Grantee Research Project Results
Journal Publications Details for Grant Number R839505
Multiplexed human BrainSphere Developmental Neurotoxicity Test for Six Key Events of Neural Development
RFA:
Advancing Actionable Alternatives to Vertebrate Animal Testing for Chemical Safety Assessment (2018)
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Reference Type | Citation | Progress Report Year | Document Sources |
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Journal Article | Modafferi S, Zhong X, Kleensang A, Murata Y, Fagiani F, Pamies D, Hogberg HT, Calabrese V, Lachman H, Hartung T, Smirnova L. Gene–Environment Interactions in Developmental Neurotoxicity:a Case Study of Synergy between Chlorpyrifos and CHD8 Knockout in Human BrainSpheres. Environmental Health Perspectives 2021;129(7):077001. |
R839505 (2021) |
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Journal Article | Chesnut M, Paschoud H, Repoind C, Smirnova L, Hartung T, Zurich MG, Hogberg HT, Pamies D. Human IPSC-Derived Model to Study Myelin Disruption. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021;22(17):9473. |
R839505 (2020) |
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Journal Article | Pistollato F, Bal-Price A, Coecke S, Parvatam S, Pamies D, Czysz K, Hao J, Kee K, Teo AK, Niu S, Wilmes A. Quality criteria for in vitro human pluripotent stem cell-derived models of tissue-based cells. Reproductive Toxicology 2022;112:36-50. |
R839505 (2022) |
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Journal Article | Huang Q, Tang B, Romero JC, Yang Y, Elsayed SK, Pahapale G, Lee TJ, Morales Pantoja IE, Han F, Berlinicke C, Xiang T. Shell microelectrode arrays (MEAs) for brain organoids. Science advances 2022;8(33):eabq5031. |
R839505 (2022) |
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Journal Article | Hogberg HT, Smirnova L. The future of 3D brain cultures in developmental neurotoxicity testing. Frontiers in Toxicology 2022;4:808620. |
R839505 (2022) |
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Journal Article | Romero JC, Berlinicke C, Chow S, Duan Y, Wang Y, Chamling X, Smirnova L. Oligodendrogenesis and myelination tracing in a CRISPR/Cas9-engineered brain microphysiological system. Frontiers in Cellular Neuroscience 2023;16:1094291. |
R839505 (2023) |
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Journal Article | Morales Pantoja IE, Ding L, Leite PE, Marques SA, Romero JC, Alam El Din DM, Zack DJ, Chamling X, Smirnova L. A Novel Approach to Increase Glial Cell Populations in Brain Microphysiological Systems. Advanced Biology 2023:2300198. |
R839505 (2023) |
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Journal Article | Smirnova L, Caffo BS, Gracias DH, Huang Q, Morales Pantoja IE, Tang B, Zack DJ, Berlinicke CA, Boyd JL, Harris TD, Johnson EC. Organoid intelligence (OI):the new frontier in biocomputing and intelligence-in-a-dish. Frontiers in Science 2023:0. |
R839505 (2023) |
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Journal Article | Smirnova L, Stacey GN. Progress in human stem cell-derived models for developmental and reproductive toxicology studies. Reproductive toxicology 2022:S0890-6238. |
R839505 (2022) |
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