Grantee Research Project Results
Selected Publications Details for Grant Number R838300
The Multi-Ethnic Study of Atherosclerosis and Air Pollution (MESA Air):Next Stage
RFA:
Long-term Exposure to Air Pollution and Development of Cardiovascular Disease (2016)
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Reference Type | Citation | Progress Report Year | Document Sources |
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Journal Article | Adar SD, Chen YH, D'Souza JC, O'Neill MS, Szpiro AA, Auchincloss AH, Park SK, Daviglus ML, Diez Roux AV, Kaufman JD. Longitudinal analysis of long-term air pollution levels and blood pressure:a cautionary tale from the Multi-Ethnic Study of Atherosclerosis. Environmental Health Perspectives 2018;126(10):107003 (11 pp.). |
R838300 (2018) R838300 (2020) |
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Journal Article | Bi J, Carmona N, Blanco M, Gassett A, Seto E, Szpiro A, Larson V, Sampson P, Kauffman J, Sheppard L. Publicly available low-cost sensor measurements for PM2.5 exposure modeling:Guidance for monitor deployment and data selection. ENVIRONMENTAL INTERNATIONAL 2022;158(106897). |
R831697 (Final) R838300 (2021) |
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Journal Article | Gronlund CJ, Sheppard L, Adar SD, O'Neill MS, Auchincloss A, Madrigano J, Kaufman J, Diez Roux AV. Vulnerability to the cardiovascular effects of ambient heat in six US cities:Results from the Multi-Ethnic Study of Atherosclerosis (MESA). Epidemiology 2018;29(6):756-764. |
R838300 (2018) R838300 (2020) |
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Journal Article | Hayes RB, Lim C, Zhang Y, Cromar K, Shao Y, Reynolds HR, Silverman DT, Jones RR, Park Y, Jerrett M, Ahn J. PM2.5 air pollution and cause-specific cardiovascular disease mortality. International Journal of Epidemiology 2019. . |
R838300 (2019) R838300 (2020) |
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Journal Article | Higbee D, Liri A, Hamilton F, Granell R, Wyss A, London S, Bartz T, Gharib S, Cho M, Wan E, Silverman E, Crapo J, Lominchar J, Hansen T, Grarup N, Dantoft T, Karhus L, Linneberg A, O'Connor G, Dupis J, Xu H, DeVries M, Hu X, Rich S, Barr R, Manichaikul A, Wijnat S, Brusselle G, Lahousse L, Li X, Cordero A, Obeidat M, Sin D, Harris S, Redmond P, Taylor A, Cox S, Williams A, Shrine N, John C, Guyatt A, Hall I, Smith G, Tobin M, Dodd J. Genome-wide association study of preserved ratio impaired spirometry (PRISm). EUROPEAN RESPIRATORY JOURNAL 2024;63(1):2300337. |
R831697 (Final) R838300 (Final) |
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Journal Article | Keller JP, Larson TV, Austin E, Barr RG, Sheppard L, Vedal S, Kaufman JD, Szpiro AA. Pollutant composition modification of the effect of air pollution on progression of coronary artery calcium:the Multi-Ethnic Study of Atherosclerosis. Environmental Epidemiology 2018;2:e024. |
R834796 (Final) R834796C005 (Final) R838300 (2018) R838300 (2020) |
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Journal Article | Kirwa K, Eckert C, Vedal S, Hajat A, Kaufman J. Ambient air pollution and risk of respiratory infection among adults:evidence from the multiethnic study of atherosclerosis MESA. BMJ OPEN RESPIRATORY RESEARCH 2021;17(10):2075-2083. |
R831697 (Final) R838300 (2021) |
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Journal Article | Lim CC, Hayes RB, Ahn J, Shao Y, Silverman DT, Jones RR, Garcia C, Bell ML, Thurston GD. Long-term exposure to ozone and cause-specific mortality risk in the United States. American Journal of Respiratory and Critical Care Medicine 2019;200(8):1022-1031. |
