Science Inventory

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Kuo, B., J. Wills, P. White, F. Marchetti, A. Nong, A. Williams, K. Houck, R. Tice, AND C. Yauk. A High-throughput Analytical Framework for Efficient Analysis of In Vitro Micronucleus (MN) Dose-response Data. Health Canada Science Forum, OttawaC, March 08 - 09, 2018. https://doi.org/10.23645/epacomptox.6947897

Sipes, N., R. Huang, K. Shockley, M. Martin, R. Judson, K. Houck, A. Shapiro, J. Addington, S. Auerbach, H. Hong, R. Paules, AND J. Hsieh. Concordance in Modeling Concentration-Response Data: Tox21 10k Library Pipeline Comparison. Presented at OpenTox USA, RTP, NC, July 11 - 12, 2018.

Sipes, N., R. Huang, K. Shockley, M. Martin, A. Shapiro, J. Addington, S. Auerbach, R. Paules, R. Judson, K. Houck, H. Hong, AND J. Hsieh. Confidence in Fitting and Hitting Concentration-Response Data: Tox21 10k Library Pipeline Comparison. Presented at Society of Toxicology Annual Meeting, San Antonio, TX, March 11 - 15, 2018. https://doi.org/10.23645/epacomptox.6945911

Mahapatra, D., Jill A. Franzosa, K. Roell, M. Kuenemann, Keith A. Houck, D. Reif, D. Fourches, AND S. Kullman. Confirmation of High-Throughput screening data and novel mechanistic insights into VDR-xenobiotic interactions by orthogonal assays. Scientific Reports. Nature Publishing Group, London, Uk, 8(8883):1-16, (2018). https://doi.org/10.1038/s41598-018-27055-3

Flood, S. AND K. Houck. Development and Distribution of Test Method Documentation for ToxCast HTT Assays. Presented at SETAC North America Focused Topic Meeting : High-Throughput Screening, Durham, NC, April 16 - 18, 2018. https://doi.org/10.23645/epacomptox.6948023

Flood, S. AND K. Houck. Development and Distribution of ToxCast and Tox21 HTS Assay Method Descriptions. CompTox Communities of Practice, RTP,NC, January 25, 2018.

Blackwell, B., G. Ankley, P. Bradley, K. Houck, J. Swintek, AND Dan Villeneuve. Evaluation of in vitro bioactivity of surface waters from a nationwide assessment of United States streams. SETAC Focused Topic Meeting, Durham, NC, April 16 - 18, 2018.

Houck, K. AND A. Bone. Filling in the Gaps: The Role Functional Genomics Can Play in 21st Century Toxicology. Presented at Society of Toxicology Meeting, San Antonio, TX, March 11 - 15, 2018. https://doi.org/10.23645/epacomptox.6946166

Houck, K. Filling in the Gaps: The role functional genomics can play in 21st century toxicology for environmental risk assessment. Presented at National Academy of Science Workshop, Washington, DC, January 10 - 11, 2018. https://doi.org/10.23645/epacomptox.7029011

Judson, R., K. Paul-Friedman, K. Houck, K. Mansouri, P. Browne, AND N. Kleinstreuer. New Approach Methods for Testing Chemicals for Endocrine Disruption Potential. Current Opinion in Toxicology. Elsevier BV, AMSTERDAM, Netherlands, 9:40-47, (2018). https://doi.org/10.1016/j.cotox.2018.10.002

Houck, K., A. Bone, K. Paul-Friedman, C. Hsu, S. Sakamuru, M. Xia, R. Huang, V. Soni, D. Stavreva, AND K. Crofton. Screening the 10K Tox21 chemical library for thyroid hormone receptor modulators. Society of Toxicology, San Antonio, TX, March 11 - 15, 2018.

