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Grantee Research Project Results

EPA/NIEHS Children's Environmental Health and Disease Prevention Research Centers (CEHCs) - 2010

The first eight Centers were established in 1998 to study the effects of environmental factors, such as pesticides and air pollution, on childhood asthma and children’s growth and development. Four more Centers were established in 2001 to study the basis of neurodevelopmental and behavioral disorders such as autism. Additional Centers were established in 2004 and 2007 to investigate how exposure to mixtures of chemicals affect children’s health and to study environmentally driven disparities in birth outcomes. Additional centers were established in 2010 to (1) capitalize on the research findings and resources from ongoing epidemiology and clinical studies of pregnant women and children; (2) enhance the dynamic application of novel findings and approaches in areas of basic or mechanistic research e.g., imaging, epigenetics and comparative biology to human studies; (3) develop and apply new or improved biomarkers to best characterize exposure effects on human biology and to predict long-term clinical consequences; (4) train new investigators who can address emerging issues in children's environmental health with state of the art tools and methodologies; and (5) ensure active participation of the identified stakeholders in the research process and translation of research findings; (5) identify the influences of environmental exposures on normal physiological function of organs and systems of the fetus/child during gestation and/or early childhood; (6) determine the mechanisms of vulnerability to environmental stressors of the developing fetus and young child at all stages of early development; and (7) understand the impact of the complex environment on children's health including chemicals, diet and nutrition, physical activity, and psychosocial factors on children's health, from birth through young adulthood. Nutrition, social and cultural factors cannot be considered alone, but they can be included as secondary or modifier variables to the primary environmental stressor. Each Center fosters community participation in one or more studies.

For more detailed information, consult the CEHC Website: https://www.epa.gov/ncer/childrenscenters

  • Environmental Determinants of Airway Disease in Children
  • Novel Methods to Assess Effects of Bisphenol A & Phthalates on Child Development
  • Dartmouth College
  • University of Washington Center for Child Environmental Health Risks Research (2010)
  • Formative Center for the Evaluation of Environmental Impacts on Fetal Development
  • University of California, San Francisco
  • UC Berkeley Stanford Childrens Environment Health Center
  • University of Michigan
  • Center for Integrative Research on Childhood Leukemia and the Environment (CIRCLE)
  • Johns Hopkins University
  • UC Berkeley School of Public Health: CHAMACOS Office, Berkeley, CA

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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Last updated April 28, 2023
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