R831697 (Final) R835871 (2019) R835871 (2020) R838300 (2020) |
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Journal Article | Manichaikul A, Wang XQ, Li L, Erdmann J, Lettre G, Bis JC, Waterworth D, Cushman M, Jenny NS, Post WS, Palmas W, Tsai MY, Wallentin L, White H, Schunkert H, O'Donnell CJ, Herrington DM, Rich SS, O'Donoghue ML, Rodriguez A. Lp-PLA2 , scavenger receptor class B type I gene (SCARB1 ) rs10846744 variant, and cardiovascular disease. PloS One 2018;13(10):e0204352. |
R838300 (2018) R838300 (2020) |
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Journal Article | Miller KA, Spalt EW, Gassett AJ, Curl CL, Larson TV, Avol E, Allen RW, Vedal S, Szpiro AA, Kaufman JD. Estimating ambient-origin PM2.5 exposure for epidemiology: observations, prediction, and validation using personal sampling in the Multi-Ethnic Study of Atherosclerosis. Journal of Exposure Science and Environmental Epidemiology 2019;29(2):227-237. |
R831697 (Final) R834796 (Final) R838300 (2018) R838300 (2020) |
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Journal Article | Ong K, McClelland R, Allison M, Cushman M, Garg P, Tsai M, Rye K, Tabet F. Lipoprotein (a) and coronary artery calcification:prospective study assessing interactions with other risk factors. METABOLISM 2021;116. |
R831697 (Final) R838300 (2021) |
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Journal Article | Pelkus A, Younan D, Wang X, Beavers D, Espeland M, Gatz M, Gruenwald T, Kaufman J, Chui H, Millstein J, Rapp S, Manson J, Resnick S, Wellenius G, Whitsel E, Widman K, Chen J. Associations Between Air Pollution Exposure and Empirically Derived Profiles of Cognitive Performance in Older Women. JOURNAL OF ALZHEIMER'S DISEASE 2021;84(4):1691-1707. |
R831697 (Final) R838300 (2021) |
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Journal Article | Pelkus A, Resnick S, Wang X, Beavers D, Espeland M, Gatz M, Gruenwald T, Millstein J, Chui H, Kaufman J, Manson J, Wellenius G, Whitsel E, Widman K, Younan D, Chen J. Ambient air pollution exposure and in Reasing depressive symptoms in older women:The mediating Role of the prefrontal cortex and insula. SCIENCE OF THE TOTAL ENVIRONMENT 2022;823(153642). |
R831697 (Final) R838300 (2021) |
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Journal Article | Petkus AJ, Younan D, Wang X, Beavers DP, Espeland MA, Gatz M, Gruenewald TL, Kaufman JD, Chui HC, Manson JE, Resnick SM. Air Pollution and the Dynamic Association Between Depressive Symptoms and Memory in Oldest‐Old Women. Journal of the American Geriatrics Society 2020 Nov 17. |
R838300 (2020) |
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Journal Article | Pewowaruk R, Korcarz C, Tedla Y, Mitchell C, Gepner A. CAROTID ARTERY STIFFNESS MECHANISMS IN HYPERTENSION AND THEIR ASSOCIATION WITH ECHOLUCENCY AND TEXTURE FEATURES:THE MULTI-ETHNIC STUDY OF ATHEROSCLEROSIS (MESA). ULTRASOUND IN MEDICINE AND BIOLOGY 2022;48(11):2249-2257. |
R831697 (Final) R838300 (2021) |
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Journal Article | Pewowaruk R, KOrcarz C, Stein J, Bluemke D, Tedla Y, Gepner A. Methods of arterial stiffness calculation and cardiovascular disease events: the multiethnic study of atherosclerosis. JOURNAL OF HYPERTENSION 2023;41(3):486-493 |
R831697 (Final) R838300 (2021) |
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Journal Article | Phishgar F, Shabani M, Silva T, Bluemke D, Budoff M, Barr R, Allison M, Bertoni A, Post W, Lima J, Demehri S. Adipose tissue biomarkers and type 2 diabetes incidence in normoglycemic participants in the MESA Arthritis Ancillary Study:A cohort study. PLOS MEDICINE 2021;18(7):e1003700. |
