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Grantee Research Project Results

Publications Details for Grant Number CR835785

Initial Annual CEMALB Progress Report: Human Health Effects of Environmental Pollutants

RFA: Human Health Effects of Environmental Pollutants (2014)

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Abstract (1)
Conference Proceedings (1)
Journal Article (50)
Presentation (31)
Reference Type Reference Title Journal Author Citation Progress Report Year Document Sources
Abstract Impact of GSTM1 Genotype on Airway Response to Inhaled Wood Smoke Particles Abstract 90 None Burbank AJ, Hernandez ML, Mills KH, Alexis NE, Peden DB Burbank AJ, Hernandez ML, Mills KH, Alexis NE, Peden DB. Impact of GSTM1 Genotype on Airway Response to Inhaled Wood Smoke Particles Abstract 90. Presented at the Annual Meeting of the American Academy of Allergy, Asthma and Immunology2018;141(2):AB29 CR835785 (2017)
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Conference Proceedings Wood Smoke Particle Exposure Increases Viral Susceptibility In Respiratory Epithelial Cells. None Baker E, Brighton LE, Jaspers I Baker E, Brighton LE, Jaspers I. Wood Smoke Particle Exposure Increases Viral Susceptibility In Respiratory Epithelial Cells. Presented at ATC Conferences InA32. MICROBIAL INTERACTIONS AND HOST DEFENSE 2015;(pp. A1313-A1313). American Thoracic Society. CR835785 (2015)
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Journal Article Linking the epigenome with exposure effects and susceptibility:The epigenetic seed and soil model. TOXICOLOGICAL SCIENCES Bowers EC, McCullough SD Bowers EC, McCullough SD. Linking the epigenome with exposure effects and susceptibility:The epigenetic seed and soil model. Toxicological Sciences 2016;155(2):302-14 CR835785 (2016)
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Journal Article Expanded characterization of in vitro polarized M0, M1, and M2 human monocyte-derived macrophages: Bioenergetic and secreted mediator profiles PLOS ONE Hickman E, Smyth T, Cabos-Uribe C, Immormino R, Rebuli M, Moran T, Alexis N, Jaspers I Hickman E, Smyth T, Cabos-Uribe C, Immormino R, Rebuli M, Moran T, Alexis N, Jaspers I. Expanded characterization of in vitro polarized M0, M1, and M2 human monocyte-derived macrophages: Bioenergetic and secreted mediator profiles. PLOS ONE 2023;18(3):e0279037 CR835785 (Final)
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Journal Article Reproducibility of the inflammatory response to inhaled endotoxin in healthy volunteers. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Kobernick AK, Peden DB, Zhou H, Zhou Q, Dillon MA, Alexis NE Kobernick AK, Peden DB, Zhou H, Zhou Q, Dillon MA, Alexis NE. Reproducibility of the inflammatory response to inhaled endotoxin in healthy volunteers. Journal of Allergy and Clinical Immunology. 2016;138(4):1205-7 CR835785 (2015)
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Journal Article High-throughput video processing of heart rate responses in multiple wild-type embryonic Zebrafish per imaging field. SCIENTIFIC REPORTS Martin WK, Tennant AH, Conolly RB, Prince K, Stevens JS, DeMarini DM, Martin BL, Thompson LC, Gilmour MI, Cascio WE, Hays MD Martin WK, Tennant AH, Conolly RB, Prince K, Stevens JS, DeMarini DM, Martin BL, Thompson LC, Gilmour MI, Cascio WE, Hays MD. High-throughput video processing of heart rate responses in multiple wild-type embryonic Zebrafish per imaging field. Scientific reports 2019;9(1):1-4. CR835785 (2019)
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Journal Article Baseline chromatin modification levels may predict interindividual variability in ozone-induced gene expression. TOXICOLOGICAL SCIENCES. McCullough SD, Bowers EC, On DM, Morgan DS, Dailey LA, Hines RN, Devlin RB, Diaz-Sanchez D McCullough SD, Bowers EC, On DM, Morgan DS, Dailey LA, Hines RN, Devlin RB, Diaz-Sanchez D. Baseline chromatin modification levels may predict interindividual variability in ozone-induced gene expression. Toxicological Sciences. 2015;150(1):216-24 CR835785 (2015)
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Journal Article Using Chromatin Immunoprecipitation in Toxicology:A Step‐by‐Step Guide to Increasing Efficiency, Reducing Variability, and Expanding Applications. CURRENT PROTOCOLS IN TOXICOLOGY McCullough SD, On DM, Bowers EC McCullough SD, On DM, Bowers EC. Using Chromatin Immunoprecipitation in Toxicology:A Step‐by‐Step Guide to Increasing Efficiency, Reducing Variability, and Expanding Applications. Current protocols in toxicology 2017;72(1):3-14 CR835785 (2016)
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Journal Article Systemic metabolic derangement, pulmonary effects, and insulin insufficiency following subchronic ozone exposure in rats. TOXICOLOGY AND APPLIED PHARMACOLOGY Miller DB, Snow SJ, Henriquez A, Schladweiler MC, Ledbetter AD, Richards JE, Andrews DL, Kodavanti UP Miller DB, Snow SJ, Henriquez A, Schladweiler MC, Ledbetter AD, Richards JE, Andrews DL, Kodavanti UP. Systemic metabolic derangement, pulmonary effects, and insulin insufficiency following subchronic ozone exposure in rats. Toxicology and applied pharmacology 2016;306:47-57 CR835785 (2016)
