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2024
Viant, M., E. Amstalden, T. Athersuch, M. Bouhifd, S. Camuzeaux, D. Crizer, P. Driemert, T. Ebbels, D. Ekman, B. Flick, V. Giri, M. G?mez-Romero, V. Haake, M. Herold, A. Kende, F. Lai, P. Leonards, P. Lim, G. Lloyd, J. Mosley, C. Namini, J. Rice, S. Romano, C. Sands, M. Smith, T. Sobansky, A. Southam, L. Swindale, B. van Ravenzwaay, T. Walk, R. Weber, F. Zickgraf, AND H. Kamp. Demonstrating the reliability of in vivo metabolomics based chemical grouping: towards best practice. Archives of Toxicology. Springer, New York, NY, 98:1111-1123, (2024). https://doi.org/10.1007/s00204-024-03680-y
2023
Ankley, G., S. Corsi, C. Custer, D. Ekman, S. Hummel, K. Kimbrough, H. Schoenfuss, AND D. Villeneuve. Assessing Contaminants of Emerging Concern in the Great Lakes Ecosystem: A Decade of Method Development and Practical Application. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 42(12):2506-2518, (2023). https://doi.org/10.1002/etc.5740
Ekman, D., Y. Yue, Z. Huajun, T. Collette, P. Bradley, J. Mosley, AND Q. Teng. Assessing the Bioactivity of Surface Waters with Metabolomics Using Multiple Cell Lines. SETAC North America 44th Annual Meeting, Louisville, KY, November 12 - 16, 2023.
Amstalden, E., T. Athersuch, T. Ebbels, D. Ekman, D. Epps, V. Haake, H. Kamp, A. Kende, G. Lloyd, P. Leonards, J. Mosley, C. Sands, M. Viant, R. Weber, AND F. Zickgraf. Demonstrating the reliability of metabolomics-based chemical grouping: Towards acceptable practice. Metabolomics2023, Niagara Falls, CANADA, June 18 - 22, 2023.
Kamp, H., E. Amstalden, T. Athersuch, M. Bouhifd, T. Ebbels, D. Ekman, V. Haake, A. Kende, P. Leonards, J. Mosley, G. Lloyd, C. Sands, T. Sobansky, L. Swindale, T. Walk, R. Weber, F. Zickgraf, AND M. Viant. Demonstrating the reliability of metabolomics-based chemical grouping: Towards acceptable practice -- The metabolomics ring-trial for chemical grouping (MATCHING). 2023 Society of Toxicology Annual Meeting and ToxExpo, Nashville, TN, March 19 - 23, 2023.
Ekman, D., S. Romano, Q. Teng, A. Fox, S. Kornberg, AND T. Collette. Evaluation of Minimally Invasive Metabolomic Methods for Assessing the Sex and Health of Sturgeons. 153rd Annual Meeting of the American Fisheries Society, Grand Rapids, MI, August 20 - 24, 2023.
Ekman, D., M. Evich, J. Mosley, J. Doering, K. Fay, G. Ankley, AND T. Collette. Expanding non-invasive approaches for fish-health monitoring: A survey of the epidermal mucous metabolomes of phylogenetically diverse freshwater fish species. JOURNAL OF FISH BIOLOGY. Blackwell Publishing, Malden, MA, 103(5):1178-1189, (2023). https://doi.org/10.1111/jfb.15512
Bertolatus, D., L. Barber, C. Martyniuk, Z. Huajun, T. Collette, D. Ekman, A. Jastrow, J. Rapp, AND A. Vajda. Multi-omic Responses of Fish Exposed to Complex Chemical Mixtures in the Shenandoah River Watershed. SCIENCE OF THE TOTAL ENVIRONMENT. Elsevier BV, AMSTERDAM, Netherlands, 902:165975, (2023). https://doi.org/10.1016/j.scitotenv.2023.165975
2022
Villeneuve, D., D. Ekman, T. Collette, AND G. Ankley. Appendix E: Detecting and evaluating biological effects of contaminants of emerging concern in Great Lakes tributaries. U.S. Environmental Protection Agency, Washington, DC, 2022. https://doi.org/10.23645/epacomptox.21044455.v1
Blackwell, B., G. Ankley, A. Biales, J. Cavallin, A. Cole, T. Collette, D. Ekman, R. Hofer, W. Huang, K. Jensen, M. Kahl, A. Kittelson, S. Romano, M. See, Q. Teng, C. Tilton, AND D. Villeneuve. Effects of Metformin and its Metabolite Guanylurea on Fathead Minnow (Pimephales promelas) Reproduction (FY22 Manuscript). ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 41(11):2708-2720, (2022). https://doi.org/10.1002/etc.5450
Vitense, K., B. Blackwell, Tim Collette, S. Corsi, C. Custer, E. Davenport, D. Ekman, S. Hummel, S. Kohno, L. Loken, E. Maloney, AND E. Perkins. Prioritizing Chemicals of Emerging Concern in the Great Lakes Using Covariance of Chemical Concentrations and Diverse Biological Responses. SETAC, Durham, NC, November 13 - 17, 2022. https://doi.org/10.23645/epacomptox.21381855
Cavallin, J., C. Adams, L. Barber, B. Blackwell, P. Bradley, A. Cole, D. Ekman, N. Evans, S. Keefe, K. Keteles, J. Kinsey, E. MedlockKakaley, K. Romanok, K. Santana Rodriguez, K. Smalling, E. Stacy, D. Winkelman, AND Dan Villeneuve. Spatial and Temporal Distribution of Glucocorticoid and Estrogen Receptor-Mediated Bioactivities in Relation to a Wastewater Input on the South Platte River (Denver, CO, USA). Society of Environmental Toxicology and Chemistry (SETAC) North America, Pittsburgh, PA, November 13 - 17, 2022. https://doi.org/10.23645/epacomptox.21424551
