Grantee Research Project Results
Selected Publications Details for Grant Number R831709C001
Molecular Mechanisms of Pesticide-Induced Developmental Toxicity
RFA:
Centers for Children's Environmental Health and Disease Prevention Research (2003)
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Reference Type | Citation | Progress Report Year | Document Sources |
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Book Chapter | Faustman EM, Gohlke JM, Ponce RA, Lewandowski TA, Seeley MR, Whittaker SG, Griffith WC. Experimental approaches to evaluate mechanisms of developmental toxicity. In: Hood RD, ed. Developmental and Reproductive Toxicology: A Practical Approach, 2nd edition. Boca Raton, FL: CRC Press, Inc., 2005, Chapter 2, pp. 15-60. |
R831709 (2005) R831709 (2007) R831709C001 (2004) |
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Journal Article | Caughlan A, Newhouse K, Namgung U, Xia Z. Chlorpyrifos induces apoptosis in rat cortical neurons that is regulated by a balance between p38 and ERK/JNK MAP kinases. Toxicological Sciences 2004;78(1):125-134. |
R831709 (2007) R831709C001 (2004) |
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Journal Article | Costa LG. Current issues in organophosphate toxicology. Clinica Chimica Acta 2006;366(1-2):1-13. |
R831709 (2005) R831709 (2006) R831709 (2007) R831709C001 (2006) |
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Journal Article | Costa LG, Cole TB, Furlong CE. Gene-environment interactions:paraoxonase (PON1) and sensitivity to organophosphate toxicity. LabMedicine 2006;37(2):109-113. |
R831709 (2005) R831709 (2007) R831709C001 (2007) R831709C002 (2007) |
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Journal Article | Costa LG, Giordano G, Guizzetti M, Vitalone A. Neurotoxicity of pesticides: a brief review. Frontiers in Bioscience 2008;13(4):1240-1249. |
R831709 (2005) R831709 (2007) R831709C001 (2007) R831709C002 (2007) |
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Journal Article | Daston G, Faustman E, Ginsberg G, Fenner-Crisp P, Olin S, Sonawane B, Bruckner J, Breslin W, McLaughlin TJ. A framework for assessing risks to children from exposure to environmental agents. Environmental Health Perspectives 2004;112(2):238-256. |
R831709 (2007) R831709C001 (2004) |
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Journal Article | Eskenazi B, Gladstone EA, Berkowitz GS, Drew CH, Faustman EM, Holland NT, Lanphear B, Meisel SJ, Perera FP, Rauh VA, Sweeney A, Whyatt RM, Yolton K. Methodologic and logistic issues in conducting longitudinal birth cohort studies: lessons learned from the Centers for Children's Environmental Health and Disease Prevention Research. Environmental Health Perspectives 2005;113(10):1419-1429. |
R827027 (2002) R829389 (2003) R829389 (2004) R829389 (2005) R829389 (Final) R829390 (2005) R829390 (Final) R829390C002 (2005) R831709 (2005) R831709C001 (2004) R831710 (2005) R831710 (Final) R831710C001 (2006) R831710C002 (2006) R831711 (2005) R831711 (2006) R831711 (2007) R831711 (Final) R831711C001 (2006) R831711C002 (2004) R831711C002 (2006) R831711C003 (2006) R832141 (2005) R832141 (2007) R832141 (Final) |
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Journal Article | Faustman EM, Gohlke J, Judd NL, Lewandowski TA, Bartell SM, Griffith WC. Modeling developmental processes in animals:applications in neurodevelopmental toxicology. Environmental Toxicology and Pharmacology 2005;19(3):615-624. |
R831709 (2005) R831709 (2006) R831709 (2007) R831709C001 (2004) R831709C001 (2005) R831709C001 (2006) |
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Journal Article | Giordano G, Afsharinejad Z, Guizzetti M, Vitalone A, Kavanagh TJ, Costa LG. Organophosphorus insecticides chlorpyrifos and diazinon and oxidative stress in neuronal cells in a genetic model of glutathione deficiency. Toxicology and Applied Pharmacology 2007;219(2-3):181-189. |
R831709 (2005) R831709 (2006) R831709 (2007) R831709C001 (2006) R831709C001 (2007) R831709C002 (2007) |
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Journal Article | Gohlke JM, Griffith WC, Faustman EM. The role of cell death during neocortical neurogenesis and synaptogenesis:implications from a computational model for the rat and mouse. Developmental Brain Research 2004;151(1-2):43-54. |
R831709 (2005) R831709 (2007) R831709C001 (2004) |
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Journal Article | Gohlke JM, Griffith WC, Faustman EM. A systems-based computational model for dose-response comparisons of two mode of action hypotheses for ethanol-induced neurodevelopmental toxicity. Toxicological Sciences 2005;86(2):470-484. |
R831709 (2004) R831709 (2005) R831709 (2007) R831709C001 (2005) |
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Journal Article | Gribble EJ, Hong SW, Faustman EM. The magnitude of methylmercury-induced cytotoxicity and cell cycle arrest is p53-dependent. Birth Defects Research Part A:Clinical and Molecular Teratology 2005;73(1):29-38. |
R831709 (2005) R831709 (2007) R831709C001 (2004) |
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Journal Article | Guizzetti M, Pathak S, Giordano G, Costa LG. Effect of organophosphorus insecticides and their metabolites on astroglial cell proliferation. Toxicology 2005;215(3):182-190. |
R831709 (2005) R831709 (2006) R831709 (2007) R831709C001 (2005) R831709C001 (2006) R831709C002 (2006) |
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Journal Article | Lewandowski TA, Ponce RA, Charleston JS, Hong S, Faustman EM. Changes in cell cycle parameters and cell number in the rat midbrain during organogenesis. Developmental Brain Research 2003;141(1-2):117-128. |
R831709 (2005) R831709 (2007) R831709C001 (2004) |
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Journal Article | Lewandowski TA, Ponce RA, Charleston JS, Hong S, Faustman EM. Effect of methylmercury on midbrain cell proliferation during organogenesis:potential cross-species differences and implications for risk assessment. Toxicological Sciences 2003;75(1):124-133. |
R831709 (2005) R831709 (2007) R831709C001 (2004) |
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Journal Article | Sidhu JS, Ponce RA, Vredevoogd MA, Yu X, Gribble E, Hong S-W, Schneider E, Faustman EM. Cell cycle inhibition by sodium arsenite in primary embryonic rat midbrain neuroepithelial cells. Toxicological Sciences 2006;89(2):475-484. |
R831709 (2005) R831709 (2006) R831709 (2007) R831709C001 (2005) R831709C001 (2006) |
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Journal Article | Yu X, Griffith WC, Hanspers K, Dillman III JF, Ong H, Vredevoogd MA, Faustman EM. A system-based approach to interpret dose-and time-dependent microarray data:quantitative integration of gene ontology analysis for risk assessment. Toxicological Sciences 2006;92(2):560-577. |
R831709 (2005) R831709 (2006) R831709 (2007) R831709C001 (2006) R832733 (2007) |
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.