137 (Final) |
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Presentation | Braun W. Structural (3-D) comparisons of novel proteins to known allergens. Presented at the Protein Allergenicity Technical Committee New Methods Workshop, ILSI Health and Environmental Sciences Institute (HESI), Nice, France October 24, 2007. |
R833137 (Final) |
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Presentation | Chattopadhyay A, Ivanciuc O, Negi SS, Braun W. Computational analysis of allergenic determinants for the peanut allergen Ara h 3. Presented at the 14th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, The University of Texas Medical Branch, Galveston, TX, March 27, 2009. |
R833137 (Final) |
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Presentation | Esadze A, Ivanciuc O, Braun W. Comparative study of IgE epitopes and sequence conservation in the melon allergen Cuc m 2. Presented at the 15th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, Hotel Galvez, Galveston, TX, March 19, 2010. |
R833137 (Final) |
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Presentation | Han W, Ivanciuc O, Oezguen N, Braun W. Development of an automated process for homology based prediction of protein 3D structure. Poster presented at the 2010 Medical Student Summer Research Program Poster Session, University of Texas Medical Branch, Galveston, TX, June 24, 2010. |
R833137 (Final) |
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Presentation | Ivanciuc OI, Midoro-Horiuti T, Schein CH, Goldblum RM, Braun W. Application of the Property Distance Index PD for the computer-aided design of IgE binding peptides for the allergen Jun a 1. Presented at the 12th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, University of Texas Medical Branch Galveston, Galveston, TX, May 18-19, 2007. |
R833137 (Final) |
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Presentation | Ivanciuc O, Power TD, Gendel SM, Schein CH, Braun W. AllerML: ontology and markup language for allergens and for structural biology studies of allergenicity. Presented at the 13th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, University of Texas Medical Branch, Galveston, TX, May 16-17, 2008. |
R833137 (Final) |
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Presentation | Ivanciuc O, Midoro-Horiuti T, Schein CH, Goldblum RM, Braun W. Machine learning for peptide cross-reactivity with the mountain cedar allergen Jun a 1. Presented at the 15th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, Hotel Galvez, Galveston, TX, March 19, 2010. |
R833137 (Final) |
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Presentation | Lu W, Braun W. A new method to evaluate and combine 3D templates for homology modeling. Presented at the 15th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, Hotel Galvez, Galveston, TX, March 19, 2010. |
R833137 (Final) |
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Presentation | Midoro-Horiuti T, Ning B, Goldblum RM. Development of new immunomodulatory agents for cedar pollen allergy. Presented at the Annual Meeting of the American College of Allergy, Asthma and Immunology, Miami, FL, November 4-8, 2009. |
R833137 (Final) |
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Presentation | Midoro-Horiuti T, Tiwari R, Negi SS, Schein CH, Ning B, Goldblum RM, Braun W. Use of random peptide display and novel bioinformatics algorithm to detect conformational epitopes of Jun a 1, the major allergen of mountain cedar pollen. Presented at the Federation of Clinical Immunology Societies (FOCIS) Meeting, San Diego, CA, June 7-11, 2007. |
R833137 (Final) |
not available |
Presentation | Midoro-Horiuti T, Tiwari R, Negi S, Ning B, Schein C, Braun W, Goldblum R. Use of random peptide display and novel bioinformatics algorithm to detect conformational epitopes of Jun a 1, the major allergen of mountain cedar pollen. Presented at the American Society for Clinical Investigation/Association of American Physicians Joint Meeting, Chicago, IL, April 13-15, 2007. |
R833137 (Final) |
not available |
Presentation | Negi SS, Braun W. Mapping conformational epitopes on protein surfaces using phage display libraries. Presented at the 12th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, University of Texas Medical Branch Galveston, Galveston, TX, May 18-19, 2007. |
R833137 (Final) |
not available |
Presentation | Negi SS, Tiwari R, Midoro-Horiuti T, Goldblum RA, Braun W. EpiSearch: a new method for mapping conformational epitopes using peptide mimics from phage display libraries. Presented at the 14th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, The University of Texas Medical Branch Galveston, Galveston, TX, March 27, 2009. |
R833137 (Final) |
not available |