Scholz, S., J. Nichols, B. Escher, G. Ankley, R. Altenburger, B. Blackwell, W. Brack, L. Burkhard, T. Collette, J. Doering, D. Ekman, K. Fay, F. Fischer, J. Hackermüller, J. Hoffman, C. Lai, D. Leuthold, D. Martinovic-Weigelt, T. Reemtsma, N. Pollesch, A. Schroeder, G. Schüürmann, AND M. Bergen. The Eco-Exposome Concept: Supporting an Integrated Assessment of Mixtures of Environmental Chemicals. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 41(1):30-45, (2022). https://doi.org/10.1002/etc.5242
Reichman, J., J. Steevens, R. Hockett, A. Farag, D. Harper, H. Ren, A. Fisher, N. Kimble, D. Ekman, AND M. Jankowski. Transcriptome Responses of Rainbow Trout and Chinook Salmon to Sub-Lethal Exposures to Zinc. SETAC North America, 43rd Annual Meeting, Pittsburgh, PA, November 13 - 17, 2022.
Evich, M., J. Mosley, I. Ntai, J. Cavallin, Dan Villeneuve, G. Ankley, Tim Collette, AND D. Ekman. Untargeted MSn-Based Monitoring of Glucuronides in Fish: Screening Complex Mixtures for Contaminants with Biological Relevance. ACS ES&T Water. American Chemical Society, Washington, DC, 2(12):2481–2490, (2022). https://doi.org/10.1021/acsestwater.2c00310
Mosley, J., M. Evich, I. Ntai, Tim Collette, J. Cavallin, Dan Villeneuve, G. Ankley, AND D. Ekman. Untargeted MSn-based Monitoring of Glucuronides in Fish: Screen-ing Complex Mixtures for Contaminants with Biological Relevance. 18th International Conference of the Metabolomics Society, Valencia, N/A, SPAIN, June 19 - 23, 2022.
2021
Cavallin, J., W. Battaglin, J. Beihoffer, B. Blackwell, P. Bradley, A. Cole, D. Ekman, R. Hofer, J. Kinsey, K. Keteles, D. Winkelman, AND Dan Villeneuve. Effects-Based Monitoring of Bioactive Chemicals Discharged to the Colorado River Before and After a Municipal Wastewater Treatment Plant Replacement. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 55(2):974-984, (2021). https://doi.org/10.1021/acs.est.0c05269
Cavallin, J., J. Beihoffer, B. Blackwell, A. Cole, D. Ekman, R. Hofer, A. Jastrow, J. Kinsey, K. Keteles, E. Maloney, J. Parman, D. Winkelman, AND Dan Villeneuve. Effects-based monitoring and prioritization of CECs: South Platte River Case Study. Consortium for Research and Education on Emerging Contaminants, Duluth, MN, October 21, 2021. https://doi.org/10.23645/epacomptox.17131571
Cavallin, J., J. Beihoffer, B. Blackwell, A. Cole, D. Ekman, R. Hofer, A. Jastrow, J. Kinsey, K. Keteles, E. Maloney, J. Parman, D. Winkelman, AND Dan Villeneuve. Effects-based monitoring of bioactive compounds associated with municipal wastewater treatment plant effluent discharge to the South Platte River, Colorado, USA. ENVIRONMENTAL POLLUTION. Elsevier Science Ltd, New York, NY, 289:117928, (2021). https://doi.org/10.1016/j.envpol.2021.117928
Ankley, G., J. Berninger, B. Blackwell, J. Cavallin, Tim Collette, D. Ekman, K. Fay, D. Feifarek, K. Jensen, M. Kahl, J. Mosley, S. Poole, E. Randolph, D. Rearick, A. Schroeder, J. Swintek, AND Dan Villeneuve. Pathway-based approaches for assessing biological hazards of complex mixtures of contaminants: A case study in the Maumee River. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 40(4):1098–1122, (2021). https://doi.org/10.1002/etc.4949
Harrill, J., M. Viant, C. Yauk, M. Sachana, T. Gant, S. Auerbach, R. Beger, M. Bouhifd, J. O'Brien, L. Burgoon, F. Caiment, D. Carpi, T. Chen, B. Chorley, J. Colbourne, R. Corvi, L. Debrauwer, C. O'Donovan, T. Ebbels, D. Ekman, F. Faulhammer, L. Gribaldo, G. Hilton, S. Jones, A. Kende, T. Lawson, S. Leite, P. Leonards, M. Luijten, A. Martin, L. Moussa, S. Rudaz, O. Schmitz, T. Sobanski, V. Strauss, M. Vaccari, V. Vijay, R. Weber, A. Williams, A. Williams, R. Thomas, AND M. Whelan. Progress Towards an OECD Reporting Framework for Transcriptomics and Metabolomics in Regulatory Toxicology. REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, 125:105020, (2021). https://doi.org/10.1016/j.yrtph.2021.105020
Zhen, H., Q. Teng, J. Mosley, Tim Collette, Y. Yue, P. Bradley, AND D. Ekman. Untargeted Lipidomics for Determining Cellular and Subcellular Responses in Zebrafish (Danio rerio) Liver Cells Following Exposure to Complex Mixtures in U.S. Streams. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 55(12):8180–8190, (2021). https://doi.org/10.1021/acs.est.1c01132
Mosley, J., M. Evich, I. Ntai, J. Cavallin, Dan Villeneuve, G. Ankley, Tim Collette, AND D. Ekman. Untargeted MSn-based monitoring of glucuronides in fish: Screening complex mixtures for contaminants with biological relevance. 2021 ACS Fall National Meeting & Exposition, Atlanta, GA, August 22 - 26, 2021.
