Science Inventory

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JUDSON, R., H. M. MORTENSEN, I. A. SHAH, T. B. KNUDSEN, AND F. ELLOUMI. Using pathway modules as targets for assay development in xenobiotic screening . Molecular BioSystems. RSC Publishing, Cambridge, Uk, 8(2):531-542, (2012).

KNUDSEN, T. B., K. A. HOUCK, N. SIPES, A. V. SINGH, R. JUDSON, M. T. MARTIN, A. WEISSMAN, N. KLEINSTREUER, H. M. MORTENSEN, D. REIF, J. R. RABINOWITZ, R. W. SETZER, A. M. RICHARD, D. J. DIX, AND R. J. KAVLOCK. Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets. TOXICOLOGY. Elsevier Ireland Limited, Limerick, Ireland, 282(1-2):1-15, (2011).

MORTENSEN, H. M. AND S. EULING. Integrating mechanistic and polymorphism data to characterize human genetic susceptibility for environmental chemical risk assessment in the 21st century. TOXICOLOGY AND APPLIED PHARMACOLOGY. Elsevier BV, AMSTERDAM, Netherlands, (Online):1-10, (2011).

REIF, D., M. T. MARTIN, H. M. MORTENSEN, S. GANGWAL, A. WANG, R. JUDSON, P. VOLARATH, R. J. KAVLOCK, AND D. J. DIX. Prioritizing ToxCast Chemicals Across Multiple Sectors of Toxicity Using ToxPi. Presented at Annual Meeting of the Society of Toxicology, Washington, DC, March 06 - 10, 2011.

MORTENSEN, H. M., D. REIF, D. J. DIX, T. B. KNUDSEN, K. A. HOUCK, R. J. KAVLOCK, AND R. JUDSON. Identifying Functionally Linked Gene Modules Within Biological Pathways Assessed by ToxCast In Vitro Assays. Presented at Society of Toxicology Annual Meeting, Salt Lake City, UT, March 07 - 11, 2010.

JUDSON, R., K. A. HOUCK, R. J. KAVLOCK, T. B. KNUDSEN, M. T. MARTIN, H. M. MORTENSEN, D. REIF, D. ROTROFF, I. A. SHAH, A. M. RICHARD, AND D. J. DIX. In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 118(4):485-92, (2010).

MORTENSEN, H. M. Application of the ToxMiner Database: Network Analysis Linking the ToxCast Chemicals to Known Disease-Gene Associations. Presented at ToxCast Data Analysis Summit, RTP, NC, May 14 - 15, 2009.

MORTENSEN, H. M., D. J. DIX, K. A. HOUCK, R. J. KAVLOCK, I. A. SHAH, AND R. JUDSON. Application of the ToxMiner Database: Network Analysis of Linkage between ToxCast Phase I Chemicals and Thyroid Related Disease Outcomes. Presented at ToxCast Data Analysis Summit, RTP, NC, May 14 - 15, 2009.

JUDSON, R., D. J. DIX, K. A. HOUCK, M. T. MARTIN, H. M. MORTENSEN, AND R. J. KAVLOCK. Developing Predictive Toxicity Signatures Using In Vitro Data from the EPA ToxCast Program. Presented at Society of Toxicology Annual Meeting, Baltimore, MD, March 15 - 19, 2009.

MORTENSEN, H. M., D. REIF, D. J. DIX, K. A. HOUCK, R. J. KAVLOCK, AND R. JUDSON. Evaluating the Toxicity Pathways Using High-Throughput Environmental Chemical Data. Presented at Computational Toxicology Board of Scientific Counselors Review, RTP, NC, September 29 - 30, 2009.

MORTENSEN, H. M. Genetic Variation at the N-acetyltransferase (NAT) Genes in Global Populations. Presented at 2009 EMS Annual Meeting: Symposium 4 Genetic Polymorphisms in Metabolism of Drugs and Environmental Agents in Disease and in Health Risk Assessment, St. Louis, MO, October 24 - 28, 2009.

JUDSON, R., K. A. HOUCK, R. J. KAVLOCK, T. B. KNUDSEN, M. T. MARTIN, H. M. MORTENSEN, D. REIF, A. M. RICHARD, D. ROTROFF, I. A. SHAH, AND D. J. DIX. High Throughput Screening of Toxicity Pathways Perturbed by Environmental Chemicals. Presented at ToxCast Data Analysis Summit, RTP, NC, May 14 - 15, 2009.

MORTENSEN, H. M. Mapping Human Toxicity and Disease Pathways in ToxCast. Presented at ToxCast Data Analysis Summit, RTP, NC, May 14 - 15, 2009.

MORTENSEN, H. M. Mapping Human Toxicity and Disease Pathways in ToxCast (s). Presented at as an invited presentation at Pfizer, Groton, CT, August 13, 2009.

JUDSON, R., D. J. DIX, K. A. HOUCK, T. B. KNUDSEN, I. A. SHAH, D. REIF, M. T. MARTIN, H. M. MORTENSEN, D. ROTROFF, AND R. J. KAVLOCK. Modeling and Predicting Cancer from ToxCast Phase I Data. Presented at Computational Toxicology Board of Scientific Counselors Review, RTP, NC, September 29 - 30, 2009.

DIX, D. J., K. A. HOUCK, R. JUDSON, T. B. KNUDSEN, S. LITTLE, M. T. MARTIN, H. M. MORTENSEN, D. REIF, A. M. RICHARD, R. W. SETZER, J. F. WAMBAUGH, A. BEAM, D. ROTROFF, M. WOLF, AND R. J. KAVLOCK. The Second Phase of ToxCast and Initial Applications to Chemical Prioritization. Presented at Computational Toxicology Board of Scientific Counselors Review, RTP, NC, September 29 - 30, 2009.

MORTENSEN, H. M., D. J. DIX, K. A. HOUCK, R. J. KAVLOCK, I. A. SHAH, AND R. JUDSON. The ToxCast Pathway Database for Identifying Toxicity Signatures and Potential Modes of Action from Chemical Screening Data. Presented at Society of Toxicology Annual Meeting, Baltimore, MD, March 15 - 19, 2009.

MORTENSEN, H. M., D. J. DIX, K. A. HOUCK, R. J. KAVLOCK, AND R. JUDSON. Using the ToxMiner Database for Identifying Disease-Gene Associations in the ToxCast Dataset. Presented at National Academy of Sciences Symposium on Toxicity Pathway-Based Risk Assessment , Washington, DC, May 11 - 13, 2009.

MORTENSEN, H. M., D. J. DIX, K. A. HOUCK, R. J. KAVLOCK, AND R. JUDSON. Using the ToxMiner Database for a Network Analysis of Linkage between ToxCast Phase I Chemicals and Thyroid Related Disease Outcomes. Presented at ToxCast Data Analysis Summit, RTP, NC, May 14 - 15, 2009.