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Journal Article Repeated measures of inflammation, blood pressure, and heart rate variability associated with traffic exposures in healthy adults. ENVIRONMENTAL HEALTH. Mirowsky JE, Peltier RE, Lippmann M, Thurston G, Chen LC, Neas L, Diaz-Sanchez D, Laumbach R, Carter JD, Gordon T Mirowsky JE, Peltier RE, Lippmann M, Thurston G, Chen LC, Neas L, Diaz-Sanchez D, Laumbach R, Carter JD, Gordon T. Repeated measures of inflammation, blood pressure, and heart rate variability associated with traffic exposures in healthy adults. Environmental Health. 2015;14(1):66 CR835785 (2015)
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Journal Article A novel approach for measuring residential socioeconomic factors associated with cardiovascular and metabolic health. JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY Mirowsky JE, Devlin RB, Diaz-Sanchez D, Cascio W, Grabich SC, Haynes C, Blach C, Hauser ER, Shah S, Kraus W, Olden K Mirowsky JE, Devlin RB, Diaz-Sanchez D, Cascio W, Grabich SC, Haynes C, Blach C, Hauser ER, Shah S, Kraus W, Olden K. A novel approach for measuring residential socioeconomic factors associated with cardiovascular and metabolic health. Journal of Exposure Science and Environmental Epidemiology 2017;27(3):281 CR835785 (2016)
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Journal Article Plasma sterols and vitamin D are correlates and predictors of ozone-induced inflammation in the lung: A pilot study PLOS ONE Perryman A, Kim H, Payton A, Rager J, McNell E, Rebuli M, Wells H, Almond M, Antinori J, Alexis N, Porter N, Jasters I Perryman A, Kim H, Payton A, Rager J, McNell E, Rebuli M, Wells H, Almond M, Antinori J, Alexis N, Porter N, Jasters I. Plasma sterols and vitamin D are correlates and predictors of ozone-induced inflammation in the lung: A pilot study. PLOS ONE 2023;18(5):e285721 CR835785 (Final)
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Journal Article Alterations in airway microbiota in patients with PaO2/FiO2 ratio≤ 300 after burn and inhalation injury. PLOS ONE Walsh DM, McCullough SD, Yourstone S, Jones SW, Cairns BA, Jones CD, Jaspers I, Diaz-Sanchez D Walsh DM, McCullough SD, Yourstone S, Jones SW, Cairns BA, Jones CD, Jaspers I, Diaz-Sanchez D. Alterations in airway microbiota in patients with PaO2/FiO2 ratio≤ 300 after burn and inhalation injury. PloS one 2017;12(3):e0173848 CR835785 (2016)
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Journal Article Comparison of multiplexed protein analysis platforms for the detection of biomarkers in the nasal epithelial lining fluid of healthy subjects JOURNAL OF IMMUNOLOGICAL METHODS Zetlen H, Cao K, Schichlein K, Knight N, Maecker H, Nadeau K, Rebuli M, Rise M Zetlen H, Cao K, Schichlein K, Knight N, Maecker H, Nadeau K, Rebuli M, Rise M. Comparison of multiplexed protein analysis platforms for the detection of biomarkers in the nasal epithelial lining fluid of healthy subjects. JOURNAL OF IMMUNOLOGICAL METHODS 2023;517(113473). CR835785 (Final)
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Journal Article Outdoor Air Pollution and New-Onset Airway Disease. None Thurston GD, Balmes JR, Garcia E, Gilliland FD, Rice MB, Schikowski T, Van Winkle LS, Annesi-Maesano I, Burchard EG, Carlsten C, Harkema JR Thurston GD, Balmes JR, Garcia E, Gilliland FD, Rice MB, Schikowski T, Van Winkle LS, Annesi-Maesano I, Burchard EG, Carlsten C, Harkema JR. Outdoor Air Pollution and New-Onset Airway Disease. An Official American Thoracic Society Workshop Report. Annals of the American Thoracic Society 2020;17(4):387-98. CR835785 (2019)
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Journal Article Oleic acid induces acute pulmonary injury and inflammation in vivo JOURNAL OF INFLAMMATION Bass V Bass V. San Antonio Oleic acid induces acute pulmonary injury and inflammation in vivo. Society of Toxicology, 2017;10(1):34 CR835785 (2017)
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Journal Article Inhaled ozone (O3)-induces changes in serum metabolomic and liver transcriptomic profiles in rats. TOXICOLOGY AND APPLIED PHARMACOLOGY Miller DB, Karoly ED, Jones JC, Ward WO, Vallanat BD, Andrews DL, Schladweiler MC, Snow SJ, Bass VL, Richards JE, Ghio AJ Miller DB, Karoly ED, Jones JC, Ward WO, Vallanat BD, Andrews DL, Schladweiler MC, Snow SJ, Bass VL, Richards JE, Ghio AJ. Inhaled ozone (O3)-induces changes in serum metabolomic and liver transcriptomic profiles in rats. Toxicology and applied pharmacology 2015;286(2):65-79. CR835785 (2017)
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Journal Article Diesel exposure suppresses natural killer cell function and resolution of eosinophil inflammation:a randomized controlled trial of exposure in allergic rhinitics. PARTICLE AND FIBRE TOXICOLOGY. Pawlak EA, Noah TL, Zhou H, Chehrazi C, Robinette C, Diaz-Sanchez D, Müller L, Jaspers I Pawlak EA, Noah TL, Zhou H, Chehrazi C, Robinette C, Diaz-Sanchez D, Müller L, Jaspers I. Diesel exposure suppresses natural killer cell function and resolution of eosinophil inflammation:a randomized controlled trial of exposure in allergic rhinitics. Particle and fibre toxicology. 2015;13(1):24 CR835785 (2015)