2020
Cavallin, J., J. Beihoffer, B. Blackwell, A. Cole, D. Ekman, R. Hofer, A. Jastrow, J. Kinsey, K. Keteles, J. Parman, D. Winkelman, AND Dan Villeneuve. Effects-Based Monitoring of Bioactive Compounds Associated with Municipal Wastewater Treatment Plant Effluent Discharge to the South Platte River. SETAC North America, Fort Worth, TX, November 15 - 19, 2020. https://doi.org/10.23645/epacomptox.13100378
Mosley, J., M. Evich, I. Ntai, D. Ekman, Dan Villeneuve, G. Ankley, AND Tim Collette. Untargeted MS-based Monitoring of Glucuronides in Fish: Screening Complex Contaminant Mixtures for Biological Relevance. 2020 Sanibel Conference, Captiva Island, FL, January 23 - 26, 2020.
Mosley, J., M. Evich, D. Ekman, J. Cavallin, Dan Villeneuve, G. Ankley, AND Tim Collette. Untargeted MS-based Monitoring of Glucuronides in Fish: Screening Complex Contaminant Mixtures for Biological Relevance (2020 SETAC). 2020 SETAC North America Annual Meeting, Virtual, November 15 - 19, 2020.
2019
Yue, Y., J. Mosley, P. Bradley, J. Cavallin, D. Villeneuve, G. Ankley, D. Ekman, T. Collette, AND Q. Teng. Assessing Environmental Surface Water Exposure by Cell Culture-based Metabolomics (2019 ASMS). 2019 ASMS Conference on Mass Spectrometry and Allied Topics, Atlanta, GA, June 02 - 06, 2019.
Teng, Q., H. Zhen, D. Ekman, AND T. Collette. Assessing the Impact of Wastewater Treatment Plant Effluent on Downstream Drinking Water-Source QualityUsing Cell Culture-Based Metabolomics. 2019 Experimental Nuclear Magnetic Resonance Conference, Pacific Grove, CA, April 07 - 12, 2019.
Teng, Q., H. Zhen, Y. Yue, J. Mosley, D. Ekman, P. Bradley, D. Villeneuve, J. Cavallin, G. Ankley, AND T. Collette. Cell-Based Lipidomics for Assessing Ecological Impacts of Environmental Surface Waters. 2019 SETAC North America Annual Meeting, Toronto, November 03 - 07, 2019.
Collette, T., D. Ekman, H. Zhen, H. Nguyen, P. Bradley, AND Q. Teng. Cell-Based Metabolomics for Untargeted Screening and Prioritization of Vertebrate-Active Stressors in Streams Across the United States. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 53(15):9232-9240, (2019). https://doi.org/10.1021/acs.est.9b02736
Evich, M., J. Mosley, I. Ntai, D. Ekman, AND T. Collette. Developing an Untargeted High-resolution Mass Spectrometry Method for the Detection and Identification of Glucuronide Biotransformation Products in Environmentally Exposed Fish. 2019 American Society for Mass Spectrometry (ASMS), Atlanta, GA, June 02 - 06, 2019.
Cavallin, J., W. Battaglin, J. Beihoffer, B. Blackwell, P. Bradley, A. Cole, D. Ekman, J. Kinsey, K. Keteles, R. Weissinger, D. Winkelman, AND D. Villeneuve. Effects-based monitoring of bioactive contaminants discharged to the Colorado River before and after upgrades to a municipal wastewater treatment facility. SETAC North America, Toronto, ON, CANADA, November 03 - 07, 2019.
Cole, A., J. Cavallin, J. Beihoffer, B. Blackwell, D. Ekman, A. Jastrow, J. Kinsey, K. Keteles, J. Parman, D. Winkelman, AND D. Villeneuve. Evaluating effects of bioactive contaminants associated with waste water treatment plant effluent discharge to the South Platte River. SETAC North America, Toronto, ON, CANADA, November 03 - 07, 2019.
Mosley, J., M. Evich, I. Ntai, D. Ekman, J. Cavallin, D. Villeneuve, G. Ankley, AND T. Collette. High-resolution Mass Spectrometry for Monitoring Physiological Impacts and Biotransformation Products in Fish Exposed to Wastewater Effluent. 2019 ASMS Conference on Mass Spectrometry and Allied Topics, Atlanta, GA, June 02 - 06, 2019.
