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Records 1 to 25 of 159 records from author Chris Corton

2024
Corton, Jon, V. Ledbetter, S. Cohen, E. Atlas, C. Yauk, AND J. Liu. A transcriptomic biomarker predictive of cell proliferation for use in adverse outcome pathway-informed testing (SOT 24). Society of Toxicology (SOT) 63rd Annual Meeting and ToxExpo, Salt Lake City, NV, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25443715
Corton, Jon. Methods to Identify Hazards in Produced Water. Colorado Produced Water Board Meeting, Durham, NC, April 05, 2024. https://doi.org/10.23645/epacomptox.25678179
2023
Ledbetter, V., S. Auerbach, L. Everett, B. Vallanat, A. Lowit, G. Akerman, M. Devito, AND C. Corton. A New Approach Methodology for the Prediction of Tumorigenesis. Society of Toxicology 62nd Annual Meeting and ToxExpo 2023, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.24450235
Ledbetter, V., S. Auerbach, L. Everett, B. Vallanat, A. Lowit, G. Akerman, M. Devito, AND Jon Corton. A New Approach Methodology for the Prediction of Tumorigenesis (NCSOT 23). North Carolina Society of Toxicology (NCSOT) Annual Meeting, Durham, NC, September 14, 2023. https://doi.org/10.23645/epacomptox.25757916
Matteo, G., K. Leingartner, A. Rowan-Carroll, M. Meier, A. Williams, M. Beal, M. Gagne, R. Farmahin, S. Wickramasuriya, A. Reardon, T. Barton-Maclaren, Jon Corton, C. Yauk, AND E. Atlas. In vitro transcriptomic analyses reveal pathway perturbations, estrogenic activities, and potencies of data-poor BPA alternative chemicals. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 191(2):266-275, (2023). https://doi.org/10.1093/toxsci/kfac127
Strupp, C., M. Corvaro, S. Cohen, Jon Corton, K. Ogawa, L. Richert, AND M. Jacobs. Increased Cell Proliferation as a Key Event in Chemical Carcinogenesis: Application in an Integrated Approach for the Testing and Assessment of Non-Genotoxic Carcinogenesis. International Journal of Molecular Sciences. MDPI, Basel, Switzerland, 24(17):13246, (2023). https://doi.org/10.3390/ijms241713246
Berry, C., S. Cohen, Jon Corton, J. Lauro Viana de Camargo, G. Eisenbrand, S. Fukushima, H. Greim, K. Weber, I. Reitjens, AND C. Strupp. Letter to the Editors regarding “10% Body weight (gain) change as criterion for the maximum tolerated dose: A critical analysis”. REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, 139:105362, (2023). https://doi.org/10.1016/j.yrtph.2023.105362
Corton, C. Systematic Analysis of High-Throughput Transcriptomics to Identify Potential Carcinogens. Society of Toxicology 62nd Annual Meeting and ToxExpo 2023, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.23457839
Corton, Jon. Using Transcript Profiling to Identify Carcinogens. Physicians Committee for Responsible Medicine (PCRM) and New Approach Methodologies (NAM) Use for Regulatory Applications (NURA) Webinar series, RTP/Virtual, NC, March 09, 2023. https://doi.org/10.23645/epacomptox.22766714
2022
Corton, Jon, C. Mitchell, S. Auerbach, P. Bushel, H. Ellinger-Ziegelbauer, P. Escobar, R. Froetschl, A. Harrill, K. Johnson, J. Klaunig, A. Pandiri, A. Podtelezhnikov, J. Rager, K. Tanis, J. van der Laan, A. Vespa, C. Yauk, S. Pettit, AND F. Sistare. A Collaborative Initiative to Establish Genomic Biomarkers for Assessing Tumorigenic Potential to Reduce Reliance on Conventional Rodent Carcinogenicity Studies. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 188(1):4-16, (2022). https://doi.org/10.1093/toxsci/kfac041
Corton, C., J. Liu, A. Williams, E. Cho, AND C. Yauk. A Gene Expression Biomarker Identifies Inhibitors of Two Classes of Epigenome Effectors in a Human Microarray Compendium. Environmental Mutagenesis and Genomics Society (EGMS) and 13th International Conference on Environmental Mutagens (ICEM), Ottawa, N/A, CANADA, August 27 - September 01, 2022. https://doi.org/10.23645/epacomptox.23280269
Ledbetter, V., S. Auerbach, L. Everett, B. Vallanat, A. Lowit, G. Akerman, M. Devito, AND C. Corton. A New Approach Methodology for the Prediction of Tumorigenesis in the Rat. North Carolina Society of Toxicology 2022 annual meeting, Durham, NC, October 19, 2022. https://doi.org/10.23645/epacomptox.21372006
Ledbetter, V., S. Auerbach, L. Everett, B. Vallanat, A. Lowit, G. Akerman, M. Devito, AND C. Corton. A New Approach Methodology for the Prediction of Tumorigenesis in the Rat (GEMS). Genetics and Environmental Mutagenesis Society Meeting, RTP, NC, November 01, 2022. https://doi.org/10.23645/epacomptox.23502141
Korunes, K., J. Liu, R. Huang, M. Xia, K. Houck, AND C. Corton. A gene expression biomarker for predictive toxicology to identify chemical modulators of NF-κB. PLOS ONE . Public Library of Science, San Francisco, CA, 17(2):e0261854, (2022). https://doi.org/10.1371/journal.pone.0261854
Corton, C. Activation Levels of MIE Transcriptional Biomarkers Identify Liver Tumorigenic Dose Levels. Environmental Mutagenesis and Genomics Society (EGMS) and 13th International Conference on Environmental Mutagens (ICEM), Ottawa, N/A, CANADA, August 27 - September 01, 2022. https://doi.org/10.23645/epacomptox.23280206
Corton, Jon, J. Lee, J. Liu, H. Ren, B. Vallanat, AND M. Devito. Determinants of Gene Expression in the Human Liver: Impact of Aging and Sex on Xenobiotic Metabolism. Experimental Gerontology. Elsevier Science Ltd, New York, NY, 169:111976, (2022). https://doi.org/10.1016/j.exger.2022.111976
Meier, M., A. Williams, K. Cook, C. Corton, L. Everett, J. Harrill, AND C. Yauk. High-throughput transcriptomics and chemical toxicity testing: quality control approaches to enhance consistency and reproducibility. Environmental Mutagenesis and Genomics Society (EGMS) Meeting, Ottawa, N/A, CANADA, August 27 - September 01, 2022. https://doi.org/10.23645/epacomptox.23338073
Corton, C. Uncovering chemical toxicity by high-throughput transcript profiling: linking molecular targets to potential adverse effects. Physicians Committee for Responsible Medicine Summer School on Innovative Approaches in Science, Durham, NC, June 09, 2022. https://doi.org/10.23645/epacomptox.20134379
2021
Rooney, J., N. Ryan, J. Liu, R. Houtman, R. van Beuningen, J. Hsieh, G. Chang, S. Chen, AND Jon Corton. A Gene Expression Biomarker Identifies Chemical Modulators of Estrogen Receptor α in an MCF-7 Microarray Compendium. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 34(2):313-329, (2021). https://doi.org/10.1021/acs.chemrestox.0c00243
Cervantes, P. AND C. Corton. A Gene Expression Biomarker Predicts Heat Shock Factor 1 Activation in a Gene Expression Compendium. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 34(7):1721-1737, (2021). https://doi.org/10.1021/acs.chemrestox.0c00510