Grantee Research Project Results
Selected Publications Details for Grant Number R834998
Model of Toxicant Response in Engineered Liver
RFA:
Computational Toxicology: Biologically-Based Multi-Scale Modeling (2010)
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| Reference Type | Citation | Progress Report Year | Document Sources |
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| Book Chapter | Cassin ME, Rajagopalan P. Polyelectrolyte multilayers for applications in hepatic tissue engineering. In: Picart C, Caruso F, Voegl J-C, eds. Layer-by-Layer Films for Biomedical Applications. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co., 2015, Chapter 22, pp. 487-506. |
R834998 (2013) R834998 (Final) |
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| Journal Article | Bharadwaj A, Singh D, Ritz A, Tegge A, Poirel C, Kraivkivski P, Adames N, Luther K, Kale S, Peccoud J, Tyson T, Murali T. GraphSpace: stimulating interdisciplinary collaborations in network biology. BIOINFORMATICS 2017;33(19):3134-3436 |
R834998 (2013) |
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| Journal Article | Larkin AL, Rodrigues RR, Murali TM, Rajagopalan P. Designing a multicellular organotypic 3D liver model with a detachable, nanoscale polymeric Space of Disse. Tissue Engineering Part C: Methods 2013;19(11):875-884. |
R834998 (2012) R834998 (2013) R834998 (Final) |
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| Journal Article | Lasher CD, Rajagopalan P, Murali TM. Summarizing cellular responses as biological process networks. BMC Systems Biology 2013;7:68. |
R834998 (2012) R834998 (2013) R834998 (Final) |
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| Journal Article | Rajagopalan P, Kasif S, Murali TM. Systems biology characterization of engineered tissues. Annual Review of Biomedical Engineering 2013;15:55-70. |
R834998 (2012) R834998 (2013) R834998 (Final) |
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| Journal Article | Rita A, Poirel C, Tegge A, Sharp N, Simmons K, Powell A, Kale S, Murali T. Pathways on demand: automated reconstruction of human signaling networks. SYSTEMS BIOLOGY AND APPLICATIONS 2016;2(16002) |
R834998 (2013) R834998 (Final) |
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| Journal Article | Sam SA, Teel J, Tegge AN, Bharadwaj A, Murali TM. XTalkDB: a database of signaling pathway crosstalk. Nucleic Acids Research 2017;45(D1):D432-D439. |
R834998 (2013) |
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| Journal Article | Tegge AN, Sharp N, Murali TM. XTALK: a path-based approach for identifying crosstalk between signaling pathways. Bioinformatics 2016;32(2):242-251. |
R834998 (2013) R834998 (Final) |
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| Journal Article | Tegge A, Rodrigues R, Larkin A, Murali T, Pagagopalan P. Transcriptomic Analysis of Hepatic Cells in Multicellular Organotypic Liver Models. NATURE 2018;8(11306) |
R834998 (2013) |
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| Journal Article | Vu LT, Less RR, Rajagopalan P. The promise of organotypic hepatic and gastrointestinal models. Trends in Biotechnology 2014;32(8):406-413. |
R834998 (2013) R834998 (Final) |
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| Journal Article | Vu L, Orbach S, Ray W, Cassin ME, Rajagopalan P, Helm R. The hepatocyte proteome in organotypic rat liver models and the influence of the local microenvironment. PROTEOME SCIENCE 2017;15(12) |
R834998 (2013) R834998 (Final) |
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| Journal Article | Orbach SM, Cassin ME, Ehrich MF, Rajagopalan P. Investigating acetaminophen hepatotoxicity in multi-cellular organotypic liver models. Toxicology in Vitro 2017;42:10-20. |
R834998 (Final) |
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| Journal Article | Orbach SM, Ehrich MF, Rajagopalan P. High-throughput toxicity testing of chemicals and mixtures in organotypic multi-cellular cultures of primary human hepatic cells. Toxicology in Vitro 2018;51:83-94. |
R834998 (Final) |
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| Journal Article | Tegge AN, Rodrigues RR, Larkin AL, Vu L, Murali TM, Rajagopalan P. Transcriptomic analysis of hepatic cells in multicellular organotypic liver models. Scientific Reports 2018;8(1):11306. |
R834998 (Final) |
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.