R831697 (Final) R838300 (2021) |
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Journal Article | Pishgar F, Shabani M, Silva T, Blumeke D, Budoff M, Barr R, Allison M, Post W, Lima J, Demehri S. Quantitative Analysis of Adipose Depots by Using Chest CT and Associations with All-Cause Mortality in Chronic Obstructive Pulmonary Disease:Longitudinal Analysis from MESArthritis Ancillary Study. RADIOLOGY 2021;299(3):703-711. |
R838300 (2021) |
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Journal Article | Razavi A, Allen N, Dzaye O, Michos E, Budoff M, Lima J, Liu K, Post W, Blumenthal R. Risk Factors for Incident Coronary Artery Calcium in Younger (Age 32 to 45 Years) Versus Intermediate (46 to 64 Years) Versus Older (65 to 84 Years) Persons. AMERICAN JOURNAL OF CARDIOLOGY 2022;184:14-21. |
R831697 (Final) R838300 (2021) |
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Journal Article | Sayanthan S, Allison M, Dudoff M, Kye K, Ong K. Relationship of fibroblast growth factor 21 with the prevalence and progression of vascular and valvular calcification: Multi-ethnic study of atherosclerosis. INTERNATIONAL JOURNAL OF CARDIOLOGY 2023;370:388-395 |
R831697 (Final) R838300 (2021) |
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Journal Article | Shea S, Stein JH, Jorgensen NW, McClelland RL, Tascau L, Shrager S, Heinecke JW, Yvan-Charvet L, Tall AR. Cholesterol mass efflux capacity, incident cardiovascular disease, and progression of carotid plaque:the Multi-Ethnic Study of Atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology 2019;39(1):89-96. |
R831697 (Final) R838300 (2019) R838300 (2020) |
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Journal Article | Sung YJ, Winkler TW, de Las Fuentes L, Bentley AR, Brown MR, Kraja AT, Schwander K, Ntalla I, Guo X, Franceschini N, Lu Y, Cheng CY, Sim X, Vojinovic D, Marten J, Musani SK, Li C, Feitosa MF, Kilpelainen TO, Richard MA, Noordam R, Aslibekyan S, Aschard H, Bartz TM, Dorajoo R, Liu Y, Manning AK, Rankinen T, Smith AV, et al. A large-scale multi-ancestry genome-wide study accounting for smoking behavior identifies multiple significant loci for blood pressure. The American Journal of Human Genetics 2018;102(3):375-400. |
R838300 (2018) R838300 (2020) |
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Journal Article | Wang X, Younan D, Petk A, Beavers D, Espeland M, Chiu H, Rsnick S, Gatz M, Kaufman J, Welleni G, Whitsel E, Manson J, Chen J. Ambient Air Pollution and Long-Term Trajectories of Episodic Memory Decline among Older Women in the WHIMS-ECHO Cohort. ENVIRONMENTAL HEALTH PERSPECTIVES 2020;129(9):97009. |
R838300 (2021) |
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Journal Article | Wang X, Younan D, Millstein J, Petkus A, Garcia E, Beavers D, Espland M, Chui H, Resnick S, Gatz M, Kaufman D, Wellenious G, Whitsel E, Manson J, Rapp S, Chen J. Association of improved air quality with lower dementiaRisk in older women. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES 2022;119(2):e2107833119. |
R838300 (2021) |
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Journal Article | Weze K, Obisean O, Dardari Z, Cainzos-Achirica M, Dzay O, Graham G, miedema M, Yeboah J, DeFilippis A, Nasir K, Blaha M, Osei A. The Interplay of Race/Ethnicity and Obesity on the Incidence of Venous Thromboembolism. AMERICAN JOURNAL OF PREVENTIVE MEDICINE 2022;63(1):E11-E20. |
R831697 (Final) R838300 (2021) |