Presentation | Negi SS, Oezguen N, Braun W. Prediction of allergen cross-reactivity using structural bioinformatics methods. Presented at the 15th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, Hotel Galvez, Galveston, TX, March 19, 2010. |
R833137 (Final) |
not available |
Presentation | Negi S, Tiwari R, Midoro-Horiuti T, Goldblum RM, Braun W. EpiSearch: a new method for mapping conformational epitopes using peptide mimics from phage display libraries. Presented at the 13th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, University of Texas Medical Branch Galveston, Galveston, TX, May 16-17, 2008. |
R833137 (Final) |
not available |
Presentation | Oezguen N, Zhou B, Negi SS, Ivanciuc OI, Braun W. Homology modeling of allergenic proteins and surface analysis of known epitopes. Presented at the 12th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, University of Texas Medical Branch Galveston, Galveston, TX, May 18-19, 2007. |
R833137 (Final) |
not available |
Presentation | Saito A, Braun BA, Ning B, Midoro-Horiuti T, Goldblum RM. Identifying conformational epitope of cedar pollen allergen (Jun a 1). Presented at the Summer Undergraduate Research Program, University of Texas Medical Branch Galveston, Galveston, TX, August 14, 2009. |
R833137 (Final) |
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Presentation | Schein CH. Common allergenic epitopes in nut proteins contribute to cross reactivity. Presented at the ILSI Health and Environmental Sciences Institute (HESI) Food Allergy Workshop, The Beacon Hotel and Corporate Quarters, Washington, DC, October 15, 2008. |
R833137 (Final) R834066 (2010) R834066 (Final) |
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Presentation | Schein CH. Defining IgE epitopes involved in allergen cross reactivity. Presented at the UTMB Immunology Research in Progress Seminar, The University of Texas Medical Branch Galveston, Galveston, TX, April 1, 2009. |
R833137 (Final) R834066 (2010) R834066 (Final) |
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Presentation | Schein CH, Maleki SJ, Teuber S. Identifying similar IgE-epitopes in peanut and walnut allergens. Presented at the American Academy of Allergy, Asthma & Immunology (AAAAI) Annual Meeting, New Orleans, LA, February 26-March 2, 2010. |
R833137 (Final) R834066 (2010) R834066 (Final) |
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Presentation | Schein CH, Maleki S, Teuber S. Using physicochemical-property similarity to define common IgE-epitopes in peanut and walnut allergens. Presented at the 15th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, Hotel Galvez, Galveston, TX, March 19, 2010. |
R833137 (Final) R834066 (2010) R834066 (Final) |
not available |
Presentation | Schein CH, Ivanciuc O, Midoro-Horiuti T, Xie L, Hillman GR, Goldblum RM, Braun W. Identification of Jun a 1 cross-reactive peptides using physico-chemical indices and partial least squares. Presented at the 13th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, University of Texas Medical Branch Galveston, Galveston, TX May 16-17, 2008. |
R833137 (Final) |
not available |
Presentation | Tiwari R, Ning B, Negi S, Endsley M, Estes D, Schein C, Braun W, Midoro-Horiuti T, Goldblum R. Mapping conformational epitopes on Jun a 1, the major allergen of mountain cedar pollen. Presented at the Annual Meeting of American Academy of Allergy, Asthma and Immunology, San Diego, CA, February 23-27, 2007. |
R833137 (Final) |
not available |
Presentation | Tiwari R, Ning B, Negi SS, Endsley M, Estes D, Schein CH, Braun W, Midoro-Horiuti T, Goldblum R. Mapping conformational epitopes on Jun a 1, the major allergen of mountain cedar pollen. Presented at the 12th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, University of Texas Medical Branch Galveston, Galveston, TX, May 18-19, 2007. |
R833137 (Final) |
not available |
Presentation | Tiwari R, Negi S, Midoro-Horiuti T, Pomes A, Chapman MD, Braun W, Goldblum RM. Validation of phage display and computational algorithms for mapping conformational epitopes. Presented at the Annual Meeting of American Academy of Allergy, Asthma and Immunology, Philadelphia, PA, March 14-18, 2008. |
R833137 (Final) |
not available |
Presentation | Braun W, Goldblum RM, Schein CH, Midoro-Horiuti T, Gendel S. Risk assessment of food allergenicity by a data base approach. Presented at the Second Symposium for Agricultural Biotechnology Risk Analysis Research organized by the AGRA Task Group, College Park, MD, December 5-6, 2007. |
R833137 (2008) |
not available |
Working Group/Panel | Braun W. Participation in the FIFRA Scientific Advisory Panel of the U.S. EPA, EPA Conference Center, Arlington, VA, February 25-27, 2009. |
R833137 (Final) |
not available |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.