Science Inventory

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Wittwehr, C., X. Chang, W. Bisson, S. Edwards, S. Ferguson, A. Harrill, H. Hogberg, A. Karmaus, S. Batista-Leite, E. Lekka, N. Kleinstreuer, K. Markey, A. Masci, M. Mennecozzi, H. Mortensen, J. O'Brien, E. Reinke, C. Schmitt, N. Tucker, AND V. Virvilis. Methods2AOP: An International Collaboration to Integrate Assay Annotations into the AOP Key Event Descriptions. Society of Toxicology 62nd Annual Meeting and ToxExpo 2023, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.23564160

Wittwehr, C., L. Clerbaux, S. Edwards, M. Angrish, H. Mortensen, A. Carusi, M. Gromelski, E. Lekka, V. Virvilis, M. Martens, L. Bonino, AND P. Nymark. Why Adverse Outcome Pathways Need to be FAIR. ALTEX. Society ALTEX Edition, Kuesnacht, Switzerland, 40:#, (2023). https://doi.org/10.14573/altex.2307131

Boyes, W., B. Beach, L. Thornton, P. Harten, H. Mortensen, AND G. Chan. An EPA database on the effects of engineered nanomaterials - NaKnowBase . Scientific Data. Springer Nature, New York, NY, 9(12):1, (2022). https://doi.org/10.1038/s41597-021-01098-0

Mortensen, H., S. Mayasich, Liang Merlin Mei, L. Clerbaux, N. Amigó, M. Amorim, A. Bal-Price, S. Batista Leite, A. Beronius, G. Bezemer, A. Bostroem, A. Carusi, S. Coecke, R. Concha, E. Daskalopoulos, F. Debernardi, E. Edrosa, S. Edwards, J. Filipovska, N. Garcia-Reyero, F. Gavins, S. Halappanavar, A. Hargreaves, H. Hogberg, M. Huynh, D. Jacobson, J. Josephs-Spaulding, Y. Kim, H. Kong, C. Krebs, A. Lam, B. Landesmann, A. Layton, Y. Oh Lee, D. Macmillan, A. Mantovani, L. Margiotta-Casaluci, M. Martens, R. Masereeuw, S. Sally A. Mayasich, A. Munoz, P. Nymark, E. Ohayon, J. Ojasi, A. Paini, N. Parissis, S. Parvatam, F. Pistollato, M. Sachana, J. Birkelund Sørli, K. Sullivan, J. Sund, S. Tanabe, K. Tsaioun, AND M. Vinken. COVID-19 through adverse outcome pathways: Building networks to better understand the disease – 3rd CIAO AOP Design Workshop. ALTEX. Society ALTEX Edition, Kuesnacht, Switzerland, 39(2):332-335, (2022). https://doi.org/10.14573/altex.2112161

Mei, Liang Merlin, M. Mei, M. Martens, D. Jacobson, J. Waspe, S. Halappanavar, P. Nymark, AND H. Mortensen. Development of a Hub Adverse Outcome Pathway for Hyperinflammation. Society of Advancement of Adverse Outcome Pathways (AAOP), RTP, NC, February 15 - 22, 2022.

Mortensen, H., M. Martens, J. Senn, T. Levey, C. Evelo, E. Willighagan, AND T. Exner. The AOP-DB RDF: Applying FAIR Principles to the Semantic Integration of AOP Data Integration using the Research Description Framework. Frontiers in Toxicology. Frontiers, Lausanne, Switzerland, 4(803983):1, (2022). https://doi.org/10.3389/ftox.2022.803983

Mortensen, H., T. Allen, J. Senn, G. Patlewicz, AND I. Shah. Assessing Machine Learning Methods in the Identification and Quantification of Environmental Chemical-Key Event Pairs Associated with Adverse Health Outcomes. Society of Toxicology 2021 Virtual Annual Meeting, RTP, NC, March 12 - 26, 2021. https://doi.org/10.23645/epacomptox.14466138

Beach, B., W. Slaughter, G. Chan, P. Harten, H. Mortensen, W. Boyes, AND A. Williams. EPA ORD NaKnowBase (NKB): Nanomaterial Database Development for Access and Collaboration. QSAR 2021, DURHAM, North Carolina, June 07 - 10, 2021.

Mortensen, H. Integrating Diverse nanoEHS data in EPA NaKnowBase: the DIG Central Repository. Integrating diverse nanoEHS data in EPA NaKnowBase: Work session 1, RTP, NC, June 11, 2021.