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Journal Article Ambient air pollution and increases in blood pressure:role for biological constituents of particulate matter. HYPERTENSION. Cascio WE, Gilmour MI, Peden DB Cascio WE, Gilmour MI, Peden DB. Ambient air pollution and increases in blood pressure:role for biological constituents of particulate matter. Hypertension. 2015;66(3):469-71. CR835785 (2015)
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Journal Article Noninvasive effects measurements for air pollution human studies:methods, analysis, and implications. ENVIRONMENTAL EPIDEMIOLOGY. Mirowsky J, Gordon T Mirowsky J, Gordon T. Noninvasive effects measurements for air pollution human studies:methods, analysis, and implications. Journal of Exposure Science and Environmental Epidemiology. 2015;25(4):354 CR835785 (2015)
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Journal Article Novel applications for a noninvasive sampling method of the nasal mucosa. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY Rebuli ME, Speen AM, Clapp PW, Jaspers I Rebuli ME, Speen AM, Clapp PW, Jaspers I. Novel applications for a noninvasive sampling method of the nasal mucosa. American Journal of Physiology-Lung Cellular and Molecular Physiology 2016;312(2):L288-96 CR835785 (2016)
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Journal Article A proof-of-concept clinical study examining the NRF2 activator sulforaphane against neutrophilic airway inflammation. RESPIRATORY RESEARCH Duran CG, Burbank AJ, Mills KH, Duckworth HR, Aleman MM, Kesic MJ, Peden DB, Pan Y, Zhou H, Hernandez ML Duran CG, Burbank AJ, Mills KH, Duckworth HR, Aleman MM, Kesic MJ, Peden DB, Pan Y, Zhou H, Hernandez ML. A proof-of-concept clinical study examining the NRF2 activator sulforaphane against neutrophilic airway inflammation. Respiratory Research 2016;17(1):89. CR835785 (2016)
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Journal Article Differential expression of pro-inflammatory and oxidative stress mediators induced by nitrogen dioxide and ozone in primary human bronchial epithelial cells. INHALATION TOXICOLOGY. Mirowsky JE, Dailey LA, Devlin RB Mirowsky JE, Dailey LA, Devlin RB. Differential expression of pro-inflammatory and oxidative stress mediators induced by nitrogen dioxide and ozone in primary human bronchial epithelial cells. Inhalation toxicology. 2016;28(8):374-82 CR835785 (2015)
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Journal Article Age-related differences in pulmonary effects of acute and subchronic episodic ozone exposures in Brown Norway rats. INHALATION TOXICOLOGY Snow SJ, Gordon CJ, Bass VL, Schladweiler MC, Ledbetter AD, Jarema KA, Phillips PM, Johnstone AF, Kodavanti UP Snow SJ, Gordon CJ, Bass VL, Schladweiler MC, Ledbetter AD, Jarema KA, Phillips PM, Johnstone AF, Kodavanti UP. Age-related differences in pulmonary effects of acute and subchronic episodic ozone exposures in Brown Norway rats. Inhalation toxicology 2016;28(7):313-23. CR835785 (2017)
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Journal Article Low-power wearable systems for continuous monitoring of environment and health for chronic respiratory disease. IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS. Dieffenderfer J, Goodell H, Mills S, McKnight M, Yao S, Lin F, Beppler E, Bent B, Lee B, Misra V, Zhu Y Dieffenderfer J, Goodell H, Mills S, McKnight M, Yao S, Lin F, Beppler E, Bent B, Lee B, Misra V, Zhu Y. Low-power wearable systems for continuous monitoring of environment and health for chronic respiratory disease. IEEE journal of biomedical and health informatics. 2016;20(5):1251-64. CR835785 (2015)
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Journal Article Adrenal-derived stress hormones modulate ozone-induced lung injury and inflammation. TOXICOLOGY AND APPLIED PHARMACOLOGY Henriquez A, House J, Miller DB, Snow SJ, Fisher A, Ren H, Schladweiler MC, Ledbetter AD, Wright F, Kodavanti UP Henriquez A, House J, Miller DB, Snow SJ, Fisher A, Ren H, Schladweiler MC, Ledbetter AD, Wright F, Kodavanti UP. Adrenal-derived stress hormones modulate ozone-induced lung injury and inflammation. Toxicology and applied pharmacology 2017;329:249-58 CR835785 (2016)
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Journal Article Respiratory effects and systemic stress response following acute acrolein inhalation in rats. TOXICOLOGICAL SCIENCES Snow SJ, McGee MA, Henriquez A, Richards JE, Schladweiler MC, Ledbetter AD, Kodavanti UP Snow SJ, McGee MA, Henriquez A, Richards JE, Schladweiler MC, Ledbetter AD, Kodavanti UP. Respiratory effects and systemic stress response following acute acrolein inhalation in rats. Toxicological Sciences 2017;158(2):454-64 CR835785 (2016)
