| Document Number: 1 |
Full Record |
| Main Title |
Genotoxicity of Inhibitors of DNA Topoisomerases I (Camptothecin) and II (m-AMSA) In vivo and In vitro. |
| Author |
Backer, L. C. ;
Allen, J. W. ;
Harrington-Brock, K. ;
Campbell, J. A. ;
DeMarini, D. M. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. Genetic Toxicology Div. ;Environmental Health Research and Testing, Inc., Research Triangle Park, NC. |
| Publisher |
c1990 |
| Year Published |
1990 |
| Report Number |
EPA/600/J-90/421; |
| Stock Number |
PB91-171769 |
| Additional Subjects |
Enzyme inhibitors ;
Mutagens ;
Camptothecin ;
Amsacrine ;
DNA topoisomerase I ;
DNA damage ;
Mutagenicity tests ;
In vitro analysis ;
In vivo analysis ;
Lymphoma ;
Chromosome aberrations ;
Cell cycle ;
Thymidine linase ;
Cultured tumor cells ;
Adenosine cyclic monophosphate ;
Reprints ;
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB91-171769 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
9p |
|
| Document Number: 2 |
Full Record |
| Main Title |
Morphological Transformation and Chromosome Damage by Amsacrine in C3H/10T(1/2) Clone 8 Cells. |
| Author |
Ferguson, L. R. ;
Van Zijl, P. ;
Nesnow, S. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. ;Auckland Univ. (New Zealand). |
| Year Published |
1986 |
| Report Number |
EPA/600/J-86/375; |
| Stock Number |
PB87-203147 |
| Additional Subjects |
Morphology ;
Cells(Biology) ;
Chemotherapy ;
Carcinogens ;
Drug therapy ;
Mutations ;
Reprints ;
Amsacrine(4'-(9-acridinylamino)methanesulfon-m-anisidide) ;
Chromosome abnormalities ;
Cell survival
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB87-203147 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
13p |
|
| Document Number: 3 |
Full Record |
| Main Title |
Polyploidy Induction as a Consequence of Topoisomerase Inhibition. A Flow Cytometric Assessment. |
| Author |
Zucker, R. M. ;
Adams, D. J. ;
Bair, K. W. ;
Elstein, K. H. ;
|
| CORP Author |
ManTech Environmental Technology, Inc., Research Triangle Park, NC. ;Northrop Services, Inc., Research Triangle Park, NC. ;Burroughs Wellcome Co., Research Triangle Park, NC.;Health Effects Research Lab., Research Triangle Park, NC. |
| Publisher |
cNov 91 |
| Year Published |
1991 |
| Report Number |
EPA-68-02-4450; EPA/600/J-91/014; |
| Stock Number |
PB92-143866 |
| Additional Subjects |
DNA topoisomerase II ;
Enzyme inhibitors ;
Ploidies ;
Doxorubicin ;
Teniposide ;
Amsacrine ;
Acute erythroblastic leukemia ;
Cell cycle ;
Dose-response relationships ;
Deoxyribonucleic acids ;
Fluorescence ;
Mitosis ;
Reprints ;
Crisnatol
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB92-143866 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
12p |
|
| Document Number: 4 |
Full Record |
| Main Title |
Synaptonemal Complex Damage as a Measure of Genotoxicity at Meiosis. |
| Author |
Allen, J. W. ;
Poorman, P. A. ;
Backer, L. C. ;
Gibson, J. B. ;
Westbrook-Collins, B. ;
|
| CORP Author |
Burroughs Wellcome Co., Research Triangle Park, NC. ;Environmental Health Research and Testing, Inc., Research Triangle Park, NC. ;Duke Univ. Medical Center, Durham, NC.;Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1988 |
| Report Number |
EPA-R-812736; EPA/600/D-88/136; |
| Stock Number |
PB88-223789 |
| Additional Subjects |
Toxicity ;
Genes ;
Meiosis ;
Cell division ;
Chromosomes ;
Mitomycins ;
Cyclophosphamide ;
Colchicine ;
Vinblastine ;
Laboratory animals ;
Mice ;
Chromosomal aberrations ;
Genetic disorders ;
Genotoxicity ;
Duplication(Genes) ;
Amsacrine ;
Ellipticines ;
Cisplatin ;
Chromosome damage ;
Synaptonemal complex
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB88-223789 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
17p |
|
| Document Number: 5 |
Full Record |
| Main Title |
Synaptonemal Complex Damage Induced by Clastogenic and Anti-Mitotic Chemicals: Implications for Non-Disjunction and Aneuploidy (Journal Version). |
| Author |
Allen, J. W. ;
Gibson, J. B. ;
Poorman, P. A. ;
Backer, L. C. ;
Moses, M. J. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. Genetic Toxicology Div. ;Duke Univ. Medical Center, Durham, NC. ;Wellcome Research Labs., Research Triangle Park, NC. |
| Publisher |
c1988 |
| Year Published |
1988 |
| Report Number |
EPA/600/J-88/205; |
| Stock Number |
PB89-144471 |
| Additional Subjects |
Mutagens ;
Toxicology ;
Synopses ;
Mice ;
Laboratory animals ;
Exposure ;
Meiosis ;
Mitomycins ;
Cyclophosphamide ;
Colchicine ;
Chromosome abnormalities ;
Reprints ;
Aneuploidy ;
Chromosomal translocation ;
Genetic effects ;
Mitomycin C ;
Amsacrine ;
Vinblastine sulfate ;
Prophase ;
Alkylating agents ;
Chromosome breakage ;
Toxic substances ;
Sister chromatid exchanges ;
Antimitotic drugs
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB89-144471 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
14p |
|