Mei, L., M. Martens, P. Nymark, C. Wittwehr, AND H. Mortensen. MODELLING THE EFFECT OF METAL NANOMATERIAL INDUCED INFLAMMATION ON THE BRADYKININ SYSTEM TO ELUCIDATE COVID-19 PATHOGENESIS USING THE ADVERSE OUTCOME PATHWAY FRAMEWORK: THE CIAO PROJECT. Society of Toxicology-Virtual, DURHAM, NORTH CAROLINA, March 07 - 13, 2021.

Mortensen, H. Opening remarks for WC11 S67: Using the Sematic Web for Rapid Integration of Publicly Available Biological Information (Innovative technologies Theme). 11th edition of the World Congress on Alternatives and Animal Use in the Life Sciences, RTP, NC, August 23 - September 02, 2021.

Mortensen, H. Editorial: Modernization of chemical risk assessment to make use of novel toxicological data. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, 394:114951, (2020). https://doi.org/10.1016/j.taap.2020.114951

Mortensen, H. Invited presentation: Tools to retrieve Relevant AOP information. OECD Webinar on Adverse Outcome Pathway Knowledgebase (AOP-KB) and AOP developing Tips, Paris, FRANCE, January 30, 2020.

Boyes, W., P. Langley, B. Beach, T. Levey, AND H. Mortensen. NaKnowBase User Interface. U.S. Environmental Protection Agency, Washington, DC, 2019.

Pittman, M., S. Edwards, C. Ives, AND H. Mortensen. AOP-DB: A Database Resource for the Exploration of Adverse Outcome Pathways Through Integrated Association Networks. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, 343:71-83, (2018).

Chamberlin, J. AND H. Mortensen. Computational Integration of Human Genetic and Toxicological Data to Evaluate AOP-Specific Susceptibility. Society of Toxicology, San Antonio, TX, March 11 - 15, 2018.

Mortensen, H., J. Chamberlin, B. Joubert, M. Angrish, N. Sipes, JaniceS Lee, AND S. Euling. Leveraging human genetic and adverse outcome pathway (AOP) data to inform susceptibility in human health risk assessment. Mammalian Genome. Springer, New York, NY, 29(1):190-204, (2018).

Beach, B., L. Degn, L. Thornton, H. Mortensen, AND W. Boyes. NaKnowBase: a nanomaterials relational database populated with extant data from the EPA Office of Research and Development (ORD). SOT Annual Meeting, San Antonio, TX, March 11 - 15, 2018.

Langley, P., E. Kazymova, B. Vallanat, AND H. Mortensen. Aop-Db Frontend: A User Interface for the Adverse Outcome Pathways Database (2017). Genetics and Environmental Mutagenesis Society Fall Meeting, RTP, NC, November 07, 2017.

Chamberlin, J., S. Euling, AND H. Mortensen. Computational Integration of Human Genetic Data to Evaluate AOP-Specific Susceptibility. Genetics and Environmental Mutagenesis Society Fall Meeting, RTP, NC, November 07, 2017.

Mortensen, H., M. Pittman, C. LaLone, AND S. Edwards. Defining a Computational Framework for the Assessment of Taxonomic Applicability. SOT, Baltimore, MD, March 12 - 16, 2017.

Thornton, L., H. Mortensen, S. Al-Abed, AND W. Boyes. NaKnowBaseTM: The EPA Nanomaterials Research Database. Society of Toxicology, Baltimore, MD, March 12 - 16, 2017.

Boyes, W., S. Al-Abed, L. Degn, P. Harten, H. Mortensen, B. Beach, AND L. Thornton. “NaKnowBase”: A Nanomaterials Relational Database. U.S. Environmental Protection Agency, Washington, DC, EPA/600/C-18/004, 2017.

Oki, N., M. Nelms, S. Bell, H. Mortensen, AND S. Edwards. Accelerating Adverse Outcome Pathway Development Using Publicly Available Data Sources. Current Environmental Health Reports. Springer International Publishing AG, Cham (ZG), Switzerland, , 1-11, (2016).

Pittman, M., C. LaLone, Dan Villeneuve, G. Ankley, S. Edwards, AND H. Mortensen. Defining the Biological Domain of Applicability of Adverse Outcome Pathways Across Diverse Species: The Estrogen Receptor/Aromatase Case Study. Genetics and Environmental Mutagenesis Societies Annual Fall Meeting, Durham, NC, October 28, 2015.