Viant, M., T. Ebbels, R. Beger, D. Epps, H. Kamp, P. Leonards, G. Loizou, J. MacRae, B. van Ravenzwaay, P. Rocca-Serra, R. Salek, T. Walk, R. Weber, AND D. Ekman. Metabolomics in Regulatory Toxicology: Use Cases, Best Practice and Reporting Standards. 2019 SETAC North America Annual Meeting, Toronto, CANADA, November 03 - 07, 2019.
Viant, M., T. Ebbels, R. Beger, D. Epps, H. Kamp, P. Leonards, G. Loizou, J. MacRae, B. van Ravenzwaay, P. Rocca-Serra, R. Salek, T. Walk, R. Weber, AND D. Ekman. Use cases, best practice and reporting standards for metabolomics in regulatory toxicology. Nature Communications. Nature Publishing Group, London, Uk, 10:3041, (2019). https://doi.org/10.1038/s41467-019-10900-y
2018
Mosley, J., M. Evich, AND D. Ekman. A Novel Method for Nontargeted Analysis of Glucuronides in Biofluids as Indicators of Exposure to Environmental Contaminants. 2018 SETAC NA Annual Meeting, Sacramento, CA, November 04 - 08, 2018.
Zhen, H., D. Ekman, Tim Collette, Dan Villeneuve, G. Ankley, P. Bradley, AND Q. Teng. A cell-culture based lipidomics approach to assess the biological impact of exposure to environmental surface waters. Metabolomics 2018, Seattle, WA, June 24 - 28, 2018.
Yue, Y., J. Mosley, P. Brandley, J. Cavallin, Dan Villeneuve, G. Ankley, D. Ekman, Tim Collette, AND Q. Teng. Assessing Environmental Surface Water Exposure by Cell Culture-based Metabolomics. 2018 SETAC NA Annual Meeting, Sacramento, CA, November 04 - 08, 2018.
Zhen, H., D. Ekman, Tim Collette, S. Glassmeyer, M. Mills, E. Furlong, D. Kolpin, AND Q. Teng. Assessing the impact of wastewater treatment plant effluent on downstream drinking water-source quality using a zebrafish (Danio Rerio) liver cell-based metabolomics approach. WATER RESEARCH. Elsevier Science Ltd, New York, NY, 145:198-209, (2018). https://doi.org/10.1016/j.watres.2018.08.028
Cavallin, J., W. Battaglin, J. Beihoffer, B. Blackwell, P. Bradley, D. Ekman, J. Kinsey, K. Keteles, E. Lai, R. Weissinger, D. Winkelman, AND Dan Villeneuve. Effects-based monitoring of bioactive contaminants associated with exposure to wastewater treatment plant discharge on the Colorado River. SETAC North America, Sacramento, CA, November 04 - 08, 2018.
Cole, A., J. Cavallin, J. Beihoffer, B. Blackwell, D. Ekman, A. Jastrow, J. Kinsey, K. Keteles, J. Parman, D. Winkelman, AND Dan Villeneuve. Evaluating effects of bioactive contaminants related to waste water treatment plant effluent on the South Platte River. SETAC North America, Sacramento, CA, November 04 - 08, 2018.
Ekman, D., K. Keteles, J. Beihoffer, J. Cavallin, K. Dahlin, J. Davis, A. Jastrow, Jim Lazorchak, M. Mills, M. Murphy, D. Nguyen, A. Vajda, Dan Villeneuve, D. Winkelman, AND Tim Collette. Evaluation of targeted and untargeted effects-based monitoring tools to assess impacts of contaminants of emerging concern on fish in the South Platte River, CO. ENVIRONMENTAL POLLUTION. Elsevier Science Ltd, New York, NY, 239:706-713, (2018). https://doi.org/10.1016/j.envpol.2018.04.054
Evich, M., J. Mosley, J. Doering, G. Ankley, K. Fay, Dan Villeneuve, Tim Collette, AND D. Ekman. High-Resolution Mass Spectrometry-based Metabolomics for Translating Exposure Effects Across Species. 2018 SETAC NA Annual Meeting, Sacramento, Ca, November 04 - 08, 2018.
Mosley, J., D. Ekman, J. Cavallin, Dan Villeneuve, G. Ankley, AND Tim Collette. High‐resolution mass spectrometry of skin mucus for monitoring physiological impacts and contaminant biotransformation products in fathead minnows exposed to wastewater effluent. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 37(3):788-796, (2018). https://doi.org/10.1002/etc.4003
Beger, R., M. Viant, T. Ebbels, J. Dorne, D. Ekman, A. Goetz, H. Kamp, P. Leonards, G. Loizou, J. McRae, B. van Ravenzwaay, R. Salek, R. Weber, AND A. White. MEtabolomics standaRds Initiative in Toxicology (MERIT). Metabolomics 2018, Seattle, WA, June 24 - 28, 2018.
Teng, Q., H. Zhen, Y. Yue, J. Mosley, D. Ekman, Dan Villeneuve, J. Cavallin, G. Ankley, AND Tim Collette. Metabolite PAssessing Chemical Exposures and Ecological Impacts of Environmental Surface WatersUsing Cell Culture-based Metabolomics (SETAC 11/04/2018). 2018 SETAC NA Annual Meeting, Sacramento, CA, November 04 - 08, 2018.