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Journal Article | Younan D, Wang X, Millstein J, Petkus A, Beavers D, Espeland M, Chui H, Resnick S, Gatz M, Kauffman J, Wellenius G, Whitsel E, Manson J, Rapp S, Chen J. Air quality improvement and cognitive decline in community-dwelling older women in the United States:A longitudinal cohort study. PLOS MEDICINE 2022;19(2):e1003893. |
R831697 (Final) R838300 (2021) |
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Journal Article | Aaron CP, Schwartz JE, Hoffman EA, Angelini E, Austin JH, Cushman M, Jacobs Jr DR, Kaufman JD, Laine A, Smith LJ, Yang J. A longitudinal cohort study of aspirin use and progression of emphysema-like lung characteristics on CT imaging:the MESA Lung Study. Chest 2018;154(1):41-50. |
R838300 (2019) R838300 (2020) |
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Journal Article | Oelsner EC, Balte PP, Cassano PA, Couper D, Enright PL, Folsom AR, Hankinson J, Jacobs Jr DR, Kalhan R, Kaplan R, Kronmal R. Harmonization of respiratory data from 9 US population-based cohorts:the NHLBI pooled cohorts study. American Journal of Epidemiology 2018;187(11):2265-2278. |
R838300 (2019) R838300 (2020) |
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Journal Article | Aroner SA, Koch M, Mukamal KJ, Furtado JD, Stein JH, Tattersall MC, McClelland RL, Jensen MK. High‐density lipoprotein subspecies defined by Apolipoprotein C‐III and subclinical atherosclerosis measures:MESA (the multi‐ethnic study of atherosclerosis). Journal of the American Heart Association 2018;7(6):e007824. |
R838300 (2019) R838300 (2020) |
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Journal Article | Oelsner EC, Smith BM, Hoffman EA, Kalhan R, Donohue KM, Kaufman JD, Nguyen JN, Manichaikul AW, Rotter JI, Michos ED, Jacobs Jr DR. Prognostic significance of large airway dimensions on computed tomography in the general population. The multi-ethnic study of atherosclerosis (MESA) lung study. Annals of the American Thoracic Society 2018;15(6):718-727. |
R838300 (2019) R838300 (2020) |
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Journal Article | Wang M, Aaron CP, Madrigano J, Hoffman EA, Angelini E, Yang J, Laine A, Vetterli TM, Kinney PL, Sampson PD, Sheppard LE. Association between long-term exposure to ambient air pollution and change in quantitatively assessed emphysema and lung function. JAMA 2019;322(6):546-556. |
R831697 (Final) R834798 (Final) R838300 (2019) R838300 (2020) |
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Journal Article | Wang M, Sampson PD, Sheppard LE, Stein JH, Vedal S, Kaufman JD. Long-term exposure to ambient ozone and progression of subclinical arterial disease:the multi-ethnic study of atherosclerosis and air pollution. Environmental Health Perspectives 2019;127(5):057001. |
R834796 (Final) R838300 (2019) R838300 (2020) |
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Journal Article | Oelsner EC, Ortega VE, Smith BM, Nguyen JN, Manichaikul AW, Hoffman EA, Guo X, Taylor KD, Woodruff PG, Couper DJ, Hansel NN. A genetic risk score associated with chronic obstructive pulmonary disease susceptibility and lung structure on computed tomography. American Journal of Respiratory and Critical Care Medicine 2019;200(6):721-731. |
R838300 (2019) R838300 (2020) |
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Journal Article | Aaron CP, Hoffman EA, Kawut SM, Austin JH, Budoff M, Michos ED, Stukovsky KH, Sack C, Szpiro AA, Watson KD, Kaufman JD. Ambient air pollution and pulmonary vascular volume on computed tomography:the MESA Air Pollution and Lung cohort studies. European Respiratory Journal 2019;53(6):1802116. |
R838300 (2019) R838300 (2020) |
