Grantee Research Project Results

Perinatal PCB Exposure and Neuropsychological/Auditory Function

EPA Grant Number: R829390C002
Subproject: this is subproject number 002 , established and managed by the Center Director under grant R829390
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
Center: Organotypic Culture Models For Predictive Toxicology Center
Center Director: Rusyn, Ivan
Title: Perinatal PCB Exposure and Neuropsychological/Auditory Function
Investigators: Sweeney, Anne , Symanski, Elaine , Schantz, Susan L. , Peck, Jennifer , Gardiner, Joseph , Persky, Vicky
Current Investigators: Sweeney, Anne , Schantz, Susan L. , Peck, Jennifer , Persky, Vicky
Institution: The University of Texas at Houston , Texas A & M University , Michigan State University , University of Illinois Urbana-Champaign
Current Institution: Texas A & M University , The University of Texas at Houston , University of Illinois Urbana-Champaign
EPA Project Officer: Aja, Hayley
Project Period: October 17, 2001 through October 16, 2002
RFA: Centers for Children's Environmental Health and Disease Prevention Research (2001) RFA Text | Recipients Lists
Research Category: Human Health , Children's Health

Objective:

This study will examine the patterns of PCB and methylmercury (MeHg) exposures (occurring through consumption of contaminated sport-caught fish) during gestation and their effects on neuropsychological and auditory function among the children born to a cohort of Hmong and Laotian women.

Publications and Presentations:

Publications have been submitted on this subproject: View all 5 publications for this subproject | View all 40 publications for this center

Journal Articles:

Journal Articles have been submitted on this subproject: View all 3 journal articles for this subproject | View all 23 journal articles for this center

Supplemental Keywords:

PCBs, MeHg, thyroid hormones, neuropsychological function, auditory function, in utero exposure., RFA, Scientific Discipline, Health, PHYSICAL ASPECTS, ENVIRONMENTAL MANAGEMENT, Toxicology, Health Risk Assessment, Risk Assessments, Susceptibility/Sensitive Population/Genetic Susceptibility, Physical Processes, Children's Health, genetic susceptability, Molecular Biology/Genetics, Risk Assessment, sensitive populations, neurotoxic, developmental neurotoxicology, biomarkers, childhood cancer, exposure, animal model, developmental effects, perinatal exposure, children, Human Health Risk Assessment, human exposure, methylmercury, residential populations, PCB, children's vulnerablity, assessment of exposure, neurodevelopmental toxicity, neurobehavioral effects, auditory function, biological markers, toxics, neurological development

Progress and Final Reports:

Final

Main Center Abstract and Reports:

R829390 Organotypic Culture Models For Predictive Toxicology Center

Subprojects under this Center: (EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
R829390C001 Neurobehavioral Effects of PCBs and Methylmercury in Rats
R829390C002 Perinatal PCB Exposure and Neuropsychological/Auditory Function
R829390C003 FRIENDS Analytical Toxicology Core Facility
R829390C004 Developmental Effects of PCBs and Methylmercury

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.