Collette, Tim, D. Ekman, P. Bradley, AND Q. Teng. Prioritizing Contaminants in Complex Mixtures Using In vitro-based metabolomics and Multivariate Statistics. 2018 SETAC NA Annual Meeting, Sacramento, CA, November 04 - 08, 2018.
2017
Teng, Q., W. Wang, H. Zhen, D. Ekman, Dan Villeneuve, J. Cavallin, G. Ankley, P. Bradley, AND Tim Collette. Assessing chemical exposure and ecological impacts of environmental surface waters using cell culture-based metabolomic. 2017 SETAC North America Annual Meeting, MN, Minneapolis, November 12 - 16, 2017.
Zhen, H., J. Mosley, D. Ekman, Tim Collette, J. Cavallin, Dan Villeneuve, G. Ankley, P. Bradley, AND Q. Teng. Assessing the biological impact of exposure to environmental surface waters with cell-based lipidomics. 2017 SETAC North America Annual Meeting, Minneapolis, MN, November 12 - 16, 2017.
Martinovic-Weigelt, D., A. Mehinto, G. Ankley, J. Berninger, Tim Collette, J. Davis, N. Denslow, E. Durhan, E. Eid, D. Ekman, K. Jensen, M. Kahl, C. LaLone, Q. Teng, AND Dan Villeneuve. Derivation and evaluation of putative adverse outcome pathways for the effects of cyclooxygenase inhibitors on reproductive processes in female fish. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 156(2):344-361, (2017).
Schoenfuss, H., S. Corsi, D. Ekman, AND Dan Villeneuve. Great Lakes Restoration Initiative: Occurrence and Effects of Contaminants of Emerging Concern. IN: SETAC Globe, SETAC Press, Pensacola, FL, (December):12, (2017).
Mosley, J., D. Ekman, J. Cavallin, Dan Villeneuve, G. Ankley, AND Tim Collette. High-resolution Mass Spectrometry of Skin Mucus for Monitoring Physiological Impacts in Fish Exposed to Wastewater Effluent at a Great Lakes AOC. 2017 SETAC North America Meeting, MN, Minneapolis, November 12 - 16, 2017.
2016
Zhen, H., H. Nguyen, D. Ekman, Tim Collette, S. Glassmeyer, AND Q. Teng. Cell-based metabolomics approach for assessing the impact of wastewater treatment plant effluent on downstream water quality. SETAC North America 37th Annual Meeting, Orlando, FL, November 06 - 10, 2016.
Davis, J., D. Ekman, Q. Teng, G. Ankley, J. Berninger, J. Cavallin, K. Jensen, M. Kahl, A. Schroeder, Dan Villeneuve, Z. Jorgenson, K. Lee, AND Tim Collette. Linking field-based metabolomics and chemical analyses to prioritize contaminants of emerging concern in the Great Lakes basin. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 35(10):2493–2502, (2016).
Collette, Tim, D. Skelton, J. Davis, J. Cavallin, K. Jensen, M. Kahl, G. Ankley, G. Ankley, D. Martinovic-Weigelt, AND D. Ekman. Metabolite profiles of repeatedly sampled urine from male fathead minnows (Pimephales promelas) contain unique lipid signatures following exposure to anti-androgens. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY - PART D: GENOMICS AND PROTEOMICS. Elsevier BV, AMSTERDAM, Netherlands, 19:190-198, (2016).
Nguyen, H., H. Zhen, D. Ekman, Dan Villeneuve, J. Cavallin, G. Ankley, Tim Collette, P. Bradley, AND Q. Teng. Monitoring Ecological Impacts of Environmental Surface Waters using Cell-based Metabolomics. SETAC North America 37th Annual Meeting, Orlando, FL, November 06 - 10, 2016.
Teng, Q., D. Ekman, H. Zhen, Dan Villeneuve, J. Cavallin, J. Davis, G. Ankley, AND Tim Collette. Screening ecological impacts of environmental surface waters using cell-based metabolomics. SETAC North America 37th Annual Meeting, Orlando, FL, November 06 - 10, 2016.
2015
Ekman, D. A Multi-Agency Effort for Assessing the Occurrence and Biological Impacts of CECs in Support of the Great Lakes Restoration Initiative. SETAC North America 36th Annual Meeting, Salt Lake City, UT, November 01 - 05, 2015.
Davis, J., D. Ekman, D. Skelton, C. LaLone, G. Ankley, J. Cavallin, Dan Villeneuve, AND Tim Collette. Applying high resolution mass spectrometry and network analysis to assess exposure to a novel androgen, spironolactone, on metabolic pathways in fish. SETAC North America 36th Annual Meeting, Salt Lake City, UT, November 01 - 06, 2015.
Teng, Q., D. Ekman, Dan Villeneuve, J. Cavallin, J. Davis, G. Ankley, AND Tim Collette. Cell-based metabolomics for assessing chemical exposure and toxicity of environmental surface waters (presentation). Presented at 11th International Conference of the Metabolomics Society, San Francisco, CA, June 29 - July 02, 2015.
