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Records 51 to 75 of 76 records from [ORD-NCCT] published between 03/25/2014 and 03/25/2019 from author Keith Houck

2015
Franzosa, J., J. Jack, P. Kothiya, D. Filer, J. Liu, J. Bonzo, S. Ferguson, I. Shah, A. Richard, R. Thomas, J. Wambaugh, AND K. Houck. Evaluation of In Vitro Biotransformation Using HepaRG Cells to Improve High-Throughput Chemical Hazard Prediction: A Toxicogenomics Analysis (SOT). Presented at 2015 Annual SOT Meeting, San Diego, CA, March 22 - 26, 2015. https://doi.org/10.23645/epacomptox.5178868
Patlewicz, G., K. Houck, R. Judson, A. Richard, I. Shah, AND A. Williams. Exploiting enhanced non-testing approaches to meet the needs for sustainable chemistry. Presented at ACS Meeting, Boston, MA, August 16 - 20, 2015. https://doi.org/10.23645/epacomptox.5077792
Connors, K., D. Filer, N. Sipes, R. Judson, K. Houck, AND M. Martin. High content screening of ToxCast compounds using Vala Sciences’ complex cell culturing systems (SOT). Presented at SOT Annual Meeting, San Deigo, CA, March 22 - 26, 2015. https://doi.org/10.23645/epacomptox.5178847
Wetmore, B., John F. Wambaugh, B. Allen, S. Ferguson, M. Sochaski, R. Woodrow Setzer, Keith A. Houck, C. Strope, K. Cantwell, Richard S. Judson, E. LeCluyse, H. Clewell III, Russell S. Thomas, AND M. Andersen. Incorporating High-Throughput Exposure Predictions with Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, , 1-57, (2015).
Judson, Richard S., F. Magpantay, V. Chickarmane, C. Haskell, N. Tania, J. Taylor, M. Xia, R. Huang, D. Rotroff, D. Filer, K. Houck, M. Martin, N. Sipes, A. Richard, K. Mansouri, Woodrow Setzer, T. Knudsen, K. Crofton, AND R. Thomas. Integrated Model of Chemical Perturbations of a Biological PathwayUsing 18 In Vitro High Throughput Screening Assays for the Estrogen Receptor. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, :1-42, (2015).
Houck, K. Phenotypic Screening of Primary Human Cell Culture Systems to Identify Potential for Compound Toxicity (CHI Phenotypic Screening). Presented at Cambridge Healthtech Institute’s Phenotypic Screening, San Diego, CA, January 26 - 27, 2015. https://doi.org/10.23645/epacomptox.5080015
Franzosa, J., D. Mahapatra, K. Connors, R. Huang, M. Xia, R. Thomas, S. Kullman, AND K. Houck. Quantitative High-Throughput Screening and Orthogonal Assays to Identify Modulators of the Vitamin D Receptor (SETAC). Presented at SETAC, Salt Lake City, UT, November 01 - 05, 2015. https://doi.org/10.23645/epacomptox.5189329
Houck, K. The ToxCast Chemical Prioritization Program at the US EPA (UCLA Molecular Toxicology Program). Presented at UCLA Molecular Toxicology Program, Los Angeles, CA, November 12, 2015. https://doi.org/10.23645/epacomptox.5071285
Houck, K. The US EPA's ToxCast Project: A Public Resource for Environmental Chemical High-Throughput Testing Data (OpenTox Euro). OpenTox EURO 2015, Dublin, IRELAND, September 30 - October 02, 2015. https://doi.org/10.23645/epacomptox.5080030
2014
Houck, K., R. Coleman, K. Tsaioun, AND K. Archibald. A Real-time Evaluation of Human-based Approaches to Safety Testing: What We Can Do Now (TDS). Presented at ToxCast Data Summit, RTP, NC, September 29 - 30, 2014. https://doi.org/10.23645/epacomptox.5193409
Houck, K. BioMap Profiling of the EPA ToxCast Chemical Library (SOT workshop). Presented at SOT Workshop: Analysis of Failed Pharmaceutical Compounds in the BioMAP Platform of Primary Human Cell Systems, Phoenix, AZ, March 25, 2014.
Houck, K. Bioactivity Profiling of Environmental Chemicals in the EPA’s ToxCast Program (NCSU). Presented at North Carolina State University: Department of Environmental and Molecular Toxicology Seminar Series, Raleigh, NC, April 08, 2014. https://doi.org/10.23645/epacomptox.5082412
Houck, K. Bioactivity Profiling using Primary Human Cell Systems in Support of Predictive Toxicology (CPCP presentation). Presented at Chemical Prioritization Community of Practice, RTP, NC, October 23, 2014.