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Journal Article Uterine artery flow and offspring growth in long-evans rats following maternal exposure to ozone during implantation. ENVIRONMENTAL HEALTH PERSPECTIVES Miller CN, Dye JA, Ledbetter AD, Schladweiler MC, Richards JH, Snow SJ, Wood CE, Henriquez AR, Thompson LC, Farraj AK, Hazari MS Miller CN, Dye JA, Ledbetter AD, Schladweiler MC, Richards JH, Snow SJ, Wood CE, Henriquez AR, Thompson LC, Farraj AK, Hazari MS. Uterine artery flow and offspring growth in long-evans rats following maternal exposure to ozone during implantation. Environmental health perspectives 2017;125(12):127005 CR835785 (2017)
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Journal Article Ozone exposure is associated with acute changes in inflammation, fibrinolysis, and endothelial cell function in coronary artery disease patients. ENVIRONMENTAL HEALTH Mirowsky JE, Carraway MS, Dhingra R, Tong H, Neas L, Diaz-Sanchez D, Cascio W, Case M, Crooks J, Hauser ER, Dowdy ZE Mirowsky JE, Carraway MS, Dhingra R, Tong H, Neas L, Diaz-Sanchez D, Cascio W, Case M, Crooks J, Hauser ER, Dowdy ZE. Ozone exposure is associated with acute changes in inflammation, fibrinolysis, and endothelial cell function in coronary artery disease patients. Environmental Health 2017;16(1):126 CR835785 (2016)
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Journal Article Secondhand hookah smoke:an occupational hazard for hookah bar employees. TOBACCO CONTROL. Zhou S, Behrooz L, Weitzman M, Pan G, Vilcassim R, Mirowsky JE, Breysee P, Rule A, Gordon T Zhou S, Behrooz L, Weitzman M, Pan G, Vilcassim R, Mirowsky JE, Breysee P, Rule A, Gordon T. Secondhand hookah smoke:an occupational hazard for hookah bar employees. Tobacco control. 2017;26(1):40-5 CR835785 (2015)
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Journal Article Assessing the impact of air pollution on childhood asthma morbidity:how, when, and what to do. CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY Burbank AJ, Peden DB Burbank AJ, Peden DB. Assessing the impact of air pollution on childhood asthma morbidity:how, when, and what to do. Current opinion in allergy and clinical immunology2018;18(2):124-31 CR835785 (2018)
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Journal Article Adrenergic and glucocorticoid receptor antagonists reduce ozone-induced lung injury and inflammation. TOXICOLOGY AND APPLIED PHARMACOLOGY Henriquez AR, Snow SJ, Schladweiler MC, Miller CN, Dye JA, Ledbetter AD, Richards JE, Mauge-Lewis K, McGee MA, Kodavanti UP Henriquez AR, Snow SJ, Schladweiler MC, Miller CN, Dye JA, Ledbetter AD, Richards JE, Mauge-Lewis K, McGee MA, Kodavanti UP. Adrenergic and glucocorticoid receptor antagonists reduce ozone-induced lung injury and inflammation. Toxicology and applied pharmacology 2018;339:161-71 CR835785 (2017)
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Journal Article Neuroendocrine regulation of air pollution health effects:emerging insights. TOXICOLOGICAL SCIENCES Snow SJ, Henriquez AR, Costa DL, Kodavanti UP Snow SJ, Henriquez AR, Costa DL, Kodavanti UP. Neuroendocrine regulation of air pollution health effects:emerging insights. Toxicological Sciences 2018;164(1):9-20 CR835785 (2017)
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Journal Article Prenatal arsenic exposure and dietary folate and methylcobalamin supplementation alter the metabolic phenotype of C57BL/6J mice in a sex-specific manner. ARCHIVES OF TOXICOLOGY Huang MC, Douillet C, Dover EN, Stýblo M Huang MC, Douillet C, Dover EN, Stýblo M. Prenatal arsenic exposure and dietary folate and methylcobalamin supplementation alter the metabolic phenotype of C57BL/6J mice in a sex-specific manner. Archives of toxicology 2018;92(6):1925-37 CR835785 (2017)
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Journal Article Comparative cardiopulmonary effects of particulate matter-and ozone-enhanced smog atmospheres in mice. ENVIRONMENTAL SCIENCE & TECHNOLOGY Hazari MS, Stratford KM, Krantz QT, King C, Krug J, Farraj AK, Gilmour MI Hazari MS, Stratford KM, Krantz QT, King C, Krug J, Farraj AK, Gilmour MI. Comparative cardiopulmonary effects of particulate matter-and ozone-enhanced smog atmospheres in mice. Environmental science & technology 2018;52(5):3071-80. CR835785 (2017)
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Journal Article Early-life persistent vitamin D deficiency alters cardiopulmonary responses to particulate matter-enhanced atmospheric smog in adult mice. ENVIRONMENTAL SCIENCE & TECHNOLOGY Stratford K, Haykal-Coates N, Thompson L, Krantz QT, King C, Krug J, Gilmour MI, Farraj A, Hazari M Stratford K, Haykal-Coates N, Thompson L, Krantz QT, King C, Krug J, Gilmour MI, Farraj A, Hazari M. Early-life persistent vitamin D deficiency alters cardiopulmonary responses to particulate matter-enhanced atmospheric smog in adult mice. Environmental science & technology 2018;52(5):3054-61. CR835785 (2017)
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Journal Article Ozone-induced vascular contractility and pulmonary injury are differentially impacted by diets enriched with coconut oil, fish oil, and olive oil. TOXICOLOGICAL SCIENCES Snow SJ, Cheng WY, Henriquez A, Hodge M, Bass V, Nelson GM, Carswell G, Richards JE, Schladweiler MC, Ledbetter AD, Chorley B Snow SJ, Cheng WY, Henriquez A, Hodge M, Bass V, Nelson GM, Carswell G, Richards JE, Schladweiler MC, Ledbetter AD, Chorley B. Ozone-induced vascular contractility and pulmonary injury are differentially impacted by diets enriched with coconut oil, fish oil, and olive oil. Toxicological Sciences 2018;163(1):57-69 CR835785 (2017)
