Grantee Research Project Results
2010 Progress Report: Project B: Exposure Project: Mn, DDT/E and PBDE Exposure to Farmworker Children
EPA Grant Number: R834513C002Subproject: this is subproject number 002 , established and managed by the Center Director under grant R834513
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
Center: Center for Research on Early Childhood Exposure and Development in Puerto Rico
Center Director: Alshawabkeh, Akram
Title: Project B: Exposure Project: Mn, DDT/E and PBDE Exposure to Farmworker Children
Investigators: Eskenazi, Brenda , Bradman, Asa
Current Investigators: Eskenazi, Brenda , Harley, Kim , Holland, Nina T. , Jerrett, Michael , Sjodin, Andreas , Arora, Manish , Smith, Donald , Eisen, Ellen , Molitor, John , Hubbard, Alan , Lustig, Robert
Institution: University of California - Berkeley
EPA Project Officer: Hahn, Intaek
Project Period: August 1, 2009 through July 31, 2014 (Extended to July 31, 2017)
Project Period Covered by this Report: August 1, 2010 through May 31,2011
RFA: Children's Environmental Health and Disease Prevention Research Centers (with NIEHS) (2009) RFA Text | Recipients Lists
Research Category: Children's Health , Human Health
Objective:
- To measure Mn, PBDEs and DDT/E in shed deciduous teeth (Population: CHAMACOS children participating since birth).
- To determine the relationship between Mn, PBDE and DDT/E levels in teeth with other relevant biological measures.
- To quantify the contribution of agricultural pesticide use to Mn levels in house dust, teeth and child blood.
- To identify population correlates of PBDEs and DDT/E exposure in 9-year-old boys.
Progress Summary:
Note: This report covers the project period 8/1/2010-5/31/2011
- DAPS in child urine. We recently published an article describing organophosphate (OP) pesticide metabolite dialkyl phosphate (DAP) levels in CHAMACOS children at 6, 12 and 24 months.
- DAPs in the environment (EPA STAR Fellowship): Measurements of DAPs in urine may come from OP pesticide in child or intake of preformed DAPs. We measured preformed DAPs in dust. DAPs were present in dust but did not significantly contribute to measured DAPs in urine. A second manuscript is in review.
- PBDEs in Pregnant women and children (NIEHS): An article we recently published in Environmental Health Perspectives showed that PBDE levels in CHAMACOS children were seven times higher than similar children living in Mexico, and three times higher than levels in their mothers. The higher exposures were likely related to the use of chemical flame retardants to meet unique California flammability laws.
Future Activities:
Journal Articles on this Report : 11 Displayed | Download in RIS Format
Other subproject views: | All 108 publications | 43 publications in selected types | All 42 journal articles |
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Other center views: | All 694 publications | 167 publications in selected types | All 166 journal articles |
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Bradman A, Castorina R, Goldman Rosas L, Fenster L, Marks A, Sjodin A, Harley K, Holland N, Eskenazi B. Polybrominated diphenyl ether (PBDE) exposure among Mexican children and Mexican-American children in the CHAMACOS cohort and NHANES. Epidemiology 2011;22(1):S148. |
R834513 (2010) R834513 (2011) R834513 (2012) R834513 (2013) R834513 (2015) R834513 (2016) R834513 (Final) R834513C001 (2010) R834513C001 (2011) R834513C002 (2010) R834513C002 (2011) R834513C002 (2012) |
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Castorina R, Bradman A, Fenster L, Sjodin A, Jones R, Eisen E, Harley K, Holland N, Eskenazi B. Predictors of serum polybrominated diphenyl ether (PBDE) exposure among pregnant women living in California, and comparison of maternal and child levels. Epidemiology 2011;22(1):S81. |
R834513 (2010) R834513 (2011) R834513 (2012) R834513 (2013) R834513 (2015) R834513 (2016) R834513 (Final) R834513C001 (2010) R834513C001 (2011) R834513C002 (2010) R834513C002 (2011) R834513C002 (2012) R834513C003 (Final) |
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Bradman A, Castorina R, Barr DB, Chevrier J, Harnly ME, Eisen EA, McKone TE, Harley K, Holland N, Eskenazi B. Determinants of organophosphorus pesticide urinary metabolite levels in young children living in an agricultural community. International Journal of Environmental Research and Public Health 2011;8(4):1061-1083. |
R834513 (2010) R834513 (2011) R834513 (2012) R834513 (2013) R834513 (2015) R834513 (2016) R834513 (Final) R834513C001 (2010) R834513C001 (2011) R834513C002 (2010) R834513C002 (2011) R834513C002 (2012) R834513C003 (2010) R834513C003 (2011) R834513C003 (Final) R831710 (Final) R832734 (Final) |
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Castorina R, Bradman A, Fenster L, Barr DB, Bravo R, Vedar MG, Harnly ME, McKone TE, Eisen EA, Eskenazi B. Comparison of current-use pesticide and other toxicant urinary metabolite levels among pregnant women in the CHAMACOS cohort and NHANES. Environmental Health Perspectives 2010;118(6):856-863. |
R834513 (2010) R834513 (2011) R834513 (Final) R834513C002 (2010) R834513C002 (2011) R834513C003 (Final) R831710 (Final) |