Martinovic-Weigelt, D., A. Mehinto, G. Ankley, J. Berninger, T. Colette, J. Davis, N. Denslow, E. Durhan, E. Eid, D. Ekman, K. Jensen, M. Kahl, AND Dan Villeneuve. Conceptualizing adverse outcome pathways for cyclooxygenase inhibitors using transcriptomic and metabolomic characterization. SETAC North America, Salt Lake City, UT, November 01 - 05, 2015.
Martinovic-Weigelt, D., A. Mehinto, G. Ankley, J. Berninger, Tim Collette, J. Davis, N. Denslow, E. Durhan, E. Eid, D. Ekman, K. Jensen, M. Kahl, AND Dan Villeneuve. Derivation and evaluation of adverse outcome pathways for the effects of cyclooxygenase inhibitors on reproductive processes in fish. Canadian Ecotoxicity Workshop Meeting, Saskatoon, SK, CANADA, October 04 - 07, 2015.
Collette, Tim, J. Davis, J. Beihoffer, A. Jastrow, K. Keteles, AND D. Ekman. In Situ Field-Based Metabolomics for Evaluating the Impacts of Exposure to Chemicals of Emerging Concern Relative to Other Stressors. SETAC North America 36th Annual Meeting, Salt Lake City, UT, November 01 - 06, 2015.
Ekman, D., D. Skelton, J. Davis, Dan Villeneuve, J. Cavallin, A. Schroeder, K. Jensen, G. Ankley, AND Tim Collette. Metabolite profiling of fish skin mucus: a novel approach for minimally-invasive environmental exposure monitoring and surveillance. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 49(5):3091-3100, (2015).
Simmons, D., J. Benskin, J. Cosgrove, B. Duncker, D. Ekman, C. Martyniuk, AND J. Sherry. Omics for aquatic ecotoxicology: Control of extraneous variability to enhance the analysis of environmental effects. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 34(8):1693-1704, (2015).
2014
Teng, Q., D. Ekman, Dan Villeneuve, J. Cavallin, J. Davis, G. Ankley, AND Tim Collette. Cell-based Metabolomics for Assessing Chemical Exposure and Toxicity of Environmental Surface Waters. SETAC North America 35th Annual Meeting, Vancouver, BC, CANADA, November 10 - 13, 2014.
Ekman, D., J. Beihoffer, G. Ankley, J. Cavallin, J. Davis, K. Jensen, M. Kahl, K. Keteles, D. Skelton, Q. Teng, Dan Villeneuve, AND Tim Collette. Field-based Metabolomics for Assessing Contaminated Surface Waters. Aquatic Toxicity Workshop, Ottawa, ON, CANADA, September 29 - October 01, 2014.
Ekman, D. Impacts of WWTP Effluents on the Hepatic Metabolome of Male and Female Fathead Minnows in the South Platte River, Colorado. SETAC North America 35th Annual Meeting, Vancouver, BC, CANADA, November 09 - 13, 2014.
Garcia-Reyero, N., D. Ekman, T. Habib, Dan Villeneuve, Tim Collette, D. Bencic, G. Ankley, AND E. Perkins. Integrated approach to explore the mechanisms of aromatase inhibition and recovery in fathead minnows (Pimephales promelas). GENERAL AND COMPARATIVE ENDOCRINOLOGY. Academic Press Incorporated, Orlando, FL, 203:193-202, (2014).
Davis, J., D. Ekman, Q. Teng, G. Ankley, J. Berninger, J. Cavallin, K. Jensen, M. Kahl, A. Schroeder, Dan Villeneuve, Z. Jorgenson, K. Lee, AND Tim Collette. Linking field-based metabolomics and chemical analyses to identify contaminants of emerging concern in the Great Lakes ecosystem. SETAC North America 35th Annual Meeting, Vancouver, BC, CANADA, November 09 - 13, 2014.
Ekman, D. Metabolomics in Aquatic Ecosystem Health Assessments. SETAC North America 35th Annual Meeting, Vancouver, CANADA, November 10 - 13, 2014.
2013
Ekman, D., G. Ankley, V. Blazer, Tim Collette, N. Garcia-Reyero, L. Iwanowicz, Z. Jorgenson, K. Lee, P. Mazik, D. Miller, E. Perkins, E. Smith, J. Tietge, AND Dan Villeneuve. Biological Effects–Based Tools for Monitoring Impacted Surface Waters in the Great Lakes: A Multiagency Program in Support of the Great Lakes Restoration Initiative. ENVIRONMENTAL PRACTICE. Oxford University Press, Cary, NC, 15(4):409-426, (2013).
Teng, Q., D. Ekman, Dan Villeneuve, J. Cavallin, D. Skelton, G. Ankley, AND Tim Collette. Cell-based Metabolomics for Monitoring Ecological Impacts of Environmental Surface Waters. Presented at 34th Annual Meeting SETAC North America, Nashville, TN, November 17 - 21, 2013.
Davis, J., Tim Collette, Dan Villeneuve, J. Cavallin, Q. Teng, K. Jensen, M. Kahl, J. Mayasich, G. Ankley, AND D. Ekman. Field-Based Approach for Assessing the Impact of Treated Pulp and Paper Mill Effluent on Endogenous Metabolites of Fathead Minnows (Pimephales promelas). ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 47(18):10628-10636, (2013).