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Journal Article Beta-2 adrenergic and glucocorticoid receptor agonists modulate ozone-induced pulmonary protein leakage and inflammation in healthy and adrenalectomized rats. TOXICOLOGICAL SCIENCES Henriquez AR, Snow SJ, Schladweiler MC, Miller CN, Dye JA, Ledbetter AD, Richards JE, Hargrove MM, Williams WC, Kodavanti UP Henriquez AR, Snow SJ, Schladweiler MC, Miller CN, Dye JA, Ledbetter AD, Richards JE, Hargrove MM, Williams WC, Kodavanti UP. Beta-2 adrenergic and glucocorticoid receptor agonists modulate ozone-induced pulmonary protein leakage and inflammation in healthy and adrenalectomized rats. Toxicological Sciences 2018;166(2):288-305. CR835785 (2019)
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Journal Article Environmental risk factors for Toxoplasma gondii infections and the impact of latent infections on allostatic load in residents of Central North Carolina. BMC INFECTIOUS DISEASES Egorov AI, Converse R, Griffin SM, Styles J, Klein E, Sams E, Hudgens E, Wade TJ Egorov AI, Converse R, Griffin SM, Styles J, Klein E, Sams E, Hudgens E, Wade TJ. Environmental risk factors for Toxoplasma gondii infections and the impact of latent infections on allostatic load in residents of Central North Carolina. BMC infectious diseases 2018;18(1):421. CR835785 (2019)
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Journal Article Health and the Environment in North Carolina. NORTH CAROLINA MEDICAL JOURNAL Lyerly HK, Peden DB Lyerly HK, Peden DB. Health and the Environment in North Carolina. North Carolina medical journal2018;79(5):302-5 CR835785 (2018)
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Journal Article The Unexpected Health Effects of Air Pollution. NORTH CAROLINA MEDICAL JOURNAL Peden DB Peden DB. The Unexpected Health Effects of Air Pollution. North Carolina medical journal2018;79(5):309-11 CR835785 (2018)
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Journal Article A community‐engaged approach to investigate cardiovascular‐associated inflammation among American Indian women:A research protocol. RESEARCH IN NURSING & HEALTH Brooks JL, Berry DC, Currin EG, Ledford A, Knafl GJ, Fredrickson BL, Beeber LS, HAPPI Community Partnership Committee, Peden DB, Corbie‐Smith GM Brooks JL, Berry DC, Currin EG, Ledford A, Knafl GJ, Fredrickson BL, Beeber LS, HAPPI Community Partnership Committee, Peden DB, Corbie‐Smith GM. A community‐engaged approach to investigate cardiovascular‐associated inflammation among American Indian women:A research protocol. Research in nursing & health201942(3):165-75 CR835785 (2018)
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Journal Article A novel approach for exposing and sharing clinical data:the Translator Integrated Clinical and Environmental Exposures Service. None Fecho K, Pfaff E, Xu H, Champion J, Cox S, Stillwell L, Peden DB, Bizon C, Krishnamurthy A, Tropsha A, Ahalt SC Fecho K, Pfaff E, Xu H, Champion J, Cox S, Stillwell L, Peden DB, Bizon C, Krishnamurthy A, Tropsha A, Ahalt SC. A novel approach for exposing and sharing clinical data:the Translator Integrated Clinical and Environmental Exposures Service. Journal of the American Medical Informatics Association 2019;26(10):1064-1073 CR835785 (2018)
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Journal Article 12-hydroxy oleic acid impairs endothelium-dependent vasorelaxation. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH, PART A Bass VL, Snow S, Soukup J, Schladweiler M, Ghio A, Kodavanti U, Madden MC Bass VL, Snow S, Soukup J, Schladweiler M, Ghio A, Kodavanti U, Madden MC. 12-hydroxy oleic acid impairs endothelium-dependent vasorelaxation. Journal of Toxicology and Environmental Health, Part A 2019;82(5):383-6. CR835785 (2019)
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Journal Article Air Pollution Monitoring for Health Research and Patient Care. ANNALS OF THE AMERICAN THORACIC SOCIETY Cromar KR, Duncan BN, Bartonova A, Benedict K, Brauer M, Habre R, Hagler GS, Haynes JA, Khan S, Kilaru V, Liu Y Cromar KR, Duncan BN, Bartonova A, Benedict K, Brauer M, Habre R, Hagler GS, Haynes JA, Khan S, Kilaru V, Liu Y. Air Pollution Monitoring for Health Research and Patient Care. An Official American Thoracic Society Workshop Report. Annals of the American Thoracic Society 2019;16(10):1207-14. CR835785 (2019)
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Journal Article Aspirin pre-treatment modulates ozone-induced fetal growth restriction and alterations in uterine blood flow in rats. REPRODUCTIVE TOXICOLOGY Miller CN, Kodavanti UP, Stewart EJ, Schaldweiler M, Richards JH, Ledbetter AD, Jarrell LT, Snow SJ, Henriquez AR, Farraj AK, Dye JA Miller CN, Kodavanti UP, Stewart EJ, Schaldweiler M, Richards JH, Ledbetter AD, Jarrell LT, Snow SJ, Henriquez AR, Farraj AK, Dye JA. Aspirin pre-treatment modulates ozone-induced fetal growth restriction and alterations in uterine blood flow in rats. Reproductive Toxicology 2019;83:63-72. CR835785 (2019)