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Journal Article | Quraishi SM, Lin PC, Richter KS, Hinckley MD, Yee B, Neal-Perry G, Sheppard L, Kaufman JD, Hajat A. Ambient air pollution exposure and fecundability in women undergoing in vitro fertilization. Environmental Epidemiology 2019;3(1):e036. |
R838300 (2019) R838300 (2020) |
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Journal Article | Mitchell CC, Korcarz CE, Gepner AD, Nye R, Young RL, Matsuzaki M, Post WS, Kaufman JD, McClelland RL, Stein JH. Carotid artery echolucency, texture features, and incident cardiovascular disease events:The MESA Study. Journal of the American Heart Association 2019;8(3):e010875. |
R838300 (2019) R838300 (2020) |
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Journal Article | Hajat A, Diez Roux AV, Castro-Diehl C, Cosselman K, Golden SH, Hazlehurst MF, Szpiro A, Vedal S, Kaufman JD. The association between long-term air pollution and urinary catecholamines:evidence from the multi-ethnic study of atherosclerosis. Environmental Health Perspectives 2019;127(5):057007. |
R838300 (2019) R838300 (2020) |
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Journal Article | Billings ME, Gold D, Szpiro A, Aaron CP, Jorgensen N, Gassett A, Leary PJ, Kaufman JD, Redline SR. The association of ambient air pollution with sleep apnea:the multi-ethnic study of atherosclerosis. Annals of the American Thoracic Society 2019;16(3):363-370. |
R838300 (2019) R838300 (2020) |
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Journal Article | Zusman M, Schumacher CS, Gassett AJ, Spalt EW, Austin E, Larson TV, Carvlin G, Seto E, Kaufman JD, Sheppard L. Calibration of low-cost particulate matter sensors:model development for a multi-city epidemiological study. Environment International 2020;134:105329.. |
R831697 (Final) R838300 (2019) R838300 (2020) |
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Journal Article | Karger AB, Steffen BT, Nomura SO, Guan W, Garg PK, Szklo M, Budoff MJ, Tsai MY. Association between homocysteine and vascular calcification incidence, prevalence, and progression in the MESA cohort. Journal of the American Heart Association 2020;9(3):e013934. |
R838300 (2020) |
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Journal Article | Smith BM, Kirby M, Hoffman EA, Kronmal RA, Aaron SD, Allen NB, Bertoni A, Coxson HO, Cooper C, Couper DJ, Criner G. Association of Dysanapsis With Chronic Obstructive Pulmonary Disease Among Older Adults. Jama 2020;323(22):2268-80. |
R838300 (2020) |
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Journal Article | Loftus CT, Ni Y, Szpiro AA, Hazlehurst MF, Tylavsky FA, Bush NR, Sathyanarayana S, Carroll KN, Young M, Karr CJ, LeWinn KZ. Exposure to ambient air pollution and early childhood behavior:A longitudinal cohort study. Environmental Research 2020;183:109075. |
R838300 (2020) |
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Journal Article | Dzaye O, Dardari ZA, Cainzos-Achirica M, Blankstein R, Szklo M, Budoff MJ, Lima JA, Blumenthal RS, Nasir K, Blaha MJ. Incidence of new coronary calcification:time to conversion from CAC= 0. Journal of the American College of Cardiology 2020;75(13):1610-3. |
R838300 (2020) |
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Journal Article | Kulick ER, Wellenius GA, Boehme AK, Joyce NR, Schupf N, Kaufman JD, Mayeux R, Sacco RL, Manly JJ, Elkind MS. Long-term exposure to air pollution and trajectories of cognitive decline among older adults. Neurology 2020;94(17):e1782-92. |
R838300 (2020) |
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Journal Article | Kulick ER, Elkind MS, Boehme AK, Joyce NR, Schupf N, Kaufman JD, Mayeux R, Manly JJ, Wellenius GA. Long-term exposure to ambient air pollution, APOE-ε4 status, and cognitive decline in a cohort of older adults in northern Manhattan. Environment International 2020;136:105440. |