Collette, Tim, G. Ankley, J. Cavallin, E. Durhan, K. Jensen, M. Kahl, L. Makynen, D. Skelton, Q. Teng, Dan Villeneuve, AND D. Ekman. Field-deployed Metabolomics for Assessing Waters Impacted by Point and Non-Point Sources of Contamination. Presented at 34th Annual SETAC North America, Nashville, TN, November 17 - 21, 2013.
TENG, Q., D. R. EKMAN, W. Huang, AND T. W. COLLETTE. Impacts of 17α-ethynylestradiol exposure on metabolite profiles of zebrafish (Danio rerio) liver cells. AQUATIC TOXICOLOGY. Elsevier Science Ltd, New York, NY, 130-131:184-191, (2013).
Skelton, D., D. Ekman, D. Martinovic-Weigelt, G. Ankley, Dan Villeneuve, Q. Teng, AND Tim Collette. Metabolomics for in situ environmental monitoring of surface waters impacted by contaminants from both point and non-point sources. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, , online, (2013).
Ekman, D., G. Ankley, J. Cavallin, J. Davis, E. Durhan, K. Jensen, M. Kahl, L. Makynen, D. Skelton, Q. Teng, Dan Villeneuve, AND Tim Collette. Metabolomics from the Lab to the Field: Lessons Learned Along the Way. Presented at 34th Annual SETAC North America, Nashville, TN, November 17 - 21, 2013.
Ramirez, T., M. Daneshian, H. Kamp, F. Bois, M. Clench, M. Coen, B. Donley, S. Fischer, D. Ekman, E. Fabian, C. Guillou, J. Heuer, H. Hogberg, H. Jungnickel, H. Keun, G. Krennrich, E. Krupp, A. Luch, F. Noor, E. Peter, B. Riefke, M. Seymour, N. Skinner, L. Smirnova, E. Verheij, S. Wagner, T. Hartung, B. van Ravenzwaay, AND M. Leist. Metabolomics in Toxicology and Preclinical Research, a t4 Workshop Report. ALTEX. Society ALTEX Edition, Kuesnacht, Switzerland, 30(2):209-225, (2013).
Ankley, G., J. Berninger, J. Cavallin, E. Eid, E. Durhan, K. Jensen, M. Kahl, C. LaLone, L. Makynen, M. Severson, K. Stevens, Tim Collette, D. Ekman, E. Perkins, AND N. Garcia-Reyero. Novel effects-based monitoring approaches to evaluate chemicals of emerging concern in Great Lakes areas of concern. Presented at International Association of Great Lakes Research, West Lafayette, IN, June 02 - 06, 2013.
Ankley, G., J. Berninger, J. Cavallin, E. Eid, E. Durhan, K. Jensen, M. Kahl, C. LaLone, L. Makynen, M. Severson, K. Stevens, Dan Villeneuve, Tim Collette, D. Ekman, E. Perkins, AND N. Garcia-Reyero. Novel effects-based monitoring approaches to evaluate chemicals of emerging concern in the St. Louis River estuary. Presented at St. Louis River Estuary Summit, February 26 - 27, 2013.
Garcia-Reyero, N., Dan Villeneuve, L. Escalon, T. Habib, D. Ekman, E. Durhan, M. Kahl, K. Jensen, J. Cavallin, J. Berninger, Tim Collette, G. Ankley, AND E. Perkins. Pathway-based monitoring of biological effects at Great Lakes sites (Presntation). Presented at International Association of Great Lakes Research, West Lafayette, IN, June 02 - 06, 2013.
Skelton, D., Tim Collette, C. LaLone, G. Ankley, Dan Villeneuve, AND D. Ekman. Urine-based Metabolomics with Fish: Use of Repeat Sampling (of an individual) to Non-lethally Assess Temporal Effects of Contaminants. Presented at 34th Annual SETAC North America, Nashville, TN, November 17 - 21, 2013.
2012
Davis, J., Tim Collette, D. Ekman, G. Ankley, J. Cavallin, K. Jensen, M. Kahl, AND D. Villeneuve. A field-based approach for assessing the impact of paper pulp mill effluent on the metbolite profile of fathead minnows (Pimephales promelas). Presented at SETAC North America 33rd Annual Meeting, Long Beach, CA, November 11 - 15, 2012.
Skelton, D., Tim Collette, D. Martinovic-Weigelt, G. Ankley, D. Villeneuve, AND D. Ekman. Characterizing Exposures of Fish to Wastewater Treatment Plant Effluent: An Integrated Metabolite and Lipid Profiling Approach. Presented at SETAC 33rd North American Annual Meeting, Long Beach, CA, November 11 - 15, 2012.
EKMAN, D. R., P. C. HARTIG, M. C. CARDON, D. M. SKELTON, Q. TENG, E. J. DURHAN, K. M. JENSEN, M. D. KAHL, DAN VILLENEUVE, L. E. GRAY, T. W. COLLETTE, AND G. T. ANKLEY. Metabolite Profiling and a Transcriptional Activation Assay Provide Direct Evidence of Androgen Receptor Antagonism by Bisphenol A in Fish. ENVIRONMENTAL SCIENCE AND TECHNOLOGY. John Wiley & Sons, Ltd., Indianapolis, IN, 46(17):9673-9680, (2012).