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Journal Article Can the effects of outdoor air pollution on asthma be mitigated?. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY Stevens EL, Rosser F, Forno E, Peden D, Celedón JC Stevens EL, Rosser F, Forno E, Peden D, Celedón JC. Can the effects of outdoor air pollution on asthma be mitigated?. Journal of Allergy and Clinical Immunology 2019;143(6):2016. CR835785 (2019)
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Journal Article Long chain lipid hydroperoxides increase the glutathione redox potential through glutathione peroxidase 4. BIOCHIMICA ET BIOPHYSICA ACTA (BBA)-GENERAL SUBJECTS Corteselli EM, Gibbs-Flournoy E, Simmons SO, Bromberg P, Gold A, Samet JM Corteselli EM, Gibbs-Flournoy E, Simmons SO, Bromberg P, Gold A, Samet JM. Long chain lipid hydroperoxides increase the glutathione redox potential through glutathione peroxidase 4. Biochimica et Biophysica Acta (BBA)-General Subjects 2019;1863(5):950-9. CR835785 (2019)
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Journal Article Semantic integration of clinical laboratory tests from electronic health records for deep phenotyping and biomarker discovery. NPJ DIGITAL MEDICINE Zhang XA, Yates A, Vasilevsky N, Gourdine JP, Callahan TJ, Carmody LC, Danis D, Joachimiak MP, Ravanmehr V, Pfaff ER, Champion J Zhang XA, Yates A, Vasilevsky N, Gourdine JP, Callahan TJ, Carmody LC, Danis D, Joachimiak MP, Ravanmehr V, Pfaff ER, Champion J. Semantic integration of clinical laboratory tests from electronic health records for deep phenotyping and biomarker discovery. NPJ digital medicine 2019;2(1):1-9. CR835785 (2019)
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Journal Article Smoldering and flaming biomass wood smoke inhibit respiratory responses in mice. INHALATION TOXICOLOGY Hargrove MM, Kim YH, King C, Wood CE, Gilmour MI, Dye JA, Gavett SH Hargrove MM, Kim YH, King C, Wood CE, Gilmour MI, Dye JA, Gavett SH. Smoldering and flaming biomass wood smoke inhibit respiratory responses in mice. Inhalation Toxicology 2019;31(6):236-47. CR835785 (2019)
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Journal Article Systemic inflammatory response to inhaled endotoxin does not correlate with airway response. RESPIRATORY RESEARCH Sood AK, Burbank AJ, Lawson M, Zhou H, Wells HB, Peden DB, Hernandez ML Sood AK, Burbank AJ, Lawson M, Zhou H, Wells HB, Peden DB, Hernandez ML. Systemic inflammatory response to inhaled endotoxin does not correlate with airway response. Respiratory research 2019;20(1):1-4. CR835785 (2019)
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Journal Article The role of fuel type and combustion phase on the toxicity of biomass smoke following inhalation exposure in mice. ARCHIVES OF TOXICOLOGY Kim YH, King C, Krantz T, Hargrove MM, George IJ, McGee J, Copeland L, Hays MD, Landis MS, Higuchi M, Gavett SH Kim YH, King C, Krantz T, Hargrove MM, George IJ, McGee J, Copeland L, Hays MD, Landis MS, Higuchi M, Gavett SH. The role of fuel type and combustion phase on the toxicity of biomass smoke following inhalation exposure in mice. Archives of toxicology 2019;93(6):1501-13. CR835785 (2019)
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Presentation Supplementation with the antioxidant sulforaphane does not protect airway epithelium against O3-induced injury in vivo. None Hernandez ML Hernandez ML. Supplementation with the antioxidant sulforaphane does not protect airway epithelium against O3-induced injury in vivo. Poster presentation at the American Academy of Allergy, Asthma, and Immunology, Los Angeles, CA, 2016. CR835785 (2015)
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Presentation Environmental factors contributing to severe asthma. None Peden DB Peden DB. Environmental factors contributing to severe asthma. Presented at Duke University Severe Asthma Conference–Mechanisms, Diagnosis, and Treatments, Searle Conference Center, Duke University, Durham, NC, October 3, 2015. CR835785 (2015)
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Presentation Translational studies of air pollution-induced inflammation. None Peden DB Peden DB. Translational studies of air pollution-induced inflammation. Invited Speaker. Presented at National Jewish Health, Denver, CO, January 14, 2016. CR835785 (2015)
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Presentation “Immunomodulation of Allergic Diseases”. None Peden DB Peden DB. “Immunomodulation of Allergic Diseases”. Presented at the Current Topics in Allergy and Clinical Immunology CME course, Division of Immunology, Department of Internal Medicine Grand Rounds, Carver College of Medicine, University of Iowa, Iowa City, Iowa. September 23, 2016. CR835785 (2016)
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Presentation “Influence of Environmental Factors on Asthma and COPD”. None Peden DB Peden DB. “Influence of Environmental Factors on Asthma and COPD”. Presented at the Life Spectrum of Asthma Meeting of the American Academy of Allergy, Asthma and Immunology, Chicago, IL, July 31, 2016. CR835785 (2016)
