Grantee Research Project Results
Publications Details for Grant Number R828044
Bioavailability of Haloacetates in Human Subjects
Other Views
- All
Publications - Selected
Publication Types - Journal
Articles - Publications Submitted
After Final Report - Redisplay this page with
Reference Title, Journal, and Author Columns - Display this Page
in RIS Format
| Reference Type | Citation | Progress Report Year | Document Sources |
|---|---|---|---|
| Abstract | Schultz IR, Shangraw RE, Stenner RD, Keys DA, et al. Haloacetic acid pharmacokinetics in rhesus monkeys and humans: classical and PBPK modeling approaches. Toxicological Sciences 2004;78(S1):703 (abstract). |
R828044 (Final) |
not available |
| Abstract | Schultz I, Saghir S, Shangraw R. Oral bioavailability of dichloroacetate in human subjects. Toxicological Sciences 2003;72(S1):702 (abstract). |
R828044 (Final) |
not available |
| Journal Article | Keys DA, Schultz IR, Mahle DA, Fisher JW. A quantitative description of suicide inhibition of dichloroacetic acid in rats and mice. Toxicological Sciences 2004;82(2):381-393. |
R828044 (Final) |
|
| Journal Article | Saghir SA, Schultz IR. Toxicokinetics and oral bioavailability of halogenated acetic acids from two mixtures in naive and GSTzeta-depleted rats. Toxicological Sciences 2005;84(2):214-224. |
R825954 (Final) R828044 (Final) |
|
| Journal Article | Schultz IR, Shangraw RE. Effect of short-term drinking water exposure to dichloroacetate on its pharmacokinetics and oral bioavailability in human volunteers: a stable isotope study. Toxicological Sciences 2006;92(1):42-50. |
R825954 (Final) R828044 (Final) |
|
| Presentation | Saghir SA, Schultz IR. Microsomal metabolism of trihalogentated acetic acids. Presented at the 9th International Congress of Toxicology, Brisbane, Australia, July 2001. |
R825954 (Final) R828044 (Final) |
not available |
| Presentation | Saghir SA, Schultz IR. Low dose toxicokinetics and oral bioavailability of dichloroacetate in naïve and GST-ZETA depleted rats. Presented at the 40th Annual Meeting of the Society of Toxicology, San Francisco, CA, March 2001. |
R825954 (Final) R828044 (Final) |
not available |
| Presentation | Saghir SA, Schultz IR. Microsomal metabolism of trihalogentated acetic acids. Presented at the 40th Annual Meeting of the Society of Toxicology, San Francisco, CA, March 2001. |
R825954 (Final) R828044 (Final) |
not available |
| Presentation | Saghir SA, Schultz IR. Disposition and oral bioavailability of haloacetate mixtures in F344 rats. Presented at the 41st Annual Meeting of the Society of Toxicology, Nashville, TN, March 2002. |
R825954 (Final) R828044 (Final) |
not available |
| Presentation | Schultz IR, Saghir S. Bioavailability of chlorinated and brominated haloacetate mixtures. Presented at the Symposium on Chemical Mixtures, sponsored by Colorado State University, Ft. Collins, CO, January 2001. |
R825954 (Final) R828044 (Final) |
not available |
| Presentation | Schultz IR, Sylvester SR. Stereospecific disposition of bromochloro- and fluorochloroacetate: effect of GST-zeta depletion. Presented at the 41st Annual Meeting of the Society of Toxicology, Nashville, TN, March 2002. |
R825954 (Final) R828044 (Final) |
not available |
| Presentation | Stenner RD, Schultz IR. Physiologically based pharmacokinetic modeling of dichloroacetic acid. Presented at the 41st Annual Meeting of the Society of Toxicology, Nashville, TN, March 2002. |
R825954 (Final) R828044 (Final) |
not available |
| Presentation | Sylvester SR, Kato-Weinstein J, Schultz IR. Enantioselective metabolism and inhibition of bromochloroacetic acid by glutahione transferase-zeta. Presented at the 41st Annual Meeting of the Society of Toxicology, Nashville, TN, March 2002. |
R825954 (Final) R828044 (Final) |
not available |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.