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Records 26 to 50 of 76 records from [ORD-NCCT] published between 03/25/2014 and 03/25/2019 from author Keith Houck

2017
Houck, K., C. LaLone, R. Judson, M. Martin, Dan Villeneuve, G. Ankley, A. Medvedev, AND S. Markarorav. Evaluation of an In Vitro Multi-Receptor and Multi-Species Assay for Potential Endocrine Disruptor Targets (SOT). Presented at SOT National Meeting, Baltimore, MD, March 12 - 16, 2017.
Bone, A., M. Xia, S. Sakamuru, R. Huang, R. Houtman, R. van Beuningen, Eric Watt, N. Kleinstreuer, R. Judson, AND K. Houck. Identification of Androgen Receptor Antagonists using Tox21 qHTS Data and the MARCoNI Assay. Society of Toxicology Annual Meeting, Baltimore,MD, March 12 - 16, 2017. https://doi.org/10.23645/epacomptox.6791795.v2
Lynch, C., S. Sakamuru, R. Huang, D. Stavea, L. Varticovski, G. Hager, Richard S. Judson, Keith A. Houck, N. Kleinstreuer, W. Casey, R. Paules, A. Simeonov, AND M. Xia. Identifying Environmental Chemicals as Agonists of the Androgen Receptor by Applying a Quantitative High-throughput Screening Platform. TOXICOLOGY. Elsevier Science Ltd, New York, NY, 385:48-58, (2017).
Judson, R., K. Houck, T. Knudsen, Eric Watt, S. Mosher, T. Tal, AND S. Padilla. Modeling Zebrafish Developmental Toxicity using a Concurrent In vitro Assay Battery (SOT). Presented at SOT 2017, Baltimore, MD, March 12 - 16, 2017. https://doi.org/10.23645/epacomptox.5178586
Judson, R., K. Houck, Eric Watt, AND R. Thomas. On Selecting a Minimal Set of In Vitro Assays to Reliably Determine Estrogen Agonist Activity. REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, 91:39-49, (2017).
Harrill, J., M. Martin, K. Houck, R. Judson, K. Crofton, AND R. Thomas. Optimization Of A High-Throughput Transcriptomic (HTTr) Bioactivity Screen In MCF7 Cells Using Targeted RNA-Seq (SOT). Presented at SOT annual meeting, Baltimore, MD, March 12 - 16, 2017. https://doi.org/10.23645/epacomptox.5176789
Paul-Friedman, K., J. Zhao, R. Huang, M. Xia, K. Crofton, AND K. Houck. Screening the Tox21 10K library for thyroid stimulating hormone receptor agonist and antagonist activity (SOT annual meeting). Presented at SOT Annual Meeting, Baltimore, Maryland, March 12 - 16, 2017. https://doi.org/10.23645/epacomptox.5176897
Flood, S. AND K. Houck. ToxCast Assay Descriptions (originally presented at CSS meeting, and will be released to external stakeholders). Presented at CSS monthly meeting, RTP, NC, April 10, 2017.
Houck, K. Toxicity Testing in the 21st Century EPA’s CompTox Approach (TAMU CVM lecture)EPA’s CompTox Approach (TAMU CVM). Presented at TA&MU CVM lecture, College Station, Texas, April 28, 2017.
Thomas, R., D. Zink, L. Loo, K. Houck, H. Yu, I. Shah, F. Ginhoux, AND T. Knudsen. US EPA - A*Star Partnership - Accelerating the Acceptance of Next-Generation Sciences and Their Application to Regulatory Risk Assessment (A*Star Symposium, Singapore). Presented at A*STAR Symposium, Singapore, Singapore, SINGAPORE, February 04 - 08, 2017.
2016
Judson, R., K. Houck, M. Martin, A. Richard, T. Knudsen, I. Shah, S. Little, J. Wambaugh, Woodrow Setzer, P. Kothiya, J. Phuong, D. Filer, D. Smith, D. Reif, D. Rotroff, N. Kleinstreuer, N. Sipes, M. Xia, R. Huang, K. Crofton, AND R. Thomas. Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 152(2):323-339, (2016).