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Presentation “Pharmaceutical and Nutraceutical Interventions for Air Pollution induced Lung Disease”. None Peden DB Peden DB. “Pharmaceutical and Nutraceutical Interventions for Air Pollution induced Lung Disease”. Presented at Research Seminar, Xinxiang Medical University, School of Public Health, Xinxiang, Henan Province, China, September 20, 2017. CR835785 (2016)
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Presentation Core competencies & Convergence for personalized/global health. None Peden DB Peden DB. Core competencies & Convergence for personalized/global health. Presented at Institute for Biological Engineering Annual Meeting, Norfolk, VA, April 7, 2018. CR835785 (2017)
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Presentation “Interventions to reduce the impact of pollutants on allergic disease”, Presented at the Annual Meeting of the European Academy of Allergy and Clinical Immunology, June 18, 2017. None Peden DB Peden DB. “Interventions to reduce the impact of pollutants on allergic disease”, Presented at the Annual Meeting of the European Academy of Allergy and Clinical Immunology, June 18, 2017. CR835785 (2016)
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Presentation Alfalfa Sprouts rich in 17-β estradiol reduce O3-induced decrements in lung function. None Hernandez ML Hernandez ML. Alfalfa Sprouts rich in 17-β estradiol reduce O3-induced decrements in lung function. Poster discussion session at the American Thoracic Society, Denver, CO, 2015. CR835785 (2015)
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Presentation Adverse health effects and disease due to air pollution. None Peden DB Peden DB. Adverse health effects and disease due to air pollution. Presented at 2016 Frank P. Anderson, MD Memorial Lecture, Children’s Hospital of Georgia & Department of Pediatrics, Medical College of Georgia, Augusta University, Augusta, Georgia, June 17, 2016. CR835785 (2015)
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Presentation Development of Interventions for PM Induced Airway and Systemic Disease. None Peden DB Peden DB. Development of Interventions for PM Induced Airway and Systemic Disease. Presented at NIEHS Symposium Indoor exposure to biomass/woodsmoke exposure and pulmonary health, American Thoracic Society International Conference, San Francisco, CA May 15, 2016. CR835785 (2015)
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Presentation Effects of Wood Smoke Exposure on Nasal Mucosal Host Defense Responses After Infection with Live-Attenuated Influenza Virus. None Jaspers I Jaspers I. Effects of Wood Smoke Exposure on Nasal Mucosal Host Defense Responses After Infection with Live-Attenuated Influenza Virus. Presented at ATS, San Francisco, CA 2016. CR835785 (2015)
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Presentation Performance characteristics of the ACQ-6 for predicting poorly controlled asthma in African-American teens. None ML Hernandez, A Burbank, SC Grabich, KE Todorich, M Frye, CE Loughlin, C Robinette, K Mills, DB Peden ML Hernandez, A Burbank, SC Grabich, KE Todorich, M Frye, CE Loughlin, C Robinette, K Mills, and DB Peden. Performance characteristics of the ACQ-6 for predicting poorly controlled asthma in African-American teens. Poster presentation at the American Academy of Allergy, Asthma, and Immunology, Atlanta, GA 2017. CR835785 (2016)
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Presentation Air Pollution and Allergy. None Peden DB Peden DB. Air Pollution and Allergy. Presented at Joint Congress of the APAAACI & APAPARI, Bangkok, Thailand, 10-13-2018. CR835785 (2018)
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Presentation Global perspective of air pollution on allergy prevalence and relapse. None Peden DB Peden DB. Global perspective of air pollution on allergy prevalence and relapse. Presented at Joint Congress of the APAAACI & APAPARI, Bangkok, Thailand, 10-14-2018. CR835785 (2018)
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Presentation Keynote Speaker, Environmental Impacts on Pollen and Wildfire Effects on Human Health. None Peden DB Peden DB. Keynote Speaker, Environmental Impacts on Pollen and Wildfire Effects on Human Health. Presented at CSTE Climate & Respiratory Health Meeting, Centers for Disease Control and Prevention, Atlanta, GA, March 15, 2018. CR835785 (2017)
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Presentation The Impact of Air Pollution on the Epigenetics of Allergic Disease and Asthma. None Peden DB Peden DB. The Impact of Air Pollution on the Epigenetics of Allergic Disease and Asthma. Presented At Annual Meeting, American College of Allergy, Asthma and Immunology, Seattle, WA, 11-17-2018. CR835785 (2018)
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Presentation Indoor Biomass and Wildfire Exposure and Human Health. None Peden DB Peden DB. Indoor Biomass and Wildfire Exposure and Human Health. Presented at Annual Meeting, Western Society of Allergy, Asthma and Immunology, Maui, HI, 1-22-2019. CR835785 (2018)