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Castorina R, Bradman A, Sjodin A, Fenster L, Jones RS, Harley KG, Eisen EA, Eskenazi B. Determinants of serum polybrominated diphenyl ether (PBDE) levels among pregnant women in the CHAMACOS cohort. Environmental Science & Technology 2011;45(15):6553-6560. |
R834513 (2010) R834513 (2011) R834513 (2012) R834513 (2013) R834513 (2015) R834513 (2016) R834513 (Final) R834513C001 (2010) R834513C001 (2011) R834513C001 (2012) R834513C002 (2010) R834513C002 (2011) R834513C002 (2012) R834513C003 (2012) R834513C003 (Final) R831710 (Final) |
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Eskenazi B, Fenster L, Castorina R, Marks AR, Sjodin A, Rosas LG, Holland N, Guerra AG, Lopez-Carrillo L, Bradman A. A comparison of PBDE serum concentrations in Mexican and Mexican-American children living in California. Environmental Health Perspectives 2011;119(10):1442-1448. |
R834513 (2010) R834513 (2011) R834513 (2012) R834513 (2013) R834513 (2015) R834513 (2016) R834513 (Final) R834513C001 (2010) R834513C001 (2011) R834513C001 (2012) R834513C002 (2010) R834513C002 (2011) R834513C002 (2012) R834513C003 (2010) R834513C003 (2011) R831710 (Final) |
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Gunier RB, Jerrett M, Smith DR, Jursa T, Yousefi P, Camacho J, Hubbard A, Eskenazi B, Bradman A. Determinants of manganese levels in house dust samples from the CHAMACOS cohort. Science of the Total Environment 2014;497-498:360-368. |
R834513 (2012) R834513 (2013) R834513 (2014) R834513 (2015) R834513 (Final) R834513C002 (2010) R834513C002 (2012) R834513C002 (2014) R834513C002 (2015) |
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Huen K, Bradman A, Harley K, Yousefi P, Boyd Barr D, Eskenazi B, Holland N. Organophosphate pesticide levels in blood and urine of women and newborns living in an agricultural community. Environmental Research 2012;117:8-16. |
R834513 (2010) R834513 (2011) R834513 (2012) R834513 (2013) R834513 (2015) R834513 (2016) R834513 (Final) R834513C001 (2010) R834513C001 (2011) R834513C002 (2010) R834513C002 (2012) R834513C002 (2013) R834513C003 (2010) R834513C003 (2011) R834513C003 (2012) R831710 (Final) R832734 (Final) |
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Quiros-Alcala L, Bradman A, Nishioka M, Harnly ME, Hubbard A, McKone TE, Eskenazi B. Concentrations and loadings of polybrominated diphenyl ethers in dust from low-income households in California. Environment International 2011;37(3):592-596. |
R834513 (2010) R834513 (2011) R834513 (2012) R834513 (2013) R834513 (2015) R834513 (2016) R834513C001 (2010) R834513C001 (2011) R834513C002 (2010) R834513C002 (2011) R834513C002 (2012) R831710 (Final) |
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Quiros-Alcala L, Bradman A, Nishioka M, Harnly ME, Hubbard A, McKone TE, Ferber J, Eskenazi B. Pesticides in house dust from urban and farmworker households in California: an observational measurement study. Environmental Health 2011;10:19 (15 pp.). |
R834513 (2010) R834513 (2011) R834513 (2012) R834513 (2013) R834513 (2015) R834513 (2016) R834513 (Final) R834513C001 (2010) R834513C001 (2011) R834513C002 (2010) R834513C002 (2011) R834513C002 (2012) R831710 (Final) |
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Weldon RH, Webster M, Harley KG, Bradman A, Fenster L, Davis MD, Hubbard A, Barr DB, Holland N, Eskenazi B. Serum persistent organic pollutants and duration of lactation among Mexican-American women. Journal of Environmental and Public Health 2010;2010:861757 (11 pp.). |
R834513 (2010) R834513 (2011) R834513 (2012) R834513 (2013) R834513 (2015) R834513 (2016) R834513 (Final) R834513C001 (2010) R834513C001 (2011) R834513C002 (2010) R834513C002 (2011) R834513C003 (2010) R834513C003 (2011) R831710 (Final) |
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Supplemental Keywords:
RFA, Health, Scientific Discipline, INTERNATIONAL COOPERATION, Health Risk Assessment, Children's Health, Environmental Policy, Biology, farmworkers, pesticide exposure, flame retardants, PBDE, children's vulnerablity, neurochemical effects, harmful environmental agents, biological markers, agricultural communityRelevant Websites:
Center for Environmental Research and Children's Health Exit
Progress and Final Reports:
Original AbstractMain Center Abstract and Reports:
R834513 Center for Research on Early Childhood Exposure and Development in Puerto Rico Subprojects under this Center: (EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
R834513C001 CHAMACOS Cohort Project: Pesticides and PBDE on Neurobehavior and Puberty
R834513C002 Project B: Exposure Project: Mn, DDT/E and PBDE Exposure to Farmworker Children
R834513C003 Epigenetics Project
R834513C004 Community Outreach and Translation Core
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.
Project Research Results
- Final Report
- 2016 Progress Report
- 2015 Progress Report
- 2014 Progress Report
- 2013 Progress Report
- 2012 Progress Report
- 2011 Progress Report
- Original Abstract
42 journal articles for this subproject
Main Center: R834513
694 publications for this center
166 journal articles for this center