R838300 (2020) |
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Journal Article | Razavi AC, Wong N, Budoff M, Bazzano LA, Kelly TN, He J, Fernandez C, Lima J, Polak JF, Mongraw-Chaffin M, deFilippi C. Predicting Long-Term Absence of Coronary Artery Calcium in Metabolic Syndrome and Diabetes:The MESA Study. JACC:Cardiovascular Imaging 2020 Oct 28. |
R831697 (Final) R838300 (2020) |
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Journal Article | Ni Y, Szpiro AA, Young MT, Loftus CT, Bush NR, LeWinn KZ, Sathyanarayana S, Enquobahrie DA, Davis RL, Kratz M, Fitzpatrick AL. Associations of pre-and postnatal air pollution exposures with child blood pressure and modification by maternal nutrition:a prospective study in the CANDLE cohort. Environmental health perspectives 2021;129(4):047004. |
R831697 (Final) R838300 (2021) |
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Journal Article | Oelsner EC, Balte PP, Grams ME, Cassano PA, Jacobs DR, Barr RG, Burkart KM, Kalhan R, Kronmal R, Loehr LR, O’Connor GT. Albuminuria, lung function decline, and risk of incident chronic obstructive pulmonary disease. The NHLBI Pooled Cohorts Study. American Journal of Respiratory and Critical Care Medicine. 2019;199(3):321-332. |
R838300 (2019) R838300 (2020) |
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Journal Article | Costa MD, Redline S, Soliman EZ, Goldberger AL, Heckbert SR. Fragmented Sinoatrial Dynamics in the Prediction of Atrial Fibrillation:The Multi-Ethnic Study of Atherosclerosis. American Journal of Physiology-Heart and Circulatory Physiology 2020 Sep 28. |
R838300 (2020) |
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Journal Article | Kwon Y, Mariani S, Reid M, Jacobs Jr D, Lima J, Kapur V, Punjabi N, Redline S. Lung to Finger Circulation Time in Sleep Study and Coronary Artery Calcification:The Multi-Ethnic Study of Atherosclerosis [Brief Communication]. Sleep Medicine 2020 Jun 3. |
R838300 (2020) |
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Journal Article | Zusman M, Gassett AJ, Kirwa K, Barr RG, Cooper CB, Han MK, Kanner RE, Koehler K, Ortega VE, Paine R, Paulin L. Modeling Residential Indoor Concentrations of PM2. 5, NO2, NOx, and secondhand smoke in the Subpopulations and Intermediate Outcome Measures in COPD (SPIROMICS) Air Study. Indoor air 2020 Oct 9. |
R838300 (2020) |
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Journal Article | Inoue K, Goldwater D, Allison M, Seeman T, Kestenbaum BR, Watson KE. Serum Aldosterone Concentration, Blood Pressure, and Coronary Artery Calcium:The Multi-Ethnic Study of Atherosclerosis. Hypertension 2020 May 18:HYPERTENSIONAHA-120. |
R838300 (2020) |
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Journal Article | Hajat A, Hazlehurst MF, Golden SH, Merkin SS, Seeman T, Szpiro AA, Kaufman JD, Roux AD. The cross-sectional and longitudinal association between air pollution and salivary cortisol:Evidence from the Multi-Ethnic Study of Atherosclerosis. Environment international 2019 Oct 1;131:105062. |
R838300 (2020) |
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Journal Article | Dzaye O, Dardari ZA, Cainzos-Achirica M, Blankstein R, Agatston AS, Duebgen M, Yeboah J, Szklo M, Budoff MJ, Lima JA, Blumenthal RS. Warranty Period of a Calcium Score of Zero:Comprehensive Analysis From the Multiethnic Study of Atherosclerosis. JACC:Cardiovascular Imaging 2020 Oct 28. |
R838300 (2020) |
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.