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Presentation Piecing Together the Puzzle:Identifying the Role Oxidative Stress and the Alveolar Epithelium Play in Air Pollution Induced Cardiovascular Disease. None Eva CM, Vituccii, McCullough S Eva CM, Vituccii, McCullough S. Piecing Together the Puzzle:Identifying the Role Oxidative Stress and the Alveolar Epithelium Play in Air Pollution Induced Cardiovascular Disease. Presented at the Society of Toxicology, Baltimore, MD, 2019. CR835785 (2019)
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Presentation Systemic and Airway Neutrophilic Inflammation Do Not Correlate in Response to Inhaled Endotoxin Challenges. None A Sood, AJ Burbank, HB Wells, M Lawson, H Zhou, DB Peden, ML Hernandez A Sood, AJ Burbank, HB Wells, M Lawson, H Zhou, DB Peden, ML Hernandez. Systemic and Airway Neutrophilic Inflammation Do Not Correlate in Response to Inhaled Endotoxin Challenges. Presented at the AAAAI 2019 meeting, San Francisco, 2019. CR835785 (2019)
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Presentation The Effect of Air Pollutants on Asthma, Allergic and Immunologic Disease. None Peden DB Peden DB. The Effect of Air Pollutants on Asthma, Allergic and Immunologic Disease. Presented at Annual Meeting, Western Society of Allergy, Asthma and Immunology, Maui, HI, 1-23-2019. CR835785 (2018)
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Presentation “Climate Change and the Impact on Allergic Conditions”. None Peden DB Peden DB. “Climate Change and the Impact on Allergic Conditions”. Presented at the Annual meeting of the American College of Allergy, Asthma and Immunology, November, 2019. CR835785 (2019)
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Presentation “Effects of air pollution on human health and inflammation”. None Peden DB Peden DB. “Effects of air pollution on human health and inflammation”. Presented at the 2019 Joint Meeting of the Asian Pacific Association of Allergy, Asthma and Clinical Immunology and the Chinese Society of Allergy, Beijing, China, September, 2019. CR835785 (2019)
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Presentation The Ann O'Neill Shigeoka Memorial Lecture:Air Pollution and Lung Disease. None Peden, DB Peden, DB. The Ann O'Neill Shigeoka Memorial Lecture:Air Pollution and Lung Disease. Presented at the Grand Rounds, Department of Pediatrics, University of Utah, January, 2020. CR835785 (2019)
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Presentation Paul M. None Peden DB Peden DB. Paul M. and Dorothy E. Seebohm Visiting Lectureship in Allergy “Environmental Impact on Asthma and Allergic Diseases”, Presented at the Department of Internal Medicine Grand Rounds, Carver College of Medicine, University of Iowa, Iowa City, Iowa. September 22, 2016. CR835785 (2016)
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Presentation Environmental Impacts on Asthma:Biology to Intervention. None Peden DB Peden DB. Environmental Impacts on Asthma:Biology to Intervention. AAAAI Foundation and I. Leonard Bernstein, MD FAAAAI Memorial Lectureship, Presented in the Presidential Plenary Session at the Annual Meeting of the American Academy of Allergy, Asthma and Immunology, March 2, 2018, Orlando, FL. CR835785 (2017)
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Presentation M. None Eva C Eva C.M. Vitucci & Shaun D. McCullough. Piecing Together the Puzzle:Identifying the Role Oxidative Stress and the Alveolar Epithelium Play in Air Pollution Induced Cardiovascular Disease. Presented at the Genetics and Environmental Mutagenesis Society Meeting, Chapel Hill, NC, 2018. CR835785 (2019)
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Presentation May 2017. None Jaspers I Jaspers I. Translational Approaches to Understand the Effects of Biomass Smoke. Presented at American Thoracic Society Meeting, Washington, DC. May 2017 CR835785 (2016)
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Presentation Presented at the School of Public Health, Beijing University, Beijing, China, September, 2019. None Peden DB “Determinants of Human Response to Air Pollutants” Peden DB “Determinants of Human Response to Air Pollutants”. Presented at the School of Public Health, Beijing University, Beijing, China, September, 2019. CR835785 (2019)
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Presentation “Environmental Impacts on Allergic Disease” Asthma & Allergy Foundation of America, Presented at Alaska Chapter 12th Annual Alaska Asthma & Allergy Conference, Girdwood, AK, September 8-9, 2017. None Peden DB Peden DB. “Environmental Impacts on Allergic Disease” Asthma & Allergy Foundation of America, Presented at Alaska Chapter 12th Annual Alaska Asthma & Allergy Conference, Girdwood, AK, September 8-9, 2017. CR835785 (2016)
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Presentation “Pollutants and Asthma”, Presented at Allergy/Immunology Grand Rounds, Presented at University of Wisconsin, Madison, Wisconsin, Februrary 1, 2017. None Peden DB Peden DB. “Pollutants and Asthma”, Presented at Allergy/Immunology Grand Rounds, Presented at University of Wisconsin, Madison, Wisconsin, Februrary 1, 2017. CR835785 (2016)
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