Grantee Research Project Results
Journal Publications Details for Grant Number CR830686
Species-Specific Xenobiotic Metabolism Mediated by the Steroid and Xenobiotic Receptor SXR
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Reference Type | Citation | Progress Report Year | Document Sources |
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Journal Article | Grun F, Watanabe H, Zamanian Z, Maeda L, Arima K, Cubacha R, Gardiner DM, Kanno J, Iguchi T, Blumberg B. Endocrine-disrupting organotin compounds are potent inducers of adipogenesis in vertebrates. Molecular Endocrinology 2006;20(9):2141-2155. |
CR830686 (2006) |
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Journal Article | Grun F, Blumberg B. Environmental obesogens: organotins and endocrine disruption via nuclear receptor signaling. Endocrinology 2006;147(6):S50-S55. |
CR830686 (2006) |
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Journal Article | Gunderson MP, Kohno S, Blumberg B, Iguchi T, Guillette Jr LJ. Up-regulation of the alligator CYP3A77 gene by toxaphene and dexamethasone and its short term effect on plasma testosterone concentrations. Aquatic Toxicology 2006;78(3):272-283. |
CR830686 (2006) |
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Journal Article | Tabb MM, Kholodovych V, Grün F, Zhou C, Welsh WJ, Blumberg B. Highly chlorinated PCBs inhibit the human xenobiotic response mediated by the steroid and xenobiotic receptor (SXR). Environmental Health Perspectives 2004;112(2):163-169. |
CR830686 (2003) CR830686 (2006) R826133 (Final) |
not available |
Journal Article | Tabb MM, Blumberg B. New modes of action for endocrine-disrupting chemicals. Molecular Endocrinology 2006;20(3):475-482. |
CR830686 (2006) |
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Journal Article | Zhou C, Tabb MM, Sadatrafiei A, Grün F, Blumberg B. Tocotrienols activate the steroid and xenobiotic receptor, SXR, and selectively regulate expression of its target genes. Drug Metabolism and Disposition 2004;32(10):1075-1082. |
CR830686 (2004) CR830686 (2006) |
not available |
Journal Article | Zhou C, Tabb MM, Nelson EL, Grun F, Verma S, Sadatrafiei A, Lin M, Mallick S, Forman BM, Thummel KE, Blumberg B. Mutual repression between steroid and xenobiotic receptor and NF-κB signaling pathways links xenobiotic metabolism and inflammation. The Journal of Clinical Investigation 2006b;116(8):2280-2289. |
CR830686 (2006) |
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Journal Article | Zhou C, Assem M, Tay JC, Watkins PB, Blumberg B, Schuetz EG, Thummel KE. Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia. The Journal of Clinical Investigation 2006a;116(6):1703-1712. |
CR830686 (2006) |
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