Houck, K. Understanding the Biology and Technology of ToxCast and Tox21 Assays. Society of Environmental Toxicology and Chemistry, Durham, NC, April 16 - 18, 2018. https://doi.org/10.23645/epacomptox.6265523

Houck, K. Update on the ToxCast Chemical Prioritization Project. Presented at California Breast Cancer Research Program, Oakland, CA, February 12 - 14, 2018. https://doi.org/10.23645/epacomptox.7029203

Houck, K. Use of the ToxCast and Tox21 Screening Strategies in Support of Chemical Prioritization for Risk Assessment. Presented at Presentation at Wageningen University June 2018, Wageningen, N/A, NETHERLANDS, June 18, 2018. https://doi.org/10.23645/epacomptox.7001291

Houck, K., C. LaLone, A. Bone, R. Judson, M. Martin, Dan Villeneuve, G. Ankley, A. Medvedev, AND S. Markarov. A Multi-Receptor and Multi-Species Assay for Potential Endocrine Disruptor Targets (SLAS meeting). Presented at 2017 SLAS meeting, Washington, DC, February 04 - 08, 2017. https://doi.org/10.23645/epacomptox.5181265

Blackwell, B., G. Ankley, S. Corsi, L. DeCicco, K. Houck, R. Judson, S. Li, M. Martin, E. Murphy, A. Schroeder, E. Smith, J. Swintek, AND Dan Villeneuve. An "EAR" on environmental surveillance and monitoring: A case study on the use of exposure-activity ratios (EARS) to prioritize sites, chemicals, and bioactivities of concern in Great Lakes waters. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 51(15):8713–8724, (2017).

Strickland, J., K. Wallace, M. Martin, K. Houck, J. Ross, AND Tim Shafer. Concentration-response assessment of ToxCast Phase II compounds on spontaneous neural network activity in vitro. 2017 Society of Toxicology Annual Meeting, Baltimore, MD, March 12 - 16, 2017.

Kleinstreuer, N., P. Ceger, Eric Watt, M. Martin, K. Houck, P. Browne, R. Thomas, W. Casey, D. Dix, D. Allen, S. Sakamuru, M. Xia, R. Huang, AND R. Judson. Development and Validation of a Computational Model for Androgen Receptor Activity. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 30(4):946-964, (2017).

Flood, S., K. Houck, AND Chris Grulke. Development of a Context-Rich Database of ToxCast Assay Annotations (SOT). Presented at SOT Annual Meeting, Baltimore, MD, March 12 - 16, 2017. https://doi.org/10.23645/epacomptox.5178610

Houck, K. EPA’s ToxCast Program: Update on CBCRP-Relevant Work (CBCRP Annual Meeting). Presented at CBCRP Annual Meeting, Berkeley, California, April 06, 2017. https://doi.org/10.23645/epacomptox.5056819

Houck, K., C. LaLone, R. Judson, M. Martin, Dan Villeneuve, G. Ankley, A. Medvedev, AND S. Markarorav. Evaluation of an In Vitro Multi-Receptor and Multi-Species Assay for Potential Endocrine Disruptor Targets (SOT). Presented at SOT National Meeting, Baltimore, MD, March 12 - 16, 2017.

Bone, A., M. Xia, S. Sakamuru, R. Huang, R. Houtman, R. van Beuningen, Eric Watt, N. Kleinstreuer, R. Judson, AND K. Houck. Identification of Androgen Receptor Antagonists using Tox21 qHTS Data and the MARCoNI Assay. Society of Toxicology Annual Meeting, Baltimore,MD, March 12 - 16, 2017. https://doi.org/10.23645/epacomptox.6791795.v2

Lynch, C., S. Sakamuru, R. Huang, D. Stavea, L. Varticovski, G. Hager, Richard S. Judson, Keith A. Houck, N. Kleinstreuer, W. Casey, R. Paules, A. Simeonov, AND M. Xia. Identifying Environmental Chemicals as Agonists of the Androgen Receptor by Applying a Quantitative High-throughput Screening Platform. TOXICOLOGY. Elsevier Science Ltd, New York, NY, 385:48-58, (2017).

Judson, R., K. Houck, T. Knudsen, Eric Watt, S. Mosher, T. Tal, AND S. Padilla. Modeling Zebrafish Developmental Toxicity using a Concurrent In vitro Assay Battery (SOT). Presented at SOT 2017, Baltimore, MD, March 12 - 16, 2017. https://doi.org/10.23645/epacomptox.5178586

Judson, R., K. Houck, Eric Watt, AND R. Thomas. On Selecting a Minimal Set of In Vitro Assays to Reliably Determine Estrogen Agonist Activity. REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, 91:39-49, (2017).