Houck, K., S. Mosher, S. Frady, J. Liu, J. Phuong, D. Filer, R. Judson, M. Martin, J. Wambaugh, P. Kothiya, J. Franzosa, AND S. Padilla. Considerations in Use of the EPA’s ToxCast Data for Environmental Toxicology (SETAC). SETAC North America 35th Annual Meeting, Vancouver, BC, CANADA, November 09 - 13, 2014. https://doi.org/10.23645/epacomptox.5080033
Wetmore, B., M. Black, E. Berg, M. Polokoff, K. Houck, R. Judson, R. Thomas, AND M. Anderson. In Vitro Bioactivity in ToxCast Assays for Fruit and Vegetable Juices (TDS). Presented at ToxCast Data Summit, RTP, NC, September 29 - 30, 2014. https://doi.org/10.23645/epacomptox.5197186
Judson, R., K. Houck, M. Martin, A. Richard, T. Knudsen, N. Sipes, I. Shah, S. Little, J. Wambaugh, Woodrow Setzer, J. Rabinowitz, M. Linnenbrink, J. Franzosa, P. Kothiya, J. Phuong, K. McLaurin, D. Filer, M. Leung, C. Strope, L. Truong, R. Thomas, D. Smith, D. Reif, D. Rotroff, N. Kleinstreuer, M. Xia, AND R. Huang. In Vitro Screening of 1877 Industrial and Consumer Chemicals, Pesticides and Pharmaceuticals in up to 782 Assays: ToxCast Phase I and II (SOT). Presented at SOT, Pheonix, AZ, March 23 - 27, 2014. https://doi.org/10.23645/epacomptox.5193274
Houck, K. In Vitro Testing of Engineered Nanomaterials in the EPA’s ToxCast Program (WC9). Presented at 9th World Congress on Alternatives and Animal Use in the Life Sciences, Prague, CZECH REPUBLIC, August 24 - 28, 2014. https://doi.org/10.23645/epacomptox.5082376
Judson, R., K. Houck, M. Martin, T. Knudsen, R. Thomas, N. Sipes, I. Shah, J. Wambaugh, AND K. Crofton. In Vitro and Modeling Approaches to Risk Assessment from the U.S. Environmental Protection Agency ToxCast Program. BASIC AND CLINICAL PHARMACOLOGY AND TOXICOLOGY. Blackwell Publishing, Malden, MA, 115(1):69-76, (2014).
Houck, K. Overview of Tools and Data Sources of the ToxCast Chemical Prioritization Program (ACS Green Chem). Presented at ACS Green Chemistry & Engineering Conference, Bethesda, MD, June 16 - 19, 2014.
Kleinstreuer, N., J. Yang, E. Berg, T. Knudsen, A. Richard, M. Martin, D. Reif, R. Judson, M. Polokoff, D. Dix, R. Kavlock, AND K. Houck. Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms. Nature Biotechnology. Elsevier Science, New York, NY, 32(6):583-591, (2014).
Houck, K., N. Kleinstreuer, J. Yang, E. Berg, T. Knudsen, A. Richard, M. Martin, D. Reif, R. Judson, AND M. Polokoff. Predicting Toxic and Therapeutic Mechanisms of the ToxCast Chemical Library by Phenotypic Screening (SOT). Presented at SOT 2014 Annual Conference, Phoenix, AZ, March 23 - 27, 2014. https://doi.org/10.23645/epacomptox.5193439
Rotroff, D., M. Martin, D. Dix, D. Filer, K. Houck, T. Knudsen, N. Sipes, D. Reif, M. Xia, R. Huang, AND R. Judson. Predictive Endocrine Testing in the 21st Century Using In Vitro Assays of Estrogen Receptor Signaling Responses. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 48:8706-8716, (2014).
Franzosa, J., K. Mansouri, J. Hsieh, S. Ferguson, X. Chang, N. Kleinstreurer, J. Hamm, Dan Villeneuve, R. Judson, R. Thomas, R. Huang, M. Xia, S. Kullman, M. Denison, AND K. Houck. Quantitative High-Throughput Screening and Confirmation Studies for Identification of Compounds that Activate the Aryl Hydrocarbon Receptor Pathway (SETAC). Presented at SETAC, Vancouver, BC, CANADA, November 09 - 12, 2014.
Houck, K. The ToxCast Chemical Prioritization Program at the US EPA (CFSAN/FDA meeting). Presented at FDA Regulatory Science Sympsium, Greenbelt, MD, June 12, 2014.