||Malathion Exposure Studies. Determination of Mono- and Dicarboxylic Acids and Alkyl Phosphates in Urine.
Bradway, Diane E. ;
Shafik., Talaat M. ;
||Health Effects Research Lab., Research Triangle Park, N.C.
Carboxylic acids ;
Phosphorus organic compounds ;
Chemical analysis ;
Body fluids ;
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A method for the analysis of the dialkyl phosphate metabolites of organophosphorus pesticides was modified to permit analysis of the monocarboxylic acid (MCA) and dicarboxylic acid (DCA) metabolites of malathion. Recoveries of MCA and DCA from spiked urine are presented, as well as the results of analyses of urine from rats exposed to malathion at five levels. Data from both exposed and unexposed humans are presented. (Copyright (c) by the American Chemical Society, 1977.)