Grantee Research Project Results
Final Report: Toxicity of Drinking Water Associated with Alternative Distribution System Rehabilitation Strategies
EPA Grant Number: R834867Title: Toxicity of Drinking Water Associated with Alternative Distribution System Rehabilitation Strategies
Investigators: Mariñas, Benito J. , Plewa, Michael J.
Institution: University of Illinois Urbana-Champaign
EPA Project Officer: Page, Angela
Project Period: June 1, 2011 through May 31, 2015
Project Amount: $599,113
RFA: Advancing Public Health Protection through Water Infrastructure Sustainability (2009) RFA Text | Recipients Lists
Research Category: Drinking Water , Water
Objective:
Investigate the potential impact on public health brought about by emerging alternatives for rehabilitating drinking water distribution systems.
Summary/Accomplishments (Outputs/Outcomes):
The research conducted in U.S. EPA STAR Grant R834867 generated three themes related to environmental and public health concerns involving drinking water. These themes were (i) identifying the toxicity, and mechanisms of toxicity of specific classes of DBPs, (ii) the impact of Br⁻/I⁻ on toxicity, and (iii) identifying the DBP forcing agents for toxicity in drinking water. Theme (i) presented comprehensive mechanisms for the adverse biological effects by regulated and emerging DBPs. Theme (ii) directly connected DBP formation chemistry mediated by Br− and I− with mammalian cell toxicity for the first time. Theme (iii) provided insights on those chemical classes driving the toxicity of the finished drinking water. All themes will aid understanding DBP toxicity and the outcome of this project will lead to DBP control strategies in drinking water to better protect public health.
Journal Articles on this Report : 5 Displayed | Download in RIS Format
| Other project views: | All 9 publications | 7 publications in selected types | All 6 journal articles |
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Dad A, Jeong CH, Wagner ED, Plewa MJ. Haloacetic Acid Water Disinfection Byproducts Affect Pyruvate Dehydrogenase Activity and Disrupt Cellular Metabolism. Environmental Science & Technology2018;52(3):1525-1532. |
R834867 (Final) |
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Gustafson R, Hiibel S, Childress A. Membrane distillation driven by intermittent and variable-temperature waste heat:System arrangements for water production and heat storage. DESALINATION 2018;448:49-59. |
R834867 (Final) |
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Gustafson R, McGaughey A, Ding W, McVety S, Childress A. Morphological changes and creep recovery behavior of expanded polytetrafluoroethylene (ePTFE) membranes used for membrane distillation. JOURNAL OF MEMBRANE SCIENCE 2019;584:236-245. |
R834867 (Final) |
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Jeong CH, Postigo C, Richardson SD, Simmons JE, Kimura SY, Marinas BJ, Barcelo D, Liang P, Wagner ED, Plewa MJ. Occurrence and comparative toxicity of haloacetaldehyde disinfection byproducts in drinking water. Environmental.Science & Technology 2015;49(23):13749-13759. |
R834867 (Final) |
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Komaki Y, Marinas BJ, Plewa MJ. Toxicity of drinking water disinfection byproducts: cell cycle alterations induced by the monohaloacetonitriles. Environmental Science & Technology 2014;48(19):11662-11669. |
R834867 (2013) R834867 (Final) |
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Progress and Final Reports:
Original AbstractThe perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.