Collette, Tim, G. Ankley, E. Durhan, K. Jensen, M. Kahl, K. Lee, L. Makynen, D. Skelton, L. Thomas, Q. Teng, A. Trowbridge, D. Villeneuve, AND D. Ekman. Metabolomic Approaches for Characterizing Aquatic Ecosystems. Presented at SETAC North America 33rd Annual Meeting, Long Beach, CA, November 11 - 15, 2012.
Teng, Q., D. Ekman, AND Tim Collette. Push-through Direction Injectin NMR Automation. Presented at 8th Annual International Meeting of the Metabolomics Society, Washington, DC, June 25 - 28, 2012.
TENG, Q., D. R. EKMAN, H. Wenlin, AND T. W. COLLETTE. Push-through direct injection NMR: an optimized automation method applied to metabolomics. ANALYST. Royal Society of Chemistry, Cambridge, Uk, 137(9):2226-2232, (2012).
EKMAN, D. R. Role of Metabolomics in Environmental Chemical Exposure and Risk Assessment. Presented at Metabolomics in Toxicological and Pre Clinical Research, Berlin, GERMANY, February 13 - 15, 2012.
Ekman, D., DAN VILLENEUVE, Z. Jorgenson, K. Lee, D. M. SKELTON, Q. TENG, E. J. DURHAN, K. M. JENSEN, M. D. KAHL, J. CAVALLIN, G. T. ANKLEY, AND T. W. COLLETTE. Taking Metabolomics to the Field: A Pilot Study in a Great Lakes Area of Concern (AOC). Presented at SETAC 33rd North America Annual Meeting, Long Beach, CA, November 11 - 15, 2012.
2011
KAHL, M. D., G. T. ANKLEY, T. W. COLLETTE, E. J. DURHAN, D. R. EKMAN, K. M. JENSEN, K. LEE, E. A. MAKYNEN, L. THOMAS, A. TROWBRIDGE, AND DAN VILLENEUVE. Caged Fish Studies to Detect and Monitor Contaminants of Emerging Concern in the Great Lakes. Presented at Society of Environmental Toxicology and Chemistry (SETAC), Boston, MA, November 13 - 17, 2011.
TENG, Q., D. R. EKMAN, AND T. W. COLLETTE. Cell-based Metabolomics: A New Tool to Assess Environmental Exposure and Toxicity. Presented at SETAC North America 32nd Annual Meeting, Boston, MA, November 13 - 17, 2011.
VILLENEUVE, DAN, G. T. ANKLEY, D. C. BENCIC, J. M. LAZORCHAK, T. W. COLLETTE, D. R. EKMAN, S. W. EDWARDS, N. GARCIA-REYERO, AND E. J. PERKINS. Experimental Approaches to Systematic Discovery and Development of Reproductive Adverse Outcome Pathways in Fish. Presented at Society of Environmental Toxicology and Chemistry, Boston, MA, November 13 - 17, 2011.
EKMAN, D. R., DAN L. VILLENEUVE, Q. TENG, K. J. Ralston-Hooper, D. Martinovic-Weigelt, M. D. KAHL, K. M. JENSEN, E. J. DURHAN, E. A. MAKYNEN, G. T. ANKLEY, AND T. W. COLLETTE. Use of Gene Expression, Biochemical and Metabolite Profiles to Enhance Exposure and Effects Assessment of the Model Androgen 17β-trenbolone in Fish. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 30(2):319-329, (2011).
2010
COLLETTE, T. W., Q. TENG, K. M. JENSEN, M. D. KAHL, E. A. MAKYNEN, E. J. DURHAN, DAN VILLENEUVE, D. MARTINOVIC, N. D. Mueller, G. T. ANKLEY, AND D. R. EKMAN. Impacts of an Anti-Androgen and an Adrogen/Anti-Androgen Mixture on the Metabolite Profile of Male Fathead Minnow Urine. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 44(17):6881-6886, (2010).
COLLETTE, T. W., Q. TENG, K. M. JENSEN, M. D. KAHL, E. A. MAKYNEN, E. J. DURHAN, DAN VILLENEUVE, D. MARTINOVIC-WEIGELT, G. T. ANKLEY, AND D. R. EKMAN. Impacts of an Anti-androgen and an Androgen/anti-androgen Mixture on the Metabolite Profile of Male Fathead Minnow Urine. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 44(17):6881-6886, (2010).
KENNEKE, J. F., D. R. EKMAN, C. S. MAZUR, B. J. Konwick, A. T. Fisk, J. K. AVANTS, AND A. W. GARRISON. Integration of Metabolomics and In vitro Metabolism Assays for Investigating the Stereoselective Transformation of Triadimefon in Rainbow Trout. Chirality. Wiley InterScience, Silver Spring, MD, 22(2):183-192, (2010).
HENDERSON, W. M., T. W. COLLETTE, D. J. DIX, AND D. R. EKMAN. Multi-Platform Metabolomic Analyses of Rat Urine Following Exposure to Perfluorinated Chemicals (PFCs). Presented at 49th Annual Society of Toxicology Meeting, Salt Lake City, UT, March 07 - 11, 2010.