Bone, A., G. Patlewicz, AND K. Houck. Evaluation and comparison of bisphenol A analog activity using ToxCast data (SOT). Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 13 - 17, 2016. https://doi.org/10.23645/epacomptox.5176606
Karmaus, A., D. Filer, M. Martin, AND K. Houck. Evaluation of food-relevant chemicals in the ToxCast high-throughput screening program. FOOD AND CHEMICAL TOXICOLOGY. Elsevier Science Ltd, New York, NY, 92:188-196, (2016).
Houck, K., A. Karmaus, A. Richard, AND J. Franzosa. Heavy Metals in ToxCast: Relevance to Food Safety (SOT). Presented at SOT, New Orleans, LA, March 13 - 17, 2016. https://doi.org/10.23645/epacomptox.5084224
Palmer, J., T. Knudsen, L. Egnash, P. Kothiya, K. Houck, AND B. Donley. Human Pluripotent Stem Cell-Based Assay Predicts Developmental Toxicity Potential of ToxCast Chemicals (ACT meeting). Presented at American College of Toxicology, Baltimore, MD, November 06 - 09, 2016. https://doi.org/10.23645/epacomptox.5181325
Simmons, Steve, Eric Watt, K. Paul-Friedman, K. Houck, R. Judson, M. Hornung, AND K. Crofton. Identification of Chemical Features Linked to Thyroperoxidase Inhibition (SOT). Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 13 - 17, 2016. https://doi.org/10.23645/epacomptox.5155789
Franzosa, J., J. Liu, R. Thomas, J. Wambaugh, K. Houck, AND I. Shah. Prediction of in vivo hepatotoxicity effects using in vitro transcriptomics data (SOT). Presented at SOT annual meeting, New Orleans, LA, March 13 - 17, 2016. https://doi.org/10.23645/epacomptox.5176498
Richard, A., R. Judson, K. Houck, C. Grulke, P. Volarath, I. Thillainadarajah, C. Yang, J. Rathman, M. Martin, J. Wambaugh, T. Knudsen, K. Mansouri, J. Kancherla, G. Tier, A. Williams, S. Little, K. Crofton, AND R. Thomas. The ToxCast Chemical Landscape - Paving the Road to 21st Century Toxicology. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 29(8):1225-1251, (2016).
Paul-Friedman, K., Eric D. Watt, Michael W. Hornung, Joan M. Hedge, Richard S. Judson, Kevin M. Crofton, Keith A. Houck, AND Steven O. Simmons. Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors within the ToxCast Phase I and II Chemical Libraries. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 151(1):160-180, (2016).
Knudsen, T., P. Kothiya, AND K. Houck. Toxcast Profiling in a Human Stem Cell Assay for Developmental Toxicity (SOT). Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 13 - 17, 2016. https://doi.org/10.23645/epacomptox.5155729
Shah, I., Woodrow Setzer, J. Jack, K. Houck, R. Judson, T. Knudsen, J. Liu, M. Martin, D. Reif, Ann M. Richard, Russell S. Thomas, K. Crofton, David J. Dix, AND Robert J. Kavlock. Using ToxCast data to reconstruct dynamic cell state trajectories and estimate toxicological points of departure. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 124(7):910-919, (2016).
2015
Richter, A., J. Brown, B. Bharti, A. Wang, S. Gangwal, K. Houck, E. Hubal, V. Paunov, S. Stoyanov, AND O. Velev. An environmentally benign antimicrobial nanoparticle based on a silver-infused lignin core. Nature Nanotechnology. Nature Publishing Group, London, Uk, 10(9):817-823, (2015).
Houck, K. Analysis of Chemical Bioactivity through In Vitro Profiling using ToxCast and Tox21 High-Throughput Screening (China tox. conf. TATT). Presented at Annual Conference on Toxicological Alternatives and Translational Toxicology, Xi'An, CHINA, July 26 - 29, 2015. https://doi.org/10.23645/epacomptox.5080027
Knudsen, T. B., A. M. Richard, P. G. Kothiya, R. S. Judson, K. A. Houck, K. C. Crofton, R. S. Thomas, S. Little, E. S. Hunter, N. C. Baker, C. K. M. Leung, J. Palmer, A. Smith, M. Colwell, P. West, R. Burrier, AND L. Egnash. Evaluation of 1066 ToxCast Chemicals in a human stem cell assay for developmental toxicity (SOT). Presented at Society of Toxicology, San Diego, CA, March 21 - 26, 2015. https://doi.org/10.23645/epacomptox.5178703